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Total Results: 13059 Pages: Previous [1] 2 3 4 5 6 7 8 9 10 11 Next Results per page:
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Numerical Optimization of an Annular Field Reserved Configuration Translation Experiment 14-Aug-2009 16 pages
Authors:  Lyon B King; Carrie S Niemela; AIR FORCE RESEARCH LAB EDWARDS AFB CA PROPULSION DIRECTORATE
The full text of this report is available for sale.Annular field reversed configuration (AFRC) devices form annular plasma toroids between a pair of concentric cylindrical coils. This plasmoid remains detached from the external magnetic _field so that it can be ejected from the coils, making AFRCs viable pulsed inductive plasma accelerators. Though numerous formation studies on AFRCs are available, no successful translation studies have been published. Michigan Technological University, in conjunction with the Air Force Research Laboratory, is investigating ...


Software Exploit Prevention and Remediation via Software Memory Protection May-2009 28 pages
Authors:  Anh Nguyen-Tuong; Clark L Coleman; Michele Co; Jack W Davidson; John C Knight; Jason D Hiser; VIRGINIA UNIV CHARLOTTESVILLE
The full text of this report is available for sale.Deployed software often contains memory overwriting vulnerabilities which can be exploited by malicious users who provide input that causes critical data to be overwritten in the program (called a memory overwriting exploit). There are a wide variety of such exploits (e.g. buffer overflows, formatting string exploits, etc.). Some defenses have been limited to defeating memory overwrites in heap or stack memory, and most defenses require access to source code. The ...


Dynamic Personal Identity and the Dynamic Identity Grid: How Theory and Concept Can Transform Information into Knowledge and Secure the American Homeland 01-Sep-2008 130 pages
Authors:  Ryan Burchnell; NAVAL POSTGRADUATE SCHOOL MONTEREY CA
The full text of this report is available for sale.Personal identification systems and processes; including those used for transliteration, travel visas and driver licenses; have failed to adequately adapt to the nation's new asymmetric threat. After September 11th, personal identification information about the attackers began to emerge and it became clear that it could have been used to identify the attackers prior to their terrorist acts. This study used qualitative research methods to construct meaning from previously uncorrelated issues ...


AGILE: Autonomous Global Integrated Language Exploitation APR 2008 36 pages
Authors:  John Makhoul; BBN TECHNOLOGIES CAMBRIDGE MA
The full text of this report is available for sale.The objective of GALE is nothing short of solving the human language technology (HLT) problem of transcribing foreign spoken and written languages into English and distilling the transcription into accurate information for use by our military. Below, we summarize the work performed by the BBN-led AGILE Team in Year 2. A more detailed description of the work performed can be found in the DARPA/IPTO Quarterly Status Reports for this project. ...


From Indexed Lax Logic to Intuitionistic Logic 07 JAN 2008 37 pages
Authors:  Deepak Garg; Michael C. Tschantz; CARNEGIE-MELLON UNIV PITTSBURGH PA SCHOOL OF COMPUTER SCIENCE
The full text of this report is available for sale.We present translations from a logic with indexed lax modalities to first-order intuitionistic logic and intuitionistic linear logic. These translations rely on a continuation passing style encoding for the lax modalities. We show that our translations preserve provability of formulas.


South China Sea Wave Characteristics During Typhoon Muifa Passage in Winter 2004 01-Jan-2008 49 pages
Authors:  Kuo-Feng Cheng; Peter C Chu; NAVAL POSTGRADUATE SCHOOL MONTEREY CA NAVAL OCEAN ANALYSIS AND PREDICTION LAB
The full text of this report is available for sale.Ocean wave characteristics in the western Atlantic Ocean (Hurricane Region) to tropical cyclones have been investigated extensively, but not the regional seas in the western Pacific such as the South China Sea (Typhoon Region). This is due to the lack of observational and modeling studies in western Pacific regional seas. To fill this gap, Wavewatch-III (WW3) is used to study the response of the South China Sea (SCS) to Typhoon ...


