| Prairie View A&M/Baylor College of Medicine SMART Summer Undergraduate Prostate Cancer Research Project |
Apr-2009 |
8 pages |
| Authors:
Nancy L Weigel; B G Slaughter; BAYLOR COLL OF MEDICINE HOUSTON TX
|
 | The goal of this project is to encourage undergraduates to enter careers in prostate cancer research. This project involves BCM faculty presentations at Prairie View A & M University and a 9 week summer prostate cancer research experience at BCM for up to 5 undergraduates/year from PVAMU (3 in 2006; 4 in 2007 and 2008). Participants attended a weekly research discussion group focused on prostate cancer. Students make PowerPoint presentations ... |
|
| Chemical/Radiation Hormesis Database, Evaluation of Hormetic Mechanisms and their Biomedical and Risk Assessment Implications |
MAR 2008 |
8 pages |
| Authors:
Edward J. Calabrese; MASSACHUSETTS UNIV AMHERST SCHOOL OF PUBLIC HEALTH
|
| This project assessed the biomedical and toxicological literature for evidence of hormesis, its frequency in the literature and its underlying mechanistic foundation. This work was supported by the continued development of the hormesis database and the conduct of a high level international conference on hormesis held annually. Particular focus was given to the area of neuroscience and hormesis in the literature assessment. Fourteen manuscripts concerning hormesis and neuroscience have been ... |
|
| Subcellular Responses to Narrowband and Wideband Radiofrequency Radiation |
15 FEB 2008 |
52 pages |
| Authors:
Karl H. Schoenbach; Charles C. Tseng; OLD DOMINION UNIV RESEARCH FOUNDATION NORFOLK VA
|
| The interest in subcellular effects of radiofrequency radiation has led to the establishment of a Multidisciplinary University Research Initiative (MURI) with scientists from six academic institutions (Old Dominion University, Eastern Virginia Medical School, Massachusetts Institute of Technology, Washington University, University of Wisconsin and University of Texas Health Science Center) participating. The ODU-led MURI worked closely with its sister MURI, led by Purdue Calumet University. The research work in the ODU ... |
|
| Text Mining the Biomedical Literature |
05 NOV 2007 |
381 pages |
| Authors:
Ronald N. Kostoff; OFFICE OF NAVAL RESEARCH ARLINGTON VA
|
| Text mining of the biomedical literature provides patterns of relationships among concepts, people, and institutions, offering enhanced medical/technical intelligence unobtainable by other means. This report describes myriad text mining capabilities. Section 1 covers biomedical knowledge management, the role of text mining in knowledge management, and describes the cultural changes and global agreements required to allow the full power and capabilities of text mining to be utilized. The next two sections ... |
|
| Literature-Related Discovery: A Review |
05 NOV 2007 |
59 pages |
| Authors:
Ronald N. Kostoff; Joel A. Block; Jeffrey L. Solka; Michael B. Briggs; Robert L. Rushenberg; Jesse A. Stump; Dustin Johnson; Terence J. Lyons; Jeffrey R. Wyatt; OFFICE OF NAVAL RESEARCH ARLINGTON VA
|
| Discovery in science is the generation of novel, interesting, plausible, and intelligible knowledge about the objects of study. Literature-related discovery (LRD) is the linking of two or more literature concepts that have heretofore not been linked to produce novel interesting, plausible, and intelligible knowledge (i.e., potential discovery). Two major variants of LRD are open discovery systems (ODS), where one starts with a problem and generates a potential solution (or vice ... |
|
| Static and Dynamic Magnetic Response in Ferrofluids |
30 OCT 2007 |
12 pages |
| Authors:
Hariharan Srikanth; UNIVERSITY OF SOUTH FLORIDA TAMPA
|
| Ferrofluids are technologically important for a variety of applications ranging from biomedicine, hydraulics, to power generation. They are also model systems for the investigation of physics of relaxation phenomena in magnetic nanoparticles. We have done systematic DC and AC magnetization studies of ferrofluids composed of Fe3O4 and CoFe2O4 nanoparticles (mean size 14 nm) suspended in hexane and dodecane, respectively. The blocking temperature was just above (hexane) and much below (dodecane) ... |
|
| Nitric Oxide Generating Polymeric Coatings for Subcutaneous Glucose Sensors |
OCT 2007 |
11 pages |
| Authors:
Mark E. Meyerhoff; MICHIGAN UNIV ANN ARBOR
