| State-to-State Reactive and Collisional Dynamics of Atmospheric Species |
NOV 96 |
16 pages |
| Authors:
David J. Nesbitt; COLORADO UNIV AT BOULDER
|
 | The AFOSR research efforts over the past three years have achieved the following goals. (1) We have now completed state to state scattering measurements for CH4, H2O and HF with rare gas (Ar, Ne and He) collision partners, based on direct infrared absorption in crossed molecular beams. (2) Hot atom state to state scattering of Cl with HCl has been studied using high resolution Dopplerimetric techniques to obtain both differential ... |
|
| Determination of Patients' Breast Tumor-Specific Immunity and Its Enhancement with In Vitro Stimulation and Gene Therapy |
OCT 96 |
28 pages |
| Authors:
Elizabeth A. Repasky; HEALTH RESEARCH INC BUFFALO NY
|
| During the second year of our Army support, we have made substantial progress toward isolating tumor-reactive lymphocytes, and toward developing a model system by which various notions regarding immunotherapy can be tested. All of this most recent work depended completely upon the development of a SCID mouse animal model which sustains the growth of many patients' primary breast tumors, and the expansion of this model to include a larger number ... |
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| Development of an Inverse Technique to Estimate the Ultrasound Field during Chest Wall and Breast Hyperthermia |
AUG 1996 |
36 pages |
| Authors:
Charles L. Thomas; UTAH UNIV SALT LAKE CITY
|
| It is the goal of this research to provide improved numerical modeling of ultrasound propagation through breast tissue and the post-mastectomy chest wall for use in patient treatment planning of hypethermia cancer treatments. With this improved model the clinician can plan an ultrasound hypothermia treatments so as to produce the required thermal dose while minimizing patient pain due to excessive temperature or ultrasound-tissue interactions. A clinical system is being constructed ... |
|
| AFRRI Report Third - Fourth Quarters 1996 |
96 |
57 pages |
| Authors:
ARMED FORCES RADIOBIOLOGY RESEARCH INST BETHESDA MD
|
| Table contents: Effect of chloral hydrate on in vivo KCl-induced striatal dopamine release in the rat. Effect of ionizing radiation on in vivo striatal release of dopamine in the rat. Transient and persistent experimental infection of nonhuman primates with Helicobacter pylori: Implications for human disease. Indomethacin attenuation of radiation-induced hyperthermia does not modify radiation-induced motor hypoactivity. Behavioral toxicity and radioprotective efficacy of WR-15l327 in combination with adenosine receptor antagonists. Chromatographic ... |
|
| In Vivo Measurement of Na+ and K+ ions Using ion-Selective Electrodes |
05 JUN 95 |
28 pages |
| Authors:
Anthony I. Osagie; Candace B. Matthew; Stephen P. Mullen; ARMY RESEARCH INST OF ENVIRONMENTAL MEDICINE NATICK MA
|
| Measurement of circulating levels of the electrolytes Na+ and K+ is integral to physiological studies of hyperthermia, dehydration, and nutrition. Current methods require removal of blood samples for later analysis. In small animals such as rats the volume removed can alter experimental results. In this study, cannulae were surgically implanted in a jugular vein and carotid artery of rats. Using ion selective electrodes and a flow-through sampling chamber of our ... |
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| A 3-D Finite Difference Time Domain Investigation of Microwave Propagation Through Inhomogeneous Biological Materials |
DEC 94 |
158 pages |
| Authors:
David B. Dunn Jr; AIR FORCE INST OF TECH WRIGHT-PATTERSON AFB OH SCHOOL OF ENGINEERING
|
| This paper extends past analysis of an optimal source distribution around a homogeneous sphere of muscle tissue by using a 3-D finite difference time domain (FDTD) scenario in which an anatomically correct human head model is irradiated. It first duplicates the analytical solution within an FDTD space using an FDTD computer code developed at Penn State University. This duplication uses a 9.45 cm radius sphere represented in an FDTD space ... |
|
| Use of Combination Thermal Therapy and Radiation in Breast Conserving Treatment of Extensive Intraductal Breast Cancer |
11 JUL 94 |
71 pages |
| Authors:
Goran K. Svensson; Everette C. Burdette; NEW ENGLAND DEACONESS HOSPITAL BOSTON MA