Al-Qa'ida's Foreign Fighters in Iraq: A First Look at the Sinjar Records DEC 2007 31 pages
Authors:  Joseph Felter; Brian Fishman; MILITARY ACADEMY WEST POINT NY COMBATING TERRORISM CENTER
The full text of this report is available for sale.On December 4, 2007 Abu Umar al-Baghdadi, the reputed Emir of al-Qa'ida's Islamic State of Iraq (151), claimed that his organization was almost purely Iraqi, containing only 200 foreign fighters. Twelve days later, on December 16, 2007, Ayman al-Zawahiri urged Sunnis in Iraq to unite behind the 151. Both statements are part of al-Qa'ida's ongoing struggle to appeal to Iraqis, many of whom resent the ISI's foreign leadership and its ...


High Density Magnetized Toroid Formation and Translation with XOCOT: An Annular Field Reversed Configuration Plasma Concept (Preprint) SEP 2007 51 pages
Authors:  David Kirtley; Alec D. Gallimore; James Haas; Michael Reilly; AIR FORCE RESEARCH LAB EDWARDS AFB CA PROPULSION DIRECTORATE
The full text of this report is available for sale.An annular field reversed configuration (FRC) plasma concept is being developed by the University of Michigan and AFRL to investigate inductively-coupled high power electric propulsion. Presented is the continued exploration of an annular FRC with specific focus on main bank discharges, magnetized plasma toroid formation, and preliminary investigation into plasma translation. Additional detail is given towards discharge parameter space, optimization of energy input/translation, and predictive scaling laws of magnetic flux, ...


Early Detection of Breast Cancer by Fluorescence Molecular Tomography JUL 2007 34 pages
Authors:  Vasilis Ntziachristos; MASSACHUSETTS GENERAL HOSPITAL BOSTON
The full text of this report is available for sale.Molecular targeting approaches have tremendous potential for early-detection because they rely on elucidation of abnormal gene-expression, rather than on discovery of retarded anatomical changes inflicted by growing tumors upon their microenvironment. We investigated whether fluorescence molecular tomography (FMT) could be used to detect breast cancer at its earliest stages via the detection of injected, protease-activatable molecular probes. We have successfully completed all goals and achieved the three major aims of ...


Control of DNA Dehybridization via Nanoparticle Antennas for Antisense Gene Therapy 2007
Authors:  Kimberly Hamad-Schifferli; MASSACHUSETTS INST OF TECH CAMBRIDGE
The full text of this report is not available and therefore is not for sale. This information is provided for reference purposes only.The goal of this proposal is to develop the use of a nanoscale interface to protein translation machinery to control translation. External magnetic fields excite the nanoscale interface and thus switch on translation of a protein. This technique would enable time-specific control of protein expression, and would enable new techniques in disease diagnosis and therapy. These objectives are in line with the original proposal.


Efficacy in Automated Language Translators 01-Nov-2006 5 pages
Authors:  John Graham; Ian McCulloh; Jillian Morton; Jennifer K Jantzi; Amy M Rodriguez; MILITARY ACADEMY WEST POINT NY
The full text of this report is available for sale.This paper suggests an improved measure for evaluating the usefulness of automated machine language translators. With the Global War on Terror (GWOT), the Army has increasing interest and need for accurate language translation more than ever. Today, there are approximately 20,000 linguists with language training in either the Active Duty or Reserve components of the U.S. Army. Coalition operations and U.S. presence in Iraq, Kuwait, and other areas in the ...


Militant Ideology Atlas: Research Compendium NOV 2006 362 pages
Authors:  William McCants; Jarret Brachman; Joseph Felter; MILITARY ACADEMY WEST POINT NY COMBATING TERRORISM CENTER
The full text of this report is available for sale.The Combating Terrorism Center (CTC) at West Point has dedicated many of its resources this year to understanding the Jihadi ideology through the words of its adherents. In its "Harmony and Disharmony" report, the CTC exposed the organizational weaknesses of al-Qaida using its own internal documents. CTC's "Jihadi Imagery Report" cataloged frequently used images in Jihadi propaganda. The translation of Abu Bakr Naji's "Management of Savagery" focused new attention on ...