|
| Heretofore efforts to develop implantable sensors for real-time clinical monitoring of glucose subcutaneously (SQ) in diabetic patients have been hindered by the unreliable analytical results owing largely to biocompatibility problems induced by sensor implantation (e.g. inflammatory/foreign body response). The goal of this research program is to explore and optimize the chemistries required to fabricate implantable amperometric glucose sensors with outer polymeric coatings that slowly generate low levels of nitric oxide ... |
|
| Molecular Imaging With Quantum Dots Probing EMT and Prostate Cancer Metastasis in Live Animals |
OCT 2007 |
57 pages |
| Authors:
Leland W. K. Chung; EMORY UNIV ATLANTA GA
|
| Despite the development of various animal and tissue culture models for the study of human prostate cancer growth and metastasis, there is no non-invasive model that provides real-time information on the behavior of prostate cancer cells in the prostate or at distant sites. The goal of this application is to devise a highly sensitive and specific nanotechnology- based molecular imaging technique to detect prostate cancer growth locally and at distant ... |
|
| International Assessment of Research and Development in Brain-Computer Interfaces. WTEC Panel Report |
OCT 2007 |
235 pages |
| Authors:
Theodore W. Berger; John K. Chapin; Greg A. Gerhardt; Dennis J. McFarland; Jose C. Principe; Walid V. Soussou; Dawn M. Taylor; Patrick A. Tresco; WORLD TECHNOLOGY EVALUATION CENTER INC BALTIMORE MD
|
| Brain-computer interface (BCI) research deals with establishing communication pathways between the brain and external devices. BCI systems can be broadly classified depending on the placement of the electrodes used to detect and measure neurons firing in the brain: in invasive systems, electrodes are inserted directly into the cortex; in noninvasive systems, they are placed on the scalp and use electroencephalography or electrocorticography to detect neuron activity. This WTEC study was ... |
|
| Chapter 9 - Neurotoxicological Interactions with Physical and Psychological Stressors |
SEP 2007 |
27 pages |
| Authors:
Karl Friedl; Stephen Grate; Susan Proctor; ARMY RESEARCH INST OF ENVIRONMENTAL MEDICINE NATICK MA THERMAL AND MOUNTAIN MEDICINE DIVISION
|
| Over the past deade, the U.S. DoD invested >150M to investigate undiagnosed Gulf War Illness (GWI) and more than twice that amount in clinical management and related efforts with regard to the same issues. The research produced important new understanding of post-deployment health issues and potentially hazardous occupational, materiel, and environmental exposures. Gulf War Illnesses issues also created a new awareness of important neuropsychological and neurotoxicological interactions which were not ... |
|
| Fatigue in Military Operational Environments: An Annotated Bibliography |
JUL 2007 |
76 pages |
| Authors:
Nita L. Miller; Lawrence G. Shattuck; Panagiotis Matsangas; NAVAL POSTGRADUATE SCHOOL MONTEREY CA
|
| Research involving sleep and fatigue in military operations has been conducted for many years. Indeed, following nearly every major military engagement or conflict, reports are published which detail the effects of sleep deprivation on human performance. Unfortunately, many of these reports never make it to the scientific literature, and are published instead as technical reports. Following an extensive search of all available data sources including open scientific journals and electronic ... |
|
| Summer Undergraduate Fellowships in Breast Cancer Research |
01 MAY 2007 |
8 pages |
| Authors:
Barbara A. Christy; TEXAS UNIV HEALTH SCIENCE CENTER AT SAN ANTONIO
|
| The aim of this grant was to support a summer training program for undergraduate students interested in biomedical research, especially cancer-related research. The students selected for the program participated in cancer-related basic research for a 10-week summer period in the Department of Molecular Medicine, University of Texas Health Science Center at San Antonio. Each student was assigned a faculty mentor and placed in a laboratory, depending on their expressed interests. ... |
|
| The Role of Telomeric Repeat Binding Factor 1 (TRF1) in Telomere Maintenance and as a Potential Prognostic Indicator in Human Breast Cancer |
APR 2007 |
19 pages |
| Authors:
Kimberly S. Bulter; Jeffrey K. Griffith; ALBUQUERQUE UNIV NM
|
| The aims of this study are to (i) determine the relationships between the telomere binding protein Telomere Repeat Binding Factor I (TRFI) and other telomere binding prnteins (ii) establish the potential of TRFI as a surrogate marker for telomere content (TC) and as a potential clinical marker and (iii) characterize the relationship between of the telomere binding protein TRFI and TC. Through examining the role of TRFI in telomere length ... |
|
| Transurethral Ultrasound Diffraction Tomography |
MAR 2007 |
48 pages |
| Authors:
Matthias C. Schabel; UTAH UNIV SALT LAKE CITY
|
| The potential for cost-effective tomographic imaging using ultrasound continues to be confronted with difficulties arising from the computational complexity of fully three-dimensional object reconstruction in the diffraction regime. Development of fast and accurate forward and inverse models for ultrasound propagation in the biomedical frequency range of 1-10 MHz is essential for diffraction tomography to be a practical imaging modality. We have implemented a flexible, object-oriented simulation system in MATLAB for ... |
|
| U.S. National Science Foundation: An Overview |
24 JAN 2007 |
|
| Authors:
Christine M. Matthews; LIBRARY OF CONGRESS WASHINGTON DC CONGRESSIONAL RESEARCH SERVICE
|
 | The National Science Foundation (NSF) was created by the National Science Foundation Act of 1950, as amended (P.L. 81-507). The NSF has the broad mission of supporting science and engineering in general and funding basic research across many disciplines. The agency provides support for investigator-initiated, merit-reviewed, competitively selected awards, state-of-the-art tools, and instrumentation and facilities. The majority of the research supported by the NSF is conducted at U.S. colleges and ... |
|
| Efforts and Programs of the Department of Defense Relating to the Prevention, Mitigation, and Treatment of Blast Injuries |
Jan-2007 |
55 pages |
| Authors:
DEPARTMENT OF DEFENSE WASHINGTON DC
|
| Section 256 of the National Defense Authorization Act for Fiscal Year 2006, Public Law 109-163, provides that the Secretary of Defense shall submit a report on the efforts and programs of the Department of Defense (DoD) relating to the prevention, mitigation, and treatment of blast injuries. The report is to include the following elements of information: 1. A description of the activities undertaken under this section during the 2 years ... |
|
| Nitric Oxide Generating Polymeric Coatings for Subcutaneous Glucose Sensors |
OCT 2006 |
8 pages |
| Authors:
Mark E. Meyerhoff; MICHIGAN UNIV ANN ARBOR
|
| Heretofore, efforts to develop implantable chemical sensors for real-time clinical monitoring of glucose subcutaneously (SQ) in diabetic patients have been stymied by the unreliable analytical results owing largely to biocompatibility problems induced by sensor implantation (e.g., inflammatory/foreign body response). The goal of this research program is to explore and optimize the chemistries required to fabricate implantable amperometric glucose sensors with outer polymeric coatings that slowly generate low levels of nitric ... |
|
| Translational Health: The Next Generation of Medicine |
SEP 2006 |
35 pages |
| Authors:
Richard J. Mural; WINDBER RESEARCH INST PA
|
| The "Translational Health - the Next Generation of Medicine" conference brought together scientists and medical professionals from across the country and Europe to present and discuss their research and clinical findings in all phases of biomolecular research including DNA sequencing, genotyping, expression analysis, protein separation and identification, and biomedical informatics analysis. This conference resulted in a greater understanding of human diseases and how through combining systems biology and high-throughput molecular ... |
|
| High Speed Vessel Medical Limited Objective Experiment, Noise Assessment and Noise Reducing Stethoscope Field Test |
26 AUG 2006 |
20 pages |
| Authors:
Joseph S. Russotti; Christopher Duplessis; NAVAL SUBMARINE MEDICAL RESEARCH LAB GROTON CT
|
| Throughout NSMRL's pursuit in making optimal use of auditory information in sonar displays, interference from airborne sound in the listening environment has been a major issue. NSMRL's success in using active noise cancellation to prevent masking by airborne sound has lead to the realization that shipboard spaces may be habitable by hearing-risk standards, but not operationally suitable for critical mission tasks. Digital sound processing has opened up the auditory detection, ... |
