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Reports by Keyword(s)COMPUTER PROGRAMMING
Total Results: 10587 Pages: Previous [1] 2 3 4 5 6 7 8 9 10 11 Next Results per page:
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Reducing Spreadsheet Errors Sep-2009 14 pages
Authors:  S K McKay; CORPS OF ENGINEERS WASHINGTON DC ECOSYSTEM MANAGEMENT AND RESTORATION RESEARCH PROGRAM
The full text of this report is available for sale.Increasing computational power and memory capacity in desktop computers has resulted in access to numerical techniques previously unavailable to many users. Although computational capabilities have increased, many users are unable to take full advantage of this power due to limited programming expertise. Spreadsheets offer these users a means to capitalize upon computational potential without extensive training, though spreadsheet models can confer risks due to high error rates and lack of ...


Developing a Modular Framework for Implementing a Semantic Search Engine Sep-2009 99 pages
Authors:  Brian M Hawkins; NAVAL POSTGRADUATE SCHOOL MONTEREY CA
The full text of this report is available for sale.Current methods of information retrieval (IR) are adequate for everyday search needs, but they are not appropriate for many military and industrial tasks. The underlying mechanism of typical search methods is based upon keyword matching, which has demonstrated very poor performance over highly technical requirements documents found within the field of acquisitions. Instead of matching keywords, IR methods that understand the meaning of the words in a query are needed ...


Designing a Sensorless Torque Estimator for Direct Torque Control of an Induction Motor Sep-2009 87 pages
Authors:  Athanasios Tsoutsas; NAVAL POSTGRADUATE SCHOOL MONTEREY CA DEPT OF ELECTRICAL AND COMPUTER ENGINEERING
The full text of this report is available for sale.Nowadays, transportation is a major cause of air pollution. Electric propulsion could replace the internal combustion engines of automobiles and reduce the emission of exhaust gases. The propulsion of an electric vehicle requires the design of an accurate electromagnetic torque estimator and an efficient control system in order to control the speed of the vehicle. This concept is conveyed through this thesis. An electromagnetic torque calculator of an induction motor ...


Finding Bent Functions Using Genetic Algorithms Sep-2009 199 pages
Authors:  Stuart W Schneider; NAVAL POSTGRADUATE SCHOOL MONTEREY CA DEPT OF ELECTRICAL AND COMPUTER ENGINEERING
The full text of this report is available for sale.In this thesis, a generic genetic algorithm (GA) is presented that is implemented on a reconfigurable computer. Our GA is implemented such that many problems can be solved by simply adapting the problem to the GA. For example, part of this process involves the customization of the fitness function of the given problem to the GA. The size of the problem is limited by the capacity of a field programmable ...


New Approaches for Prostate Cancer Combination Therapy Apr-2009 34 pages
Authors:  Luiz F Zerbini; BETH ISRAEL DEACONESS MEDICAL CENTER BOSTON MA
The full text of this report is available for sale.The mechanisms underlying the antineoplastic actions of NSAIDs remain poorly understood. We started deciphering now the mechanisms by which NSAIDs induce programmed cell death and growth arrest in cancer. In this report we show that induction of the pro-apoptotic cytokine melanoma differentiation associated gene-7/Interleukin-24 (MDA-7/IL-24) and the expression of growth arrest and DNA damage inducible (GADD) 45 alpha and gamma by several NSAIDs is an essential step for G2/M growth ...


Optimizing Multi-Ship, Multi-Mission Operational Planning for the Joint Force Maritime Component Commander Mar-2009 84 pages
Authors:  Robert A Silva; NAVAL POSTGRADUATE SCHOOL MONTEREY CA
The full text of this report is available for sale.Operational-level planners in Maritime Operations Centers aim to assign naval forces in support of combatant commanders efficiently and effectively, but they lack a software-based planning tool to develop optimal ship employment schedules. They must assign ships to particular missions spread throughout numerous regions over a particular time horizon to meet the combatant commander's force requirements. Currently, this is a manual process. We present Navy Mission Planner (NMP), a decision aid ...


