| Evaporation Rates of Chemical Warfare Agents Using 5-CM Wind Tunnels I. CASARM Sulfur Mustard (HD) from Glass |
Oct-2008 |
187 pages |
| Authors:
John Pence; Aaron Flowers; Chris V Giannaras; Erin Maloney; Joseph P Myers; Robert G Nickol; Kenneth B Sumpter; Carol A Brevett; H D Durst; Bruce E King; EDGEWOOD CHEMICAL BIOLOGICAL CENTER ABERDEEN PROVING GROUND MD
|
 | The evaporation of sulfur mustard (HD) from glass was studied as a function of temperature, drop size, and airflow rate. The evaporation rate was measured by collecting the HD vapor using thermal desorption tubes that were connected to the wind tunnel. The evaporation rate increased with higher temperature, drop size, and wind speed. Five different wind tunnels were used, and it was possible to fit all of the data generated ... |
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| Methods of Advanced Wound Management for Care of Combined Traumatic and Chemical Warfare Injuries |
21-Jul-2008 |
22 pages |
| Authors:
John S Graham; Thomas P Logan; Travis W Gerlach; James P Bonar; Richard J Fugo; Robyn B Lee; Matthew A Coatsworth; ARMY MEDICAL RESEARCH INST OF CHEMICAL DEFENSE ABERDEEN PROVING GROUND MD
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| Chemical warfare agents are potential threats to military personnel and civilians. The potential for associated traumatic injuries is significant. Damage control surgery could expose medical personnel to agents contaminating the wounds. The objectives of this study were to demonstrate efficacy of surgical decontamination and assess exposure risk to attending personnel. Methods: Weanling pigs were randomly assigned to 2 of 4 debridement tools (scalpel, BovieR knife, Fugo BladeR , and VersajetTM ... |
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| Quantitative UV Absorbance Spectra of Chemical Agents and Simulants |
MAR 2008 |
41 pages |
| Authors:
J. M. Lochner; Aaron M. Hyre; STEVEN D. CHRISTESEN; Kristina R. Gonser; EDGEWOOD CHEMICAL BIOLOGICAL CENTER ABERDEEN PROVING GROUND MD RESEARCH AND TECHNOLOGY DIR
|
| The quantitative UV absorption spectra of selected chemical agents and simulants have been measured for wavelengths in the near UV from 200 to 400 nm. Although these data are of interest in their own right, they are also necessary for predicting the sensitivity of UV Raman based detection systems. Of particular interest are the absorption values at 248.25 nm and 262 nm as these correspond to excitation wavelengths used by ... |
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| The Role of NAD+ Depletion in the Mechanisms of Sulfur Mustard-Induced Metabolic Injury |
Jan-2008 |
14 pages |
| Authors:
Margaret E Martens; William J Smith; ARMY MEDICAL RESEARCH INST OF CHEMICAL DEFENSE ABERDEEN PROVING GROUND MD
|
| Results of our previous studies on the chemical warfare agent sulfur mustard (2,2'-dichlorodiethyl sulfide) suggested that mustard-induced inhibition of glycolysis is not solely a function of NAD+ depletion. To define the role of NAD+ in mustard-induced metabolic injury, we examined the effects of mustard +/- niacinamide on energy metabolism in cultured human keratinocytes. Sulfur mustard caused concentration-dependent decreases in viable cell number and ATP content at 24 hours, but not ... |
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| Ambient Volatility of Bis-(2-Chloroethyl) Sulfide |
OCT 2007 |
18 pages |
| Authors:
James H. Buchanan; Leonard C> Buettner; David E. Tevault; EDGEWOOD CHEMICAL BIOLOGICAL CENTER ABERDEEN PROVING GROUND MD
|
| The volatility of bis-(2-chloroethyl) sulfide (HI)) has been measured in the presence of water vapor using methodology recently developed at the U.S. Army Edgewood Chemical Biological Center. Contrary to predictions based on ideal behavior as described by Raoult's Law, the volatility of HI) is virtually independent of ambient humidity. This result suggests that the re-evaporation of HI) after deposition into the environment is a function of temperature, wind speed, and ... |
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| Validation of FMTV Modular VHP/mVHP System and Fumigation Decontamination Process in a C-141B Starlifter Aircraft |
AUG 2007 |
124 pages |
| Authors:
Mark D. Brickhouse; Teri A. Lalain; Jerry W. Pfarr; Brian K. Maclver; John P. Lloyd; James E. Flowers; Brent A. Mantooth; Zach B. Zander; DAVID C. STARK; Matthew J. Shue; EDGEWOOD CHEMICAL BIOLOGICAL CENTER ABERDEEN PROVING GROUND MD RESEARCH AND TECHNOLOGY DIR
|
| The C141 test was designed to further demonstrate that decontaminating substrates contaminated with chemical and biological warfare threat materials, while maintaining a near constant hydrogen peroxide/ammonia fumigant concentration (500 ppm/30 ppm) and varying exposure durations during separately timed runs, was reproducible. The test was also designed to demonstrate the ability to consistently achieve effective kills on materials contaminated with biological and chemical challenges set by the Joint Portable Interior Decontamination ... |
