| Recreating the 1950's Chesapeake Bay: Use of a Network Model to Guide the Application of a Eutrophication Model |
Aug-2009 |
78 pages |
| Authors:
Dorothy H Tillman; Carl F Cerco; ENGINEER RESEARCH AND DEVELOPMENT CENTER VICKSBURG MS ENVIRONMENTAL LAB
|
 | This report is the last of a series that documents research relating the coupling of spatially and temporally detailed eutrophication models with ecosystem models that lack spatial and temporal resolution. Specifically, the Corps of Engineers Integrated Compartment Water Quality Model, CE-QUAL-ICM (ICM) is coupled to the Ecopath with Ecosim (EWE) fisheries model. This research examines the feasibility of restoring the ecosystem that existed in the 1950s mid Bay based on ... |
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| Physical, Nutrient, and Biological Measurements of Coastal Waters off Central California in October 2008 |
May-2009 |
83 pages |
| Authors:
Reiko Michisaki; Baldo Marinovic; Katherine Whitaker; Marguerite Blum; Thomas A Rago; NAVAL POSTGRADUATE SCHOOL MONTEREY CA
|
| The results of analyses of hydrographic, nutrient, and biological data collected in coastal ocean waters off Central California in October 2008 aboard the R/V Point Sur are presented in both tabular and graphical form. The cruise departed from and returned to Moss Landing, California. Hydrographic stations were completed along CalCOFI Line 67 to station 90, thence along CalCOFI Line 60 from station 75 shoreward to Drake's Bay. An additional 3 ... |
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| On-The-Move Nutrient Delivery System (NDS): User Acceptability of Rotary Flow Control Version |
Apr-2009 |
28 pages |
| Authors:
Scott J Montain; Susan J McGraw; Matther R Ely; Frederick Dupont; William J Tharion; ARMY RESEARCH INST OF ENVIRONMENTAL MEDICINE NATICK MA
|
| Dismounted operations make it difficult for Warriors to drink and eat enough. The Nutrient Delivery System (NDS) is an add-on to collapsible bladder with drink tube personal hydration systems, and is intended to facilitate fluid and on-the-move nutrient intake. Soldier feedback (n=83) was captured regarding acceptability of NDS form and function, and their opinions regarding the merits of the system. Sixty-eight percent of the Soldiers rated the device as moderately ... |
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| Interaction of Hurricane Katrina with Optically Complex Water in the Gulf of Mexico: Interpretation Using Satellite-Derived Inherent Optical Properties and Chlorophyll Concentration |
Apr-2009 |
6 pages |
| Authors:
Paul Lyon; James Acker; Frank Hoge; Suhung Shen; Mitchell Roffer; Greg Gawlikowski; NAVAL RESEARCH LAB STENNIS SPACE CENTER MS OCEANOGRAPHY DIV
|
| When Hurricane Katrina passed over southern Florida, Florida Bay and the West Florida Shelf, and into the Gulf of Mexico, empirically derived chl a increases were observed in the Tortugas Gyre circulation feature, and in adjacent waters. Analysis of the empirically derived chl a increase within the gyre has been primarily attributed to initiation of a phytoplankton bloom promoted by nutrients upweiled by Katrina's winds. Detailed analysis of inherent optical ... |
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| Molecular Connections Between Arousal and Metabolic Disease: Orexin and Modafinil |
Apr-2009 |
19 pages |
| Authors:
Stephen C Benoit; CINCINNATI UNIV OH
|
| Metabolic diseases are known to be tightly linked to arousal-sleep cycles and impact cognitive function. Importantly, the armed forces represent a population at significant risk for increased stress and disrupted arousal-sleep cycles. Because the incidence of metabolic disease and obesity is increasing, even in these physically fit individuals, understanding the interactions between these systems is highly significant. Further, some anti-fatigue pharmacologies (e.g.,modafinil) are already used in military settings, though their ... |
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| Characterization of Episodic Rip Current Pulsations in the Inner Shelf During RCEX 2007 |
Mar-2009 |
63 pages |
| Authors:
Andrea C O'Neill; NAVAL POSTGRADUATE SCHOOL MONTEREY CA
|
| As the Navy thrusts operations into global brown water environments, a more complete understanding of the phenomena ships and swimmers will encounter in nearshore regions is necessary. Rip currents remain infamous and important characteristics of the nearshore environment. These events not only impinge upon swimmers' safety, but may play a key role transferring water, containing nutrients, biologics, and even shore-/ship-borne pollution, between the surf zone and open ocean environments. Vertical ... |