Z Support in the HiVe Mathematical Toolkit Mar-2009 65 pages
Authors:  Jim McCarthy; Brendan Mahony; Linh Vu; Kylie Williams; DEFENCE SCIENCE AND TECHNOLOGY ORGANISATION EDINBURGH (AUSTRALIA) COMMAND CONTROL COMMUNICATIONS AND INTELLIGENCE DIV
The full text of this report is available for sale.The HiVe project is an ambitious research programme aimed at providing DSTO and the Australian Defence Department with the world's most advanced assurance tools. A key part of this is the provision of advanced high assurance analysis tools in the form of the HiVe Modeller component. Formal specification and system modelling activities in the HiVe Modeller are supported through an Isabelle/HOL implementation of the HiVe Mathematical Toolkit. This report describes ...


Reduced Precision Redundancy Applied to Arithmetic Operations in Field Programmable Gate Arrays for Satellite Control and Sensor Systems Dec-2008 175 pages
Authors:  Margaret A Sullivan; NAVAL POSTGRADUATE SCHOOL MONTEREY CA
The full text of this report is available for sale.This thesis examines two problems in on-board computing for space vehicles and develops rules for applying Reduced Precision Redundancy (RPR) as a new method of fault tolerance in Field Programmable Gate Arrays against Single Event Effects due to radiation on orbit. RPR was discovered by Snodgrass in 2006 and was first demonstrated using the single-input CORDIC algorithm. This research applies RPR to elementary multiple-input arithmetic operations (addition, subtraction, multiplication, division) ...


Efficient Implementation of Filtering and Resampling Operations on Field Programmable Gate Arrays (FPGAs) for Software Defined Radio (SDR) Dec-2008 79 pages
Authors:  Georgios Giannoulis; NAVAL POSTGRADUATE SCHOOL MONTEREY CA
The full text of this report is available for sale.In Software Defined Radios a good portion (or even the entirety) of the modulation and demodulation processes is performed in the digital domain. The data rate of the transmitted information is very important, since efficiency is a key requirement in real time implementations and cost increases considerably with the number of samples per second to be processed. In this thesis, we address the problem of efficient design of the resampling ...


Threshold Voltage Instability in A-Si:H TFTS and the Implications for Flexible Displays and Circuits Dec-2008 9 pages
Authors:  Z Li; E Forsythe; G Raupp; K Baugh; E Bawolek; N Darbanian; S Venugopal; R Shringarpure; L Clark; D Allee; D Morton; ARIZONA STATE UNIV TEMPE
The full text of this report is available for sale.After a brief review of the characteristics of electrical stress degradation of flexible, amorphous silicon thin film transistors, the implications for various types of flexible circuitry including active matrix backplanes, integrated drivers and general purpose digital circuitry are examined. A circuit modeling tool that enables the prediction of complex circuit degradation is presented. Experimental results for a variety of flexible digital circuits including programmable logic arrays and memories are presented. ...


Distributed Planning in a Mixed-Initiative Environment: Collaborative Technologies for Network Centric Operations Oct-2008 23 pages
Authors:  Joseph A Carozzoni; Chad C DeStefano; Kurt K Lachevet; AIR FORCE RESEARCH LAB ROME NY INFORMATION DIRECTORATE
The full text of this report is available for sale.The USAF Command and Control (C2) is undergoing a transformation to enable a full-spectrum, joint warfighting capability. To be able to meet the future challenge of employing forces anywhere in the world in support of national security objectives, the USAF requires a highly synchronized, distributed planning and re-planning capability that is flexible to adapt to any level of conflict. This paper describes an in-house program underway at the USAF Research ...


Programming Development Funds to Support a Counterinsurgency. Nangarhar, Afghanistan 2006 01-Sep-2008 19 pages
Authors:  Michelle Parker; NATIONAL DEFENSE UNIV WASHINGTON DC CENTER FOR TECHNOLOGY AND NATIONAL SECURITY POLICY
The full text of this report is available for sale.Introduction This paper describes one method of programming development funds at a sub-national level to positively affect a counterinsurgency, in this case, in Eastern Afghanistan. It is presented as a practical model for both students in the classroom and operators in the field to understand the complexity of a type of mission that the United States has not attempted since Vietnam. The paper explores how one interagency group, the Jalalabad ...