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| Vaporous Hydrogen Peroxide (VHP) Decontamination of a C-141B Starlifter Aircraft: Validation of VHP and Modified VHP (mVHP) Fumigation Decontamination Process via VHP-Sensor, Biological Indicator, and HD Simulant in a Large-Scale Environment |
MAR 2007 |
63 pages |
| Authors:
Mark D. Brickhouse; Abe Turetsky; Brian K. MacIver; Jerry W. Pfarr; Theresa A. Lalain /Iain /McVey; Wendlyn Alter; John P. Lloyd; Jr Fonti Mark A.; EDGEWOOD CHEMICAL BIOLOGICAL CENTER ABERDEEN PROVING GROUND MD RESEARCH AND TECHNOLOGY DIR
|
| The chemical and biological weapons decontamination of a C-141B aircraft carried out during Oct-Nov 2004 is part of a Congressionally funded joint venture between U.S. Army Edgewood Chemical Biological Center and Strategic Technology Enterprises (STE)/STERIS Corporation, Inc., (Mentor, OH) to develop and demonstrate the suitability of vaporous hydrogen peroxide/modified vaporous hydrogen peroxide (VHP/mVHP) technology. The purpose of this exercise was to ensure that the vapor could be evenly distributed within ... |
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| Noninvasive Methods for Determining Lesion Depth from Vesicant Exposure |
2007 |
|
| Authors:
Ernest H. Braue Jr.; John S. Graham; Bryce F. Doxzon; Kelly A. Hanssen; Horace L. Lumpkin; Robert S. Stevenson; Robin R. Deckert; Stephen J. Dalal; Larry W. Mitcheltree; ARMY MEDICAL RESEARCH INST OF CHEMICAL DEFENSE ABERDEEN PROVING GROUND MD
|
 | Before sulfur mustard (HD) injuries can be effectively treated, assessment of lesion depth must occur. Accurate depth assessment is important because it dictates how aggressive treatment needs to be to minimize or prevent cosmetic and functional deficits. Depth of injury typically is assessed by physical examination. Diagnosing very superficial and very deep lesions is relatively easy for the experienced burn surgeon. Lesions of intermediate depth, however, are often problematic in ... |
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| The Role of Energy Metabolism in Cutaneous Sulfur Mustard Injury |
01 NOV 2006 |
7 pages |
| Authors:
M. E. Martens; ARMY MEDICAL RESEARCH INST OF CHEMICAL DEFENSE ABERDEEN PROVING GROUND MD
|
| Over the past 17 years, our research efforts have focused on systematic studies of the effects of sulfur mustard (2,2'-dichlorodiethyl sulfide, HD) on energy metabolism in human epidermal keratinocytes (KEK). Our objectives are to define mechanisms of HD-induced metabolic injury, determine their role in the cutaneous pathology observed and provide mechanistic information that can be used in development of vesicant agent medical countermeasures. We have characterized effects of HD on ... |
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| Use of Epidermolysis Bullosa Biomarkers in Models of Vesicant Injury |
SEP 2006 |
52 pages |
| Authors:
Donald R. Gerecke; RUTGERS - THE STATE UNIV PISCATAWAY NJ
|
| This study consisted of an SM time course study for gene expression of protease and extracellular matrix related genes and an evaluation of potential medical countermeasures for SM-induced injury in the mouse ear vesicant model. The specific aim of the time course study was to determine whether MMP and MMP substrate (laminin-332) gene expression levels are altered over time (6, 12, 24, 72, 168 h) in mouse ear skin topically ... |
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| Solid Thermally Stable Peroxide-Equivalent Chemical Warfare Agent Decontamination Reagent |
22 OCT 2005 |
99 pages |
| Authors:
Brian J. Blackstone; Linda Carleton; Chad M. Cucksey; Michael von Fahnestock; Laura Hernon-Kenny; Charles Hines; Adam Judd; Hani Karam; Fred Moore; Bruce Monzyk; BATTELLE MEMORIAL INST COLUMBUS OH
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| This project focused on the initial evaluation of potassium ferrate (VI) as an effective decontaminant for CWAs. The technical objectives were: (1) Quantify the extent, if any, to which a ferrate (VI)-based decontamination of HD and VX generated toxic degradation products. (2) Measure the thermal stability of potassium ferrate (VI) at 71 degrees C, in accordance with AR 70-38, under isothermal and cyclic temperature conditions. (3) Determine the decontamination yields ... |
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| Development of Medical Countermeasures to Sulfur Mustard Vesication |
17 AUG 2005 |
6 pages |
| Authors:
William J. Smith; Michael C. Babin; Robyn C. Kiser; Robert P. Casillas; ARMY MEDICAL RESEARCH INST OF CHEMICAL DEFENSE ABERDEEN PROVING GROUND MD
