| Diagnosed Eating Disorders in the U.S. Military: A Nine Year Review |
01-Sep-2008 |
16 pages |
| Authors:
Amanda J Antczak; Teresa L Brininger; ARMY RESEARCH INST OF ENVIRONMENTAL MEDICINE NATICK MA MILITARY PERFORMANCE DIV
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 | The objective of this study was to determine the incidence of three types of eating disorders (ED) -- anorexia nervosa (AN), bulimia nervosa (BN) and eating disorder not otherwise specified (EDNOS) -- diagnosed in the U.S. Military. Diagnosed cases of ED were obtained from the Defense Medical Epidemiology Database for all Service Members (SM) from 1998-2006. The percentage per year of SM with an ED diagnosis was .30%. Eating disorders ... |
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| Tumor-Secreted Autocrine Motility Factor (AMF): Causal Role in an Animal |
AUG 2006 |
6 pages |
| Authors:
John M. Chirgwin; VIRGINIA UNIV CHARLOTTESVILLE
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 | Cancer cachexia has three clinical features: I) loss of appetite (anorexia), 2) nutritional mal-absorption, and 3) muscle and fat wasting caused by tumor-stimulated factors. This project focused on muscle wasting. A number of factors have been proposed to cause cancer cachexia. Lack of progress in the area is unfortunate, given the tremendous benefit patients with advanced cancer would receive from effective treatment of cachexia to improve quality of life and ... |
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| Specific Reversible Cytostatic Protection of Normal Cells Against Chemotherapeutics in Breast Cancer Therapy |
MAR 2006 |
9 pages |
| Authors:
Benjamin B. Mull; M D ANDERSON CANCER CENTER HOUSTON TX
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 | The adverse effects of cancer chemotherapy are widely recognized. Hair loss,gastrointestinal discomfort, lethargy and anorexia are quite common. The cause for these events is the nonspecific nature of current cancer treatment agents. Cytotoxic drugs, while effective at killing proliferating tumor cells, also target normal dividing cells. It is the purpose of this study to develop a proven in vitro strategy to protect normal dividing cells using a cytostatic agent, UCN-01. ... |
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| Collective Behaviors: Mass Panic and Outbreaks of Multiple Unexplained Symptoms |
20 FEB 2002 |
4 pages |
| Authors:
Ross H. Pastel; ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK MD
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 | The general public, the mass media, and many government officials believe that the use of weapons of mass destruction (WMD) will inevitably lead to mass panic and/or mass hysteria. However, studies of disasters and wars show that disorganized flight in the presence of a real or perceived danger (i.e., mass panic) is rare. On the other hand, in a real or perceived WMD scenario, outbreaks of multiple unexplained symptoms (i.e., ... |
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| Effect of DHEA on Bone in Young Adults |
SEP 1999 |
64 pages |
| Authors:
Meryl Leboff; BRIGHAM AND WOMEN'S HOSPITAL BOSTON MA
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 | Peak bone mass is achieved during young adulthood, accompanying marked rises in gonadal and adrenal steroids E.G., DEHYDROEPIANDROSTERONE- SULPHATE, (DHEAS) and insulin-like growth factors (IGF-1). In these studies, we will test the hypothesis that DHEA increases bone mass through anabolic (e.g., IGF-1), and antiosteolytic (e.g., interleukins) mechanisms as follows: *Specific Aim I--to measure the effects of DHEA on bone and the regulation of androgens, lGF-1, ... |
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| The Female Athlete Triad: Prevalence in Military Women |
JUL 97 |
38 pages |
| Authors:
Tamara D. Lauder; MADIGAN ARMY MEDICAL CENTER TACOMA WA
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 | The female athlete triad, otherwise known as the inter-relatedness of disordered eating, amenorrhea, and osteoporosis, is an area of increasing awareness in female athletes, which has not been explored in military women. We conducted a 3 part prospective cross-sectional study to define the prevalence of eating disorders, menstrual irregularities, and the full female athlete triad in military women. A total of 423 female soldiers from the general active-duty population completed ... |
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| Sex Differences, Stress, and Military Readiness |
MAR 96 |
408 pages |
| Authors:
Frances H. Gabbay; Robert J. Ursano; A. E. Norwood; C. S. Fullerton; L. K. Sutton; UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD DEPT OF PSYCHIATRY
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 | The goal of this report is to consider the effects of stress associated with combat, deployment, contingency operations, and trauma on military women's health and performance. This volume reviews empirical and theoretical work bearing on issues of sex differences in the effects of stress on mental health and performance, and to consider ways in which knowledge of this work might assist commanders in the integration of women into an effective ... |
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| Medical Surveillance Monthly Report (MSMR). Volume 1, Number 8, November 1995 |
Nov-1995 |
13 pages |
| Authors:
Bruce H Jones; Sharon L Ludwig; Mark V Rubertone; John F Brundage; Cynthia R Towle; Vincent P Fonseca; ARMED FORCES HEALTH SURVEILLANCE CENTER SILVER SPRING MD
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 | The patient is a 48 year old army reservist who was in Port Au Prince, Haiti from May 28 through October 12, 1995. His duties as a flight engineer involved supervising loading and unloading of Chinooks for troop transport, vehicle transport, and ballot distribution (for the elections) throughout the island; consequently, he had contact with many foreign troops, including Pakistani, Bangladeshi, Argentinian, and Canadian. Despite using military-issued insect repellent regularly ... |