Design and Implementation of a Motor Incremental Shaft Encoder 01-Sep-2008 119 pages
Authors:  La; Andrew M Valley; NAVAL POSTGRADUATE SCHOOL MONTEREY CA
The full text of this report is available for sale.The Department of Electrical and Computer Engineering at the Naval Postgraduate School continuously develops new design applications and searches for new ways to arm the students with the tools necessary to gain a greater understanding of advanced motor applications. One such tool is the Student Design Center (SDC). The SDC utilizes Field Programmable Gate Array (FPGA) technology for digital control of motor applications. One of the key factors in motor ...


Modeling and Simulation of a Non-Coherent Frequency Shift Keying Transceiver Using a Field Programmable Gate Array (FPGA) 01-Sep-2008 125 pages
Authors:  Konstantinos Voskakis; NAVAL POSTGRADUATE SCHOOL MONTEREY CA
The full text of this report is available for sale.In this thesis, the principals of Software Defined Radio are demonstrated by implementing a Binary Frequency Shift Keying (BFSK) receiver-transmitter in a Field Programmable Gate Array (FPGA). After introducing the theory behind the Non- Coherent BFSK demodulation implemented at the receiver, the design of transmitter and receiver is illustrated. The design environment of choice is Mathworks Simulink and Xilinx System Generator, a dedicated library for Mathworks Simulink. The design is ...


IChart: A Graphical Tool to View and Manipulate Force Management Structure Databases Sep-2008 64 pages
Authors:  Frederick S Brundick; Hartwig; George W Jr; Samuel C Chamberlain; ARMY RESEARCH LAB ABERDEEN PROVING GROUND MD COMPUTATIONAL AND INFORMATION SCIENCES DIR
The full text of this report is available for sale.Maintaining a high-resolution force structure that may be shared among various organizations is a difficult task. One approach is to design databases which store Global Force Management (GFM) data in the form of time-based tree graphs, using enterprise identifiers (EIDs) as unique surrogate keys. This report is the manual, users' guide, and general documentation for the IChart application, which is intended to be a guide and demonstration of the utility ...


An Engineering Context for Software Engineering Sep-2008 139 pages
Authors:  Richard D Riehle; NAVAL POSTGRADUATE SCHOOL MONTEREY CA
The full text of this report is available for sale.New engineering disciplines are emerging in the late Twentieth and early Twenty-first Century. One such emerging discipline is software engineering. The engineering community at large has long harbored a sense of skepticism about the validity of the term software engineering. During most of the fifty-plus years of software practice, that skepticism was probably justified. Professional education of software developers often fell short of the standard expected for conventional engineers; software ...


Engineering the Space Age: A Rocket Scientist Remembers 01-Jul-2008 280 pages
Authors:  Robert V Brulle; AIR UNIV PRESS MAXWELL AFB AL
The full text of this report is available for sale.Rarely is a reader exposed to such an extraordinary, multifaceted presentation of aerospace technology as Bob Brulle narrates in this book. After returning from duty as a combat fighter pilot in World War II, this Belgian immigrant developed a multitalented and innovative aerospace career path that addressed many of the aerospace professions. Along the way he forged a career in the aviation and space field that resulted in his participating ...


Extreme C2 and Multi-Touch, Multi-User Collaborative User Interfaces 01-Jun-2008 31 pages
Authors:  Robert Regal; Don Pacetti; SPACE AND NAVAL WARFARE SYSTEMS CENTER NORTH CHARLESTON SC
The full text of this report is available for sale.The purpose of this paper is to introduce two things, the concept of Extreme C2 and a technological implementation for this collaborative, net-centric concept. Extreme C2 is a concept that applies elements of the eXtreme Programming (XP) concept. This collaborative development technique can increase the adaptability and quality of software, something of high value in the complex domain of enterprise software. When fused with net-centric concepts, Automated Battle Management Aids ...


Preventing SQL Code Injection by Combining Static and Runtime Analysis 01-May-2008 68 pages
Authors:  Wenke Lee; Adam Shostack; Alessandro Orso; GEORGIA INST OF TECH ATLANTA
The full text of this report is available for sale.Many software systems have evolved to include a Web-based component that makes them available to the public via the Internet and can expose them to a variety of Web-based attacks. One of these attacks is SQL injection, which can give attackers unrestricted access to the databases underlying Web applications and has become increasingly frequent and serious. In this project, we developed techniques and tools to detect, prevent, and report SQL ...


