| Rapid Parallel Screening for Strain Optimization |
16 Nov 2012 |
5 pages |
| Authors:
Chuck Merryman; Tony Yee; J CRAIG VENTER INST ROCKVILLE MD
|
 | Progress has been made on identifying biosensors that will be used to report on the fermentation yields of industrially relevant biological compounds. Screening of the desired chemicals has been largely completed. Microbes that can utilize these compounds as their sole carbon source have been isolated and archived. Phylotyping of the isolated microbes is nearly finished and genomic DNA has been prepared for sequencing. In this reporting period, we have completed ... |
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| FOS: A Factored Operating Systems for High Assurance and Scalability on Multicores |
Aug 2012 |
27 pages |
| Authors:
Anant Agarwal; Jason Miller; David Wentzlaff; Harshad Kasture; Nathan Beckmann; Charles Gruenwald III; Christopher Johnson; MASSACHUSETTS INST OF TECH CAMBRIDGE
|
| fos is a new operating system design for multicores and cloud computing. It builds on previous work in distributed and microkernel OSes by factoring services out of the kernel, and then further distributing each service into a parallel, distributed fleet of cooperating processes. This design naturally spans non-coherent shared memory architectures and clusters of machines. Additionally it provides increased isolation between and within services, giving opportunities for increased reliability. This ... |
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| Efficient Cryosolid Positron Moderators |
Aug 2012 |
105 pages |
| Authors:
Mario E Fajardo; C M Lindsay; Christopher D Molek; AIR FORCE RESEARCH LAB EGLIN AFB FL MUNITIONS DIRECTORATE
|
| This report documents an in-house experimental effort to improve upon the ε 1% efficiency of state-of-the-art cryogenic solid neon positron moderators. We detail our rationale for why we expected an order-of-magnitude higher positron moderation efficiency from Rapid Vapor Deposited cryogenic parahydrogen solids. We describe our integration of a Matrix Isolation Spectroscopy capability into our Positron Moderation apparatus, which enables spectroscopic characterization of the cryogenic moderators. Despite all our hopes ... |
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| Androgenic Regulation of White Adipose Tissue-Prostate Cancer Interactions |
May 2012 |
23 pages |
| Authors:
Timothy C Thompson; M D ANDERSON CANCER CENTER HOUSTON TX
|
| Adipocyte stromal cells from WAT of both Glipr1 wild type adult males and Glipr1 knock out adult males were isolated and used for coculturing experiment. Coculturing prostate cancer cells (VCaP, RM-9, PC-3) with ASCs from WAT of Glipr1 KO and Glipr1 WT resulted in increased growth of the cancer cells compared to the cells grown without the ASCs. Moreover, the prostate cancer cells grown with Glipr1 KO ASCs resulted in ... |
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| Social Awareness and Action Training (SAAT) |
Apr 2012 |
36 pages |
| Authors:
John T Cacioppo; CHICAGO UNIV IL
|
| The aim of the research is to develop and evaluate the effects of a new training program--the Social Awareness & Action Training (SAAT)--on soldier resilience and performance prior to, during, and following deployment. In Phase 1 (Months 1-6), we adapted and evaluated the SAAT. Focus groups for the SAAT program were conducted at Fort Bliss in June 2011, resulting in revisions to the training. To determine the intervention effectiveness and ... |
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| Defeating Terrorism through a Politico-Military Strategy: The Sri Lankan Experience |
21 Mar 2012 |
84 pages |
| Authors:
Udaya Perera; ARMY WAR COLL CARLISLE BARRACKS PA
|
| Sri Lanka is an island nation situated near the southern tip of India. Its land mass is 25,332 square miles in extent, and it is blessed with a population of 21 million people who belong to three distinct ethic groups: Sinhalese (74%), Tamils (18%), and Muslims (7%). The colonial policy of Divide et impara and short-sighted policies of certain Sinhalese and Tamil extremist socialist and nationalist elements in the post-independence ... |
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| Maslow, Needs, and War |
28 Feb 2012 |
34 pages |
| Authors:
John P Baker; ARMY WAR COLL CARLISLE BARRACKS PA
|