Design, Implementation and Testing of a Common Data Model Supporting Autonomous Vehicle Compatibility and Interoperability SEP 2006 359 pages
Authors:  Duane T. Davis; NAVAL POSTGRADUATE SCHOOL MONTEREY CA
The full text of this report is available for sale.Current autonomous vehicle interoperability is limited by vehicle-specific data formats and support systems. Until a standardized approach to autonomous vehicle command and control is adopted, true interoperability will remain elusive. This work explores the applicability of a data model supporting arbitrary vehicles using the Extensible Markup Language (XML). An exemplar, the Autonomous Vehicle Command Language (AVCL), encapsulates behavior-scripted mission definition, goalbased mission definition, inter-vehicle communication, and mission results. Broad applicability ...


Posttranscriptional Regulation of the Neurofibromatosis 2 Gene JUL 2006 122 pages
Authors:  Long-Sheng Chang; CHILDREN'S HOSPITAL COLUMBUS OH
The full text of this report is available for sale.Neurofibromatosis type 2 (NF2) is associated with a homozygous inactivation of the neurofibromatosis 2 (NF2) gene. Despite intense study of the NF2 gene, the mechanism by which the NF2 tumor suppressor acts to prevent tumor formation is not well understood. The goal of this research is to examine the role of posttranscriptional regulation of the NF2 gene. With this grant support, we have confirmed that vestibular schwannomas express a distinct ...


Radiation Dosimetry from Intratumoral Injection of Radionuclides in Human Breast Cancer JUL 2006 66 pages
Authors:  Franklin C. Wong; M D ANDERSON CANCER CENTER HOUSTON TX
The full text of this report is available for sale.This study has been designed to evaluation the sequestration of proprietary radiopharmaceuticals Radioactive Gallium Iron Macroaggregates (GIMA) after intratumoral injection. Our team has adopted a 2-prong approach. While the official approval of the human protocol is ongoing, we continue on translation studies using in vivo imaging methods to investigate our institution-approved animal tumor models in rats and dogs. We made revisions the approved human protocol and received preliminary approval from ...


Post-Transcriptional Regulation of MKK4-A Stress Signaling Kinase Implicated in the Regulation of Metastatic Growth APR 2006 23 pages
Authors:  Carrie W. Rinker-Schaeffer; CHICAGO UNIV IL
The full text of this report is available for sale.Mitogen-activated protein kinase kinase 4 (MKK4) is a dual-specificity kinase with a critical role in regulating the activity of the c-Jun-N-terminal kinase (JNK) and p38 kinases. We identified a novel biological function for MKK4 in the regulation of growth of ovarian and prostate cancer metastases. Previous clinical correlative studies showed that MKK4 protein levels were reduced in high-grade prostate cancer and prostate and ovarian cancer metastases as compared to normal ...


Typhoon Effects on the South China Sea Wave Characteristics During Winter Monsoon MAR 2006 114 pages
Authors:  Kuo-Feng Cheng; NAVAL POSTGRADUATE SCHOOL MONTEREY CA
The full text of this report is available for sale.Ocean wave characteristics in the western Atlantic Ocean (Hurricane Region) to tropical cyclones have been well identified, but not the regional seas in the western Pacific, e.g., the South China Sea (Typhoon Region). This is due to the lack of observational and modeling studies in the regional seas of the western Pacific. To fill this gap, Wavewatch-III (WW3) is used to study the response of the South China Sea (SCS) ...


Initial Documentation Requirements for a High Assurance System: Lessons Learned FEB 2006 17 pages
Authors:  Paul C. Clark; Cynthisa E. Irvine; Timothy E. Levin; Thuy D. Nguyen; David J. Shifflett; Donna Miller; NAVAL POSTGRADUATE SCHOOL MONTEREY CA DEPT OF COMPUTER SCIENCE
The full text of this report is available for sale.The Center for Information Systems Security Studies and Research (CISR) is working on a project known as the Trusted Computing Exemplar (TCX). This project is developing a high assurance computing component that will be evaluated at the Common Criteria (CC) Evaluation Assurance Level 7 (EAL7). The processes, documentation, source code, and other evidence to support the evaluation will be openly shared. Documentation is a substantial part of this evidence. Although ...


