| Energy Losses in Simulated Relativistic Michigan A6 Magnetron with Shaped Cathode |
Apr-2008 |
2 pages |
| Authors:
Peter Mardahl; AIR FORCE RESEARCH LAB KIRTLAND AFB NM DIRECTED ENERGY DIRECTORATE
|
 | Recently there has been much research interest in improving magnetron performance by employing various priming techniques, such as shaped cathodes and nonuniform magnetic fields. These priming techniques have been successfully applied to reduce magnetron noise and improve mode-locking and efficiency. Inserting a shaped cathode into the simulated Michigan magnetron yields a maximum efficiency (the radiofrequency (RF) output power for a cycle divided by the current times voltage input for that ... |
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| Detection of Nuclear Explosions Using Infrasound Techniques |
01 DEC 2007 |
78 pages |
| Authors:
D. R. Christie; B. L. Kennett; AUSTRALIAN NATIONAL UNIV CANBERRA RESEARCH SCHOOL OF EARTH SCIENCES
|
| The performance of typical IMS infrasound monitoring stations has been examined in detail in order to evaluate the detection capability of the global network for regional and distant nuclear explosions. Three significant problems have been identified: a) problems with the loss of higher frequency signal components in the primary monitoring passband, b) detection problems associated with a low degree of signal coherence between array elements and c) problems with high ... |
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| Adaptive Deblurring of Noisy Images |
OCT 2007 |
30 pages |
| Authors:
S. S. Young; RONALD G. DRIGGERS; Brian P. Teaney; Eddie L. Jacobs; ARMY RESEARCH LAB ADELPHI MD SENSORS SIGNATURES AND SIGNAL PROCESSING INFORMATION DIRECTORATE
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| This report proposes a practical sensor deblur filtering method for images that are contaminated with noise. A sensor blurring function is usually modeled via a Gaussian-like function having a bell shape. The straightforward inverse function results in magnification of noise at the high frequencies. In order to address this issue, we apply a special spectral window to the inverse blurring function. This special window is called the power window, which ... |
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| Environmentally Induced Gene Silencing in Breast Cancer |
JUL 2007 |
8 pages |
| Authors:
Mitchell Turker; OREGON HEALTH SCIENCES UNIV PORTLAND
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| The main goal of the study was to test the hypothesis that a reduction in gene expression (i.e. gene repression) could induce gene silencing (i.e. relatively stable loss of gene expression) in breast cells. Silencing of a variety of tumor suppressor genes plays a major role in the initiation and progression of breast cancer and our ultimate goal is to determine if environmentally induced gene repression plays a role as ... |
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| Epigenetic Silencing and Resistance to Imatinib Mesylate in CML |
JUL 2007 |
8 pages |
| Authors:
Jean-Pierre Issa; M D ANDERSON CANCER CENTER HOUSTON TX
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| We performed analyses of DNA methylation data reported in the final report with clinical outcome of CML patients. DNA methylation significantly correlated with survival. CML patients with average methylation zscore values above zero had significantly shorter survival than patients with z-scores below zero (median 10 months vs 59 months, P |
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| Functional Geonic Analysis of Breast Cancer Cell Tumorigenicity Using a Noval Gene Silencing Resource |
APR 2007 |
19 pages |
| Authors:
Douglas S. Conklin; STATE UNIV OF NEW YORK AT ALBANY RESEARCH FOUNDATION
|
| We have identified approximately 30 genes that negatively impact the growth of Erb-B2 positive breast cancer cells. Year 2 of funding resulted in tests of the specificity of the shRNAs negative impact on the growth of Erb-B2 positive breast cancer cells. Effects of these shRNAs on normal cells and other breast cancer cell lines, identified approximately 20 shRNAs that specifically inhibit Erb-B2 positive breast cancer cells target genes. Several of ... |
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| Cramer-Rao Lower Bound for Support-Constrained and Pixel-Based Multi-Frame Blind Deconvolution (Postprint) |
01 SEP 2006 |
12 pages |
| Authors:
Charles Matson; Aiim Haji; AIR FORCE RESEARCH LAB KIRTLAND AFB NM DIRECTED ENERGY DIRECTORATE
|