|
| Year 01 of this contract supports the development of a technique for treatment of breast cancer, with an Extensive Intraductal Component (EIC) or pure Ductal Carcinoma in Situ (DCIS) using thermal therapy generated from ultrasound transducers. We have studied the technical approach for these treatments using complex computer simulations. The thermal treatment of the breast will be done with the patient in prone position with the breast submerged into a ... |
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| Potassium Deficiency in Rats: Effects on Rates of Dehydration and Electrolyte Homeostasis |
1994 |
7 pages |
| Authors:
R. P. Francesconi; N. M. Leva; C. R. Johnson; R. W. Hubbard; ARMY RESEARCH INST OF ENVIRONMENTAL MEDICINE NATICK MA
|
| Three groups of rats were fed a nutritionally complete (C), potassium-deficient (-K), or potassium-supplemented (+K) diet for 28 days followed by passive exposure to a moderate heat stress (T sub amb = 31.5 deg C) until a hypohydration level of 8-9% of initial body weight was achieved. Significant (P |
|
| Predictions of Human Tolerance to Cold Water Immersion While Wearning Advanced Integrated Garment Ensembles With and Without Survival Rafts or Exogenous Heating |
30 DEC 93 |
47 pages |
| Authors:
Barry S. Shender; Jonathan Kaufman; NAVAL AIR WARFARE CENTER AIRCRAFT DIV WARMINSTER PA AIR VEHICLE AND CREW SYST EMS TECHNOLOGY DEPT
|
| US Navy interest in garments providing integrated protection against chemical agents, hyperthermia, hypobaria, and hypothermia has led to fabrication of prototype multi-purpose garments. As part of the development process, these garments need to be tested for the protection they provide against these hazards. Mathematical modeling can be used to simulate the thermal protection provided by the various garment designs and minimize laboratory testing. It can also be used to establish ... |
|
| Cellular and Molecular Level Responses After Radiofrequency Radiation Exposure, Alone or in Combination with X-rays or Chemicals |
27 JUL 92 |
94 pages |
| Authors:
Martin L. Meltz; TEXAS UNIV HEALTH SCIENCE CENTER AT SAN ANTONIO
|
| The focus of the second years' activities has been to establish, for the human 244B human lymphoblastoid cell line, selected biological effects of standard dose rate ionizing radiation (over the same low total dose range as to be used for combined microwave/ionizing radiation experiments) and hyperthermia (at the same temperature as will be used in the combined studies). Th endpoints which have been examined, and for which alterations have been ... |
|
| Effect of Protective Clothing Ensembles on Artillery Battery Crew Performance |
17 JUL 92 |
41 pages |
| Authors:
Patricia C. Szlyk; David M. Caretti; Ingrid V. Sils; Orest Zubal; Jim A. Faughn; ARMY RESEARCH INST OF ENVIRONMENTAL MEDICINE NATICK MA
|
| Performance of three 9-man crews was evaluated while firing 90 rounds in a safe and expedient manner, with swabbing of the breech after each round. Each 9-man crew fired on three non-consecutive days; the independent variable among days was the MOPP level worn (BDU vs MOPP IV vs MOPP IV with cooling). All 90 rounds were fired by all three crews when wearing BDU. Despite similar climatic conditions, 2 of ... |
|
| Investigation of the Effect of Cooling the Feet as a Means of Reducing Thermal Stress |
AUG 91 |
|
| Authors:
Sydney D. Livingstone; Richard W. Nolan; DEFENCE RESEARCH ESTABLISHMENT OTTAWA (ONTARIO)
|
 | The purpose of this investigation was to determine if cooling the feet is as effective as cooling the hands in the alleviation of heat stress. Each of six volunteers dressed in chemical warfare (CW) protective clothing, sat for 120 min in an environment of 35 deg C and then immersed his feet in a water calorimeter for 20 min. Heat lost to the calorimeter was measured at water temperatures of ... |
|
| Application of Adaptive Nulling to Electromagnetic Hyperthermia for Improved Thermal Dose Distribution in Cancer Therapy |
03 JUL 91 |
|
| Authors:
Alan J. Fenn; MASSACHUSETTS INST OF TECH LEXINGTON LINCOLN LAB
|
| Adaptive nulling is applied to the problem of generating a therapeutic thermal dose distribution in electromagnetic hyperthermia treatment of cancer. A system design concept for implementing adaptive hyperthermia is introduced. With the proposed design concept, it may be possible to maximize the applied electric field at a tumor position in th target body and simultaneously minimize or reduce the electric field at target positions where undesired high temperature regions (hot ... |