|
| Sulfur mustard (HD) is an alkylating agent with cytotoxic, mutagenic and vesicating properties. It use on the battlefield results in debilitating injuries to skin, eyes and the respiratory system (1, 2). To elucidate the toxic sequelae that follow cutaneous exposure to HD, the United States Army Medical Research Institute of Chemical Defense (USAMRICD) has undertaken a broad-based research program encompassing both intramural and extramural research. This report summarizes our current ... |
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| Molybdate/Peroxide Oxidation of Mustard in Microemulsions |
10 AUG 2005 |
5 pages |
| Authors:
Lawrence R. Procell; George W. Wagner; Yu-Chu Yang; Clifford A. Bunton; CALIFORNIA UNIV SANTA BARBARA DEPT OF CHEMISTRY AND BIOCHEMISTRY
|
| Environmentally friendly and non-corrosive methods to decontaminate the blister agent mustard (HD), bis(2-chloroethyl) sulfide, are currently being developed. HD may be rendered non-vesicant by oxidation to the corresponding sulfoxide. Results will be presented for the use of the mildly-basic molybdate/peroxide oxidant system to achieve this transformation. Reactions are performed in microemulsions to enable the dissolution of oily, water-isoluble mustard. |
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| Use of Epidermolysis Bullosa Biomarkers in Models of Vesicant Injury |
JUN 2005 |
39 pages |
| Authors:
Donald R. Gerecke; Carol L. Sabourin; RUTGERS - THE STATE UNIV NEW BRUNSWICKNJ
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| The chemical warfare agent sulfur mustard (HD) produces a delayed inflammatory response followed by blister formation in skin of exposed individuals. There is a similarity between HD-induced skin injury and the skin disease Epidermolysis Bullosa (EB) in both the morphology of the damage and the structural components involved. Both HD-induced injury and EB are believed to involve matrix metalloproteinases (MMPs), which play key roles in the disruption of connective tissue ... |
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| New Approaches towards the Elucidation of Epidermal-Dermal Separation in Sulfur Mustard-Exposed Human Skin and Directions for Therapy |
01 MAY 2005 |
|
| Authors:
Marijke Mol; PRINS MAURITS LABORATORIUM TNO RIJSWIJK(NETHERLANDS)
|
| This study sought to broaden knowledge about therapies for sulfur mustard (HD agent) exposure by examining the compound's mechanism of action. Results of experiments with a human skin ex vivo model show that apoptosis and metalloprotease activity are key elements in HD-induced skin pathogenesis, and that intervention in these two processes is successful in resisting microvesication and impairment of epidermal cells. The observation that pancaspase and metalloprotease inhibitors can prevent ... |
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| Domestic Preparedness Program: Phase 2 Sarin (GB) and Distilled Sulfur Mustard (HD) Vapor Challenge Testing of Commercial Self-Contained Breathing Apparatus Facepieces |
MAR 2005 |
18 pages |
| Authors:
Raymond R. Lins; Lee E. Campbell; EDGEWOOD CHEMICAL BIOLOGICAL CENTER ABERDEEN PROVING GROUND MD
|
| Results of performance testing of three types of commercial self- contained breathing apparatus (SCBA) facepieces are described. A series of tests were performed to determine sarin (GB) and distilled sulfur mustard (HD) vapor breakthrough of SCBA facepieces using manikin head form and simulated breathing. |
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| Development and Testing of a Colorimetric 96 Well Plate Assay for the Determination of HD Hydrolysis Rate in Various Formulations |
JAN 2005 |
18 pages |
| Authors:
Steven P. Harvey; Joseph J. DeFrank; EDGEWOOD CHEMICAL BIOLOGICAL CENTER ABERDEEN PROVING GROUND MD RESEARCH AND TECHNOLOGY DIR
|
| Previous aqueous studies using HD pre-dissolved in isopropanol have shown that the effectiveness of HD enzymatic degradation is a function of the homogeneity of the HD-water system. In this study, a microtiter plate assay was developed for the purpose of screening a series of compounds with the potential to increase the solubility or dispersion of HE) in an aqueous matrix. The assay used meta-cresol purple dye as a pH indicator ... |
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| Development and Testing of a Colorimetric 96 Well Plate Assay for the Determination of HD Hydrolysis Rate in Various Formulations |
JAN 2005 |
18 pages |
| Authors:
Steven P. Harvey; Joseph J. DeFrank; EDGEWOOD CHEMICAL BIOLOGICAL CENTER ABERDEEN PROVING GROUND MD RESEARCH AND TECHNOLOGY DIR
|