| In our current thinking on war, we rely on political leaders to define the character of war and to provide military-achievable goals. In many cases, not understanding the background to these goals can lead to tragedy. Understanding where these goals come from, particularly the needs of the society they serve, will help military professionals achieve these goals. Maslow's hierarchy of needs is a well-known framework that can help in the ... |
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| An Enterobacter Plasmid as a New Genetic Background for the Transposon Tn1331 |
25 Nov 2011 |
6 pages |
| Authors:
Mohammad R Alavi; Vlado Antonic; Adrien Ravizee; Peter J Weina; Mina Izadjoo; Alexander Stojadinovic; WALTER REED ARMY MEDICAL CENTER WASHINGTON DC
|
| Genus Enterobacter includes important opportunistic nosocomial pathogens that could infect complex wounds. The presence of antibiotic resistance genes in these microorganisms represents a challenging clinical problem in the treatment of these wounds. In the authors screening of antibiotic-resistant bacteria from complex wounds, an Enterobacter species was isolated that harbors antibiotic-resistant plasmids conferring resistance to Escherichia coli. The aim of this study was to identify the resistance genes carried by one ... |
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| Multi-Family Group Intervention for OEF/OIF Traumatic Brain Injury Survivors and their Families |
Oct 2011 |
36 pages |
| Authors:
Deborah Perlick; BRONX VETERANS MEDICAL RESEARCH FOUNDATION INC (VETERANS AFFAIRS) NEW YORK
|
| The overall aim of this study was to evaluate the feasibility and preliminary efficacy of an intervention that adapts Dyck's civilian multi-family group treatment model (MFGT-TBI) for veterans with TBI and their families. The adapted treatment model is intended to improve the health, mental health, and quality of life of veterans and their families. A total of four MFGs will be established across three sites. Each MFG will include approximately ... |
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| Assessing Vulnerabilities in Interdependent Infrastructures Using Attacker-Defender Models |
Sep 2011 |
95 pages |
| Authors:
Cory A Dixon; NAVAL POSTGRADUATE SCHOOL MONTEREY CA
|
| Our economic and social welfare depend on certain critical infrastructures and key resources. Protecting these infrastructures is a challenge because they are complex, and as systems they are difficult to understand, predict and control. In addition, they do not operate in isolation, but are interdependent with other infrastructures. This presents a challenge for their modeling and analysis. Due to the complexity of modeling the operation of just a single infrastructure, ... |
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| CSSC Fish Barrier Simulated Rescuer Touch Point Results, Operating Guidance, and Recommendations for Rescuer Safety |
Sep 2011 |
60 pages |
| Authors:
Michael Slater; Norbert Yankielun; John Parker; Marion J Lewandowski; COAST GUARD NEW LONDON CT RESEARCH AND DEVELOPMENT CENTER
|
| The Chicago Sanitary and Ship Canal (CSSC) has electric dispersal barriers in operation to prevent the spread of aquatic nuisance species. The experiment was to better understand what would actually occur during a rescue in the electrified waters with three barriers energized. An additional purpose was to identify any methods, devices, or operating guidance to prevent potential harm to a rescuer. Voltage measurements under controlled conditions were taken during transits ... |
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| Population Enrichment and Isolation with Magnetic Sorting |
Sep 2011 |
22 pages |
| Authors:
Joshua M Kogot; Joseph M Pennington; Deborah A Sarkes; Dimitra N Stratis-Cullum; Paul M Pellegrino; ARMY RESEARCH LAB ADELPHI MD SENSORS AND ELECTRON DEVICES DIRECTORATE
|
| Manual and semi-automated sorting methods (MACS) provide a high-throughput, less costly method for sample enrichment compared to fluorescence activated cell sorting (FACS). Magnetic sorting methods use commercially available magnetic beads with many surface modifications available for customizable sorting methods. In this note, we outline the methods for magnetic cell sorting using manual and benchtop magnets (MACS), as well as a micromagnetic sorter (MMS) that uses diposable, microfluidic cartridges. Along with ... |
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| New Advanced Technologies In Stem Cell Therapy |
Sep 2011 |
52 pages |
| Authors:
Johnny Huard; PITTSBURGH UNIV PA
|