Automated Tools for Mapping Among Ontologies FEB 2006 23 pages
Authors:  Drew McDermott; YALE UNIV NEW HAVEN CT DEPT OF COMPUTER SCIENCE
The full text of this report is available for sale.The Yale/BBN effort was focused on developing techniques for implementing and managing ontology translations. The simplest case is translation of datasets or queries expressed using one ontology into datasets or queries expressed in another. They devised and implemented the merging-deduction- projection model: Bridging axioms are stored in merged ontologies; a set of facts to translate are used to start forward chaining using the bridging axioms; conclusions in the target ontology ...


Functional Characterization of Two Novel Human Prostate Cancer Metastasis Related Genes FEB 2006 12 pages
Authors:  Asim B. Abdel-Mageed; Krishna C. Agrawal; Jr Crawford Byron; TULANE UNIV NEW ORLEANS LA
The full text of this report is available for sale.We propose to identify the functional characterization of two novel cancer-specific, metastasis-related genes whose constitutive expression may be pivotal for prostate cancer progression. Work accomplished in the first year was performed based on the proposed statement of work. We have characterized the full-length cDNAs of the Seq1 and Seq2 genes using at least three 5 and 3 rapid amplification of cDNA ends (RACE) commercial kits (Invitrogen Carlsbad, CA, BD Bioscience ...


TREC-9 Experiments at Maryland: Interactive CLIR 2006 8 pages
Authors:  Douglas W. Oard; Gina-Anne Levow; Clara I. Cabezas; MARYLAND UNIV COLLEGE PARK INST FOR ADVANCED COMPUTER STUDIES
The full text of this report is available for sale.The University of Maryland team participated in the TREC-9 Cross-Language Information Retrieval Track, with the goal of exploring evaluation paradigms for interactive cross-language retrieval. Participants were asked to examine gloss translations of highly ranked documents and make relevance judgments, and those judgments were used to produce a new ranked list in which documents assessed as relevant were promoted and those assessed as nonrelevant were demoted. No improvement over fully automatic ...


Synthesis of Self-Timed Circuits by Program Transformation 2006 20 pages
Authors:  Steven M. Burns; Alain J. Martin; CALIFORNIA INST OF TECH PASADENA DEPT OF COMPUTER SCIENCE
The full text of this report is available for sale.Self-timed circuits can be synthesized from concurrent programs in two logically separate phases. First, through a series of program transformations, the source program is decomposed into an equivalent program constructed entirely from instances of basic processes. These basic processes correspond to the syntactic constructs of the source language. The remainder of the synthesis procedure consists of compiling each of the basic processes into a self-timed circuit using techniques described in ...


Adits, Caves, Karizi-Qanats, and Tunnels in Afghanistan: An Annotated Bibliography 30 NOV 2005 86 pages
Authors:  Robert L. Hadden; ENGINEER RESEARCH AND DEVELOPMENT CENTER ALEXANDRIA VA TOPOGRAPHIC ENGINEERING CENTER
The full text of this report is available for sale.This bibliography on the caves, tunnels, and other geological features of Afghanistan was begun in September 2001. The work brings together selected citations from a variety of different cartographic, geological, and speleological resources and specialized library collections. Publication dates range from 1830 to 2005. Resources cover books, journal articles, newspaper articles, reports, and maps from a variety of government and private library and geological information centers in Arabic, English, French, ...


A Double Selection Approach to Achieve Specific Expression of Toxin Genes for Ovarian Cancer Gene Therapy NOV 2005 80 pages
Authors:  David T. Curiel; Gene Siegal; Minghui Wang; ALABAMA UNIV IN BIRMINGHAM
The full text of this report is available for sale.Gene therapy is a novel treatment modality which offers great potential for the control of carcinoma of the ovary. The efficacy of such approaches, however, is currently limited due to the inability of available gene delivery vehicles (vectors) to achieve efficient and selective gene transfer to target tumor cells. Proposed herein is a strategy to modify one candidate vector, recombinant adenovirus, such that it embodies the requisite properties of efficacy ...