| Multi-frame blind deconvolution (MFBD) algorithms can be used to reconstruct a single high-resolution image of an object from one or more measurement frames of that are blurred and noisy realizations of that object. The blind nature of MFBD algorithms permits the reconstruction process to proceed without having separate measurements of knowledge of the blurring functions in each of the measurement frames. This is accomplished by estimating the object common to ... |
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| Sound Attenuation from Earmuffs and Earplugs in Combination: Maximum Benefits vs. Missed Information |
Sep-2006 |
7 pages |
| Authors:
Patricia Odell; Sharon M Abel; DEFENCE RESEARCH AND DEVELOPMENT TORONTO (ONTARIO) JUDGEMENT AND DECISION-MAKING GROUP
|
| High noise levels from aircraft, small and large caliber weapons, land vehicles, ships, or submarines are characteristic of military operational environments. Continuous levels in the interior of fixed or rotary wing aircraft or in the vicinity of jet engines range from 100 - 130 dBA (15,18). Peak sound pressure levels from impulse noise produced by a howitzer may be as high as 180 dB SPL (28). Small caliber weapons such ... |
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| Multisensory Integration for Pilot Spatial Orientation |
SEP 2006 |
162 pages |
| Authors:
Ronald L. Small; John W. Keller; Christopher D. Wickens; Connie M. Socash; Ann M. Ronan; Alia M. Fisher; MICRO ANALYSIS AND DESIGN BOULDER CO
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| This program modeled pilot spatial disorientation illusions as part of a real-time illusion detection and aiding system. The models and detection algorithms focus on human vestibular responses to aircraft motion. The aiding portion of the product was part of a comprehensive approach to combating the adverse effects of SD on military and civilian pilots. Four experiments supported the detection and aiding calculations. Two focused on creating vestibular illusions and quantifying ... |
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| Standardization of the 3-(4,5-Dimethylthiazol-2-yl)-5-(3-Carboxymethoxyphenyl)-2-(4-Sulfophenyl)-2H-Tetrazolium, Inner Salt (MTS) Assay for the SK-N-SH, KYSE-30, MCF-7, and HeLa Cell Lines |
JUL 2006 |
17 pages |
| Authors:
Jennifer G. Catalano; James J. Valdes; Darrel Menking; Kyle Hubbard; Averell L. Gnatt; MARYLAND UNIV BALTIMORE
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| One common way to examine toxicity in vitro is to measure the effect on cell viability. In one such assay, the 3-(4,5- dimethylthiazol-2-yl)-5-(3 -carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium, inner salt MTS reagent is bioreduced to a formazan product in living cells. Various cell lines may have differing abilities to reduce MTS; therefore, standardization should be carried out for each one. To optimize the assay, the toxicity of MTS, the linear range for signal versus ... |
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| PAVAD B Design and Experimental Results Report |
30 JUN 2006 |
23 pages |
| Authors:
peter C. Herdic; Brian H. Houston; Robert D. Corsaro; NAVAL RESEARCH LAB WASHINGTON DC PHYSICAL ACOUSTICS BRANCH
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| The application and experimental results are presented for the Passive and Advanced Vibro-Acoustic Treatments Demonstration, Part B (PAVAD-B) conducted at the Laboratory for Structural Acoustics, Naval Research Laboratory (NRL) during the winter and spring of 2001-2002. The goal of this demonstration is to utilize the most advanced treatments developed in the first part of the program (PAVAD-A), improve their design, and apply them to the Sponsor Supplied Structure. In the ... |
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| Development of Composite Materials with High Passive Damping Properties |
15 MAY 2006 |
129 pages |
| Authors:
Malcolm J. Crocker; AUBURN UNIV AL DEPT OF MECHANICAL ENGINEERING
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| In applications where the use of lightweight structures is important, the introduction of a viscoelastic core layer, which has high inherent damping, between two face sheets, can produce a sandwich structure with high damping. Composite sandwich structures have several advantages, such as their high strength-to-weight ratio, excellent thermal insulation, and good performance as water and vapor barriers. So in recent years, such structures have become used increasingly in transportation vehicles. ... |
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| Adjoint-based Aeroacoustic Control |
MAY 2006 |
54 pages |
| Authors:
Jonathan B. Freund; Randall R. Kleinman; Mingjun Wei; ILLINOIS UNIV AT URBANA DEPT OF THEORETICAL AND APPLIED MECHANICS
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| A technique for controlling complex unsteady high-speed flows is being developed. Our approach uses numerical solutions of the adjoint of the compressible flow equations to circumvent the complexity of the flow and directly determine the sensitivity of a specified control objective to changes in actuation. Since this method requires a complete physical description of a turbulent flow which is only currently available from direct numerical simulations, the immediate objective obviously ... |
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| Low Noise Simultaneous Fluorescence Detection of Two Atomic States (PREPRINT) |
05 APR 2006 |
5 pages |
| Authors:
M. T. Cashen; J. B. Fixler; G. W. Biedermann; M. A. Kasevich; STANFORD UNIV CA DEPT OF PHYSICS
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| We have demonstrated a new technique for fluorescence detection of ultracold atoms. Fluorescence from two spatially separated clouds of ultracold atoms illuminated by a mutual probe laser was imaged onto opposite quadrants of a position-sensitive detector. The populations in the two separated atomic clouds were measured by integrating the quadrant detector photocurrents. Simultaneous detection of the populations of the two atomic clouds was used to reduce noise caused by fluctuations ... |
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| Dietary Genistein and Prostate Cancer Chemoprevention |
APR 2006 |
11 pages |
| Authors:
Coral A. Lamartiniere; ALABAMA UNIV IN BIRMINGHAM
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| The goal of our research was to determine if there is a developmental window for suppressing prostate cancer with the phytoestrogen genistein and its mechanism (s) of chemoprevention. Life-time (starting at birth) exposure to genistein was more effective in suppressing chemically-induced prostate cancer in rats than neonatallprepubertal or adult only exposures to genistein. Neonatallprepubertal genistein exposure did not alter prostate bud development. Dietary genistein during the neonatallprepubertal period as well ... |
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| The General Image Quality Equation and the Structure of the Modulation Transfer Function |
30 MAR 2006 |
15 pages |
| Authors:
Robert B. Hindsley; Lee J. Rickard; NAVAL RESEARCH LAB WASHINGTON DC
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| Sparse aperture systems, despite their promise of lower weight or larger size, produce images that are noisier and more blurred when compared to images produced by a full aperture. Previous work by Hindsley and Mozurkewich (2001) showed that analysis of the Modulation Transfer Function (MTF) demonstrated the proportionality of signal-to-noise in a sparse aperture to the fill factor of the aperture. Analysis of the MTF also could enumerate the noise ... |
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| Doppler Aliasing Reduction in Wide-Angle Synthetic Aperture Radar Using Phase Modulated Random Stepped-Frequency Waveforms |
MAR 2006 |
79 pages |
| Authors:
Andrew W. Hyatt; AIR FORCE INST OF TECH WRIGHT-PATTERSON AFB OH DEPT OF ELECTRICAL AND COMPUTER ENGINEERING
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| This research investigates the benefits of using several phase modulated Random Stepped Frequency (RSF) waveforms in a Wide-Angle Synthetic Aperture Radar (WA-SAR) scenario. RSF waveforms have been demonstrated to have desirable properties which allow for cancelling of Doppler aliased scatterers in WA-SAR images. Additional aliased energy reduction is realized by improving the uniformity of the frequency coverage across the waveform?s bandwidth. Phase code modulations applied to the subpulses of a ... |
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| An Analysis of USAF Aircraft Noise and Hedonic Property Values |
MAR 2006 |
81 pages |
| Authors:
Melissa R. Johnson; AIR FORCE INST OF TECH WRIGHT-PATTERSON AFB OH SCHOOL OF ENGINEERING AND MANAGEMENT
|
| The primary purpose of the research was to evaluate whether there was a significant difference in housing values of those affected by the noise of USAF aircraft. The secondary purpose was to evaluate whether there was a significant difference in housing values located near USAF bases with and without aircraft noise and to evaluate whether type of aircraft changed the results created by the aircraft noise. This research effort found ... |