| We have isolated and characterized a population of skeletal muscle-derived stem cells (MDSCs) that display a greatly improved skeletal and cardiac muscle transplantation capacity when compared to skeletal muscle myoblasts. The MDSCs ability to withstand oxidative and inflammatory stresses appears to be the single most important factor for their improved transplantation capacity. Although the true origin of MDSCs remains unclear, their high degree of similarity with blood vessel-derived stem cells ... |
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| Using a Volume Bragg Grating Instead of a Faraday Isolator in Lasers Incorporating Stimulated Brillouin Scattering Wavefront Reversal or Beam Cleanup |
29 Aug 2011 |
6 pages |
| Authors:
John E McElhenny; Jeffrey O White; Steven D Rogers; Tigran Sanamyan; Leonid B Glebov; Oleksiy Mokhun; Vadim I Smirnov; ARMY RESEARCH LAB ADELPHI MD
|
| A master-oscillator power-amplifier with stimulated Brillouin scattering (SBS) beam cleanup or wavefront reversal typically incorporates a Faraday isolator to outcouple the Stokes light, limiting the power scalability. Volume Bragg gratings (VBGs) have the potential for scaling to higher powers. We report here the results of tests on a VBG designed to resolve wavelengths 0.060 nm apart, corresponding to the 16 GHz frequency shift for SBS backscattering at 1064 nm in ... |
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| Role of the ARF Tumor Suppressor in Prostate Cancer |
Aug 2011 |
29 pages |
| Authors:
Leonard B Maggi; WASHINGTON UNIV ST LOUIS MO
|
| The nucleolar tumor suppressor ARF plays an important role in the tumor surveillance of human cancer. We have found that ARF expression is absent from highly proliferative prostate adenocarcinomas. This correlates with the normal expression of the p53 tumor suppressor gene indicating that ARF loss could be a contributing factor for prostate cancer initiation and/or progression. We have found that ARF-mull mice develop prostatic lesions by 9 months of age ... |
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| Isolation and Characterization of Prostate Cancer Stem Cells |
Aug 2011 |
12 pages |
| Authors:
Isla Garraway; CALIFORNIA UNIV LOS ANGELES
|
| Human prostate epithelial cells that can develop into prostaspheres display characteristics of stem/progenitor cells, including self-renewal and ability to induce prostate tubule formation in vivo. FISH analysis of prostaspheres derived from patient specimens containing the TMPRSS-ERG translocation, however, are not preserved in sphere-forming cells. In order to evaluate whether prostate cancer stem cells containing the TMPRSS-ERG translocation can be isolated, we have proposed a series of experiments to isolate tumor ... |
|
| Deformable Bullnose Energy Absorbing System (BEAS). Report 2: Head-On Impact with a Deformable BEAS and Introducing a Collapsible Arch |
JUL 2011 |
125 pages |
| Authors:
Robert M. Ebeling; Barry C. White; Ralph W. Strom; Jr. Hite John E.; Bruce C. Barker; Richard W. Haskins; ENGINEER RESEARCH AND DEVELOPMENT CENTER VICKSBURG MS INFORMATION TECHNOLOGY LAB
|
| An impact between a tow and the bullnose of a lock approach wall can result in the tow breaking up with loose barges moving out of control toward the lock or navigation dam with serious consequences. Project operations can be severely affected or even shut down. The loose barges can cause a high safety risk to personnel involved and if the navigation pool is lost or the lock is damaged, ... |
|
| Understanding the North Korea Problem: Why It Has Become the "Land of Lousy Options" |
JUL 2011 |
83 pages |
| Authors:
William Boik; ARMY WAR COLL STRATEGIC STUDIES INST CARLISLE BARRACKS PA
|
| This monograph is intended to draw attention to the challenges faced by the United States in developing a coordinated strategy for dealing with North Korea. Despite the many decades of direct U.S. involvement on the Korean Peninsula, we continue to have little understanding of the North Korean culture or of events inside North Korea. We also do not have a long-term coordinated strategy for North Korea. Over the past decade, ... |
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| Protecting, Isolating, and Controlling Behavior: Population and Resource Control Measures in Counterinsurgency Campaigns |
10 JUN 2011 |
368 pages |
| Authors:
Mark E. Battjes; ARMY COMMAND AND GENERAL STAFF COLL FORT LEAVENWORTH KS
|