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| Toxicology and Pharmacology of the Chemical Warfare Agent Sulfur Mustard - A Review |
05 APR 95 |
89 pages |
| Authors:
Jack C. Dacre; Richard Beers; Max Goldman; GEO-CENTERS INC NEWTON CENTRE MA
|
 | Sulfur mustard is a poisonous chemical agent which exerts a local action on the eyes, skin and respiratory tissue with subsequent systemic action on the nervous, cardiac, and digestive and endocrine systems in man and laboratory animals causing lacrimation, malaise, anorexia, salivation, respiratory distress, vomiting, hyperexcitability, cardiac distress, and death. Sulfur mustard is a cell poison which causes disumption and impairment of a variety of cellular activities which are dependent ... |
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| Role of Cytokines in the Acute Phase Response |
19 MAY 94 |
4 pages |
| Authors:
Matthew J. Kluger; LOVELACE INSTITUTES ALBUQUERQUE NM INST OF BASIC AND APPLIED MEDICAL RESEARCH
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 | We have characterized the physiological and behavioral responses to influenza infection in mice. Studies have been run showing that ip injection of antiserum to IL-1Beta increased survival rate in influenza-infected mice, and at the same time magnified the decrease of body temperature. We hypothesize that the antiserum inactivated biological activity of the large part of IL-1Beta, an endogenous pyrogen, thereby disturbing the ratio between pyrogenic and cryogenic input on thermoregulatory ... |
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| Investigation of the Hepatotoxic and Immunotoxic Effects of the Peroxisome Proliferation Perflurodecanoic Acid |
SEP 93 |
88 pages |
| Authors:
Melinda J. Tarr; OHIO STATE UNIV COLUMBUS DEPT OF VETERINARY PATHOLOGY
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 | The effects of perfluorodeconoic acid (PFDA) on humoral, cellular, and innate immunity in Fischer 344 rats was studied at 8 days and 30 days following a single intraperitoneal injection at doses of mg/kg body weight. Effects of in vitro PFDA treatment were also determined. PFDA was found to significantly decrease IgG2 alpha production at 8 days following PFDA treatment and to cause a trend of decreased DIFI responsiveness, reflecting inhibitory ... |
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| Therapeutic Intervention Strategies for Staphylococcal Enterotoxin B-Induced Illness. |
13 MAY 1993 |
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| Authors:
Marti Jett; Robert Hunt; Thomas Boyle; Peter Gemski; WALTER REED ARMY INST OF RESEARCH WASHINGTON DC DIV OF PATHOLOGY
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 | The characteristics of Staphylococcal enterotoxin B (SEB) intoxication in monkeys and man include vomiting and diarrhea that can lead to shock and death. Experimentally in rhesus monkeys, SEB administered (Iv) caused vomiting, diarrhea, anorexia and malaise within 2-7 hr. The monkeys demonstrated no apparent illness for the following 10-20 hr; another period of mild illness occurred (for about 7 hr), then a 5 hr brief improvement. From 40-60 hr, the ... |
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| Investigation of the Hepatotoxic and Immunotoxic Effects of the Peroxisome Proliferator Perfluorodecanoic Acid |
30 APR 92 |
40 pages |
| Authors:
Melinda J. Tarr; Larry E. Mathes; OHIO STATE UNIV COLUMBUS
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 | These studies examine the immunotoxic effects 8 days and 30 days following an intraperitoneal injection of PFDA. Histologic alterations observed in lymphoid organs at 8 days following PFDA treatment were more severe than those apparent at 30 days following PFDA treatment. Relative thymus weight was decreased at both 8 and 30 days following PFDA treatment, whereas relative spleen weight was decreased only at 8 days following PFDA treatment. Proliferation in ... |
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| CCK Heptapeptide Analogs: Effect of Conformational Restrictions and Standard Modifications on Selectivity and Activity at CCK-A and CCK-B Receptors, |
1992 |
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| Authors:
Mark W. Holladay; Michael J. Bennett; Michael D. Tufano; C. W. Lin; David G. Witte; ABBOTT LABS NORTH CHICAGO IL
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 | Cholecystokinin (CCK) is a peptide hormone involved in the regulation of gall bladder contraction, pancreatic enzyme secretion, and gastric emptying. Exogenous CCK or its close analogs suppress feeding in a number of species, including man, and endogenous CCK may have a role in the normal satiety response. As part of our effort toward development of anorectic agents based on CCK, we investigated the structural and conformational requirements for activity at ... |
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| Considerations for Replacement Beverages: Fluid-Electrolyte Balance and Heat Illness |
28 FEB 89 |
18 pages |
| Authors:
Lawrence E. Armstrong; ARMY RESEARCH INST OF ENVIRONMENTAL MEDICINE NATICK MA
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 | This article emphasizes the specific need (or lack of need) for carbohydrate-electrolyte solutions, which soldiers experience during duty in hot environments. Because this article will focus on fluids and electrolytes, it is helpful to reiterate the following aspects of their reports: a) Gatorade was used in dilute form, at 2/3 (Alltz) and 1/4 (Donovan) strength, b) meals were sacrificed so that the mission could be accomplished, and c) a rigorous ... |