|
| Anticholinergics: Effects on Thermoregulation and Performance in Rats |
Jan-1991 |
6 pages |
| Authors:
Candace B Matthew; ARMY RESEARCH INST OF ENVIRONMENTAL MEDICINE NATICK MA
|
|
| Thermoregulatory Consequences of Resonant Microwave Exposure |
JUN 90 |
|
| Authors:
Eleanor R. Adair; JOHN B PIERCE FOUNDATION LAB NEW HAVEN CT
|
| Four experiments were conducted in which it was shown that behavioral and autonomic thermo-regulatory responses are mobilized in an orderly fashion when squirrel monkeys undergo whole-body exposure at the resonant frequency, 450 MHz. The threshold for alteration of thermo-regulatory behavior is about 3 mW/sq cm, equivalent to an SAR of nearly 2 W/kg. Behavioral responses serve to regulate the skin temperature at the normally preferred level. Because of the deep ... |
|
| Exertional Heatstroke in Soldiers: An Analysis of Predisposing Factors, Recovery Rates and Residual Heat Intolerance |
20 NOV 89 |
|
| Authors:
L. E. Armstrong; J. P. De Luca; R. W. Hubbard; E. L. Christensen; ARMY RESEARCH INST OF ENVIRONMENTAL MEDICINE NATICK MA
|
| Ten prior heat stroke patients (PH) were observed in our laboratory during a two-week protocol which measured heat acclimation ability, heat tolerance responses, fluid-electrolyte balance, thermoregulation, and blood values. Nine PH exhibited normal heat acclimation adaptations, thermoregulation, sweat gland function, whole-body sodium and potassium balance, and clinical values after exertional heatstroke. One PH (subject A) did not adapt to exercise in the heat and was defined as heat intolerant, but ... |
|
| Heatstroke Pathophysiology: The Energy Depletion Model |
12 JUN 89 |
|
| Authors:
Roger W. Hubbard; ARMY RESEARCH INST OF ENVIRONMENTAL MEDICINE NATICK MA
|
| This symposium focuses on exertional heatstroke, with emphasis on predisposing factors, clinical observations, diagnosis, treatment and recovery. The serious challenge to cardiovascular stability presented by exercise hyperthermia and some aspects of regulatory failure were reviewed in the introduction. The intent of this review, to describe how heat stress is translated into heat strain at the cellular level, is not to downplay the seriousness of the systemic condition. If we are ... |
|
| Exertional Heatstroke: An International Perspective. An Introduction: The Role of Exercise in the Etiology of Exertional Heatstroke |
12 JUN 89 |
|
| Authors:
R. W. Hubbard; ARMY RESEARCH INST OF ENVIRONMENTAL MEDICINE NATICK MA
|
| Exertional heatstroke usually occurs among healthy, fit individuals who are motivated to perform strenuous exercise because of peer pressure, discipline, or athletic competition. In fact, exertional heatstroke deaths among high school athletes in the United States (ranked only third to head and neck injuries and heart failures), and the reluctance of race directors to cancel or postpone mass participation road races during periods of severe heat and humidity, emphasize a ... |
|
| Effects of MOPP Configurations and Two Drinking Systems on Fluid Balance and Performance |
19 MAY 89 |
|
| Authors:
Patricia C. Szlyk; Ingrid V. Sils; Ralph P. Francesconi; Roger W. Hubbard; ARMY RESEARCH INST OF ENVIRONMENTAL MEDICINE NATICK MA
|
| The impact of wearing MOPP on fluid balance, thermoregulation and performance was evaluated. Fifteen male soldiers walked for 6 consecutive 50/10 min. work/rest cycles on two non-consecutive days and iodinated water (30 C) was consumed ad-lib. On one day, soldiers wore the Battle Dress Uniform (BDU) and drank from canteens; on the second day, they wore MOPP IV and drank with either the current gravity feed system (CS) or a ... |
|
| Radio Frequency (13.56 MHz) Energy Enhances Rewarming from Mild Hypothermia |
09 MAY 89 |
|
| Authors:
R. L. Hesslink; R. G. Olsen; L. D. Allen; L. D. Homer; S. B. Lewis; NAVAL MEDICAL RESEARCH INST BETHESDA MD
|
| The rate of warming after hypothermia depends on the method of rewarding. This study compared the effectiveness of radio frequency (RF) energy against hot (41 C) water immersion (HW) and an insulated cocoon (IC) for rewarming hypothermic men. Six men fasted overnight and were rewarmed for one hour after attaining a 0.5 reduction in rectal temperature (Tre). Tre and esophageal temperature (Tes) were recorded every 5 minutes with non-metallic thermal ... |