| Previous aqueous studies using HD pre-dissolved in isopropanol have shown that the effectiveness of HD enzymatic degradation is a function of the homogeneity of the HD-water system. In this study, a microtiter plate assay was developed for the purpose of screening a series of compounds with the potential to increase the solubility or dispersion of HD in an aqueous matrix. The assay used meta-cresol purple dye as a pH indicator ... |
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| Feasibility of Formulating DECON GREEN with Airfraft Deicing Fluid: VX, GD, and HD Reactivity |
JAN 2005 |
13 pages |
| Authors:
George W. Wagner; Lawrence R. Procell; Joseph B. Kiple; Jeffrey S. Taylor; Yu-Chu Yang; GEO-CENTERS INC ABERDEEN PROVING GROUND MD
|
| DECON GREEN is a reactive, universal decontaminant for VX, HD, and G agents composed of bicarbonate (baking soda), hydrogen peroxide, and alcohol. The use of two currently fielded aircraft deicing fluids, containing ethylene glycol and/or propylene glycol and water, as substitutes for the alcohol constituent was assessed by examining the VX, GD, and HD) reactivity in formulations using these materials. |
|
| Decon Green (trademark) |
17 NOV 2004 |
4 pages |
| Authors:
George W. Wagner; Lawrence R. Procell; Vikki D. Henderson; David C. Sorrick; Zoe A. Hess; David G. Gehring; Mark D. Brickhouse; EDGEWOOD CHEMICAL BIOLOGICAL CENTER ABERDEEN PROVING GROUND MD
|
| Decon Green (trademark) is a hydrogen peroxide-based decontaminant designed to replace DS2; it affords the broad-spectrum decontamination of chemical and biological warfare agents. Composed entirely of ingredients commonly found in cosmetics, detergents, laundry boosters, and vitamins, Decon Green (trademark) is extremely environmentally friendly and leaves no toxic residues. Decon Green (trademark) retains the low-temperature decontamination ability of DS2, but it is noncorrosive to aluminum and steel. Decon Green (trademark) is ... |
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| Vapor Pressure of Solid HD |
15 NOV 2004 |
16 pages |
| Authors:
James H. Buchanan; Leonard C. Buettner; David E. Tevault; EDGEWOOD CHEMICAL BIOLOGICAL CENTER ABERDEEN PROVING GROUND MD RESEARCH AND TECHNOLOGY DIR
|
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| Evaporation of Chemical Warfare Agent HD on Glass Surface Under Various Environmental Conditions |
15 NOV 2004 |
51 pages |
| Authors:
Seok H. Hong; Kenneth B. Sumpter; Robert Nickol; Wendel Shuely; EDGEWOOD CHEMICAL BIOLOGICAL CENTER ABERDEEN PROVING GROUND MD
|
| Environmental fate of the chemical warfare agents (CWA) is receiving increasing attention, since the evaluation of the contact or vapor hazard is the critical input for models employed to support decisions to determine the individual as well as collective protection level of the combatants. Once released, CWA might evaporate and be carried by the wind, sorb into the surface material, or both. This can be a function of not only ... |
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| Further Developments in Vapor Sampling Methodology Development for Laboratory Measurement of the Environmental Fate of HD on Surfaces |
15 NOV 2004 |
20 pages |
| Authors:
Robert G. Nickol; Terrence G. D'Onofrio; Wendel J. Shuely; J. Pence; H. D. Durst; S. H. Hong; K. B. Sumpter; D. J. Weber; GEO-CENTERS INC ABERDEEN PROVING GROUND MD
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| A Medical Research and Evaluation Facility (MREF) and Studies Supporting the Medical Chemical Defense Program (Task Order 0020): Evaluation of Decontamination Solutions for Use on Remains |
OCT 2004 |
69 pages |
| Authors:
James E. Estep; Carl T. Olson; BATTELLE MEMORIAL INST COLUMBUS OH
|
| Priority 1 - Embalming Fluid Effects on Chemical Warfare Agent- The objective was to determine if embalming fluids alone would significantly destroy chemical warfare agents (HD and VX) such that is would serve as a decontaminant. This would simplify the decontamination procedure and provide a cost savings to the Army. The study evaluated embalming fluids Rex 36, Hexaphene MA 64, and Polar Cavity FirmindexR 53, as potential decontamination material by ... |
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| Domestic Preparedness Program Evaluation of the RAID-M (Bruker Saxonia Analytik GmbH Rapid Alarm and Identification Device - Monitor) Against Chemical Warfare Agents Summary Report |
OCT 2004 |
25 pages |
| Authors:
John M. Baranoski; Terri L. Longworth; EDGEWOOD CHEMICAL BIOLOGICAL CENTER ABERDEEN PROVING GROUND MD
|
| This report characterizes the chemical warfare (CW) agent detection characteristics of the commercially available RAID-M. This instrument is an ion mobility spectrometer designed for detection and monitoring of chemical warfare agents. The instrument was tested against HD, GB, and GA vapor under various conditions. This report provides the emergency responders concerned with CW agent detection and verification an overview of the capabilities of the RAID-M. |