| Classical counterinsurgency theorists emphasize that it is necessary for the government to gain and maintain control of the population to defeat an insurgency. They describe population and resource control measures as a means of doing so. However, some contemporary writers have questioned the legitimacy of such tactics and doubt that they can be employed effectively in modern campaigns. Four case studies from three different campaigns, the Philippines, Vietnam, and Iraq, ... |
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| Information Sharing Between Platforms in DRDC's Networked Underwater Warfare Demonstration Trial |
JUN 2011 |
|
| Authors:
Marcel Lefrancois; DEFENCE RESEARCH AND DEVELOPMENT ATLANTIC DARTMOUTH (CANADA)
|
 | The final demonstration trial of Defence R&D Canada's (DRDC) Networked Underwater Warfare (NUW) Technology Demonstration Project (TDP) brought together 4 vessels and a reach-back centre to develop, maintain and share a single operating picture while performing anti-submarine warfare. Sensor information was shared by operators across platforms using network tools and chat applications in web pages and applications embedded within a DRDC developed Network Enabled Combat System (NECS). In all, 22 ... |
|
| Function of ZFAND3 in the DNA Damage Response |
Jun 2011 |
21 pages |
| Authors:
Bianca M Sirbu; VANDERBILT UNIV NASHVILLE TN
|
| The DNA-damage response (DDR) functions to maintain genomic integrity and prevent tumorigenesis. Cells in human precancerous lesions contain high levels of DNA damage, potentially resulting from unresolved problems accrued during DNA replication. Such replication stress can arise from stalling of replication forks at DNA lesions. The dynamic coordination of mechanisms that detect and repair these damaged replication forks is the subject of this research. Several mechanisms to repair a damaged ... |
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| The National Security Strategy: Development and Implementation in a New Era |
12 Apr 2011 |
32 pages |
| Authors:
Kurt J Pinkerton; TEXAS UNIV AT AUSTIN
|
| Since our nation's origin, the U.S. government has struggled with the development and implementation of a national security strategy. Throughout the decades, U.S. security policy appears to have been shaped by significant global events rather than by forethought on national security concerns. Throughout U.S. history, there have been three significant changes towards national security affairs. The National Security Act of 1947, the Goldwater/Nichols Act of 1986, and the establishment of ... |
|
| Ethnic Violence, Impact on Afghanistan |
08 Apr 2011 |
38 pages |
| Authors:
Robert Hanley; ARMY WAR COLL CARLISLE BARRACKS PA
|
| Violence has always been a part of the Afghan way of life. Despite beliefs that ethnic differences are the sole factors in triggering violence, there is no single cause of violence in Afghanistan's complex situation. This paper considers such issues as geography, regional and historical factors, ethnic make-up -- along with religious, political, economic, and social considerations. It concludes that ethnicity is not the only factor causing violence in Afghanistan, ... |
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| Battlefield Lessons: The Forward Air Surgical Team (FAST) Response |
24 Feb 2011 |
32 pages |
| Authors:
Mathew J Brady; AIR WAR COLL MAXWELL AFB AL
|
| Research with trauma models and battle zone experience have identified critical time frames in which the most seriously injured must reach and receive comprehensive trauma care. Patients getting care in these time frames have reduced morbidity and mortality. The one battlefield model that has not transitioned to domestic mass casualty and disaster response is the military triage model. First responders are forced to forfeit immediate life-saving services and interventions to ... |
|
| Identification of Genes Required for the Survival of BRCA 1-/- Cells |
Feb 2011 |
9 pages |
| Authors:
Stephen Elledge; BRIGHAM AND WOMENS HOSPITAL BOSTON MA
|
| A major obstacle for breast cancer drug discovery is target identification. Despite the wealth of information on copy number alterations and mutations recently available from sequencing efforts such as The Cancer Genome Atlas, identifying new targets for breast cancer therapeutics has proved challenging because causative perturbations cannot be determined from benign changes without functional studies. Genetic shRNA screens are powerful tools for identifying loss-of function phenotypes in mammalian cells and ... |
|
| Isolation and Characterization of Orientia tsutsugamushi from Rodents Captured following a Scrub Typhus Outbreak at a Military Training Base, Bothong District, Chonburi Province, Central Thailand |