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| Thyroid and Biochemical/Metabolic Effects of PFDA (Perfluoro-n-decanoic Acid) |
04 JAN 88 |
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| Authors:
Albert E. Langley; WRIGHT STATE UNIV DAYTON OH DEPT OF PHARMACOLOGY
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 | Significantly greater weight loss was observed in PFDA-treated rats than in pair controlled rats. These data indicate that the wasting syndrome cannot be explained entirely by lack of food intake. Additionally, a precipitous fall in serum thyroxine was observed as early as 12 hours following PFDA. Early experiments indicated that a hypothyroid-like state resulted from PFDA treatment. PFDA induced decreases in serum thyroid hormones, anorexia, bradycardia, hypothermia, as well as ... |
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| Nutrition and Physical Performance in Military Environments |
DEC 1987 |
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| Authors:
Ira Jacobs; DEFENCE AND CIVIL INST OF ENVIRONMENTALMEDICINE DOWNSVIEW (ONTARIO)
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 | This report is a review of research findings concerning nutritional aspects of physical performance with direct relevance to the operational requirements of military personnel. Among the macronutrients providing fuel to working muscle, only carbohydrates are relatively limited in availability. Since muscle depends on carbohydrates as an energy store for high intensity exercise performance, depletion of these stores have detrimental effects on exercise performance. In contrast, there is no consistent evidence ... |
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| Airborne Induced Experimental Bordetella bronchiseptica Pneumonia in Strain 13 Guinea Pigs |
JAN 86 |
25 pages |
| Authors:
Creighton J. Trahan; Edward H. Stephenson; John W. Ezzell; William C. Mitchell; ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK MD
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 | Strain 13 guinea pigs were evaluated as an animal model to study the molecular interactions of Bordetella sp and to evaluate the efficacy of B. bronchiseptica bacterins in inducing a protective immune response. When guinea pigs were exposed to small particle aerosols of varying concentrations of virulent B. bronchiseptica, a spectrum of disease was produced that ranged from inapparent to fulminant. Clinical signs began by day 4 after exposure, and ... |
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| Nuclear Weapon Effect Research at PSR (Pacific-Sierra Research Corporation) - 1983. Symptomatology of Acute Radiation Effects in Humans after Exposure to Doses of 75 to 4500 Rads (cGy) Free-in-Air |
31 AUG 84 |
67 pages |
| Authors:
Siegmund J. Baum; Robert W. Young; George H. Anno; H. R. Withers; PACIFIC-SIERRA RESEARCH CORP LOS ANGELES CA
|
 | This report distills from available data descriptions of typical human symptoms in reaction to prompt ionizing radiation in the dose range 75 to 4500 rads (cGy) free-in-air. The descriptions correlate symptoms with dose and time over the acute postexposure period of six weeks. Their purpose is to provide an empirical base for estimating combat troop performance after a nuclear weapon attack. We divide the dose range of interest into eight ... |
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| Acute Infectious Disease |
23 MAR 1984 |
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| Authors:
W. R. Beisel; ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK MD
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 | The development of acute generalized infectious illnesses and serious inflammatory reactions is accompanied by the occurrence of a large number of interrelated host defensive measures. These constitute the generalized acute- phase response to infection, inflammatory states, or complex trauma. These responses include the development of fever and hypermetabolism, the production of a leukocytic response, the accelerated proteolysis of skeletal muscle, the generation of free amino acids from body somatic protein ... |
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| Resume of the Discussion Concerning the Nutritional Consequences of Infection. |
20 AUG 1976 |
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| Authors:
William R. Beisel; ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FREDERICK MD
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 | The discussion of papers presented during the session on Nutritional Consequences of Infection covered topics which included the changing concepts of 'body wasting' during acute and chronic infections, the effects of fever, reduced dietary intake, gastrointestinal disturbances, and the role of various acute-phase reactant proteins and endogenous mediator substances produced by host cells. Comments were made concerning the response of various enzymes and amino acids during an infectious process. The ... |
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| Studies on Canine Dirofilariasis. |
MAY 1974 |
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| Authors:
W. F. Hutchinson; R. W. Intermill; MISSISSIPPI UNIV JACKSON SCHOOL OF MEDICINE
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 | The etiologic agent of canine heartworm is a nematode, Dirofilaria immitis. Once the infective larvae enter the normal definitive host, a dog, an intermediate growth phase ensues. Symptoms and signs of infection in the dog can vary according to worm load. Symptomatology normally includes a lack of endurance, anorexia and labored breathing. Specific signs may include a chronic cough, dry hair coat, loss of weight and hematuria. The research reported ... |
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