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| Mycoleptodiscus terrestris: An Endophyte Turned Latent Pathogen of Eurasian Watermilfoil |
Mar-2009 |
7 pages |
| Authors:
Judy F Shearer; ENGINEER RESEARCH AND DEVELOPMENT CENTER VICKSBURG MS
|
| Plants that are stressed or weakened are more susceptible to disease than healthy plants. An endophytic fungus that has the capability of becoming a latent pathogen may trigger a host-fungus interaction resulting in disease development in Eurasian watermilfoil (Myriophyllum spicatum L.) (EWM) plants when they are subjected to stress. The purpose of the present study was to determine if endophyte infected (E+) plants that are weakened by nutrient stress decline ... |
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| Bio-Physical Ocean Modeling in the Gulf of Mexico |
Jan-2009 |
|
| Authors:
Sergio deRada; Stephanie Anderson; Robert A Arnone; NAVAL RESEARCH LAB STENNIS SPACE CENTER MS OCEANOGRAPHY DIV
|
 | The Naval Research Laboratory (NRL) Oceanography Division has implemented a 1/25 deg horizontal-resolution numerical ocean model for the Gulf of Mexico (GOM). The model domain encompasses the entire GOM extending from 18 deg to 31 deg North and from 77 deg to 98 deg West. The physical formulation is based on the Naval Coastal Ocean Model (NCOM) configured with a 40 level -z vertical structure: 19 terrain-following (sigma) levels at ... |
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| Physical, Nutrient, and Biological Measurements of Coastal Waters off Central California in June 2008 |
Dec-2008 |
55 pages |
| Authors:
Reiko Michisaki; Baldo Marinovic; Katherine Whitaker; Marguerite Blum; Thomas A Rago; NAVAL POSTGRADUATE SCHOOL MONTEREY CA DEPT OF OCEANOGRAPHY
|
| The results of analyses of hydrographic, nutrient, and biological data collected in coastal ocean waters off Central California in June 2008 aboard the R/V Point Sur are presented in both tabular and graphical form. The cruise departed from and returned to Monterey, California. Because the cruise encountered unusually (for the time of year) heavy weather, scientific operations could only be completed along CalCOFI line 67 from Monterey to station 75, ... |
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| Environmental Factors Affecting Aquatic Plant Growth Potential in Marinuka Lake, Wisconsin |
Dec-2008 |
14 pages |
| Authors:
William F James; ENGINEER RESEARCH AND DEVELOPMENT CENTER VICKSBURG MS
|
| Submersed aquatic macrophytes play an important role in stabilizing sediment from resuspension, sequestering nutrients, and reducing algal growth in shallow lakes. Loss of vegetation is usually accompanied by changes in stable state to one characterized by higher turbidity, low light penetration, and frequent noxious algal blooms. Aquatic vegetation once played an important role in stabilizing the sediment and providing important fish and water fowl habitat in Marinuka Lake, Wisconsin. However, ... |
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| Groundwater Chemistry and Microbial Ecology Effects on Explosives Biodegradation |
01-Sep-2008 |
217 pages |
| Authors:
Mark E Fuller; Robert J Steffan; SHAW ENVIRONMENTAL INC LAWRENCEVILLE NJ
|
| The overall goal of this project was to gain a better understanding of the microbial ecology of explosives compound biodegradation in groundwater. Deciphering which organisms are involved with explosives degradation under various in situ conditions could lead to better diagnostic and monitoring tools for bioremediation of energetics based on biomarkers, as well as lead to better conceptual and predictive models. Initially, the scope of this project included most of the ... |
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| Assessment of Composting Feasibility at Army Installations |
01-Sep-2008 |
16 pages |
| Authors:
ARMY CENTER FOR HEALTH PROMOTION AND PREVENTIVE MEDICINE ABERDEEN PROVING GROUND MD
|
| The purpose of this assessment was to evaluate various types of composting operations to determine their technical and economic feasibility at Army installations. The assessment included site visits to two installations with dissimilar compost programs. Another objective was to determine how USACHPPM could assist Army installations in developing compost programs. |
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| Direct Fixed-Bed Biological Perchlorate Destruction Demonstration |
01-Sep-2008 |
169 pages |
| Authors:
STEVEN WALKER; Xu Li; Giridhar Upadhyaya; Lutgarde Raskin; Sean Poust; Winnie Shih; Axel Ettori; Gregorio Estavo; Chance Lauderdale; Jess Brown; Eberhard Morgenroth; CAROLLO ENGINEERS WALNUT CREEK CA
|