|
| Joint Entropy Minimization for Learning in Nonparametric Framework |
09 JUN 2006 |
|
| Authors:
Parvez Ahammad; CALIFORNIA UNIV BERKELEY DEPT OF ELECTRICAL ENGINEERING AND COMPUTER SCIENCE
|
|
| Time Delay Systems with Distribution Dependent Dynamics |
10 MAY 2006 |
15 pages |
| Authors:
H. T. Banks; Sava Dediu; Hoan K. Nguyen; NORTH CAROLINA STATE UNIV AT RALEIGH CENTER FOR RESEARCH IN SCIENTIFIC COMPUTATION
|
| General delay dynamical systems in which uncertainty is present in the form of probability measures dependent dynamics are considered. Several motivating examples arising in biology are discussed. A functional analytic framework for investigating well-posedness (existence, uniqueness and continuous dependence of solutions), inverse problems, sensitivity analysis and approximations of the measures for computational purposes is surveyed. |
|
| Command History OPNAV 5750-1, Fiscal Year 2004 |
04 MAY 2006 |
41 pages |
| Authors:
Jerry Lamb; Maria Fitzgerald; Heather Huebner; NAVAL SUBMARINE MEDICAL RESEARCH LAB GROTON CT
|
| This is the Command History, OPNAV 5750-1, for the Naval Submarine Medical Research Laboratory, for Fiscal Year 2004. This FY04 report begins October 1, 2003 and ends September 30, 2004. The previous report SR 04-01 was recorded by calendar year beginning January 1, 2003 and ending December 31, 2003, therefore, some duplication may exist. The Naval Submarine Medical Research Laboratory's (NSMRL) mission is to protect the health and enhance the ... |
|
| Summer Undergraduate Training Program in Breast Cancer Research |
MAY 2006 |
10 pages |
| Authors:
G. M. Loudon; David Riese; PURDUE UNIV LAFAYETTE IN
|
| Year 04 of the Undergraduate Training Program in Breast Cancer Research has been completed successfully. In addition to the eight students funded by this grant, two additional students were recruited and funded by the Dean of Pharmacy or by individual grants. Eight different mentors were involved. In the four years of the program, 24 of the 42 participants have been women, which are underrepresented in the biomedical research community. Students ... |
|
| Patent Reform: Issues in the Biomedical and Software Industries |
07 APR 2006 |
|
| Authors:
Wendy H. Schacht; LIBRARY OF CONGRESS WASHINGTON DC CONGRESSIONAL RESEARCH SERVICE
|
| Congress currently is considering reform of the existing patent system. This interest in patent policy reflects a recognition of the increasing importance of intellectual property to U.S. innovation. Patent ownership is perceived as an incentive to the technological advancement that leads to economic growth. As such, the number of patent applications and grants has grown significantly, as have the type and breadth of inventions that can be patented. Along with ... |
|
| The Role of Telomeric Repeat Binding Factor 1 (TRF1) in Telomere Maintenance and as a Potential Prognostic Indicator in Human Breast Cancer |
APR 2006 |
15 pages |
| Authors:
Kimberly S. Bulter; Jeffrey K. Griffith; NEW MEXICO UNIV ALBUQUERQUE
|
| The aims of this study are to (i) determine the relationships between the telomere binding protein Telomere Repeat Binding Factor i (TRF1) and other telomere binding proteins, (ii) establish the potential is TRF1 as a surrogate marker for telomere content (TC) and as a potential clinical marker and (iii) characterize the relationship between is the telomere binding protein TRF1 and TC. Through examining the role is TRF1 in telomere length ... |
|
| BotXminer: Mining Biomedical Literature with a New Web-Based Application |
21 MAR 2006 |
6 pages |
| Authors:
Uma Mudunuri; Robert Stephens; David Bruining; David Liu; Frank J. Lebeda; NATIONAL CANCER INST FREDERICK MD
|
| This paper outlines botXminer, a publicly available application to search XML-formatted MEDLINE data in a complete, object-relational schema implemented in Oracle XML DB. An advantage offered by botXminer is that it can generate quantitative results with certain queries that are not feasible through the Entrez-PubMed interface. After retrieving citations associated with user-supplied search terms, MEDLINE fields (title, abstract, journal, MeSH and chemical) and terms (MeSH qualifiers and descriptors, keywords, author, ... |