|
| Effects of Chemical Protective Clothing and Masks, and Two Drinking Water Delivery Systems on Voluntary Dehydration |
MAY 89 |
|
| Authors:
Patricia C. Szlyk; R. P. Francesconi; I. V. Sils; R. Foutch; R. W. Hubbard; ARMY RESEARCH INST OF ENVIRONMENTAL MEDICINE NATICK MA
|
| The effects of MOPP IV configuration and the M17A1 face mask and two water delivery systems (CURRENT and FIST-FLEX type) on voluntary dehydration and fluid-electrolyte balance were evaluated. Fifteen male subjects walked on a treadmill set on a flat grade at a rate of 4.02 km/hr for 50 min of each hr for up to 6 hrs. The effects of the two water delivery systems on fluid balance and temperature ... |
|
| Development of a Rapid, Noninvasive Core Temperature Measurement Device. Phase 1 |
01 MAR 89 |
|
| Authors:
Steven M. Falk; GMS ENGINEERING CORP COLUMBIA MD
|
| The rapid, noninvasive measurement of core temperature in humans is desireable since both elevated core temperature (hyperthermia) and depressed core temperature, including oral and rectal thermometry, are unacceptable for field core estimation because of both physical and cultural problems. A rapid, noninvasive means of determining core temperature would be beneficial for in field management of combat casualties, as well as in peace-time evaluations of military materiel and physical workload assessments. ... |
|
| Application of a Model of Exertional Heatstroke Pathophysiology to Cocaine Intoxication |
11 JAN 89 |
|
| Authors:
L. E. Armstrong; R. W. Hubbard; ARMY RESEARCH INST OF ENVIRONMENTAL MEDICINE NATICK MA
|
| We would like to propose a novel cellular model of cocaine intoxication which originates from work on heatstroke pathophysiology. This model emphasizes the role of heat, hypohydration (hypernatremia), and increased neuromuscular activity (i.e. accelerated energy consumption, ion flux, and heat production) in activating the sodium pump. A vicious circle is described which leads to increased intracellular sodium concentration, cell swelling, hyperthermia, energy depletion, metabolic cascades, and irreversible cell damage. Named ... |
|
| Atropine, Diazepam, and Physostigmine: Thermoregulatory Effects in the Heat-Stressed Rat |
06 DEC 88 |
9 pages |
| Authors:
Candace B. Matthew; Roger W. Hubbard; Ralph P. Francesconi; ARMY RESEARCH INST OF ENVIRONMENTAL MEDICINE NATICK MA
|
| We have reported that administration of atropine (A) to unrestrained, sedentary, heat-stressed rats resulted in a dose-dependent increase in heating rate (rate of rise of core temperature, C/min). Additionally, we have demonstrated that the decrements in treadmill endurance and increments in heating rate of physostigmine (PH)-treated running rats can both be restored to control levels of pretreating the animals with A and diazepam (D). Our objective in the present work ... |
|
| The Mass-to-Surface Area Index of Heat Tolerance in a Large Cohort |
19 OCT 88 |
|
| Authors:
Lawrence E. Armstrong; Jane P. De Luca; Elaine L. Christensen; Roger W. Hubbard; ARMY RESEARCH INST OF ENVIRONMENTAL MEDICINE NATICK MA
|
| No large mass-to-surface area (M/SA) data base exists which can be used as a reference standard to interpret previous or future M/SA studies. This report presents the M/SA data of a large military cohort (1170 males aged 17-54 yr, 305 females aged 17-40 yr). The effects of gender, race and age on the distribution of M/SA, as well as the relationship between M/SA and other physical characteristics, were described. It ... |
|
| Bibliography of Scientific Publications 1981-1987 |
JUL 1988 |
24 pages |
| Authors:
Kathleen S. Mayer; NAVAL AEROSPACE MEDICAL RESEARCH LAB PENSACOLA FL
|
| This report lists citations of all unclassified research reports, special reports, monographs, journal articles, and proceedings that were published by the Naval Aerospace Medial Research Laboratory during calendar years 1981 through 1987. Keywords: Bibliographics, Medical research, Naval research laboratories, Motion sickness, Scopolamine, Ephedrine, Electrocardiograph, Electrocardiogram, Exercise, Aviator, Speech, Phonological, Microwave, Nystagmic, Flight, Vestibular, Fibroplasia, Rhesus, Macaca mulatta, Acoustic, Primate, Monkey, Noise, Lung, Voice, Model, Operational environment, Vestibular, Vestibulo ocular, Gravitoinertial ... |