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| Enhanced Night Vision Via a Combination of Poisson Interpolation and Machine Learning |
FEB 2006 |
119 pages |
| Authors:
Leonard McMillan; Wei Wang; NORTH CAROLINA UNIV AT CHAPEL HILL DEPT OF COMPUTER SCIENCE
|
| Our research initiative focuses on enhancing semiconductor-based night-vision imagery via The fundamental problems of imaging under low-light conditions are noise suppression, overcoming low image contrast, and the loss of important perceptual cues. We have developed three new image-processing techniques to address these problems. These include non-linear spatio-temporal denoising filters, variants of Poisson integration for localizedcontrast adjustment, and machine-learning methods for reintroducing perceptual cues. The goal of our work is to ... |
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| Gaussian Mixture Reduction for Bayesian Target Tracking in Clutter |
22 DEC 2005 |
190 pages |
| Authors:
David J. Petrucci; AIR FORCE INST OF TECH WRIGHT-PATTERSON AFB OH SCHOOL OF ENGINEERING AND MANAGEMENT
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| The Bayesian solution for tracking a target in clutter results naturally in a target state Gaussian mixture probability density function (pdf) which is a sum of weighted Gaussian pdf's, or mixture components. As new tracking measurements are received, the number of mixture components increases without bound, and eventually a reduced-component approximation of the original Gaussian mixture pdf is necessary to evaluate the target state pdf efficiently while maintaining good tracking ... |
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| Comparison of Hyperspectral Imagery Target Detection Algorithm Chains |
14 OCT 2005 |
129 pages |
| Authors:
David C. Grimm; ROCHESTER INST OF TECH NY CHESTER F CARLSON CENTER FOR IMAGING SCIENCE
|
| Detection of a known target in an image has several different approaches. The complexity and number of steps involved in the target detection process makes a comparison of the different possible algorithm chains desirable. Of the different steps involved, some have a more significant impact than others on the final result - the ability to find a target in an image. These more important steps often include atmospheric compensation, noise ... |
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| Optically Driven Wireless Earplug for Communications and Hearing Protection |
OCT 2005 |
8 pages |
| Authors:
Jeffrey Buchholz; Toby Klusmeyer; James Janousek; James Wilt; MICRO-OPTICS TECHNOLOGIES INC MIDDLETON WI
|
| Electronic earplugs with embedded receivers provide for quality communications capability and effective double hearing protection in high noise environments. With the addition of ear canal microphones in the earplug greater hearing protection can be achieved using active noise reduction (ANR) in the ear canal. Current communication earplugs must be connected by wire to the outside world or must carry an onboard power source. The wire connection makes don and doff ... |
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| Sparse Data Representation: The Role of Redundancy in Data Processing |
13 SEP 2005 |
21 pages |
| Authors:
Eitan Tadmor; MARYLAND UNIV COLLEGE PARK
|
| The last decade has seen a dramatic increase in computational power and sensor ubiquity, as well as an ever increasing demand for finer resolution in both scientific and geometric modeling. This has led to the creation of enormously large data sets with exquisite detail. However, these data sets will be useful only if we can process them efficiently, whether it be for storage, transmission, visual display, fast on-line graphical query, ... |
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| Passive Hearing Protection Systems and Their Performance |
01 JUN 2005 |
|
| Authors:
Richard McKinley; Valerie Bjorn; AIR FORCE RESEARCH LAB WRIGHT-PATTERSON AFB OH
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 | While ideally noise should be reduced at the source, in the military environment the most effective solution in terms of both cost and operational effectiveness has been to provide personnel with personal hearing protection. This protection may be in the form of either an earplug that occludes the ear canal or a circumaural protector that inserts a barrier between the ambient noise and the ear. For both devices the level ... |
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| Functional Analysis of the Beclin-1 Tumor Suppressor Interaction with hVpa34 (Type III PI3' -kinase) in Breast Cancer Cells |
JUN 2005 |
99 pages |
| Authors:
William A. Maltese; MEDICAL COLL OF OHIO AT TOLEDO
|