|
| A Novel Approach to Monitoring Prostate Tumor Oxygenation: Proton MRI of the Reporter Molecule Hexamethyldisiloxane |
MAR 2006 |
21 pages |
| Authors:
Weina Cui; TEXAS UNIV AT DALLAS SOUTHWESTERN MEDICAL CENTER
|
| Growing evidence iron experimental and clinical studies confirms that solid human tumors have foci of hypoxic cells, which have a profound influence on the therapeutic outcome of cancer chemotherapy and radiotherapy. A strong argument therefore exists for assessing the hypoxic traction of tumors prior to patient treatment, and to tailor this treatment accordingly. It bas been shown that there is linear relationship between R1 of hexamethyldisiloxane (HMDSO) and pO2 and ... |
|
| Office of Naval Research-Interns in Biomolecular Sciences Multi-Institutional Research Enhancement Partnership Program: Research Leadership for the 21st Century |
03 JAN 2006 |
4 pages |
| Authors:
Diana Avila; Paulinus Chigbu; Mario Garcia-Rios; James R. Wild; SAINT MARY'S UNIV OF SAN ANTONIO TX
|
| The objective of this program is to enhance the research training of undergraduate students in the biological sciences, particularly underrepresented ethnic minorities and women. The participants are from four minority-serving teaching institutions: Jackson State University (JSU), Jackson, MS; St. Mary's University (StMU), San Antonio, TX); Texas A & M International University (TAMIU), Laredo, TX; and Texas A & M University, College Station, TX (TAMU-CS). During this reporting period, 12 highly ... |
|
| Second CIMIT/TATRC Symposium on Plug-and-Play (PNP) Interoperability Medical Devices in the ORF of the Future |
JAN 2006 |
27 pages |
| Authors:
Julian M. Goldman; MASSACHUSETTS GENERAL HOSPITAL BOSTON
|
| Funding was requested for a symposium to continue the process of defining technical and clinical requirements for a Medical Device Plug-and-Play (MD PnP) interoperability standardization framework for medical devices in the Operating Room of the Future and across the continuum of healthcare. The two-day symposium convened a group of 85 medical device producers, clinical users, biomedical engineers, governmental regulators (the FDA), and standards experts to 1) educate new participants in ... |
|
| Undergraduate Training Program in Breast Cancer Research |
DEC 2005 |
6 pages |
| Authors:
Suzanne Ostrand-Rosenberg; MARYLAND UNIV BALTIMORE
|
| The goal of this Training Program is to direct talented undergraduates into careers in breast cancer research. The program, called Breast Cancer Undergraduate Research Experience (BCURE), is a joint program between The University of Maryland Baltimore County(UMBC) and the University of Maryland, Baltimore Medical School (UM,B). The centerpiece of BCURE is a full-time, 10-week summer research experience in the laboratory of an established investigator (mentor) working in breast cancer research. ... |
|
| Experimental Results of a MEMS-Based Adaptive Optics System |
DEC 2005 |
5 pages |
| Authors:
Sergio R. Restaino; G. C. Gilbreath; Don M. Payne; Jonathan R. Andrews; NAVAL RESEARCH LAB WASHINGTON DC REMOTE SENSING DIV
|
| Adaptive optics techniques have been demonstrated in both laboratory and field tests, with a great level of scientific satisfaction, especially in astronomical and surveillance communities. Such successes have sparked the interest for these techniques in other fields, like biomedical imaging and industrial applications. However, to decrease complexity and costs, both very important issues for applications other than astronomical and surveillance, new technologies have to be brought to fruition. MEMS are ... |
|
| Molecular Imaging with Quantum Dots Probing EMT and Prostate Cancer Metastasis in Live Animals |
01 OCT 2005 |
25 pages |
| Authors:
Leland W. K. Chung; EMORY UNIV ATLANTA GA
|
| Despite the development of various animal and tissue culture models for the study of human prostate cancer growth and metastasis there is no non-invasive model that provides real-time information on the behavior of prostate cancer cells in the prostate or at distant sites. The goal of this application is to devise a highly sensitive and specific nanotechnology- based molecular imaging technique to detect prostate cancer growth locally and at distant ... |
|