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| Domestic Preparedness Program Evaluation of the NEXTTEQ Civil Defense Kit(Trademark) Against Chemical Warfare Agents Summary Report |
OCT 2004 |
31 pages |
| Authors:
Terri L. Longworth; Robin L. Matthews; John M. Baranoski; EDGEWOOD CHEMICAL BIOLOGICAL CENTER ABERDEEN PROVING GROUND MD
|
| This report characterizes the chemical warfare (CW) agent detection characteristics of the commercially available NEXTTEQ Civil Defense Kit(trademark). The kit uses colorimetric detection tubes to detect the presence or absence of chemical warfare agents. The system was tested against HD, GB, and GA vapor under various conditions. This report provides the emergency responders concerned with CW agent detection and verification an overview of the capabilities of the Civil Defense Kit(trademark). ... |
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| Test Results of ChemiCover Dress Level B Suit to Challenge by Chemical and Biological Warfare Agents and Simulants |
SEP 2004 |
36 pages |
| Authors:
Robert S. Lindsay; Suzanne A. Procell; Elaina H. Harrison; Alex G. Pappas; EDGEWOOD CHEMICAL BIOLOGICAL CENTER ABERDEEN PROVING GROUND MD RESEARCH AND TECHNOLOGY DIR
|
| Swatches from one ChemiCover Level B protective suit were challenged with-liquid droplets of sarin (OB) and mustard (HD) using modifications of the static diffusion procedure described in Test Operations Procedure (TOP) 8-2-501. The cumulative mass of each agent that permeated each swatch was determined over time, and the results for all swatches were used to determine a weighted-average cumulative mass for the suit. From these data, a physiologically derived breakthrough ... |
|
| DECON GREEN (Trademark) Development and Chemical Biological Agent Efficacy Testing |
SEP 2004 |
20 pages |
| Authors:
George W. Wagner; Philip W. Bartram; Lawrence R. Procell; David C. Sorrick; Vikki D. Henderson; Abraham L. Turetsky; Vipin K. Rastogi; Yu-Chu Yang; EDGEWOOD CHEMICAL BIOLOGICAL CENTER ABERDEEN PROVING GROUND MD RESEARCH AND TECHNOLOGY DIR
|
| The development of DECON GREEN (Trademark) from its inception to the present is described, and efficacy data for VX, GD, TGD, HD, THD, and anthrax are presented. Examples of consumer products containing the identical or similar ingredients of DEC ON GREEN (Trademark) are given. The efficacy data reveals the tremendous decontamination efficacy afforded by a solvent-based, material-penetrating decontaminant. However, materials susceptible to agent absorption and absorption of the decontaminant are ... |
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| Domestic Preparedness: Sarin (GB) and Mustard (HD) Challenge and Protection Factor (PF) Testing of Escape Hoods, Draeger DefendAir and Fume Free Quick Mask 2000 |
JUN 2004 |
22 pages |
| Authors:
Lee E. Campbell; Adam D. Seiple; EDGEWOOD CHEMICAL BIOLOGICAL CENTER ABERDEEN PROVING GROUND MD RESEARCH AND TECHNOLOGY DIR
|
| Two escape hood designs (Draeger DefendAir and the Fume Free Quick Mask 2000) were tested to assess their capability to protect in a chemical warfare (CW) agent environment. A GB and HD vapor test was performed on both types of hoods and there was no breakthrough during the 65-minute tests. The hoods were also tested to assess their ability to protect the wearer from an aerosolized threat. Human test subjects ... |
|
| Domestic Preparedness Program Evaluation of the Nextteq Civil Defense Kit (TRADEMARK) Against Chemical Warfare Agents Summary Report |
MAY 2004 |
31 pages |
| Authors:
Terri L. Longworth; Robin L. Matthews; John M. Baranoski; EDGEWOOD CHEMICAL BIOLOGICAL CENTER ABERDEEN PROVING GROUND MD
|
| This report characterizes the chemical warfare (CW) agent detection characteristics of the commercially available NEXTTEQ Civil Defense Kit TM. The kit uses colorimetric detection tubes to detect the presence or absence of chemical warfare agents. The system was tested against HD, GB, and GA vapor under various conditions. This report provides the emergency responders concerned with CW agent detection and verification an overview of the capabilities of the Civil Defense ... |
|
| Vaporized Hydrogen Peroxide (VHP) Decontamination of VX, GD, and HD |
19 NOV 2003 |
6 pages |
| Authors:
George W. Wagner; David C. Sorrick; Lawrence R. Procell; Zoe A. Hess; Mark D. Brickhouse; Iain F. McVey; Lewis I. Schwartz; EDGEWOOD CHEMICAL BIOLOGICAL CENTER ABERDEEN PROVING GROUND MD
|