Jan 2011 |
10 pages |
| Authors:
Wuttikon Rodkvamtook; Toon Ruang-areerate; Jariyanart Gaywee; Allen L Richards; Pimmada Jeamwattanalert; Dharadhida Bodhidatta; Noppadon Sangjun; Anchana Prasartvit; Araya Jatisatienr; Chaiwat Jatisatienr; NAVAL MEDICAL RESEARCH CENTER SILVER SPRING MD RICKETTSIAL DISEASES DEPT
|
| Orientia tsutsugamushi, an obligate intracellular Gram-negative bacterium, is the causative agent of scrub typhus, a vector-borne disease transmitted by infected chiggers (trombiculid mite larvae). In 2002, an outbreak of scrub typhus occurred among Royal Thai Army troops during the annual field training at a military base in Bothong district Chonburi province, central Thailand. This report describes the outbreak investigation including its transmission cycle. Results showed that 33.9% of 174 trained ... |
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| Centralized Execution, Decentralized Chaos: How the Air Force Is Poised to Lose a Cyber War |
2011 |
7 pages |
| Authors:
John Cobb; AIR AND SPACE POWER JOURNAL MAXWELL AFB AL
|
| In the current state of cyber warfare, massive centralized networks are at best fragile and often indefensible. The Air Force's network operations (AFNETOPS) paradigm relies on centralized control of the service's cyberspace; although arguably adequate for maintenance and counterintelligence in "cyber peacetime," it could fail spectacularly if ever tested by a serious cyber attack. At present, the Air Force relies on a handful of units from the 67th Network Warfare ... |
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| Synthetic Aperture Sonar (SAS) and Acoustic Templates for the Detection and Classification of Underwater Munitions |
Nov 2010 |
31 pages |
| Authors:
Steven G Kargl; Kevin L Williams; Aubrey L Espana; Raymond Lim; Jermaine L Kennedy; Rudy T Arrieta; Timothy M Marston; Joseph L Lopes; WASHINGTON UNIV SEATTLE APPLIED PHYSICS LAB
|
| This presentation will present a series of monostatic and bistatic acoustic scattering measurements were conducted to investigate discrimination and classification capabilities based on the acoustic response of targets for underwater unexploded ordnance (UXO) applications. The measurements were performed during March 2010 and are referred to as the Pond Experiment 2010 (PondEx10), where the fresh water pond contained a sand sediment. The measurements utilized a rail system with a mobile tower ... |
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| Oxytocin and Social Support as Synergistic Inhibitors of Aversive Fear Conditioning and Fear-Potentiated Startle in Male Rats |
Sep 2010 |
23 pages |
| Authors:
Jeffrey B Rosen; DELAWARE UNIV NEWARK
|
| The purpose of the grant is to test whether exogenous oxytocin acts as an antianxiety agent and whether social support facilitates its antianxiety effects in a fear-potentiated startle paradigm. Oxytocin given systemically (0.1 micrograms/kg, sc) effectively reduced background anxiety, but not specific cue-potentiated fear. This was found when oxytocin was given either before fear conditioning (acquisition), immediately after fear conditioning (consolidation), or before retrieval/expression of conditioned fear-potentiated startle. Social isolation ... |
|
| Biodegradation of Medium Chain Hydrocarbons by Acinetobacter venetianus 2AW Immobilized to Hair-Based Adsorbent Mats (Postprint) |
Sep 2010 |
10 pages |
| Authors:
Heather R Luckarift; Susan R Sizemore; Karen E Farrington; Preston A Fulmer; Justin C Biffinger; Lloyd J Nadeau; Glenn R Johnson; UNIVERSAL TECHNOLOGY CORP DAYTON OH
|
| The natural attenuation of hydrocarbons can be hindered by their rapid dispersion in the environment and limited contact with bacteria capable of oxidizing hydrocarbons. A functionalized composite material is described herein, that combines in situ immobilized alkanedegrading bacteria with an adsorbent material that collects hydrocarbon substrates, and facilitates biodegradation by the immobilized bacterial population. Acinetobacter venetianus 2AW was isolated for its ability to utilize hydrophobic n-alkanes (C10?C18) as the sole ... |
|
| Atomtronics: Research in Ultracold Atom Semiconductor Device Analogs |
01 Aug 2010 |
6 pages |
| Authors:
Dana Z Anderson; COLORADO UNIV AT BOULDER OFFICE OF CONTRACTS AND GRANTS
|