|
| Evaluation of Thermal Stress Induced by Helicopter Aircrew Chemical, Biological, Radiological (CBR) Protective Ensemble |
15 JUN 88 |
31 pages |
| Authors:
Jonathan W. Kaufman; Katherine Y. Dejneka; Stephen Morrissey; Alvah Bittner Jr; NAVAL AIR DEVELOPMENT CENTER WARMINSTER PA AIR VEHICLE AND CREW SYSTEMS TECHN OLOGY DEPT
|
| The A/P22P-9(V) Chemical, Biological, Radiological (CBR) Protective Assembly for helicopter aircrews has been evaluated for the additional thermal stress it imparts to users in a hot environment. The standard aircrew life support system for helicopters, based on the CWU-27/P flight coverall, was employed as the experimental control. Two environmental conditions were studied: 1) a simulated hot aircraft interior (hot), with chamber temperatures maintained at dry bulb temperatures = 32.8C and ... |
|
| Heat-Related Illnesses |
APR 88 |
86 pages |
| Authors:
Barry E. Yarbrough; Roger W. Hubbard; ARMY RESEARCH INST OF ENVIRONMENTAL MEDICINE NATICK MA
|
| This chapter in the 2nd edition of the Management of Wilderness and Environmental Emergencies provides background material in the following areas: Physics of heat transfer, physiology of human body temperature regulation, the CNS interface between thermosensors and thermoregulatory effectors, skin blood flow and vasodilation, and acclimatization. The heat illnesses coverage includes information on predisposing factors, thermometry, and fever versus hyperthermia. The review of heat illnesses includes heat cramps, heat edema, ... |
|
| The Impact of Hyperthermia and Hypohydration on Circulation, Strength, Endurance, and Health |
05 FEB 88 |
|
| Authors:
Lawrence E. Armstrong; ARMY RESEARCH INST OF ENVIRONMENTAL MEDICINE NATICK MA
|
| This article reviews the effects of hot environments--and thus hyperthermia and hypohydration--on circulation, strength, endurance, and health in athletes. The cardiovascular responses to heat exposure at rest, and during exercise, are reviewed. Performance is reviewed by examining strength, power and endurance; the impact of hyperthermia, hypohydration and diuretic use on performance are discussed. The physiological needs for water, salt and carbohydrates have been examined. The four major heat illnesses (i.e. ... |
|
| Improvements in Techniques of Microwave Thermography |
FEB 88 |
|
| Authors:
Alan H. Barrett; MASSACHUSETTS INST OF TECH CAMBRIDGE RESEARCH LAB OF ELECTRONICS
|
| This period of research concentrated in the following areas: (1) The development and testing of a reflection-compensating radiometer. (2) A theoretical investigation of the variation of microwave penetration depth in human tissue as a function of the aperture size of the contract antenna. (3) Antenna design to give improved penetration depth. (4) A study of the utility of bistatic measurements to detect embedded tumors and aid microwave thermography and hyperthermia. ... |
|
| Hyperthermia. New Thoughts on an Old Problem |
DEC 87 |
|
| Authors:
Roger W. Hubbard; Lawrence E. Armstrong; ARMY RESEARCH INST OF ENVIRONMENTAL MEDICINE NATICK MA
|
| In this article, the common heat illnesses (heat syncope, salt-and water depletion-heat exhaustion and exertion-induced heatstroke) are briefly reviewed from the perspective of their underlying physiological disturbances, which provide a rational basis for therapy. Due to an apparent paradox between the current clinical dogma and laboratory data, however, the evaluation of the consequences of hyperthermia is extended beyond the usual systematic approach. This raises two new questions: what translates heat ... |
|
| IEEE Engineering in Medicine and Biology Conference (9th) Held in Boston, Massachusetts on 13-16 November 1987 |
NOV 87 |
|
| Authors:
INSTITUTE OF ELECTRICAL AND ELECTRONICS ENGINEERS INC PISCATAWAY NJ
|
| Partial Contents: Aerospace Bioengineering; Anesthesiology; Artificial Organs; Bioelectromagnetics; Bioengineering Challenges In Dentistry; Bioimpedance; Biological Signal Analysis; Biomagnetism; Biomaterials; Biomechanics; Biomedical Education; Biophysics; Biosensors; Biosignal Processing; Biotelemetry/Ambulatory Monitoring; Cardiac Models; Cardiology; Cardiopulmonary Systems; Clinical Engineering; Cochlear Implants and Audiology; Computers in Medicine; EEG Analysis; Engineering to Aid the Physically Handicapped; Ethical and Policy Issues in Health Care; Evoked Potentials; Extracorporeal Circulation; Functional Electrical Stimulation; Health Care Technology; Hyperthermia; Medical Imaging; Modeling ... |