Identification of Pro-Differentiation p53 Target Genes and Evaluation of Expression in Normal and Malignant Mammary Gland 01-Apr-2008 36 pages
Authors:  Hua Li; DARTMOUTH COLL HANOVER NH
The full text of this report is available for sale.Delta-N-p63 plays a critical role in making decision to preserve or forfeit mammary stem cells/progenitor cells self-renewal capacity. In embryonic stem cells, some transcription factors including oct3/4, nanog, c-myc and Klf-4 are critical to maintain self-renewal and multi-potential stasis. Our study revealed that these key transcription factors also exist in adult mammary stem cells/progenitor cells as well as breast cell lines such as IMEC, MCF-10A, SUM102 and MCF- 7 cells. ...


Investigation of a Putative Estrogen-Imprinting Gene, Phosphodiesterase Type IV Variant (Pde4d4), in Determining Prostate Cancer Risk 01-Apr-2008 74 pages
Authors:  Wan-Yee Tang; CINCINNATI UNIV OH
The full text of this report is available for sale.Estrogens are known to play a role in the initiation and progression of prostate cancer. Recently, environmental factors such as xenoestrogens have been reported on their prevalence of prostate diseases or cancers. Estrogen imprinting of the prostate gland is believed to associate with an increased incidence of prostatic lesions including inflammation, epithelial hyperplasia, squamous metaplasia, dysplasia and adenocarcinoma. And DNA methylation may be one of the possible mechanisms of the ...


Functional Analysis of BORIS, a Novel DNA Binding Protein APR 2008 12 pages
Authors:  Paul Yaswen; CALIFORNIA UNIV BERKELEY
The full text of this report is available for sale.BORIS (cT6FL) is a paralog of tbe gene encoding CTCF, a multifunctional DNA binding protein that utilizes different sets of zinc fingers to mediate distinct gene regulatory functions, including those involved in cell growth regulation. Unlike CTCF the expression of BORIS is normally restricted to specific cells in testes (the only cells where CTCF is not expressed) where it may play a role in reprogramming the methylation pattern of male ...


Developing Fleets of Autonomous Underwater Vehicles 31-Mar-2008 11 pages
Authors:  Dean B Edwards; IDAHO UNIV MOSCOW CENTER FOR INTELLIGENT SYSTEMS RESEARCH
The full text of this report is available for sale.Autonomous underwater vehicles (AUVs) have a demonstrated capability to collect valuable data for scientific and military purposes. Historically, individual vehicles have been used. To reduce the overall time and cost of acquiring data over large areas, multiple vehicles must be used. A fleet of 5 AUVs, capable of underwater commendation, were fabricated. Languages and logics were developed to enable collaborative operations among the vehicles. Experiments with a formation of 5 ...


Real-Time Dispatching of Rubber Tired Gantry Cranes in Container Terminals MAR 2008 57 pages
Authors:  Bradley S. McNary; NAVAL POSTGRADUATE SCHOOL MONTEREY CA
The full text of this report is available for sale.Within the past 50 years containerization and globalization have driven a change from small container terminals to large container terminals that need efficient logistic models to keep up with the significant growth in container traffic. Efficiently managing of rubber tired gantry cranes and planning container placement within the terminal are two ways to increase the overall efficiency of a terminal. In this thesis, we combine these strategies in a real-time ...


ELINT Signal Processing Using Choi-Williams Distribution on Reconfigurable Computers for Detection and Classification of LPI Emitters MAR 2008 104 pages
Authors:  Teresa L. O. Upperman; NAVAL POSTGRADUATE SCHOOL MONTEREY CA
The full text of this report is available for sale.This thesis documents the use of the SRC-6 Reconfigurable Computer for use in analyzing low probability of intercept (LPI) signals using the Choi-Williams distribution. The SRC-6 is a reconfigurable computer manufactured by SRC Computers, Inc. which allows the user to tailor both the software and the hardware to a specific task. This increases the speed at which the task can be accomplished making it useful for applications in electronic intelligence ...