| Vaporized Hydrogen Peroxide (VHP) has been utilized for more than a decade to sterilize clean rooms and pharmaceutical processing equipment and, quite recently, to decontaminate anthrax-ridden buildings. VHP is also suitable for the decontamination of VX and HD, which readily converts these agents to ethyl methylphosphonic acid and bis(2-chloroethyl) sulfoxide, respectively. However, GD is quite stable in the presence of VHP. The simple addition of low-levels of ammonia gas renders ... |
|
| Correlation of Chemical Warfare Surrogate Tests on Air-Permeable Chemical Protective Uniforms |
18 NOV 2003 |
8 pages |
| Authors:
Elizabeth Klemperer; ARMY NATICK RESEARCH DEVELOPMENT AND ENGINEERING COMMAND MA INDIVIDUAL PROTECTION DIRECTORATE
|
| Air-permeable chemical protective uniforms provide percutaneous protection against chemical liquids released as vapor and droplets by adsorbing the chemical in a layer of activated carbon. The air that flows through the uniform fabric evaporates sweat, providing cooling. The protective capacity of a material is tested by measuring the breakthrough time of chemical warfare agent (CWA) applied on a sample at a vapor concentration and wind speed representing average field conditions. ... |
|
| Domestic Preparedness Program: Evaluation of the TravelIR HCI (trademark) Hazmat Chemical Identifier |
NOV 2003 |
37 pages |
| Authors:
Kwok Y. Ong; Frederick C. Baldauf; Diane C. St. Amant; Laurie F. Carey; EAI CORP ABINGDON MD
|
| This report characterizes the chemical warfare (CW) and biological warfare (BW) agent detection characteristics of the TravelIR HCI(Trademark) commercially available instrument from SensIR Incorporated (Danbury, CT). The TravelIR instruments were tested against HD), GB, GA, VX, and bio-simulant contained in various mixtures. This report is intended to provide the users concerned with CW agent detection an overview of the substance identification capabilities of the TravelIR. |
|
| Test Results of Phase 3 Level A Suits to Challenge by Chemical and Biological Warfare Agents and Simulants: Summary Report |
AUG 2003 |
50 pages |
| Authors:
Robert S. Lindsay; Suzanne A. Procell; Frederick C. Baldauf; Alex G. Pappas; EDGEWOOD CHEMICAL BIOLOGICAL CENTER ABERDEEN PROVING GROUND MD
|
| Swatches from four commercially-available Level A protective suits were challenged with liquid droplets of sarin ((GB) and mustard (HD) using modifications of the static diffusion procedure described in TOP 8-2-501. The cumulative mass of each agent that permeated each swatch was determined over time, and the results for all swatches were used to determine a weighted-average cumulative mass for each suit. From these data, a physiologically-derived breakthrough time was calculated ... |
|
| Test Results of Phase 3 Level A Suits to Challenge by Chemical and Biological Warfare Agent and Simulants: Executive Summary |
AUG 2003 |
15 pages |
| Authors:
Robert S. Lindsay; Alex G. Pappas; EDGEWOOD CHEMICAL BIOLOGICAL CENTER ABERDEEN PROVING GROUND MD
|
| Swatches from four commercially available Level A protective suits were challenged with liquid droplets of sarin (GB) and mustard (HD) using modifications of the static diffusion procedure described in TOP 8-2-501. The cumulative mass of each agent that permeated each swatch was determined over time, and the results for all swatches were used to determine a weighted-average cumulative mass for each suit. From these data, a physiologically-derived breakthrough time was ... |
|
| Domestic Preparedness Program Evaluation of the Raid-M (Bruker Saxonia Analytik GmbH Rapid Alarm and Identification Device - Monitor) Against Chemical Warfare Agents Summary Report |
AUG 2003 |
23 pages |
| Authors:
John M. Baranoski; Terri L. Longworth; EDGEWOOD CHEMICAL BIOLOGICAL CENTER ABERDEEN PROVING GROUND MD
|
| This report characterizes the chemical warfare (CW) agent detection characteristics of the commercially available RAID-M. This instrument is an ion mobility spectrometer designed for detection and monitoring of chemical warfare agents. The instrument was tested against HD, GB, and GA vapor under various conditions. This report provides the emergency responders concerned with CW agent detection and verification an overview of the capabilities of the RAID-M. |
|
| (27)Al, (47,49)Ti, (31)P, and (13)C MAS NMR Study oF VX, GB, GD and HD Reactions With Nanosize Al2O3, Al2O3, TiO2, Aluminum And Titanium |
01-Jul-2003 |
|
| Authors:
Shekar Munavalli; George W Wagner; Lawrence R Procell; EDGEWOOD CHEMICAL BIOLOGICAL CENTER ABERDEEN PROVING GROUND MD
|
| Assorted reactions of VX, GB, GD and HD with Al2O3, TiO2 (anatase and rutile), aluminum and titanium metal powders have been studied by 27Al, 47,49Ti, 31P and 13C MAS NMR. VX, GB, GD and HD hydrolyze on both nanosize and conventional Al2O3. A significant droplet size effect on the reaction kinetics is observed. For VX, GB and GD, 27Al and 31P MAS NMR detect the formation of stable, precipitated aluminum ... |
|
| Chemical Agent Hydrolysis on dry and Humidified Adsorbents |