| Theoretical work established a quantum framework in which to address atom analogs of electronic devices and circuits. Initial focus was on isolated elements, particularly atom diodes and atom transistors. Two theoretical approaches addressed different device strategies, one based on double and triple potential wells, the other based on periodic structures that are analogous to semiconductor materials. The first approach is suited to implementations using ultracold atom chip technology, whereas the ... |
|
| Flame Propagation Enhancement by Plasma Excitation of Oxygen. Part 1. Effects of O3 |
Jan 2010 |
11 pages |
| Authors:
Timothy Ombrello; Sang H Won; Yiguang Ju; Skip Williams; PRINCETON UNIV NJ DEPT OF MECHANICAL AND AEROSPACE ENGINEERING
|
| The thermal and kinetic effects of O3 on flame propagation were investigated experimentally and numerically by using C3H8/O2/N2 laminar lifted flames. Ozone produced by a dielectric barrier plasma discharge was isolated and measured quantitatively by using absorption spectroscopy. Significant kinetic enhancement by O3 was observed by comparing flame stabilization locations with and without O3 production. Experiments at atmospheric pressures showed an 8% enhancement in the flame propagation speed for 1260 ... |
|
| Complementary Waveforms for Sidelobe Suppression and Radar Polarimetry |
Jan 2010 |
19 pages |
| Authors:
Yuejie Chi; Ali Pezeshki; A R Calderbank; COLORADO STATE UNIV FORT COLLINS DEPT OF ELECTRICAL AND COMPUTER ENGINEERING
|
| Advances in active sensing are enabled by the ability to control new degrees of freedom and each new generation of radar platforms requires fundamental advances in radar signal processing [1],[2]. The advent of phased array radars and space-time adaptive processing have given radar designers the ability to make radars adaptable on receive [2]. Modern radars are increasingly being equipped with arbitrary waveform generators which enable transmission of different waveforms across ... |
|
| Advanced Microwave Ferrite Research (AMFeR): Phase Four |
15-Oct-2009 |
27 pages |
| Authors:
Jeffrey L Young; IDAHO UNIV MOSCOW
|
| The purpose of this research endeavor is to devise ferrite materials for microwave, self-biased circulator applications. To this end, the research team focused on two key activities. The first was the development of a ferrite/epoxy composite that can be directly injected into a dielectric substrate. As the ferrite cured, two external magnets were placed on both sides of the ferrite to align the ferrite moments; once cured, the moments were ... |
|
| Integrating Intelligence and Building Teams Within the Infantry Immersion Trainer |
Sep-2009 |
229 pages |
| Authors:
Craig R Schwetje; NAVAL POSTGRADUATE SCHOOL MONTEREY CA MODELING VIRTUAL ENVIRONMENTS AND SIMULATION (MOVES)
|
| The trend of focusing on technology in technology augmented environments and practicing a set of skills in isolation needs to shift towards user-centered training with skills being integrated earlier in the training process, as long as conditions for that integration exist. The purpose of this thesis was to examine whether incorporating intelligence briefs and debriefs with a Squad Planning Operations Center (SPOC) supported by suitable technologies improved infantry training in ... |
|
| Iran's Economic Conditions: U.S. Policy Issues |
15-Jun-2009 |
|
| Authors:
Shayerah Ilias; LIBRARY OF CONGRESS WASHINGTON DC CONGRESSIONAL RESEARCH SERVICE
|
| The Islamic Republic of Iran, a resource-rich and labor-rich country in the Middle East, is a central focus of U.S. national security policy. The United States asserts that Iran is a state sponsor of terrorism and that Iran's uranium enrichment activities are for the development of nuclear weapons. To the extent that U.S. sanctions and other efforts to change Iranian state policy target aspects of Iran's economy as a means ... |
|
| Understanding an Insurgency: Achieving the United States' Strategic Objectives in Afghanistan |
29-May-2009 |
57 pages |
| Authors:
Jason T Williams; ARMY COMMAND AND GENERAL STAFF COLL FORT LEAVENWORTH KS SCHOOL OF ADVANCED MILITARY STUDIES
|
| The problems in Afghanistan are not simple and there is no single solution. Indeed, the problems in Afghanistan are not limited to Afghanistan. Instead, the problems extend to all of Afghanistan' immediate neighbors as well as, among others, the United States, NATO, Russia, Iran, and India. However, perhaps nowhere is the problem more pronounced than in Pakistan. Pakistan' relationships with Afghanistan and the rest of the world are heavily influenced ... |
|
| Isolation and Growth of Prostate Stem Cells and Establishing Cancer Cell Lines from Human Prostate Tumors |
May-2009 |