Implementation of a Cyclostationary Spectral Analysis Algorithm on an SRC Reconfigurable Computer for Real-Time Signal Processing MAR 2008 124 pages
Authors:  Gary J. Upperman; NAVAL POSTGRADUATE SCHOOL MONTEREY CA
The full text of this report is available for sale.This thesis describes a near-real-time method of detecting low probability of intercept (LPI) emissions. A cyclostationary spectral analysis algorithm developed by the Center for Joint Services Electronic Warfare at the Naval Postgraduate School was implemented on the SRC-6 reconfigurable computer. This thesis is part of a larger project investigating the use of the SRC-6 for electronic intelligence detection and processing. Cyclostationary processing transforms a received signal into a frequency-cycle frequency ...


The Maryland Large-Scale Integrated Neurocognitive Architecture MAR 2008 50 pages
Authors:  J. Reggia; M. Tagamets; J. Contreras-Vidal; D. Jacobs; S. Weems; W. Naqvi; C. Yang; MARYLAND UNIV COLLEGE PARK
The full text of this report is available for sale.Recent progress in neural computation, high performance computing, neuroscience and cognitive science suggests that an effort to produce a general-purpose, adaptive machine intelligence is likely to yield a qualitatively more powerful system than those currently existing. Here we outline our progress in developing a framework for creating such a large-scale machine intelligence, or neurocognitive architecture that is based on the modularity, dynamics and plasticity of the human brain. We successfully ...


Trust in Integrated Circuits MAR 2008
Authors:  Dean R. Collins; DEFENSE ADVANCED RESEARCH PROJECTS AGENCY ARLINGTON VA MICROSYSTEMS TECHNOLOGY OFFICE
The full text of this report is not available and therefore is not for sale. This information is provided for reference purposes only.DARPA's TRUST in Integrated Circuits program is directed at ensuring trust in integrated circuits that are designed and fabricated under untrusted conditions. This issue has been identified in a recent Defense Science Board study [1] and the problems described in the study are becoming more acute. The majority of Integrated Circuits (ICs) used in complex modern military systems are made off-shore. Field Programmable Gate Arrays (FPGA s) are the dominate ...


DoD M & S Governance: Vision, Implementation, Progress: The M & S Roadmap to Success. DoD M&S Steering Committee Chairman's Presentation Mar-2008 15 pages
Authors:  JOINT CHIEFS OF STAFF WASHINGTON DC MODELING AND ANALYSIS DIV
The full text of this report is available for sale.This briefing discusses the challenge to make the value of modeling and simulation to the military known to others in order to garner and keep support and funding. It puts forth DoD's envisioned end-states.


An Investigation of Communications Architecture Impact on Combat Effectiveness Using the Naval Simulation System MAR 2008 75 pages
Authors:  Peter C. Hakewessell; NAVAL POSTGRADUATE SCHOOL MONTEREY CA
The full text of this report is available for sale.This research study evaluates the ability of the Naval Simulation System (NSS) to model how changes in communication architecture for a given scenario contribute to combat effectiveness. The scenario used for this study models communication capability associated with the Marine Corps Warfighting Lab, Sea Viking 06 distributed operations scenario using the NSS. In addition, an evaluation of alternative system configurations in the communication structure is obtained in order to determine ...


A Survey of Mobile and Wireless Technologies for Augmented Reality Systems (Preprint) FEB 2008
Authors:  George Papagiannakis; Gurminder Singh; Nadia Magnenat-Thalmann; NAVAL POSTGRADUATE SCHOOL MONTEREY CA CENTER FOR THE STUDY OF MOBILE DEVICES AND COMMUNICATION
The full text of this report is not available and therefore is not for sale. This information is provided for reference purposes only.Recent advances in hardware and software for mobile computing have enabled a new breed of mobile AR systems and applications. A new breed of computing called augmented ubiquitous computing has resulted from the convergence of wearable computing, wireless networking and mobile AR interfaces. In this paper we provide a survey of different mobile and wireless technologies and how they have impact AR. Our goal is to place them into different ...