| Macroautophagy plays a pivotal role in type II programmed cell death. This form of cell death entails early accumulation of autophagic vacuoles. Beclin 1 has been implicated in the regulation of macroautophagy. Previous reports indicate that overexpression of Beclin can promote autophagy and inhibit tumorigenesis in cultured breast carcinoma cells, and conversely, that heterozygous disruption of the Beclin gene can promote tumorigenesis in mice. During the first year we have ... |
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| Personal Hearing Protection including Active Noise Reduction (Les dispositifs de protection de l'ouie, y compris l'attenuation du bruit actif) (CD-ROM) |
JUN 2005 |
|
| Authors:
H. J. Steeneken; A. Dancer; R. McKinley; K. Buck; S. James; NATO RESEARCH AND TECHNOLOGY ORGANIZATION NEUILLY-SUR-SEINE (FRANCE)
|
| ELECTRONIC FILE CHARACTERISTICS: 43 files; Adobe Acrobat (.PDF) and HTML. PHYSICAL DESCRIPTION: 1 CD-ROM; 4 3/4 in.; 212 MB. SYSTEMS DETAIL NOTE: Adobe Acrobat Reader is included on disc. ABSTRACT: Personal hearing protection and speech communication facilities are essential for optimal performance in military operations. High noise levels increase the risk of noise induced hearing loss and deterioration of communications. These proceedings from a lecture series on hearing protection and ... |
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| A Hybrid Electrochemical Energy Source |
05 MAY 2005 |
13 pages |
| Authors:
Charles J. Patrissi; Eric G. Dow; Maria M. Medeiros; DEPARTMENT OF THE NAVY WASHINGTON DC
|
| It is a general purpose and objective of the present invention to establish an electrochemical energy source for use in an underwater environment that utilizes the hydrogen byproduct of a lithium anode battery, such as the lithium water battery, and by doing so increases the coulombic efficiency of the lithium anode battery and eliminates the noise associated with venting the hydrogen, resulting in a quiet operation energy source with high ... |
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| Creating a Culture of Patient Safety through Innovative Hospital Design |
MAY 2005 |
16 pages |
| Authors:
John G. Reiling; AGENCY FOR HEALTHCARE RESEARCH AND QUALITY ROCKVILLE MD
|
| When SynergyHealth, St. Joseph's Hospital of West Bend, Wisconsin, decided to relocate and build an 82-bed acute care facility, they recognized the opportunity to design a hospital that focused on patient safety. Hospital leaders believed that if a facility design process was "engineered properly," it would enhance patient safety and create a patient safe culture. Unfortunately, the planners found little information to give them direction. To help them plan the ... |
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| Control of Acoustics and Store Separation in a Cavity in Supersonic Flow |
FEB 2005 |
141 pages |
| Authors:
Debashis Sahoo; MASSACHUSETTS INST OF TECH CAMBRIDGE DEPT OF AERONAUTICS AND ASTRONAUTICS
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| The supersonic flight community is currently faced with two cavity-under-cross-flow related problems, one being the high noise levels inside the cavity and the other being the return of a store into the cavity after being released from inside. This thesis provides a systematic framework to understand the dominant physics in both problems and to provide solutions for ameliorating the problems. For the first problem, an innovative cavity acoustics model is ... |
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| Boiling Heat Transfer Surface |
05 JAN 2005 |
12 pages |
| Authors:
Robert Kuklinski; DEPARTMENT OF THE NAVY WASHINGTON DC
|
| This patent application relates to a system for a vehicle that creates and maintains a gas/vapor cavity to reduce drag and increase propulsion efficiency. The gas/vapor cavity also can be used to reduce noise received by a sonar system. The system to create and maintain a gas/vapor cavity about a hull surface includes a fence selectively extendable above and below the hull surface. A gas venting means is positioned beneath ... |
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| Boiling Heat Transfer Torpedo |
05 JAN 2005 |
22 pages |
| Authors:
Robert Kuklinski; DEPARTMENT OF THE NAVY WASHINGTON DC
|
| This patent application discloses a system for a torpedo that creates and maintains a vapor cavity to reduce drag and increase propulsion efficiency. The system has a source of gas venting gas at a nose portion of the vehicle to create a gas/vapor cavity on the nose portion and an adjacent hull of the vehicle. A thermal engine propelling the vehicle through ambient water creates waste heat for heating the ... |