35 pages |
| Authors:
Donald Vander Griend; JOHNS HOPKINS UNIV BALTIMORE MD
|
| The objective of this proposal was to isolate, grow, and characterize normal prostate stem cells and establish new prostate cancer cell lines from fresh human prostate tissues. The hypothesis is that prostate stem cells express defined stem cell markers, self-renew, and require the use of a feeder layer which is necessary for the establishment of prostate cancer cell lines from primary tumors. The goal of Specific Aim I was to ... |
|
| The Sleep of the Saved and Thankful |
16-Mar-2009 |
38 pages |
| Authors:
Michael E Kiene; ARMY WAR COLL CARLISLE BARRACKS PA
|
| As Congress prepared a declaration of war against Japan after Pearl Harbor, one of the biggest questions they faced was whether they should also declare war on Germany. Many argued that the United States should declare war only on Japan, since Germany was not involved in the attack. The matter was soon resolved when Hitler acted first and declared war on the United States. But why did he declare war ... |
|
| How Much Can We Learn About Many-Body Concepts From a Single Atom or Molecule? |
09-Mar-2009 |
10 pages |
| Authors:
Chunlei Guo; ROCHESTER UNIV NY INST OF OPTICS
|
| This research project studies complex multielectron effects in isolated atoms and molecules. The study helps explore the overlap between atomic and condensed matter physics, particularly the usage of atomic physics to learn about many-body phenomena. Multielectron effects constitute many-body problems in atomic systems. However, the multielectron problems have not been traditionally appreciated in AMO physics since most problems in atoms and molecules can be understood through the single-independent- electron picture. ... |
|
| Preventing Iranian Nuclear Proliferation: A New U.S. Policy Towards Iran |
20-Feb-2009 |
14 pages |
| Authors:
G M Shorr; MARINE CORPS COMMAND AND STAFF COLL QUANTICO VA
|
| A cache of Iranian-made explosives is found in Iraq. Iranian speed boats harass U.S. Naval ships in the Straight of Hormuz and threaten violence. Iranian President Mahmoud Ahmadinejad threatens to wipe Israel off the map. The terrorist organizations Hezbollah and Hamas receive Iranian support. In recent years, Iran has been a thorn in the side of the United States' foreign interests. Iranian military actions and political posturing have been bold, ... |
|
| Four-Channel Threshold Detector With Optical Isolation |
Feb-2009 |
26 pages |
| Authors:
Mark R Morgenstern; ARMY RESEARCH LAB ADELPHI MD SENSORS AND ELECTRON DEVICES DIRECTORATE
|
| The four-channel window comparator discussed in this report is a safety switch that can be used to limit a range of test variables such as voltages, currents, temperatures or other values that can be scaled to a voltage within +-13 V. This device is simple, reliable, rugged, and requires no external control hardware or software. This module is scalable and reconfigurable to support nearly any test apparatus. |
|
| Seismic Characterization Study of the Advanced Inertial Test Laboratory (AITL) Report |
08-Dec-2008 |
95 pages |
| Authors:
Cleon Baker; William Rock; TEST SQUADRON ( 746TH) HOLLOMAN AFB NM
|
| The Advanced Inertial Test Laboratory (AITL) is the most seismically quiet test facility in the nation. However, due to poor isolation of newly installed environmental support equipment (ESE) and improper upkeeping of existing isolation, the seismic test environment has been compromised. In order to quantify the current seismic environment, this study was conducted from 24 July 07 to 26 March 08. This report presents the results of the study, along ... |
|
| The Effects of National Policy on Refugee Welfare and Related Security Issues: A Comparative Case Study of Lebanon, Egypt and Syria |
Dec-2008 |
99 pages |
| Authors:
Jessica E Cleary; NAVAL POSTGRADUATE SCHOOL MONTEREY CA
|
| The growing and persistent nature of todays protracted refugee situations pose significant threats to the host countries and regions that support these vulnerable people. While stateless, refugees fall under the protection of the international community and its laws. However, it is the effects of state policy that actually shape the living conditions and the opportunities available for refugees, and in turn influence the security repercussions they can set in motion. ... |
|
| Direct Fabrication of a-Si:H Thin Film Transistor Arrays on Plastic and Metal Foils for Flexible Displays |
Dec-2008 |
6 pages |
| Authors:
S M O'Rourke; D C Morton; G B Raupp; N Colaneri; J Haq; S M Venugopal; D R Allee; J P Kaminski; R Naujokaitis; J Dailey; D Bottesch; M Marrs; B P O'Brien; S K Ageno; E J Bawolek; C Moyer; D E Loy; E W Forsythe; ARIZONA STATE UNIV TEMPE
|
| In this paper we describe solutions to address critical challenges in direct fabrication of amorphous silicon thin film transistor (TFTs) arrays for high information content active matrix flexible displays for Army applications. For all flexible substrates a manufacturable handling protocol in automated display-scale equipment is required. For metal foil substrates the principal challenges are planarization and electrical isolation, and management of coefficient of thermal expansion induced stress (CTE mismatch) during ... |
|
| Close a Sure Road to Defeat in Afghanistan by Keeping the Lines of Communication Open |
31-Oct-2008 |
29 pages |
| Authors:
Scott E Erdelatz; NAVAL WAR COLL NEWPORT RI JOINT MILITARY OPERATIONS DEPT
|
| The President of the United States recently called for a comprehensive review of U.S. strategy in Afghanistan in the wake of increasing violence and a resurgent Taliban. Comments by the current Democratic and Republican Presidential candidates, and other senior leaders, indicate that additional U.S. forces will be sent to Afghanistan in the near future. It is, therefore, more important than ever to ensure that the United States has a reliable ... |
|
| Analysis of Satellite Communication as a Method to Meet Information Exchange Requirements for the Enhanced Company Concept |
01-Sep-2008 |
87 pages |
| Authors:
Matthew A Senn; James D Turner; NAVAL POSTGRADUATE SCHOOL MONTEREY CA
|
| In the Global War on Terrorism and future irregular battlefields, the Marine Corps will not only fight in large-scale conventional war against sizable military forces but it will also engage adversaries that utilize smaller sized units dispersed asymmetrically over vast geographical locations. To address this emerging threat, the Marine Corps is developing the Enhanced Company (EC) concept, with the aim of providing the company commander with the tools necessary to ... |
|
| Electroluminescence Efficiency Enhancement using Metal Nanoparticles |
22-Jun-2008 |
4 pages |
| Authors:
Richard A Soref; J B Khurgin; G Sun; AIR FORCE RESEARCH LAB HANSCOM AFB MA SENSORS DIRECTORATE
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| We apply the "effective mode volume" theory to evaluate enhancement of the electroluminescence efficiency of semiconductor emitters placed in the vicinity of isolated metal nanoparticles and their arrays. Using the example of an InGaN/GaN quantum-well active region positioned in close proximity to Ag nanospheres, we show that while the enhancement due to isolated metal nanoparticles is large, only modest enhancement can be obtained with ordered array of those particles. We ... |
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| The Brain Tourniquet: Physiological Isolation of Brain Regions Damaged by Traumatic Head Injury |
19-Jun-2008 |
22 pages |
| Authors:
Douglas S F Ling; Lie Yang; Sonia Afroz; ChangChi Hsieh; STATE UNIV OF NEW YORK DOWNSTATE MEDICAL CENTER BROOKLYN
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| The objective of this study was to assess the feasibility of the "brain tourniquet" concept, a new therapeutic approach to battlefield traumatic brain injury (TBI). The purpose of the brain tourniquet is to physiologically isolate damaged brain regions in order to allow head-injured warfighters to remain combat effective after sustaining brain trauma. This will also enhance recovery from this type of injury by preventing the spread of damage into otherwise ... |
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| Optical Phase Unwrapping in the Presence of Branch Points |
12-May-2008 |
15 pages |
| Authors:
Todd M Venema; Jason D Schmidt; AIR FORCE INST OF TECH WRIGHT-PATTERSON AFB OH
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| Strong turbulence causes phase discontinuities known as branch points in an optical field. These discontinuities complicate the phase unwrapping necessary to apply phase corrections onto a deformable mirror in an adaptive optics (AO) system. This paper proposes a non-optimal but effective and implementable phase unwrapping method for optical fields containing branch points. This method first applies a least-squares (LS) unwrapper to the field which isolates and unwraps the LS component ... |
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Reports by Keyword(s)
ISOLATION