| High-Resolution Speckle-Free Ultrasound Imaging System - A Potential Solution for Detecting Missed Breast Cancer |
OCT 2005 |
55 pages |
| Authors:
Matthew Freedman; GEORGETOWN UNIV WASHINGTON DC MEDICAL CENTER
|
| The Imperium Inc transmission ultrasound system is a highly promising novel method for imaging the breasts. In this pilot project we worked with Imperium to advise and help them modify their existing system for non-destructive testing into one suitable for breast imaging. Technical development of the system took longer than originally anticipated. We have performed a series of physics tests. We have imaged pieces of animal tissue obtained in a ... |
|
| Processing and Development of Nano-Scale HA Coatings for Biomedical Application |
13 JUL 2005 |
|
| Authors:
Afsaneh Rabiei; Brent Thomas; NORTH CAROLINA STATE UNIV AT RALEIGH DEPT OF MATERIALS SCIENCE AND ENGINEERING
|
| Functionally graded Hydroxyapatite coating with graded Crystallinity across the thickness of the film has been processed and tested as a more effective orthopedic/dental implant coating. The present study aims to increase the service-life of an orthopedic/dental implant by creating materials that form a strong, long lasting, bond with the Ti substrate as well as juxtaposed bone. The health relatedness of the new material is to increase bonding between an implant ... |
|
| Compact Transducers and Arrays |
MAY 2005 |
121 pages |
| Authors:
Robert E. Newnham; Richard J. Meyer Jr.; A. Dogan; J. Tressler; E. Uzgur; D. Markley; A. C. Hladky-Hennion; J. Zhang; PENNSYLVANIA STATE UNIV UNIVERSITY PARK
|
| The main objective of this work is to take traditional high-power, low frequency transducers and miniaturize them to expand the operating range, reduce fabrication costs, and improve performance. This effort began with the development of the "cymbal" and "moonie" miniature flex-tensional transducers. This project improved upon the cymbal design, explored modifications and developed new designs based on other low-frequency technology, such as the hollow sphere and more complex flex-tensionals miniaturized ... |
|
| CIMIT/TATRC Symposium on Developing a Plug-and-Play Open Networking Standard for the Operating Room of the Future |
MAY 2005 |
42 pages |
| Authors:
Julian M. Goldman; MASSACHUSETTS GENERAL HOSPITAL BOSTON
|
| Medicine - and specifically, the operating room environment - has not had the benefit of standardized control and communication systems. As a result, many self-evident improvements - such as seamless data communication, medical device integration, remote device actuation, and distributed closed-loop control systems - have been precluded, and safety and economic benefits have not been realized. Funding was sought for a symposium to begin the process of defining technical and ... |
|
| Summer Undergraduate Training Program in Breast Cancer Research |
MAY 2005 |
30 pages |
| Authors:
G. M. Loudon; David Riese; PURDUE UNIV LAFAYETTE IN
|
| Year 03 of the Undergraduate Training Program in Breast Cancer Research has been completed successfully. In addition to the eight students funded by this grant, two additional students were recruited and funded by the Dean of Pharmacy. Nine different mentors were involved. In the two years of the program thus far, 13 of the 22 participants have been women, who are underrepresented in the biomedical research community. Students carried out ... |
|
| Identification of the Types, Properties, and Functional Characteristics of Telomerase Expressing Cells in Breast Cancer |
MAY 2005 |
15 pages |
| Authors:
William C. Hines; Jeffrey K. Griffith; NEW MEXICO UNIV HEALTH SCIENCES CENTER ALBUQUERQUE HEALTH SCIENCES CENTER
|
| The aims of this study are to identify the types and properties of telomerase producing cells within breast tumors, and further, to isolate these cells from breast tumors so that their biochemical and functional properties may be characterized. Through examining the role of telomerase in cancer, this project also fosters the education of the candidate through the interaction with several experts in breast cancer pathology, epidemiology, biostatistics, and clinical and ... |
|
| Spacecraft Charging Technology Conference (9th) Held in Tsukuba, Japan on 4-8 April 2005. Book of Abstracts |
Apr-2005 |
194 pages |
| Authors:
AIR FORCE RESEARCH LAB HANSCOM AFB MA SPACE VEHICLES DIRECTORATE