Memory System Support for Image Processing 19 OCT 2005 18 pages
Authors:  Lixin Zhang; John B. Carter; Wilson C. Hsieh; Sally A. McKee; UTAH UNIV SALT LAKE CITY DEPT OF COMPUTER SCIENCE
The full text of this report is available for sale.Processor speeds are increasing rapidly, but memory speeds are not keeping pace. Image processing is an important application domain that is particularly impacted by this growing performance gap. Image processing algorithms tend to have poor memory locality because they access their data in a non-sequential fashion and reuse that data infrequently. As a result, they often exhibit poor cache and TLB hit rates on conventional memory systems, which limits overall ...


The Role of Protein Elongation Factor eEF1A2 in Breast Cancer SEP 2005 33 pages
Authors:  Jonathan M. Lee; HAMILTON REGIONAL CANCER CENTRE (ONTARIO)
The full text of this report is available for sale.The overall goal of the project is to explore the role of protein elongation factor eEFlA2 in breast tumour development and to determine whether eEF1A2 is a useful breast cancer prognostic factor. Elongation factor eEF1A2 is one of two members of the eEF1A family of proteins (eEF1A1 and eEF1A2) that bind amino-acylated tRNA and facilitate their recruitment to the ribosome during protein translation elongation[l]. eEFlA proteins have other functions and ...


A Test for Non-Disclosure in Security Level Translations 24 AUG 2005 17 pages
Authors:  David Rosenthal; Francis Fung; ODYSSEY RESEARCH ASSOCIATES INC ITHACANY
The full text of this report is available for sale.Two security domains that want to exchange information security may need to agree on translations of Mandatory Access Control (MAC) labels of their information, if their MAC labels have a different syntax or semantics. It is desirable that these translations do not introduce any confidentiality violations. In this paper we present a property, the Security Level Translation Property (SLTP), which must hold if the security level translation functions satisfy MAC ...


Agent Semantic Communication Services 17 AUG 2005 33 pages
Authors:  John Li; Allan Terry; TEKNOWLEDGE CORP PALO ALTO CA
The full text of this report is available for sale.Agent Semantic Communication Services (ASCS) addressed a fundamental issue in the adoption and use of semantic technologies. It provided a semantic search engine with Web-scale architecture. Semantic search answers a logical query by return bindings for the unbound variables in the query. In information retrieval approaches such as Google, a large number of URIs are returned that contain one or more of the search keywords, ranked by an estimate of ...


Cooperative Relational Database Initiative for Threat Reduction 17 AUG 2005 5 pages
Authors:  Michelle Sheahan; Luther E. Lindler; WALTER REED ARMY INST OF RESEARCH SILVER SPRING MD
The full text of this report is available for sale.In order to create a resource for basic and clinical research in biological threat reduction, we have developed an annotated relational database. This database is comprised of gene sequences from public databases and researchers' laboratory results, the Bioterrorism Defense Database runs on Microsoft SQL platform and is accessible on a password-protected Internet site. The Biodefense database project is a collaborative effort between the Walter Reed Army Institute of Research, the ...


A Paraphrase-Based Approach to Machine Translation Evaluation AUG 2005 12 pages
Authors:  Grazia Russo-Lassner; Jimmy Lin; Philip Resnik; MARYLAND UNIV COLLEGE PARK INST FOR ADVANCED COMPUTER STUDIES
The full text of this report is available for sale.We propose a novel approach to automatic machine translation evaluation based on paraphrase identification. The quality of machine-generated output can be viewed as the extent to which the conveyed meaning matches the semantics of reference translations, independent of lexical and syntactic divergences. This idea is implemented ill linear regression models that attempt to capture human judgments of adequacy and fluency, based on features that have previously been shown to be ...


Promoter and Cofactor Requirements for SERM-ER Activity MAY 2005 15 pages
Authors:  Jason Carroll; DANA-FARBER CANCER INST BOSTON MA
The full text of this report is available for sale.The mechanisms of estrogen-mediated transcription are not completely understood and as such, the roles of Selective Estrogen Receptor Modulators (SERMs), such as tamoxifen are also poorly understood. Our current work is focused on assessing the relative contributions of the specific promoter sequences within estrogen target genes and how they influence the transcriptional activity by different ligands. Specifically, we have generated breast (MCF-7) and endometrial (ECC1) cancer cell lines with a ...