CrossTalk: The Journal of Defense Software Engineering. Volume 21, Number 1 01-Jan-2008 33 pages
Authors:  Edmond Schonberg; Lew Priven; Roger Stewart; Christopher Bohn; Jeffrey A Ingalsbe; Dan Shoemaker; Nancy R Mead; Rayford B Vaughn; Jeffrey C Carver; Lulu He; Lyle N Long; Robert B Dewar; SOFTWARE TECHNOLOGY SUPPORT CENTER HILL AFB UT
The full text of this report is available for sale.CONTENTS: 1) The Critical Need for Software Engineering Education by Dr. Lyle N. Long: Long describes the need for more dedicated software engineering educational programs and professional software engineering certification programs in the United States. 2) Using Inspections to Teach Requirements Validation by Lulu He, Dr. Jeffrey C. Carver, and Dr. Rayford B. Vaughn: This article describes an experiment conducted in a graduate-level requirements engineering course to provide students a ...


Hybrid Architectures for Evolutionary Computing Algorithms JAN 2008 158 pages
Authors:  Daniel J. Burns; AIR FORCE RESEARCH LAB ROME NY INFORMATION DIRECTORATE
The full text of this report is available for sale.This report documents the results of an in-house project aimed at identifying, developing and evaluating applications of evolutionary computing methods to hard optimization problem test cases on a single PC computer, a cluster of computers, and hardware FPGA platforms. We surveyed the evolutionary computing literature and chose to focus on the Genetic Algorithm (GA). We applied the GA to Non-Linear Coupled Ordinary Differential Equation (ODE) Parameterization, the DNA Code Word ...


Integration of Marine Mammal Movement and Behavior into the Effects of Sound on the Marine Environment Jan-2008 5 pages
Authors:  Dorian S Houser; BIOMIMETICA SANTEE CA
The full text of this report is available for sale.Integration of the Marine Mammal Movement and Behavior (3MB) model into the Effects of Sound on the Marine Environment (ESME) program contributes to the ultimate goal of creating an environmental assessment tool for activities that introduce high levels of sound into the ocean, particularly activities of the U.S. Navy. The objectives of the effort are to 1) integrate the 3MB module into the second generation model of ESME, 2) incorporate ...


A Primer on Java Obfuscation 01-Dec-2007 6 pages
Authors:  Stephen Torri; Derek Sanders; Drew Hamilton; Gordon Evans; AUBURN UNIV AL DEPT OF COMPUTER SCIENCE AND SOFTWARE ENGINEERING
The full text of this report is available for sale.Java is not a secure language and its increasing use puts sensitive information at risk. While the authors do not recommend Java software that involves sensitive information, the current reality is that Java is used in these applications. To address this reality, this article discusses Java obfuscation techniques.


Abstract Machines for Polymorphous Computing DEC 2007 57 pages
Authors:  Stephen Crago; UNIVERSITY OF SOUTHERN CALIFORNIA LOS ANGELES
The full text of this report is available for sale.The Abstract Machines for Polymorphous Computing (AMP) project made important contributions to the understanding of the programming of polymorphous computing architectures. Polymorphous architectures are a promising technology for exploiting explicit on-chip parallelism, which the microprocessor industry has recognized is necessary for the survival of the industry. The AMP project developed software tools to explore programming methodologies for polymorphous architectures, including Morphware. The AMP project mapped application to polymorphous architectures and ...


Practical Verification & Safeguard Tools for C/C++ NOV 2007
Authors:  F. Michaud; R. Carbone; DEFENCE RESEARCH AND DEVELOPMENT CANADA VALCARTIER (QUEBEC)
The full text of this report is not available and therefore is not for sale. This information is provided for reference purposes only.This document is the final report of an activity that took place in 2005-2006. The goal of this project was first to identify common software defects related to the use of the C and C++ programming languages. Errors and vulnerabilities created by these defects were also investigated, so that meaningful test cases could be created for the evaluation of best-of-breed automatic verification tools. Finally, when relevant, best practices were inferred ...


MAJIC: A Java Application for Controlling Multiple, Heterogeneous Robotic Agents SEP 2007 157 pages
Authors:  Gregory P. Ball; NAVAL POSTGRADUATE SCHOOL MONTEREY CA
The full text of this report is available for sale.Current capability to command and control a team of heterogeneous robotic agents is limited by proprietary command formats and operating systems. A specific challenge in this context is the specification, the programming, and the testing of software for such a wide variety of mobile robot teams. This work explores the applicability of an application program interface (API), called the Multi-Agent Java Interface Controller (MAJIC), that supports command, control, and coordination ...