|
| This book of abstracts contains abstracts of papers presented at the 9th Spacecraft Charging Technology Conference Held in Tasukuba, Japan on 4-8 Apr 2005. Topics of papers include: spacecraft design, pulse acoustic technology, dielectric materials for spacecraft, solar power satellite and electrical discharge, atomic oxygen, arc propagation on space power transfer systems, hypervelocity impact to solar cells in a plasma environment, evaluation of irradiation effects on silica glass by electron-beam, ... |
|
| The Role of Telomeric Repeat Binding Factor 1 (TRF1) in Telomere Maintenance and as a Potential Prognostic Indicator in Human Breast Cancer |
APR 2005 |
16 pages |
| Authors:
|
| The aims of this study are to (i) determine the relationships between the telomere binding protein Telomere Repeat Binding Factor 1 (TRF1) and other telomere binding proteins, (ii) establish the potential of TRF1 as a surrogate marker for telomere content (TC) and as a potential clinical marker and (iii) characterize the relationship between of the telomere binding protein TRF1 and TC. Through examining the role of TRF1 in telomere length ... |
|
| A Novel Approach to Monitoring Prostate Tumor Oxygenation: Proton MRI of the Reporter Molecule Hexamethyldisiloxane |
MAR 2005 |
14 pages |
| Authors:
Weina Cui; TEXAS UNIV SOUTHWESTERN MEDICAL SCHOOL AT DALLAS
|
| Growing evidence from experimental and clinical studies confirms that solid human tumors have foci of hypoxic cells, which have a profound influence on the therapeutic outcome of cancer chemotherapy and radiotherapy. A strong argument therefore exists for assessing the hypoxic fraction of tumors prior to patient treatment, and to tailor this treatment accordingly. It has been shown that there is linear relationship between R1 of hexamethyldisiloxane (HMDSO) and pO2, and ... |
|
| Laser Fabrication and Characterization of Adhesive-Free Joints for Encapsulation of Biomedical Implant Devices |
2005 |
|
| Authors:
G. Newaz; D. G. Georgiev; A. Mian; G. Auner; H. Herfurth; R. Witte; WAYNE STATE UNIV DETROIT MI COLL OF ENGINEERING
|
| Laser-fabricated joints of sub-millimeter widths between biocompatible, dissimilar materials have the potential for applications as encapsulation of miniature implant biomedical devices. In this work, we briefly describe the laser joining method of a very promising system, polyimide/titanium-coated borosilicate glass, and present and discuss results from characterization of such laser joints by means of mechanical failure (tensile) tests, optical microscopy, X-ray photoelectron spectroscopy (XPS) and raman spectroscopy. Our results suggest the ... |
|
| Project BioShield |
27 DEC 2004 |
|
| Authors:
Frank Gottron; LIBRARY OF CONGRESS WASHINGTON DC CONGRESSIONAL RESEARCH SERVICE
|
| Many potential biological terrorism agents lack available countermeasures. President Bush proposed Project BioShield to address this need. Congress considered this proposal in S. 15 (Gregg), S. 1504 (Gregg), and H.R. 2122 (Tauzin). President Bush signed S. 15 into law on July 21, 2004 (The Project BioShield Act of 2004, P.L. 108-276). The main provisions of this law include (1) relaxing procedures for bioterrorism-related procurement, hiring, and awarding research grants; (2) ... |
|
| Neuronal Cell Patterning on Covalently Bound Protein Patterns by Micro- Contact Printing Techniques and the Functioning of Proteins Bound on Silane Monolayers |
DEC 2004 |
8 pages |
| Authors:
ChangJu Chun; James J. Hickman; Weishi Wang; Cassie Gregory; Sriman Narayanan; Matthew Poeta; UNIVERSITY OF CENTRAL FLORIDA ORLANDO
|
| Micro-patterning of neuronal cells in vitro is a critical step for studies in the fundamental biology of neuron-neuron and neuron-surface interactions. The culturing of neuronal cells on patterned self-assembled monolayers (SAMs) in some cases require further chemical modifications of the SAM surfaces to induce cell adhesion and promote neurite outgrowth. In these cases it would be important to select a negative surface modifying agent such as an extracellular matrix protein ... |
|
| Proceedings for the Army Science Conference (24th) Held on 29 November-2 December 2004 in Orlando, Florida (CD-ROM) |
DEC 2004 |
|
| Authors:
Heesung Kwon; Nasser M. Nasrabadi; Wen-Hsiung Lee; Paul D. Gader; Joseph N. Wilson; ASSISTANT SECRETARY OF THE ARMY (ACQUISITION LOGISTICS AND TECHNOLOGY) ARLINGTON VA