Intelligence Professionalism in the Americas (profesionalismo de inteligencia en las americas) NOV 2004 586 pages
Authors:  Russell G. Swenson; Susana C. Lemozy; JOINT MILITARY INTELLIGENCE COLL WASHINGTON DC
The full text of this report is available for sale.Numerous individuals contributed directly and indirectly to the development and completion of this supranational project. It is impossible to name them all, but those who deserve special mention are Major Clif Prat, (U.S. Army) and senior DIA official Rix Mills, both of whom contributed substantially to the accurate translation of South American varieties of Spanish. U.S. State Department foreign service officer and distinguished JMIC faculty member Jon Wiant volunteered his ...


Differential Gene Expression in Mammalian Liver During Hibernation 13 SEP 2004 4 pages
Authors:  Sandra L. Martin; Elaine Epperson; CALIFORNIA UNIV IRVINE DEPT OF CHEMISTRY
The full text of this report is available for sale.The long-range goal of this project is to understand what molecular changes allow some mammals to achieve and survive hibernation so that these molecular mechanisms may be engineered to evoke similar hypometabolic states in humans. Earlier results supported the hypothesis that differential gene expression is significant for determining the hibernating phenotype. Thus, one objective of this work has been to identify gene products that are differentially expressed during hibernation in ...


Implementation of a Network Address Translation Mechanism Over IPv6 JUN 2004 270 pages
Authors:  Trevor J. Baumgartner; Matthew D. Phillips; NAVAL POSTGRADUATE SCHOOL MONTEREY CA
The full text of this report is available for sale.Network Address Translation (NAT) for IPv4 was developed primarily to curb overcrowding of the Internet due to dwindling global IP addresses; however, NAT provides several other benefits. NAT can be used to mask the internal IP addresses of an Intranet - IPv6, the emerging standard for Internet addressing, provides three times the number of bits for IP addressing. While IPv6 does not need NAT for connectivity, other NAT features such ...


Breaking the Code to Quality Improvement of Medical Report Translations (A Retrospective Analysis) APR 2004 54 pages
Authors:  Timothy A. Sharpe; ACADEMY OF HEALTH SCIENCES (ARMY) FORT SAM HOUSTON TX HEALTH CARE ADMINISTRATION
The full text of this report is available for sale.Over the past year, the 67th Combat Support Hospital/WMEDDAC has accumulated a backlog of over 4,000 pages of network provider medical reports awaiting translation. Throughout the Europe Regional Medical Command military medical treatment facilities have had varying degrees of difficulty with the timely translation of medical reports. However, at 4,000 pages, the 67th CSH/ WMEDDAC has the greatest amount of accumulated medical reports awaiting translation services. The patient medical record ...


Translation from Russian to English the Book "Blast Effects Caused by Explosions" Authored by B. Gelfand and M. Silnikov APR 2004 250 pages
Authors:  Boris Gelfand; M. Silnikov; EUROPEAN RESEARCH OFFICE LONDON (UNITED KINGDOM)
The full text of this report is available for sale.This report contains the translation from Russian to English of the book Blast effects caused by explosions" authored by B. Gelfand and M. Silnikov.


Geographically Locating an Internet Node Using Network Latency Measurement MAR 2004 110 pages
Authors:  Eugene D. Turnbaugh; AIR FORCE INST OF TECH WRIGHT-PATTERSON AFB OH SCHOOL OF ENGINEERING AND MANAGEMENT
The full text of this report is available for sale.Discovering the geographic location of a node using only its Internet Protocol (IP) address and latency measurements is a big challenge. The difficulties include accurate latency measure, network address translation (NAT) masking, service blocking, disparate physical configuration, dissimilar network hardware, and inaccurate and limited measuring tools. Using only latency measurements from the Internet, this research successfully geolocated the nearest city to a destination node 100 percent of the time to ...


Die Liberalisierung de Telekommunikationsbranche in Deutschland( The Liberalization of the Telecommunication-Industry in Germany) MAR 2004 41 pages
Authors:  Ralf Dewenter; Justus Haucap; UNIVERSITAET DER BUNDESWEHR MUENCHEN NEUBIBERG (GERMANY F R) FAKULTAET FUER LUFT- UND RAUMFAHRTTECHNIK
The full text of this report is available for sale.There was a duet-pole-competition at least since 1991. Since the market-opening in the year 1998, however, the German telecommunication-industry has, like the telecommunication in other European countries, had dramatic development experiences: Numerous new suppliers of telecommunication-services have the market or, said more exactly, have markets with more favorable and/or innovative offers. Vehement price-adaptations (mostly markdowns) and market share-postponements were the consequence of the corresponding consequences of consumers and suppliers. The ...