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| AFRL/NASA Shaped Sonic Boom Experiment Flight Test Program. Delivery Order 0021: Origins and Overview of the Shaped Sonic Boom Demonstration Program |
JAN 2005 |
41 pages |
| Authors:
Joseph W. Pawlowski; David H. Graham; Charles H. Boccadoro; Peter G. Coen; Domenic J. Maglieri; NORTHROP GRUMMAN CORP EL SEGUNDO CA INTEGRATED SYSTEMS
|
| The goal of the DARPA Shaped Sonic Boom Demonstration (SSBD) Program was to demonstrate for the first time in flight that sonic booms can be substantially reduced by incorporating specialized aircraft shaping techniques. Although mitigation of the sonic boom via specialized shaping techniques was theorized decades ago, until now this theory had never been tested with a flight vehicle subjected to actual flight conditions in a real atmosphere. The demonstrative ... |
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| Protein BioChip Mass Spectrometry: A Novel Protein Profiling Approach for Diagnosis and Prognosis of Prostate Cancer |
JAN 2005 |
16 pages |
| Authors:
Bao-Ling Adam; MEDICAL COLL OF GEORGIA AUGUSTA RESEARCH INST
|
| The present study was designed for the early detection of prostate cancer and monitoring the outcome of prostatectomy treatment. All the prostate cancer patients had undergone radical prostatectomy with no positive nodes, no extra capsular extension, no positive seminal vesicle involvement at time of surgery, and no positive CT scans post surgery. This allowed us to build a pattern matching algorithm to detect early stage cancer. Currently, we are developing ... |
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| Separation of Speech from Background |
15 DEC 2004 |
13 pages |
| Authors:
John Josephson; James Russell; AETION TECHNOLOGIES LLC COLUMBUS OH
|
| Phase I has resulted in advances in computational methods, assessments of current strengths and weakness, and assessments of the range of potential applications and their performance requirements. The progress and results from Phase I show that the technology is very promising. However, it has also become clear that the problem is quite challenging, and significant technical weaknesses remain. Phase II would aim to overcome the most significant weaknesses preventing practical ... |
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| Principal Components Based Techniques for Hyperspectral Image Data |
DEC 2004 |
103 pages |
| Authors:
Leonidas Fountanas; NAVAL POSTGRADUATE SCHOOL MONTEREY CA
|
| PC and MNF transforms are two widely used methods that are utilized for various applications such as dimensionality reduction, data compression and noise reduction. In this thesis, an in-depth study of these two methods is conducted in order to estimate their performance in hyperspectral imagery. First the PCA and MNF methods are examined for their effectiveness in image enhancement. Also, the various methods are studied to evaluate their ability to ... |
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| Wearable Sparse-Conformal-Acoustic-Networks for Tracking and ID of Urban Targets (CD-ROM) |
17 NOV 2004 |
|
| Authors:
Bernard Widrow; Victor Eliashberg; CARDINAL RESEARCH LLC STANFORD CA
|
| ELECTRONIC FILE CHARACTERISTICS: 72 files; Adobe Acrobat (.PDF), MS Word (.DOC), and Winamp media file (.WAV). PHYSICAL DESCRIPTION: 1 CD-ROM; 4 3/4 in.; 14 MB. SYSTEMS DETAIL NOTE: ABSTRACT: The objective of the research is the development of wearable acoustic array technology to enable a wirelessly connected squad of soldiers in an urban battle field to detect, localize, track, and categorize acoustic target signals. For the individual soldiers, sensitive ... |
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| Anisotropic Diffusion Despeckling for High Resolution SAR Images |
NOV 2004 |
7 pages |
| Authors:
Chen Xi; Wang Chao; Zhang Hong; Tang Yixian; BEIJING NORMAL UNIV (CHINA)
|
| The main purpose of this work is to perform a new denoising method based on a nonlinear anisotropic diffusion for the reducing of the multiplicative speckle in high resolution Synthetic Aperture Radar (SAR) images. In order to be applicable to the sampled data and reduce computing complexity, an efficient discretization scheme, e.g. additive operator splitting (AOS) scheme, is chosen here for the proposed approach. Examples are given comparing the new ... |
|
| Technical Evaluation Report |
OCT 2004 |
5 pages |
| Authors:
Yvan Baudoin; ROYAL MILITARY ACADEMY BRUSSELS (BELGIUM) DEPT OF APPLIED MECHANICS
|