| In February 2007, a 10-month demonstration study was initiated in Rialto, California to treat perchlorate-contaminated groundwater using fixed-bed (FXB) bioreactor technology. Two first-stage, parallel FXB bioreactors (F120 with a 3.9-ft bed depth and a 2-ft diameter, and F130 with a 4.7-ft bed depth and a 2-ft diameter) treated groundwater to remove perchlorate. Effluent from these reactors was dosed with hydrogen peroxide (i.e., reoxygenate + oxidize residual organics and hydrogen sulfide). ... |
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| On-the-Move Nutrient Delivery System Performance Characteristics |
Sep-2008 |
20 pages |
| Authors:
Scott J Montain; Matthew R Ely; Kenneth N Racicot; ARMY RESEARCH INST OF ENVIRONMENTAL MEDICINE NATICK MA
|
| Dismounted operations make it difficult for Warriors to drink and eat enough. The Nutrient Delivery System (NDS) is an add-on to collapsible bladder with drink tube personal hydration systems, and is intended to facilitate fluid and on-the-move nutrient intake. Tests were performed using an artificial sipping system and carbohydrate-beverage concentrates (CHO) to characterize NDS performance attributes. A variety of CHO formulations were also studied to define the ideal beverage concentrate ... |
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| Biodegradation of Dense Non-Aqueous Phase Liquids (DNAPL) Through Bioaugmentation of Source Areas - Dover National Test Site, Dover, Delaware |
Aug-2008 |
60 pages |
| Authors:
NAVAL FACILITIES ENGINEERING SERVICE CENTER PORT HUENEME CA
|
| The objective of the demonstration described herein was to evaluate the performance of bioaugmentation at field scale to enhance rates of biodegradation at the DNAPL: water interface, thereby increasing the concentration gradient driving DNAPL dissolution. This demonstration used PCE as the primary DNAPL in a porous media groundwater system and consisted of field and laboratory investigations. The combination of these investigations was to determine if bioaugmentation can stimulate complete dechlorination ... |
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| Physical, Nutrient, and Biological Measurements of Coastal Waters off Central California in November 2007 |
01-Jul-2008 |
79 pages |
| Authors:
Thomas A Rago; Reiko Michisaki; Baldo Marinovic; Marguerite Blum; Katherine Whitaker; NAVAL POSTGRADUATE SCHOOL MONTEREY CA DEPT OF OCEANOGRAPHY
|
| The results of analyses of hydrographic, nutrient, and biological data collected in coastal ocean waters off Central California in November 2007 aboard the NOAA Ship David Starr Jordan are presented in both tabular and graphical form. The cruise departed from and returned to San Francisco, California. After steaming to Monterey Bay, the ship proceeding from Moss Landing, California, along CalCOFI line 67 to station 90, thence to CalCOFI line 60/station ... |
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| A Search for New Therapeutic Targets: Using Yeast to Find the GEF for Rheb |
Jul-2008 |
6 pages |
| Authors:
Janet Leatherwood; STATE UNIV OF NEW YORK AT STONY BROOK RESEARCH FOUNDATION
|
| The Tsc1/2 complex known as Hamartin/Tuberin is mutated in the human disease Tuberous Sclerosis and such mutation predisposes for cancer. Tsc1/2 complex has a clearly established chemical release a GTPase Activating Protein or GAP for the small GTPase Rheb. Rheb in turn regulates TOP. The Tor kinases and associated proteins are large complex units that integrate signals pertaining to nutrients and proliferation potential. Tor promotes growth and proliferation and thus ... |
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| Regulation of Oil Biosynthesis in Algae |
25-Jun-2008 |
3 pages |
| Authors:
Christoph Benning; Eric R Moellering; Rachel Miller; Marie Fedewa; MICHIGAN STATE UNIV EAST LANSING CONTRACT AND GRANT ADMINISTRATION
|
| Many algae including Chlamydomonas accumulate triacylglycerols when cultures enter stationary phase leading to nutrient limitation. The identification of microalgal genes encoding the enzymes and regulatory factors required for the induction of oil biosynthesis is the immediate goal of the proposed work. Towards this end the following findings were met: 1.) A mutant screen to isolate gene disruption mutants of Chlamydomonas was established and 15 mutants were identified with altered lipid ... |
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| A Predictive Model for Satellite-Derived Phytoplankton Absorption Over the Louisiana Shelf Hypoxic Zone: Effects of Nutrients and Physical Forcing |
06-Jun-2008 |
18 pages |
| Authors:
Rebecca E Green; Gould; Richard W Jr; NAVAL RESEARCH LAB STENNIS SPACE CENTER MS OCEANOGRAPHY DIV
|