The Integrated Data Environment: A New Tool for Interoperability and Effective Data Integration for Command and Control MAR 2004
Authors:  Jon Wilkes; NATO C3 AGENCY THE HAGUE (NETHERLANDS)
The full text of this report is not available and therefore is not for sale. This information is provided for reference purposes only.NATO nations still have a plethora of incompatible data systems that are likely to remain in service for many years. A fusion approach is not appropriate, and is likely to prove unmanageable and unaffordable. The Integrated Data Environment provides a response to this information management challenge that is both manageable and affordable, and is eminently suitable for an incremental growth approach. The NATO C3 Agency has responded to customer requirements ...


Minimum Bayes-Risk Decoding for Statistical Machine Translation 2004 9 pages
Authors:  Shankar Kumar; William Byrne; JOHNS HOPKINS UNIV BALTIMORE MD CENTER FOR LANGUAGE AND SPEECH PROCESSING (CLSP)
The full text of this report is available for sale.We present Minimum Bayes-Risk (MBR) decoding for statistical machine translation. This statistical approach aims to minimize expected loss of translation errors under loss functions that measure translation performance. We describe a hierarchy of loss functions that incorporate different levels of linguistic information from word strings, word-to-word alignments from an MT system, and syntactic structure from parse-trees of source and target language sentences. We report the performance of the MBR decoders ...


Antibody Probes to Transcript-Specific Peptides Provide a Novel Tool to Investigate the Role of Alternate Estrogen Receptor Promotor Use in Breast Cancer JUL 2003 25 pages
Authors:  Brian T. Pentecost; HEALTH RESEARCH INC RENSSELAER NY
The full text of this report is available for sale.Estrogen receptor alpha (ER) plays an important role in the development and progression of breast cancer, and it is routinely used as a marker for hormone sensitivity in breast cancer patients. Positive ER status is a useful indicator for a first-line therapy with antiestrogens. ER is expressed from at least two promoters (Fig.l) . The resulting transcripts from these two promoters differ only in the non-coding region upstream of the ...


Intelligent Systems for Aeronautics (Systemes Intelligents pour l'Aeronautique) (CD-ROM) JUN 2003
Authors:  NATO RESEARCH AND TECHNOLOGY ORGANIZATION NEUILLY-SUR-SEINE (FRANCE)
The full text of this report is not available and therefore is not for sale. This information is provided for reference purposes only.ELECTRONIC FILE CHARACTERISTICS: 21 files; Adobe Acrobat (.PDF) and MS Word (.DOC). PHYSICAL DESCRIPTION: 1 computer laser optical disc (CD-ROM); 4 3/4 in.; 36.8 MB. SYSTEMS DETAIL NOTE: IBM-clone PC-compatible; Adobe Acrobat Reader is included on disc. ABSTRACT: Intelligent systems are suited as search and optimization, pattern recognition and matching, planning, uncertainty management control and adaptation. These lecture notes cover techniques and application with emphasis on aeronautical and space applications. ...


Distributed Architecture for the Object-Oriented Method for Interoperability MAR 2003 157 pages
Authors:  George M. Lawler; NAVAL POSTGRADUATE SCHOOL MONTEREY CA
The full text of this report is available for sale.The Department of Defense (DoD) is both challenged by the quest for interoperability and capable of the bottom-up development of a solution. The predominant method for achieving interoperability is the development of an intermediate representation that provides a common integration language or data model. An example is Young's Object-Oriented Method for Interoperability (OOMI), which produces a Federation Interoperability Object Model (FIOM) for the resolution of heterogeneities in representation and view ...