JUL 2003 |
33 pages |
| Authors:
David McGarvey; John Mahle; George Wagner; EDGEWOOD CHEMICAL BIOLOGICAL CENTER ABERDEEN PROVING GROUND MD
|
| This study considers the rate of reaction of GB, GD, VX, and HD on selected adsorbents measured using a solid phase NMR technique. The adsorbents in dry and humidified conditions are exposed to the chemical agents. The rate of disappearance of the starting chemical over time is used to calculate a reaction half time and first order reaction rate. The appearance of reaction product peaks are also noted. The half ... |
|
| Domestic Preparedness Program Evaluation of the IMS20000 (trademark) (Bruker Daltonics GmbH Ion Mobility Spectrometer 2000) Against Chemical Warfare Agents Summary Report |
JUL 2003 |
29 pages |
| Authors:
John M. Baranoski; Terri L. Longworth; EDGEWOOD CHEMICAL BIOLOGICAL CENTER ABERDEEN PROVING GROUND MD RESEARCH AND TECHNOLOGY DIR
|
| This report characterizes the chemical warfare (CW) agent detection characteristics of the commercially available IMS2000TM. This instrument is an ion mobility spectrometer, designed for detection and monitoring of chemical warfare agents and industrial toxins. The instrument was tested against HD, GB, and GA vapor under various conditions. . This report provides the emergency responders concerned with CW agent detection and verification an overview of the capabilities of the IMS2000TM. |
|
| Domestic Preparedness Program: Sarin (GB) and Distilled Sulfur Mustard (HD) Vapor Challenge Testing of Commercial Self-Contained Breathing Apparatus |
JUL 2003 |
17 pages |
| Authors:
Raymond R. Lins; Lee E. Campbell; Aaron M. Hyre; EDGEWOOD CHEMICAL BIOLOGICAL CENTER ABERDEEN PROVING GROUND MD
|
| Results of performance testing of six NIOSH approved commercial self-contained breathing apparatus (SCBA) face piece designs are described. A series of tests was performed to determine Sarin (GB) and distilled sulfur mustard vapor breakthrough of SCBA face pieces using manikin head form and simulated breathing. |
|
| Water-Based Ensemble Coating |
03 JUN 2003 |
76 pages |
| Authors:
Bryan M. Smith; Jeff Lind; John Monroe; Suzanne Smerjac; Jianhan Yu; TDA RESEARCH INC WHEAT RIDGE CO
|
| In this project, TDA successfully developed and demonstrated a safe and effective prophylactic coating to achieve very effective decontamination of porous substrates with a water wash. The coating is particularly effective against G-agents (virtually complete protection), and is also very effective against sulfur mustard, agent MD, reducing heavy (10 g/sq m) MD contamination by over 99.5% when rinsed with water. The coating does require considerable water to rinse and therefore ... |
|
| Test Results of Phase 3 Level B Suits to Challenge by Chemical and Biological Warfare Agents and Simulants: Summary Report |
JUN 2003 |
42 pages |
| Authors:
Robert S. Lindsay; Suzanne A. Procell; Frederick C. Baldauf; Alex G. Pappas; EDGEWOOD CHEMICAL BIOLOGICAL CENTER ABERDEEN PROVING GROUND MD
|
| Swatches from three commercially available Level B protective suits were challenged with liquid droplets of Sarin (GB) and mustard (HD) using modifications of the static diffusion procedure described in TOP 8-2-501. The cumulative mass of each agent that permeated each swatch was determined over time, and the results for all swatches were used to determine a weighted-average cumulative mass for each suit. From these data, a physiologically-derived breakthrough time was ... |
|
| A Medical Research and Evaluation Facility (MREF) and Studies to Support the Medical Chemical Defense Program |
JUN 2003 |
57 pages |
| Authors:
Carl T. Olson; James E. Estep; BATTELLE MEMORIAL INST COLUMBUS OH
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| Battelle's Medical Research and Evaluation Facility (MREF) successfully maintained and functioned in compliance with local, state, and federal government regulations for developing and improving medical countermeasures against military relevant chemical agents. Fourteen task orders were proposed and/or developed. |
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| Test Results of Air-Permeable Charcoal Impregnated Suits to Challenge by Chemical and Biological Warfare Agents and Simulants. Executive Summary and Summary Report |
MAY 2003 |
82 pages |
| Authors:
Robert S. Lindsay; Alex G. Pappas; John M. Baranoski; EDGEWOOD CHEMICAL BIOLOGICAL CENTER ABERDEEN PROVING GROUND MD RESEARCH AND TECHNOLOGY DIR
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| Swatches from five commercially available air-permeable charcoal impregnated protective suits were challenged with liquid droplets of Sarin (GB) and mustard (HD), using modifications of the convective permeation test procedure described in TOP 8-2-501. The cumulative mass of each agent that permeated each swatch was determined over time. and the results for all swatches were used to determine a weighted-average cumulative mass for each suit. From these data a physiologically derived ... |