| We investigated environmental forcing mechanisms of phytoplankton absorption near the Mississippi River delta using multi-year satellite data. An algorithm for the phytoplankton absorption coefficient was developed from in situ measurements and applied to ocean color imagery. We employed a suite of chemical and physical forcing variables, including surface currents. For satellite-derived time series (2002-2004) correlation and stepwise regression analyses revealed the most important forcing variables on the Louisiana shelf. Mississippi ... |
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| Demonstration of GSSHA Hydrology and Sediment at Eau Galle Watershed Near Spring Valley, Wisconsin |
MAR 2008 |
20 pages |
| Authors:
ENGINEER RESEARCH AND DEVELOPMENT CENTER VICKSBURG MS
|
| The purpose of this System-Wide Water Resources Program (SWWRP) technical note is to describe the application of the Gridded Surface Subsurface Hydrologic (GSSHA) model to the analysis of the watershed upstream of Spring Valley Reservoir located near Spring Valley, WI. GSSHA was applied at this watershed to demonstrate the capability of the model to simulate the hydrology and sediment transport in the Upper Mississippi River Valley region. |
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| Layered Organization in the Coastal Ocean: Acoustical Data Acquisition, Analyses and Synthesis |
Jan-2008 |
10 pages |
| Authors:
D V Holliday; C F Greenlaw; RHODE ISLAND UNIV NARRAGANSETT GRADUATE SCHOOL OF OCEANOGRAPHY
|
| The long-term goal of our research is to improve our ability to observe the ocean's plants, animals, and their physical and chemical environment at the scales that control how they live, reproduce, and die. We are working with our colleagues in the ONR-sponsored research program on Layered Organization in the Coastal Ocean (LOCO) to jointly analyze data collected in Monterey Bay, CA during FY2002, 2005 and 2006. Our work this ... |
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| Quantifying Trophic and Demographic Rates of Plankton-Rich Layers in East Sound, Orcas Island, Washington |
Jan-2008 |
15 pages |
| Authors:
Susanne Menden-Deuer; RHODE ISLAND UNIV NARRAGANSETT GRADUATE SCHOOL OF OCEANOGRAPHY
|
| Localized concentrations of plankton (i.e. patches) alter the optical and acoustical properties of the water column and can have significant ramifications for the ecological dynamics of marine communities. The goal of this research is to develop a mechanistic understanding and predictive capability of the biological drivers of plankton patch formation, persistence and decline. This goal will be addressed by concurrent characterization of the physical, chemical and biological parameters associated with ... |
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| Quantification of the Interacting Physical, Biological, Optical and Chemical Properties of Thin Layers in the Sea |
Jan-2008 |
10 pages |
| Authors:
Margaret A McManus; Mark T Stacey; John P Ryan; HAWAII UNIV AT MANOA HONOLULU DEPT OF OCEANOGRAPHY
|
| Our long-term goal is to develop the capability to predict thin layer formation and presence in the coastal ocean. The central focus of our research is to investigate: the spatial and temporal scales of thin layers, the relationship between physical processes (from the microscale to the mesoscale) and thin layers, as well as the difference between layered structures in the nearshore and offshore environments. The overarching goal of our research ... |
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| Societal Interactions in Ovarian Cancer Metastases: A Quorum Sensing Hypothesis |
01-Nov-2007 |
28 pages |
| Authors:
Carrie Rinker-Schaeffer; CHICAGO UNIV IL
|
| It is unknown what specific biochemical and biological mechanisms control metastasis. We pursued the work proposed in this application because it is our assertion that uncovering the mechanism(s) responsible for regulating metastatic colonization in ovarian requires a fresh look from a new perspective. To this end we formulated and began to test a completely novel hypothesis: That a Quorum Sensing mechanism is involved in metastatic colonization. Quorum Sensing is a ... |
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| Biocompatible and Biomimetic Self-Assembly of Functional |
03 OCT 2007 |
21 pages |
| Authors:
Jeffrey Brinker; NEW MEXICO UNIV ALBUQUERQUE DEPT OF CHEMICAL AND NUCLEAR ENGINEERING
|
| Understand cell-directed assembly and use it to direct the formation of new bio/nano interfaces and unique cellular behaviors -Investigated the inclusion of multiple amphipathic components to control and tailor interfacial structures and functions -Created new interfaces by incorporating non-native functional proteins to yield new functionalities Extend cell-directed assembly to immobilize various cell types -Encapsulated several new cell lines, including mammalian cells, in nano-structured hosts; investigated the evolving nano-structure and bio/nano ... |