Breast Cancer Prevention by Inducing Apoptosis in DCIS Using Breast Ductal Lavage SEP 2007 11 pages
Authors:  Patrick P. Koty; WAKE FOREST UNIV WINSTON-SALEM NC
The full text of this report is available for sale.Current prevention focuses on oral administration of chemopreventive agents which decreases breast cancer incidence but increases the risk for secondary treatment-induced disease and may not be effective in preventing those lesions that are estrogen receptor (ER) negative. We hypothesize that programmed cell death is dysregulated in premalignant breast cells which permits these cells to avoid cell death. Our studies indicate the ductal carcinoma in situ cell line DCIS3A overexpresses the ...


Search Techniques for Multi-Objective Optimization of Mixed-Variable Systems Having Stochastic Responses SEP 2007 153 pages
Authors:  Jennifer G. Walston; AIR FORCE INST OF TECH WRIGHT-PATTERSON AFB OH GRADUATE SCHOOL OF ENGINEERING AND MANAGEMENT
The full text of this report is available for sale.A research approach is presented for solving stochastic, multi-objective optimization problems. First, the class of mesh adaptive direct search (MADS) algorithms for nonlinearly constrained optimization is extended to mixed variable problems. The resulting algorithm, MV-MADS, is then extended to stochastic problems (MVMADS-RS), via a ranking and selection procedure. Finally, a two-stage method is developed that combines the generalized pattern search/ranking and selection (MGPS-RS) algorithms for single-objective, mixed variable, stochastic problems ...


CrossTalk: The Journal of Defense Software Engineering. Volume 20, Number 7 01-Jul-2007 33 pages
Authors:  Dean Nathans; Donald R Stephens; Robert F Dillingham; Thomas J Taylor; Clay Robinson; Kristopher L Strance; David Zaharchek; Richard Aldrich; Thomas Lam; Carol Macha; Ann H Kim; Linton II; Wells; John J Grimes; James E Cartwright; Michael Todd; SOFTWARE TECHNOLOGY SUPPORT CENTER HILL AFB UT
The full text of this report is available for sale.The late Edward R. Murrow once said that television is only lights and wires in a box unless we enable the technology with value-added information. In the world of cyberspace, our culture must move beyond form and format to embrace change. Culture change is the only way to enable information collaboration that adds true value to the lights and wires of our systems. It is the basic price of admission ...


GL Studio Brings Realism to Aircraft Cockpit Simulator Displays 01-Jun-2007 4 pages
Authors:  Kim Stults; 580TH SOFTWARE MAINTENANCE SQUADRON (580 SMXS) ROBINS AFB GA
The full text of this report is available for sale.Testing operational flight programs (OFPs) for aircraft requires that the user be able to enter data and generate output via a graphical user interface (GUI). Desiring to enhance the realism for the test team and upgrade the outdated software, we began the search for a new tool. A new commercial off-the-shelf (COTS) product was selected and a success story unfolded. This article presents that story.


Calculating Required Substructure Damping to Meet Prescribed System Damping Levels JUN 2007 93 pages
Authors:  Wendel D. Penetrante; NAVAL POSTGRADUATE SCHOOL MONTEREY CA DEPT OF MECHANICAL AND ASTRONAUTICAL ENGINEERING
The full text of this report is available for sale.Structural synthesis is a method of calculating the transient dynamic response of an assemblage of substructures without explicitly assembling and solving a combined system model. While significant computational advantages are provided by this method, the modal parameters of the combined system are not explicitly calculated. Hence, a method is needed to allow the a priori determination of the substructure damping levels such that the synthesized system damping is within user-prescribed ...


CrossTalk: The Journal of Defense Software Engineering. Volume 20, Number 3, March 2007 01-Mar-2007 33 pages
Authors:  SOFTWARE TECHNOLOGY SUPPORT CENTER HILL AFB UT
The full text of this report is available for sale.With all the current efforts to secure software, our nation still encounters attacks. It is estimated that 90 percent of reported security incidents result from exploits against defects in the software design or code. This is especially troubling because many of the vulnerabilities that enable these attacks can be prevented with the use of solid software engineering principles. Given that, why do we still have difficulty ensuring the integrity of ...