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| Testing of HAZMATCAD(TM) Detectors Against Chemical Warfare Agents: Summary Report of Evaluation Performed at U.S. Army Soldier Biological and Chemical Command (SBCCOM) |
MAY 2003 |
19 pages |
| Authors:
Juan C. Cajigas; Terri L. Longworth; Norman Davis; Kwok Y. Ong; EAI CORP ABINGDON MD
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| This report characterizes the chemical warfare agent (CWA) detection potential of the commercially available 250 mHz HAZMATCAD(TM). The HAZMATCAD(TM) instruments were tested against HD, GB, and GA vapors under various conditions. This report is intended to provide the users concerned with CWA detection an overview of HAZMATCAD's(TM) CWA detection capabilities. |
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| Test Results of Phase 3 Level B Suits to Challenge by Chemical and Biological Warfare Agents and Simulants: Executive Summary |
MAY 2003 |
15 pages |
| Authors:
Robert S. Lindsay; Alex G. Pappas; EDGEWOOD CHEMICAL BIOLOGICAL CENTER ABERDEEN PROVING GROUND MD RESEARCH AND TECHNOLOGY DIR
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| Swatches from three commercially available Level B protective suits were challenged with liquid droplets of Sarin (GB) and mustard (HD), using modifications of the static diffusion procedure described in TOP 8-2-301. The cumulative mass of each agent that permeated each swatch was determined over time, and the results for all swatches were used to determine a weighted-average cumulative mass for each suit. From these data, a physiologically derived breakthrough time ... |
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| Testing of HAZMATCAD Detectors Against Chemical Warfare Agents: Summary Report of Evaluation Performed at Soldier Biological and Chemical Command (SBCCOM) |
JAN 2003 |
20 pages |
| Authors:
Juan C. Cajigas; Terri L. Longworth; Norm Davis; Kwok Y. Ong; EDGEWOOD CHEMICAL BIOLOGICAL CENTER ABERDEEN PROVING GROUND MD
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| This report characterizes the chemical warfare (CW) agent detection potential of the commercially available 250 mHz HAZMATCAD TM. The HAZMATCAD instruments were tested against HD, GB, and GA vapors under various conditions. This report is intended to provide the users concerned with CW agent detection an overview of the CWA detection capabilities of the HAZMATCAD. |
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| Ambient Reactive Sorption OF CW Simulants on Cation Exchanged Zeolites |
25 NOV 2002 |
4 pages |
| Authors:
Howard Greene; Philip Morrison; Meghan Swanson; CASE WESTERN RESERVE UNIV CLEVELAND OH
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| Zeolite sorbent/catalyst materials were prepared, characterized and then utilized to determine their surface interactions at ambient temperature with common CW simulants for VX and HD. From this research, new insights regarding reactive sorption pathways of simulants on exchanged zeolites at ambient temperature have been proposed which will aid in developing superior alternates for sorption and detoxification of CW agents in the field. Experiments utilized a Bomem FTIR spectrometer with Harrick ... |
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| Domestic Preparedness Program: Testing of the VaporTracer Against Chemical Warfare Agents |
NOV 2002 |
27 pages |
| Authors:
Terri L. Longworth; Kwok Y. Ong; John M. Baranoski; EDGEWOOD CHEMICAL BIOLOGICAL CENTER ABERDEEN PROVING GROUND MD
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| This report characterizes the chemical warfare (CW) agent detection potential of the commercially available VaporTracer. The VaporTracer instruments were tested against HD, GB, and GA vapor under various conditions. This report is intended to provide the emergency responders concerned with CW agent detection an overview of the detection capabilities of the VaporTracer. |
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| Decontamination of GF In Vivo by the Reactive Skin Decontaminant Lotion (RSDL) |
SEP 2002 |
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| Authors:
R. W. Bide; D. J. Risk; DEFENCE RESEARCH AND DEVELOPMENT SUFFIELD (ALBERTA)
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| The Reactive Skin Decontaminant Lotion (RSDL)(R), developed for the CF, was tested for potency against GF using the same procedures previously used with GD, VX, L and HD. |
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Reports by Keyword(s)
HD AGENT