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| Harmful Algal Blooms in the Mississippi Sound and Mobile Bay: Using MODIS Aqua and In Situ Data for HABs in the Northern Gulf of Mexico |
OCT 2007 |
5 pages |
| Authors:
Dan Holiday; Gregory Carter; Richard W. Gould; Hugh MacIntyre; NAVAL RESEARCH LAB WASHINGTON DC
|
| This study investigates the use of satellite remote sensing to detect blooms and predict environmental conditions leading to the formation of HAVs in the turbid coastal waters along the Mississippi and Alabama shores. Phytoplankton populations and in situ water quality were monitored at 3 to 6 week intervals at 17 locations in Mobile Bay and the Mississippi Sound beginning in July 2005 and continuing thru June 2006 along wi concurrent ... |
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| Application of a Water Quality Model to Mississippi Sound to Evaluate Impacts of Freshwater Diversions |
SEP 2007 |
889 pages |
| Authors:
Mark S. Dortch; Mansour Zakikhani; Mark R. Noel; Sung-Chan Kim; ENGINEER RESEARCH AND DEVELOPMENT CENTER VICKSBURG MS ENVIRONMENTAL LAB
|
| This report describes the development and application of a water quality model to the Mississippi Sound region to address the impacts of various freshwater diversion alternatives. The CH3D-Sigma (sigma level vertical coordinates) model code was the hydrodynamic model that was used to provide transport fluxes for the CE-QUAL-ICM water quality model. The model domain also included Mobile Bay, the Mississippi coastal bays, Lakes Pontchartrain and Borgne, Biloxi Marsh, and part ... |
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| Comparison of Key West and Persian Gulf Seawaters |
18 JUL 2007 |
16 pages |
| Authors:
Jason S. Lee; Richard I. Ray; Brenda J. Little; NAVAL RESEARCH LAB STENNIS SPACE CENTER MS OCEANOGRAPHY DIV
|
| The experiments described in this paper demonstrate changes in the chemistries and microflora of two natural coastal seawaters collected from Key West, Florida, and the Persian Gulf as a result of storage and environmental conditions. Exposure to an anaerobic atmosphere containing a mixed gas of nitrogen, carbon dioxide, and hydrogen generated the highest microflora concentration, especially sulfate-reducing bacteria (SRB). Biotic dissolved sulfide levels were also highest in the mixed gas ... |
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| Regional Availability of Plants for Prairie Restoration |
APR 2007 |
15 pages |
| Authors:
Pamela Bailey; Chester O. Martin; ENGINEER RESEARCH AND DEVELOPMENT CENTER VICKSBURG MS
|
| This technical note identifies and describes sources for seeds and plant materials that can be used for prairie restoration and management efforts on Corps of Engineers project lands. This document is a product of the Ecosystem Management and Restoration Research Program (EMRRP) work unit titled Prairie/Grassland Ecosystems on Corps Projects. Many Corps of Engineers projects contain substantial grassland acreage (Figure 1), and there is considerable potential for Corps districts to ... |
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| Lycopene Supplementation in the Complementary Management of PSA Failure: A Randomized Placebo-Controlled Trial for Prostate Cancer Survivors |
JAN 2007 |
178 pages |
| Authors:
Flora A. Ukoli; Omer Kucuk; Jay H. Fowke; MEHARRY MEDICAL COLL NASHVILLE TN
|
| This is a hypothesis driven, double-blind, randomized, controlled Phase II clinical trial to compare the effect of daily 12-month supplementation of 30mgs lycopene as a single nutrient (Lycopene) or whole-food supplement (Lyc-O-Mato(Registered)) in control of biochemical (PSA) failure in 78 African-American prostate cancer survivors treated initially by radical prostatectomy or radiation. Fasting blood samples to measure free and total PSA, lycopene, isoprostane and essential fatty acids will be collected at ... |
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| Development of a Distributed Nutrient Sub-Model (NSM Version 1.0) for Watersheds - Kinetic Process Descriptions |
NOV 2006 |
79 pages |
| Authors:
Billy Johnson; Terry Gerald; ENGINEER RESEARCH AND DEVELOPMENT CENTER VICKSBURG MS ENVIRONMENTAL LAB
|
| Within the System-Wide Water Resources Program (SWWRP), multiple riverine, estuarine, watershed, and subsurface flow models are being modified to address issues of environmental concern. Several integration approaches are either ongoing or proposed to accomplish this task. To have a full system-wide water quality and contaminant capability in SWWRP, the different hydrologic and hydraulic engines must utilize a common water quality and contaminant approach to prevent the arbitrary partitioning of constituents. ... |