| The requirements for performant military vehicles are often limited to three important parameters: the mobility (manoeuvrability performances) , the survivabilty (protection of the vehicle) and the lethality (weapon systems) . The habitability, as it has been defined during this first symposium devoted to driving safety and the ride comfort of the Military Operators, is even often considered as secondary, with, as consequence, a real degradation of the Human performances. But ... |
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| Optically Driven Wireless Earplug for Communications and Hearing Protection |
SEP 2004 |
8 pages |
| Authors:
Jeffrey Buchholz; Toby Klusmeyer; James Janousek; James Wilt; MICRO-OPTICS TECHNOLOGIES INC MIDDLETON WI
|
| The objective of this work was to develop a wireless link to active electronic earplugs used for communication and active noise reduction for hearing protection in high noise environments. The wireless link was designed to be a local link to the individuals hearing protection or communications earmuff in a double hearing protection situation. The wireless link is to replace the wired link needed for other active earplug implementations so as ... |
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| Characterization of Dislocation Core Structures in BCC Metals |
30 AUG 2004 |
17 pages |
| Authors:
Kevin J. Hemker; JOHNS HOPKINS UNIV BALTIMORE MD DEPT OF MECHANICAL ENGINEERING
|
| The scientific aim of this study was to use state-of-the-art TEM techniques to experimentally describe dislocation core structures in bcc metals through experimental characterization of screw dislocations in single-crystalline Mo. Methods were developed for deriving localized electron structure data from electron energy loss spectra (EELS) taken from perfect lattice regions and along dislocations and low angle boundaries in ordered NiAl. Significant changes in the fine structure of the NiL edge ... |
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| Adaptive Filtering in the Wavelet Transform Domain via Genetic Algorithms |
06 AUG 2004 |
46 pages |
| Authors:
Pat Marshall; Frank Moore; Eric Balster; AIR FORCE RESEARCH LAB WRIGHT-PATTERSON AFB OH INFORMATION DIRECTORATE
|
| This paper primarily addresses the problem of quantization noise since it is one of the very few processes that potentially eliminates valuable signal information. In a lossy compression system, the quantization step is totally responsible for information loss resulting is quality reduction of the reconstructed signal. For this effort, adaptive filtering techniques are utilized for modifying standard, off-the-shelf, discrete wavelet transform (DWT) coefficients in the hopes that the differential errors ... |
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| Role of Carcinoembryonic Antigen (CEA) in Breast Cancer |
AUG 2004 |
16 pages |
| Authors:
Rajesh K. Gaur; CITY OF HOPE BECKMAN RESEARCH INST DUARTE CA
|
| Carcinoembryonic antigen (CEA) is a highly glycosylated protein that is overexpressed in many human cancers including, breast cancer. Recent studies suggest that overexpression of CEA promotes tumorogenesis by inhibiting cell differentiation, and by preventing anoikis, a type of apoptotic program which destroys cells that lose contact with the extacellular matrix. If arid how CEA promotes breast cancer remains to be determined. Our hypothesis is that if overexpression of CEA is ... |
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| A Performance On-Demand Approach to Power-Efficient Computing |
14 JUL 2004 |
20 pages |
| Authors:
David H. Albonesi; Sandhya Dwarkadas; Eby G. Friedman; Michael L. Scott; ROCHESTER UNIV NY
|
| Complexity-Adaptive Processing (CAP) addresses increasing microprocessor power dissipation through on-the-fly, low-cost hardware adaptation and related circuit techniques so as to better match hardware complexity and speed to application demands. Specific results include adaptive processing elements and hardware/software control techniques, a Multiple Clock Domain processor that saves energy via fine-grain voltage scaling, power- efficient issue queue and register file techniques, a low-leakage dynamic logic circuit and associated control logic for functional ... |
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| Using RNA Interference to Reveal Genetic Vulnerabilities in Human Cancer Cells |
JUL 2004 |
28 pages |
| Authors:
Despina Siolas; Gregory J. Hannon; COLD SPRING HARBOR LAB NY
|