|
| Carbamates, Atropine, and Diazepam: Effects on Performance in the Running Rat |
21 OCT 87 |
|
| Authors:
Candace B. Matthew; Roger W. Hubbard; Ralph P. Francesconi; Glenn J. Thomas; ARMY RESEARCH INST OF ENVIRONMENTAL MEDICINE NATICK MA
|
| We have reported that when rats (500 g, male) are exercised to exhaustion on a treadmill, pretreatment with the centrally acting carbamate physostigmine reduced endurance (run time, RT) an increased the rate of rise of core temperature (Tc+). Both RT and Tc+ were restored to control levels by pretreatment with either or a combination of atropine (A), and diazepam (D). Our objective in the present work was to determine whether ... |
|
| Improvements in Techniques of Microwave Thermography |
OCT 87 |
|
| Authors:
Alan H. Barrett; MASSACHUSETTS INST OF TECH CAMBRIDGE RESEARCH LAB OF ELECTRONICS
|
| During the period 15 November 1984 to 30 June 1985 our efforts continued to make bistatic observations whereby the scattered radiation from an embedded object is studied as a function of the size of the scattering object relative to the wavelength of the radiation to assess the proper wavelength for hyperthermia treatment of malignant tumors. Passive microwave thermography for breast cancer detection uses a radiometer to measure the thermal patterns ... |
|
| Radiofrequency Radiation and Cellular Secretory Processes |
AUG 87 |
|
| Authors:
Ernest N. Albert; Frank Slaby; GEORGE WASHINGTON UNIV MEDICAL CENTER WASHINGTON DC DEPT OF ANATOMY
|
| The purpose of this study was to investigate the effect of unmodulated 915-MHz radiation on the secretory processes of exocrine and endocrine cells under in vitro conditions. Pancreatic tissue slices were exposed to 915-MHz radiation in a Crawford cell exposure system. Sham-exposed slices were either incubated at 37 C or 40 C. These slices were pulse-labeled with tritiated L-leucine and the labeled secretory proteins were determined by autoradiography and counting ... |
|
| Naval Aerospace Medical Research Laboratory Bibliography, 1981-1986 |
JUN 1987 |
23 pages |
| Authors:
Kathleen S. Mayer; NAVAL AEROSPACE MEDICAL RESEARCH LAB PENSACOLA FL
|
| This report lists citations of all unclassified research reports, special reports, monographs, journal articles, and proceedings that were published by the Naval Aerospace Medical Reserch Laboratory during calendar years 1981 through 1986. Keywords: motion sickness; scopolomine; ephedrine; electrocardiograph; electrocardiogram; exercise; speech; microwave; flight; fibroplasia; acoustic; monkey; noise; hearing; circadian rhythm; nonionizing radiation; brain; hypothermia; hyperthermia; cardiopulmonary; bibliographics. |
|
| Proceedings of the Annual Northeast Bioengineering Conference (13th) Held in Philadelphia, Pennsylvania on 12-13 March 1987. Volume 2 |
13 MAR 87 |
|
| Authors:
Kenneth R. Foster; INSTITUTE OF ELECTRICAL AND ELECTRONICS ENGINEERS INC NEW YORK
|
| Partial contents of Volume 2 Cardiology; Mechanics of the Left Ventricle: Effects of Radial Activation and Twisting Motion; Weightlessness as a Cardiac Emergency Assist Device; Electrical Activity of the Gut: Fundamental Information for Evaluation of GI Modal Function; True Volume Flow Measurement with Multibeam Ultrasound Doppler; Doppler Blood Flow Studies of Breast Tissue at Normal and Reduced Ambient Pressures; A Fluid Mechanical Analysis of Esophagael Transport; Determination of Blood Flow ... |
|
| Evaluation of Drugs for Prevention of Hyperthermia in Rats Exposed to Microwave Irradiation |
04 MAR 1987 |
17 pages |
| Authors:
James Knepton; Brenda Cobb; NAVAL AEROSPACE MEDICAL RESEARCH LAB PENSACOLA FL
|
| The objective of this study was to determine the effectiveness of two antipyretic drugs, indomethacin and dihydrotachysterol, in the prevention of microwave-induced hyperthermia in rats. Indomethacin has been proven effective in reducing fever of pyrogenic origin. Dihydrotachysterol (DHT) is effective in increasing survival of rats during heat stress. After being acclimated to restraint in an acrylic cone-shaped holder and to the presence of a colonic temperature probe each rat was ... |