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| Engineering Bony Hybrid Organs In Vitro |
NOV 2006 |
35 pages |
| Authors:
D. J. Mooney; P. Krebsbach; J. Linderman; S. Morrison; S. Takayama; C. Y. Wang; HARVARD UNIV CAMBRIDGE MA DIV OF ENGINEERING AND APPLIED SCIENCES
|
| Hybrid bony organs containing mineralized tissue, marrow and microcirculatory compartments could provide extremely novel and life-saving biosensors and tissue replacements. Previous progress in engineering distinct elements of bone suggests this more complex goal is feasible, but the challenges of integrating these elements into a single organ remain to be addressed. We are exploiting recent advances in stem cell biology, materials sciences, and microfabrication to create complex, multi-component bony organs. Materials ... |
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| Modeling, Analysis, Simulation, and Synthesis of Biomolecular Networks |
OCT 2006 |
18 pages |
| Authors:
Harvey Ruben; Vijay Kumar; Oleg Sokolsky; PENNSYLVANIA UNIV PHILADELPHIA
|
| This project under the DARPA BIOCOMP program integrated fundamental scientific investigations in the field of molecular systems biology, algorithm development for biomolecular modeling, and open source, object based software implementation. Major accomplishments were 1) experimental gene knockout strain investigations of the V.fisheri quorum sensing system that yielded a mathematical model of its regulatory proteins, 2) a model of stringent response in E.coli and M.tuberculosis describing the role of enzyme RelMtb, ... |
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| Sediment-Tracing Technology: An Overview |
SEP 2006 |
17 pages |
| Authors:
Maureen K. Corcoran; Julie R. Kelley; ENGINEER RESEARCH AND DEVELOPMENT CENTER VICKSBURG MS
|
| The purpose of this System-Wide Water Resources Program (SWWRP) technical note is to review recent literature, current trends, and research in sediment-tracing technology. Effective watershed management can be implemented only after a thorough understanding of sediment processes in river basins. Sediment processes involve erosion, deposition, and sediment transport and, because of variability within a single watershed, are difficult to quantify. Environmental and economic problems in water bodies can result from ... |
|
| Targeting Tie2 to Increase Breast Cancer Responsiveness to Antiangiogenic Therapy |
JUN 2006 |
8 pages |
| Authors:
William Lee; PENNSYLVANIA UNIV PHILADELPHIA
|
| Antiangiogenic therapy of cancers targets tumor blood vessels to deprive malignant cells of oxygen and nutrients. Therapy of human cancers has produced poorer results than therapy of mouse tumors, a disparity that may be explained by more extensive coverage of human tumor vessels (e.g. in breast cancers) by pericytes, which may be rendering vessels more therapy-resistant. Mouse mammary tumor virus (MMTV)-induced mammary carcinomas reproduce the extensive pericyte coverage of tumor ... |
|
| Physical, Nutrient, and Biological Measurements of Coastal Waters off Central California in October 2005 |
MAY 2006 |
75 pages |
| Authors:
Thomas A. Rago; Reiko Michisaki; Baldo Marinovic; Katherine Whitaker; CALIFORNIA UNIV SANTA CRUZ CENTER FOR COASTAL MARINE STUDIES
|
| The results of analyses of hydrographic, nutrient, and biological data collected in coastal ocean waters off Central California in October 2005 aboard the R/V Point Sur are presented in both tabular and graphical form. The cruise proceeded from Moss Landing, California, to Point Reyes, California, following CalCOFI line 67 to station 90, thence to CalCOFI line 60/station 90, and finally along CalCOFI line 60. Marine mammal observations taken during the ... |
|
| Comparison of Bacillus Anthracis to the Surrogate Bacillus Atrophaeus for Spore Inactivation on a Novel Antimicrobial Fabric |
MAY 2006 |
7 pages |
| Authors:
Christopher C. Thornburg; Jon J. Calomiris; HENRY M JACKSON FOUNDATION ABERDEEN PROVING GROUND MD
|
| Military fabric amended with an antimicrobial compound may reduce the viability of biological threat agents that could be encountered in contaminated environments. Bacillus atrophaeus (formerly Baclllus sub tills var. niger) is typically employed in the evaluation of antimicrobial compounds and has been reported to be less susceptible to disinfection than Baclllus anthracis, and thus is commonly used as a surrogate whenever direct evaluation with B. anthracis may not be feasible. ... |
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| Impacts of Mechanical Macrophyte Removal Devices on Sediment Scouring in Littoral Habitats: II. Experimental Operation in the Littoral Zone of Eau Galle Reservoir, Wisconsin |
MAR 2006 |
10 pages |
| Authors:
William F. James; David I. Wright; John W. Barko; Harry L. Eakin; ENGINEER RESEARCH AND DEVELOPMENT CENTER VICKSBURG MS
|
| Research experimentally evaluated the impacts of a mechanical macrophyte removal device on changes in sediment bed elevation and water quality in the littoral zone of a shallow embayment located in Eau Galle Reservoir, Wisconsin. Mechanical macrophyte removal devices are an attractive, low-cost means of removing macrophytes in specific areas without herbicides or repeated mechanical harvesting. However, commercially available mechanical macrophyte removal devices that employ a submerged roller arm and paddle ... |
|
| Military Nutrition Research: Four Tasks to Address Personnel Readiness and Warfighter Performance |
MAR 2006 |
30 pages |
| Authors:
Donna Ryan; PENNINGTON BIOMEDICAL RESEARCH CENTER BATON ROUGE LA
|
| Pennington Biomedical Research Center (PBRC) continues a 16 year collaborative effort with the Department of Defense (DoD) in this research effort. Objectives: To assess and evaluate novel ways to sustain warfighter performance during high intensity missions at home and abroad, under specially funded cooperative agreements between the US Army Medical Research and Materiel Command (USAMRMC) and PBRC, PBRC provides high quality analytical laboratory, nutrition database and metabolic unit support for ... |
|
| Gulf of Maine Ocean Observing System |
25 JAN 2006 |
68 pages |
| Authors:
Philip Bogden; Neal Pettigrew; James Irish; Will Perrie; Collin Roesler; Andrew Thomas; David Townsend; Huijie Xue; MAINE UNIV AT ORONO
|
| Funds submitted 2001 - 2005 to implement and sustain and ocean observing system for the Gulf of Maine have resulted in the organization widely known as GoMOOS. The technical program, implemented by scientists at University of Maine, Bigelow Laboratory of Ocean Sciences, Bedford Institute of Oceanography and Woods Hole Oceanographic Institution, includes 10 buoys collecting real-time observations of the ocean and atmosphere, predictive models of waves and circulation, testing of ... |
|
| Southeast Oahu Regional Sediment Management: Identifying Sediment Pathways in the Vicinity of Wailea Point, Improved Characterization and Estimates of Sediment Sources, Pathways, and Sinks Under the System-Wide Water Resources Program (SWWRP) Volume 4 |
2006 |
19 pages |
| Authors:
Thomas D. Smith; Jessica R. Hays; CORPS OF ENGINEERS FORT SHAFTER HI HONOLULU ENGINEER DISTRICT
|
| The five work units undertaking the task of increasing the understanding and developing methodologies for estimating volumes of sediment by grain size, from different sediment sources and linking the amounts of nutrients input to the system are ongoing. The results will be forthcoming by the end of FY08. The outcome will be improved estimation of the required sediment source data input for SIAM, Gridded Surface Subsurface Hydrologic Analysis (GSSHA), ADaptive ... |
|
| Velocity and Transport Characteristics of the Louisiana-Texas Coastal Current |
01 DEC 2005 |
16 pages |
| Authors:
Ewa Jarosz; Stephen P. Murray; NAVAL RESEARCH LAB STENNIS SPACE CENTER MS OCEANOGRAPHY DIV
|
| The Louisiana-Texas Coastal Current (LTCC) is a major dynamic feature responsible for the distribution of fresh water, sediment and nutrients on the northwestern shelf of the Gulf of Mexico. Earlier studies have indicated that this current exhibits a distinct although asymmetric annual cycle during which it flows downcoast, i.e., westward along the Louisiana coast and then southward along the Texas coast in fall, winter, and spring; however, in summer, the ... |
|
| Zinc: An Essential Trace Element with Potential Benefits to Soldiers |
DEC 2005 |
6 pages |
| Authors:
James P. McClung; Angus G. Scrimgeour; ARMY RESEARCH INST OF ENVIRONMENTAL MEDICINE NATICK MA MILITARY NUTRITION DIV
|
| Zinc is a trace element known to be an essential nutrient for life. It functions as a cofactor for numerous enzymes, including those involved in DNA and RNA replication and protein synthesis. Soldiers represent a unique population faced with intense metabolic and mental demands as well as exposure to various immune challenges. Some of these factors may affect their dietary zinc requirements. Although severe zinc deficiency is unlikely to occur, ... |
|
| The Effect of Glycolytic Modulation on Prostrate Cancer |
NOV 2005 |
5 pages |
| Authors:
Robert S. DiPaola; UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY NEWARK
|
| In this proposal, we focus on, and have preliminary data to support, a novel approach targeting metabolism (by inhibition of glycolysis) to compliment ongoing clinical efforts to abrogate growth factor and apoptotic pathways in prostate cancer. The proposed clinical and laboratory studies are relevant to prostate cancer, given preliminary data demonstrating the importance of modulation of the glycolytic pathway in prostate cancer cell lines independent of activation of Akt and ... |