| Many eukaryotic organisms respond to double stranded RNA (dsRNA) by initiating a sequence specific silencing pathway known as RNA intereference or RNAi. The ability to exploit RNAi as an experimental tool for cancer has evolved in lock-step with an elucidation of the underlying biochemical mechanism of this regulatory pathway. Due in part to the triggering of non-sequence specific responses by dsRNAs of greater than 30-50 nucleotides, the experimental use of ... |
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| Fermi Electronics: A Means of Correlating and Canceling Shot Noise From Solid State Devices |
08 JUN 2004 |
48 pages |
| Authors:
Elliot R. Brown; CALIFORNIA UNIV LOS ANGELES
|
| This project has developed a formalism for computing the shot noise in resonant- tunneling structures having an arbitrary number of quantum wells. It is based on the electrostatic feedback effect in quantum-well structures and is the first known shot noise formalism that treats the electrostatic and quantum effects in a self-consistent fashion. Simulation results are analyzed and compared to experimental results for an InGaAs/AlAs double-barrier structure, which is the fastest ... |
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| Coupled Dynamic Systems and Le Chatelier's Principle in Noise Control |
JUN 2004 |
28 pages |
| Authors:
G. Maidanik; K. J. Becker; NAVAL SURFACE WARFARE CENTER CARDEROCK DIV BETHESDA MD SIGNATURES DIRECTORATE
|
| Investigation of coupling an adjunct dynamic system to an externally driven dynamic system - a master dynamic system - reveals that the response of the adjunct dynamic system affects the pre-coupled response of the master dynamic system. The responses, in the two dynamic systems when coupled, are estimated by the stored energies and, respectively. Since the adjunct dynamic system, prior to coupling was with zero stored energy, the pre-coupled stored ... |
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| Construction and Testing of Compact Low-Noise Hydrophones with Extended Frequency Response |
JUN 2004 |
|
| Authors:
Konstantinos Bakas; NAVAL POSTGRADUATE SCHOOL MONTEREY CA
|
| A simple, low-noise hydrophone design with internal preamplifier is presented. This design is similar to published designs and is a variation of the design developed in the Naval Postgraduate School thesis by Miguel Alvarado in 2003, except that several features have been improved. These include a simplification of the structure and its modes of vibration, a large reduction in package diameter and the effect its acoustic diffraction has on sensitivity, ... |
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| Telomere Length and Genomic Stability as Indicators of Breast Cancer Risk |
MAY 2004 |
23 pages |
| Authors:
Ying Zou; TEXAS UNIV SOUTHWESTERN MEDICAL SCHOOL AT DALLAS
|
| Telomeres are repetitive sequences that protect the ends of linear chromosomes and shorten during each cell division. Very short telomeres have been associated with changes in gene expression (in yeast) and decreased genome stability. We published the first proof that silencing effects can occur at human telomeres. A luciferase reporter near a telomere showed on average a 10- fold reduction in expression relative to internal control genes. The silencing is ... |
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| Vortex-Assisted Pressure Control at Inlet of Underwater Launch System |
21 APR 2004 |
14 pages |
| Authors:
Thomas J. Gieseke; DEPARTMENT OF THE NAVY WASHINGTON DC
|
| The present invention relates generally to controlling the flow of a surrounding environmental fluid into an inlet formed in a moving vehicle, and more particularly to a system that uses vortices to control such a flow at the inlet of, for example, an underwater vehicle's underwater launch system. Many underwater launch systems used by underwater vehicles utilize the forward motion of the vehicle and underwater pressure to develop a dynamic ... |
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| Genetic and Epigenetic Silencing of the AS3 Proliferative Arrest Gene in Prostate Cancer |
APR 2004 |
18 pages |
| Authors:
Peter Geck; TUFTS UNIV BOSTON MA
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| Prostate cancer is the second leading cause of death among American men. The present proposal extends the molecular progress in prostate cancer into clinical practice by developing innovative markers. The current androgen ablation treatment is initially therapeutic, but most patients relapse. A novel androgen substitution approach uses androgens to promote terminal differentiation and arrest cancer. Markers of differentiation, however, are not known in the prostate. We discovered a novel gene, ... |
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NOISE REDUCTION