Intelligent Therapeutics and Metabolic Programming Through Tailormade, Ligand-Controlled RNA Switches 05 FEB 2007 7 pages
Authors:  Christina D. Smolke; CALIFORNIA INST OF TECH PASADENA
The full text of this report is available for sale.Cells employ sensor biomolecules to dynamically evaluate their environments and trigger appropriate metabolic responses. The ability to program cells with engineered molecules that sense structural and chemical events and translate these events to controlled cellular behavior is a critical technology for challenges present in medical research and biotechnology. Recent studies have demonstrated the prevalence and diversity of nucleic acids that function as sensors and regulators of gene expression. Recent efforts ...


Semantics and Pragmatics of Real-Time Maude 01-Jan-2007
Authors:  Jose Meseguer; Peter C Olveczky; OSLO UNIV (NORWAY) DEPT OF INFORMATICS
The full text of this report is not available and therefore is not for sale. This information is provided for reference purposes only.At present, designers of real-time systems face a dilemma between expressiveness and automatic verification: if they can specify some aspects of their system in some automaton-based formalism, then automatic verification is possible; but more complex system components may be hard or impossible to express in such decidable formalisms. These more complex components may still be simulated; but there is then little support for their formal analysis. The main goal of ...


UAV Scheduling via the Vehicle Routing Problem with Time Windows (Preprint) JAN 2007 17 pages
Authors:  Amanda L. Weinstein; Corey Schumacher; AIR FORCE RESEARCH LAB WRIGHT-PATTERSON AFB OH AIR VEHICLES DIRECTORATE
The full text of this report is available for sale.In an urban environment, multiple small unmanned aerial vehicles (UAVs) may be utilized to locate, surveil, or attack various targets. Whatever the task, the air vehicles must cooperate by efficiently communicating with each other and optimally assigning each UAV to the appropriate task at the appropriate target and at the appropriate time. In this paper, a vehicle assignment algorithm is developed using a mixed integer linear program (MILP) to find ...


Integration of Marine Mammal Movement and Behavior into the Effects of Sound on the Marine Environment Jan-2007 4 pages
Authors:  Dorian S Houser; BIOMIMETICA SANTEE CA
The full text of this report is available for sale.Integration of the Marine Mammal Movement and Behavior (3MB) model into the Effects of Sound on the Marine Environment (ESME) program contributes to the ultimate goal of creating an environmental impact assessment tool for Navy acoustic activities in the ocean. The objectives of the effort are to 1) integrate the 3MB module into the second generation model of ESME, 2) incorporate the influence of bathymetric features on simulated marine mammal ...


Reducing Risk by Managing Software Related Failures in Networked Control Systems DEC 2006
Authors:  Girish Baliga; Scott Graham; Carl A. Gunter; P. R. Kumar; AIR FORCE INST OF TECH WRIGHT-PATTERSON AFB OH
The full text of this report is not available and therefore is not for sale. This information is provided for reference purposes only.Managing risk is a central problem in the design and operation of networked control systems, and due to the increasing role and growing complexity of software in such systems, managing software related failures is becoming a central challenge. Even simple programming errors can cause catastrophic failures. Hence, it is vital to contain risks due to software related failures in such systems. Our main thesis is that most software related failures ...


The Role of c-FLIP(L) in Regulating Apoptotic Pathways in Prostate Cancer DEC 2006 103 pages
Authors:  Aria F. Olumi; BETH ISRAEL DEACONESS MEDICAL CENTER BOSTON MA
The full text of this report is available for sale.Abnormalities in programmed cell death (apoptosis) machinery play a crucial role in initiation progression and metastasis of prostate cancer. Therefore molecules that initiate pro-apoptotic pathways are excellent therapeutic agents in prostate cancer. However some prostate cancer cells develop resistance to pro-apoptotic agents. In this proposal we are examining the regulatory mechanisms of c-FLIP(L) which is an important modular of apoptosis in prostate cancer.


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