|
| Identification and Validation of PTEN Complex, Associated Proteins |
NOV 2005 |
18 pages |
| Authors:
Rosalia Rabinovsky; DANA-FARBER CANCER INST BOSTON MA
|
| The PTEN/MMAC1/TEP1 is a tumor suppressor gene, targeted for biallelic somatic inactivation in a variety of cancers including advanced prostate adenocarcinomas among many others malignancies. PTEN is a phosphatase and has an important role in regulation of the PI3K/AKT signaling pathway, which plays a key role in regulating cellular functions including proliferation, apoptosis, glucose homeostasis, cell size, nutrient response and DNA damage. Furthermore, PTEN functions in the cell to restrict ... |
|
| The Effect of Glycolytic Modulation on Prostate Cancer |
NOV 2005 |
5 pages |
| Authors:
Robert S. DiPaola; UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY NEWARK
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| In this proposal, we focus on, and have preliminary data to support, a novel approach targeting metabolism (by inhibition of glycolysis) to compliment ongoing clinical efforts to abrogate growth factor and apoptotic pathways in prostate cancer. The proposed clinical and laboratory studies are relevant to prostate cancer, given preliminary data demonstrating the importance of modulation of the glycolytic pathway in prostate cancer cell lines independent of activation of Akt and ... |
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| Simulations of Chemotaxis and Random Motility in Finite Domains |
13 JUL 2005 |
12 pages |
| Authors:
Ehsan Jabbarzadeh; Cameron F. Abrams; DREXEL UNIV PHILADELPHIA PA
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| Rational design and selection of candidate porous biomaterials to serve as tissue engineering constructs rests on our ability to understand the influence of the porous microarchitecture on the transport of chemical species (e.g., nutrients and signaling compounds), fluid flow, and cellular locomotion and growth. We have begun to study the behavior of chemotactically mobile cells in response to unsteady signaling molecule concentration fields using a computational simulation-based model. The model ... |
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| Novel Angiogenic Compounds for Targeted Drug Delivery |
13 JUL 2005 |
5 pages |
| Authors:
Kristen A. Wieghaus; Scott M. Capitosti; Milton L. Brown; Edward A. Botchwey; VIRGINIA UNIV CHARLOTTESVILLE DEPT OF CHEMISTRY
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| Induction of angiogenesis is necessary for the success of engineered implantable tissues in order to meet oxygen and nutrient requirements of cells during tissue repair. Insufficient vascularization in bone graft reconstruction may impede healing and initiate hypoxic cell death at the interior of the implant. As a result, endogenous growth factors have been studied to enhance angiogenesis during wound repair. However, these peptide-based molecules are highly sensitive to processing that ... |
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| Targeting Tie2 to Increase Breast Cancer Responsiveness to Antiangiogenic Therapy |
JUN 2005 |
6 pages |
| Authors:
William M. Lee; PENNSYLVANIA UNIV PHILADELPHIA
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| Antiangiogenic therapy of cancers involves inhibiting tumor blood vessel development to deprive tumors of vital oxygen and nutrients. The potential benefits of antiangiogenic strategies have been dramatically shown in mouse tumor models. Results in human clinical trials, however, have been less striking. Recent trials have shown survival benefits, but tumor regression, which is often reported in murine tumors, is rarely seen in treated human cancers. A potential explanation for this ... |
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| Functional Analysis of the Beclin-1 Tumor Suppressor Interaction with hVpa34 (Type III PI3' -kinase) in Breast Cancer Cells |
JUN 2005 |
99 pages |
| Authors:
William A. Maltese; MEDICAL COLL OF OHIO AT TOLEDO
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| Macroautophagy plays a pivotal role in type II programmed cell death. This form of cell death entails early accumulation of autophagic vacuoles. Beclin 1 has been implicated in the regulation of macroautophagy. Previous reports indicate that overexpression of Beclin can promote autophagy and inhibit tumorigenesis in cultured breast carcinoma cells, and conversely, that heterozygous disruption of the Beclin gene can promote tumorigenesis in mice. During the first year we have ... |
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