Syntax-based Alignment of Multiple Translations: Extracting Paraphrases and Generating New Sentences 2003 9 pages
Authors:  Bo Pang; Kevin Knight; Daniel Marcu; CORNELL UNIV ITHACA NY DEPT OF COMPUTER SCIENCE
The full text of this report is available for sale.We describe a syntax-based algorithm that automatically builds Finite State Automata (word lattices) from semantically equivalent translation sets. These FSAs are good representations of paraphrases. They can be used to extract lexical and syntactic paraphrase pairs and to generate new, unseen sentences that express the same meaning as the sentences in the input sets. Our FSAs can also predict the correctness of alternative semantic renderings, which may be used to ...


A Phrase-Based, Joint Probability for Statistical Machine Translation JUL 2002 8 pages
Authors:  Daniel Marcu; William Wong; UNIVERSITY OF SOUTHERN CALIFORNIA MARINA DEL REY INFORMATION SCIENCES INST
The full text of this report is available for sale.We present a joint probability model for statistical machine translation, which automatically learns word and phrase equivalents from bilingual corpora. Translations produced with parameters estimated using the joint model are more accurate than translations produced using IBM Model 4.


Discovering Frequent Geometric Subgraphs 17 JUN 2002 19 pages
Authors:  Michihiro Kuramochi; George Karypis; MINNESOTA UNIV MINNEAPOLIS DEPT OF COMPUTER SCIENCE
The full text of this report is available for sale.As data mining techniques are being increasingly applied to non-traditional domains, existing approaches for finding frequent itemsets cannot be used as they cannot model the requirement of these domains. An alternate way of modeling the objects in these data sets, is to use a graph to model the database objects. Within that model, the problem of finding frequent patterns becomes that of discovering subgraphs that occur frequently over the entire ...


Diagnosing Breast Cancer Using Protease Fingerprint JUN 2002 43 pages
Authors:  Emily I. Chen; BURNHAM INST LA JOLLA CA
The full text of this report is available for sale.The utility of using substrate phage display library to study disease-relevant metalloproteinase was further proved by identifying the selective substrates for MMP-l4 (NTl-MNP) . In addition, a different proteomic approach of achieving the original aim of identifying new diagnostic marker for breast cancer was applied and reported in this report. An activity-based probe, FP-biotin, was used to analyze the global activity pattern of a class of disease-relevant enzymes, serine hydrolases, ...


C/EBP(Beta) Isoforms - An Innovative Transcription Factor Therapy for Breast Cancer MAY 2002 27 pages
Authors:  Linda J. Sealy; VANDERBILT UNIV NASHVILLE TN
The full text of this report is available for sale.The transcription factor, C/EBPbeta, is critical for growth and differrentation of the mammary gland. Three forms of C/EBPbeta are expressed in cells through alternative translation of the C/EBPbeta mRNA. C/EBPbeta- 1 and -2 activate transcription; C/EBPbeta-2 is a truncated form that represses transcription. Based upon their distinct expression patterns in normal and transformed cells as well as functional studies, we propose that C/EBPbeta-l and -3 (or both) will be potent ...


Handling Translation Divergences in Generation-Heavy Hybrid Machine Translation MAR 2002 12 pages
Authors:  Nizar Habash; Bonnie Dorr; MARYLAND UNIV COLLEGE PARK INST FOR ADVANCED COMPUTER STUDIES
The full text of this report is available for sale.This paper describes a novel approach for handling translation divergences in a Generation- Heavy Hybrid Machine Translation (GHMT) system. The approach depends on the existence of rich target language resources such as word lexical semantics, including in- formation about categorical variations and subcategorization frames. These resources are used to generate multiple structural variations from a target-glossed lexico-syntactic representation of the source language sentence. The multiple structural variations account for different ...


Learning Domain-Specific Transfer Rules: An Experiment with Korean to English Translation 2002 8 pages
Authors:  Benoit Lavoie; Michael White; Tanya Korelsky; COGENTEX INC ITHACA NY
The full text of this report is available for sale.We describe the design of an MT system that employs transfer rules induced from parsed bitexts and present evaluation results. The system learns lexico-structural transfer rules using syntactic pattern matching, statistical co-occurrence and errordriven filtering. In an experiment with domainspecific Korean to English translation, the approach yielded substantial improvements over three baseline systems. In this paper, we describe the design of an MT system that employs transfer rules induced from ...


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