|
| Rapid Hypothermia Subsequent to Oral Nicotinic Acid and Immersion in Warm (30C) Water |
MAR 87 |
6 pages |
| Authors:
Roger W. Hubbard; Lawrence E. Armstrong; Andrew J. Young; ARMY RESEARCH INST OF ENVIRONMENTAL MEDICINE NATICK MA
|
| The purpose to this letter to the Editor is to describe the results of pilot studies conducted to evaluate body cooling by water immersion, with and without nicotinic acid. Nicotinic acid pretreatments resulted in greater body cooling than control trials. However, cooling rates were less than can be achieved with evaporative cooling techniques. The striking feature of the nicotinic acid trials involved the magnitude of body cooling achieved in relatively ... |
|
| Further Evidence That Stress Hyperthermic is a Fever |
87 |
|
| Authors:
Matthew J. Kluger; Barbara O'Reilly; Timothy R. Shope; Arthur J. Vander; MICHIGAN UNIV ANN ARBOR DEPT OF PHYSIOLOGY
|
| Exposure of rats to an open-field results in a rapid rise in body temperature. Fifty-four percent of this rise in body temperature was blocked by intracerebroventricular administration of the antipyretic drug sodium salicylate. Intraperitoneal administration of indomethacin, a potent blocker of prostaglandin production, also attentuated the stress-induced hyperthermia to the same degree. Based on the data presented in this an earlier study, we conclude that a major component of the ... |
|
| The Effects of Cortisol, Corticosterone, Insulin and Glucose Pre- and Post-Treatment on Heatstroke in Rats and the Kinetics of Uptake and Cellular Response |
27 DEC 86 |
|
| Authors:
Margaret E. Tolbert; Abraham Weaver; Vernetta E. Hicks; Cynthia Belton; TUSKEGEE UNIV AL CARVER RESEARCH FOUNDATION
|
| In studies of heat stress, a series of in vivo and in vitro experiments were designed to determine if mixtures of either cortisol or corticosterone plus insulin and glucose have beneficial effects on hyperthermic rats. Hyperthermia was induced in male rats (450 to 550 grams) by exposure to severe heat loads (42 C to 42.6 C). The rats were then allowed to cool to or below 40.4 C. Blood samples ... |
|
| Afferent Mechanisms of Microwave-Induced Biological Effects |
JUL 86 |
|
| Authors:
Henry Lai; UNIV OF WASHINGTON SEATTLE
|
| We studied the effects of 2450MHz circularly polarized microwave irradiation on central nervous system functions. Pulsed (microsecond, 500 pps) microwaves decreased high affinity sodium-dependent choline uptake in the hippocampus and frontal cortex of the rat. The effect on hippocampal choline uptake was blocked by pretreatment with narcotic antagonists. Continuous-wave microwaves of the same power density decreased choline uptake in the frontal cortex only. Furthermore, we found that the effects of ... |
|
| The Yale Journal of Biology and Medicine. Volume 59, Number 3, May-June 1986. An International Symposium sto Debate Current Issues in Thermal Physiology. Part 1 |
JUN 86 |
|
| Authors:
JOHN B PIERCE FOUNDATION LAB NEW HAVEN CONN
|
| Partial contents: Is a Decrease in Cardiac Filling Pressure the Limiting Factor in Adjusting to Heat Stress; Are Non-Thermal Factors Important in the Cutaneous Vascular Response to Exercise; Do Black-Box Models of Thermoregulation Still Have Research Value. |
|
| Inhalation Toxicology. VIII: Establishing Heat Tolerance Limits for Rats and Mice Subjected to Acute Exposures at Elevated Air Temperatures |
MAY 86 |
|
| Authors:
Charles R. Crane; Donald C. Sanders; FEDERAL AVIATION ADMINISTRATION WASHINGTON DC OFFICE OF AVIATION MEDICINE
|
| Experimental animal subjects are used most commonly to assess the toxicity of thermal decomposition products (smoke) from burning materials. Nascent smoke is obviously quite hot; therefore, the design of smoke toxicity assay systems must provide for adequate cooling of the gases prior to exposure of the animals. This research has addressed the question of how much cooling is required. Rats and mice were exposed to elevated air temperatures over the ... |
|
| Heat Exchange Responses to Anticholinergics |
MAR 86 |
|
| Authors:
Richard R. Gonzalez; Margaret A. Kolka; ARMY RESEARCH INST OF ENVIRONMENTAL MEDICINE NATICK MA
|