|
| ELECTRONIC FILE CHARACTERISTICS: 473 files; Adobe Acrobat (.PDF) and HyperText Markup Language (.HTML). PHYSICAL DESCRIPTION: 1 CD-ROM; 4 3/4 in.; 255 MB. SYSTEMS DETAIL NOTE: ABSTRACT: Over 350 manuscripts and summaries were submitted in the following technical areas: Sensors and Information Processing, IT/C4ISR, Advanced Computing and Simulation, Lethality Technologies, Unmanned Systems, Force Protection/Survivability, Advanced Materials and Manufacturing Technology, Power and Energy, Immersive Technology, Behavioral Sciences and Human Performance, Biomedical ... |
|
| Novel Non-Intrusive Trans-Dermal Remote Wireless Micro-Fluidic Monitoring System Applied to Continuous Glucose and Lactate Assays for Casualty Care and Combat Readiness Assessment |
01 SEP 2004 |
19 pages |
| Authors:
John F. Currie; Michael M. Bodo; Frederick J. Pearce; WALTER REED ARMY INST OF RESEARCH SILVER SPRING MD DEPT OF RESUSCITATIVE MEDICINE
|
| We present results on both the bio-medical engineering development of a non-intrusive, wireless, microfluidic physiological monitoring and remote transmission field system, and its performance measuring continuous glucose and lactate concentrations in the interstitial fluid of rats subjected both to glucose-stress tests, and to hemorrhagic shock. These directly address the two symposium topics of Monitoring of physiological parameters and measurement of vital signs in the field and of Medical surveillance in ... |
|
| International Symposium on Polymer Electrolytes (9th) Held in Mragowo, Poland, on August 22-27, 2004 |
27 AUG 2004 |
234 pages |
| Authors:
Zbigniew Florjanczyk; Franciszek Krok; Janusz Plocharski; WARSAW UNIV POLAND
|
| This is the Final Proceedings for the 9th Symposium on Polymer Electrolytes (ISPE 9), 22 August 2004 - 27 August 2004. This is an interdisciplinary conference. Topics include: 1) basic theory, including modeling and simulation techniques; 2) physical and electrochemical methods of characterization; 3) structural studies; 4) investigations of ion transport mechanisms; 5) new polymer electrolytes; 6) existing and expected engineering applications in electrochemical energy storage systems, fuel cells, display ... |
|
| A Training Program in Breast Cancer Research Using NMR Techniques |
JUL 2004 |
53 pages |
| Authors:
Paul C. Wang; HOWARD UNIV WASHINGTON DC
|
| This program has supported four predoctoral students (two students from the Electrical Engineering Department, one medical student and one MD/PhD student from Biochemistry) and three postdoctoral fellows. The new students have been introduced to the Biomedical NMR Laboratory and the Howard University Cancer Center. The trainees have continued to learn the theories and instrumentation behind nuclear MRI. The trainees have rotated through the mammography service in the Radiology Department to ... |
|
| Continuation of Support for the Institute for Laboratory Animal Research |
JUL 2004 |
|
| Authors:
Joanne Zurlo; NATIONAL ACADEMY OF SCIENCES WASHINGTON DC
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| ILAR is a recognized leader in developing and disseminating guidelines for laboratory animal care, breeding, and use. ILAR develops resources for identifying animal models for human diseases and physiological processes; and prepares reports on the humane and scientific use of laboratory animals. The program goal is to improve the humane and scientifically valid use of laboratory animals as well as the availability, quality and care of laboratory animals. ILAR accomplishes ... |
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| Summer Undergraduate Training Program in Breast Cancer |
MAY 2004 |
9 pages |
| Authors:
G. M. Loudon; PURDUE UNIV LAFAYETTE IN
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| Year 2002 of the Undergraduate Training Program in Breast Cancer Research has been completed successfully. In addition to the eight students funded by this grant, two additional students were recruited and funded by the Dean of Pharmacy. Nine different mentors were involved. In the two years of the program thus far, 13 of the 22 participants have been women, who are underrepresented in the biomedical research community. Students carried out ... |
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Reports by Keyword(s)
BIOMEDICINE