| Among the drugs used for treatment of psychoses are those compounds which impart a degree of anticholinergic activity on eccrine sweat glands. This disrupts thermoregulation but the mechanism is not known. Atropine (used by the U.S. Army as a nerve agent antidote) reduces thermoregulatory sweating, causing intense heat storage leading to hyperpyrexia. Saline and atropine (2 mg im) were injected in 14 healthy male subjects before and after heat acclimation ... |
|
| Hyperthermia Induced by Open-Field Stress is Blocked by Salicylate |
86 |
|
| Authors:
Rebecca Singer; Christian T. Harker; Arthur J. Vander; Matthew J. Kluger; MICHIGAN UNIV ANN ARBOR DEPT OF PHYSIOLOGY
|
| Psychological stress results in a rise in body temperature. Here we report that in rats, hyperthermia induced by open-field stress can be blocked by administration of the antipyretic drug sodium salicylate. These data suggest that this rise in body temperature is a true fever, perhaps mediated by prostaglandins. Keywords: Interleukin-1; Temperature regulation. (Reprints). ANNOTATION: Reprint: Hyperthermia Induced by Open-Field Stress is Blocked by Salicylate. |
|
| Physiological Responses to WBGT-Equivalent Environments and Two Clothing Types during Simulated Desert Marches |
DEC 85 |
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| Authors:
Lawrence E. Armstrong; Patricia C. Szlyk; Roger W. Hubbard; Dianne B. Engell; Ingrid V. Sils; ARMY RESEARCH INST OF ENVIRONMENTAL MEDICINE NATICK MA
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| The purpose of this investigation was two-ofld: (1) to determine if hot-wet and hot-dry environments were equally stressful to the exercising individual and (2) to examine the effects of clothing (shorts vs modified Battle Dress Uniform) worn while exercising in both environments. The physiological effects of exercise in a hot-humid environment (89 F, 80% RH) have been compared to those of exercise in a hot-dry environment (104 F, 28% RH), ... |
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| Circadian Variation in Host Defense |
18 NOV 85 |
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| Authors:
Matthew J. Kluger; MICHIGAN UNIV ANN ARBOR DEPT OF PHYSIOLOGY
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| We have been monitoring the body temperature and relative activity of up to 24 rats at a time using a recently developed biotelemetry system (The Dataquest III; Mini-Mitter Company). Each cage is maintained in a constant temperature chamber at 27 C and is on a 12:12 hour light-dark cycle. In the process of testing the versatility of this system and obtaining pilot data we have generated data for two manuscripts ... |
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| Proceedings of MELECON '85, Mediterranean Electrotechnical Conference. Held in Madrid, Spain on October 8, 9, 10 1985. Volume 1. Bioengineering |
OCT 85 |
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| Authors:
Antonio Luque; A. R. Figueiras-Vidal; J. M. Delgado; INSTITUTE OF ELECTRICAL AND ELECTRONICS ENGINEERS INC NEW YORK
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| The IEEE Mediterranean Electrotechnical Conference (MELECON '85) is being held October 8, 9 and 10, 1985 at the Palace of Exhibitions and Congresses in Madrid, Spain. The papers included in these Proceedings represent the authors technical contributions presented at MELECON '85. They cover an extended technical program arranged in 45 sessions. New technologies are highlighted with links between theory and applications. This third Mediterranean Electrotechnical Conference covers topics in Bioengineering, ... |
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| Improvements in Techniques of Microwave Thermography |
11 JUN 85 |
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| Authors:
Alan H. Barrett; MASSACHUSETTS INST OF TECH CAMBRIDGE RESEARCH LAB OF ELECTRONICS
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| During the period 15 November 1983 to 15 November 1984 our efforts have focussed on (1) modifying our 3 and 6 GHz radiometers for reflection compensation and making design changes to improve the stability, (2) designing antennas to give improved penetration depth, and (3) bistatic measurements whereby the scattered radiation from an embedded object is determined to provide information on the size of the object and the proper frequency for ... |
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Reports by Keyword(s)
HYPERTHERMIA
