| Hepatitis C. Virus Infection: Mechanisms of Disease Progression |
OCT 2006 |
9 pages |
| Authors:
Maria H. Sjogren; Brooke Huntley; TRUE RESEARCH FOUNDATION SAN ANTONIO TX
|
 | An estimated 4.1 million individuals in the United States are chronically infected with the hepatitis C virus. Annually 8,000 to 10,000 of these subjects will die of liver-related complications and approximately 1,000 will require liver transplantation. The U.S. military has rates of HCV infection similar to the general U.S. population (1.6%). However, it is a younger population and its natural history of HCV infection has not been studied. Therefore, the ... |
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| Learning from Experience: The Public Health Response to West Nile Virus, SARS, Monkeypox, and Hepatitis A Outbreaks in the United States |
01-Jan-2005 |
|
| Authors:
Kristin Leuschner; M S Ridgely; Lois M Davis; David J Dausey; Michael A Stoto; Jeffrey Wasserman; Karen Ricci; Stuart Olmsted; Sarah Myers; Nicole Lurie; Elizabeth M Sloss; RAND HEALTH SANTA MONICA CA
|
 | Over the past three years, the U.S. Department of Health and Human Services (HHS) has made significant investments in state and local public health in an effort to enhance public health emergency preparedness. The RAND Corporation was contracted to work with the HHS Office of the Assistant Secretary for Public Health Emergency Preparedness (OASPHEP) to develop resources and to prepare analyses to help describe and enhance key aspects of state ... |
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| Utilization of Telemedicine for Evaluation and Treatment of Hepatitis C Patients in Military Health Clinics |
OCT 2001 |
|
| Authors:
Kent Holtzmuller; WALTER REED ARMY MEDICAL CENTER WASHINGTON DC
|
|
| Utilization of Telemedicine for Evaluation and Treatment of Hepatitis C Patients in Military Health Clinics |
MAY 2000 |
4 pages |
| Authors:
Kent Holtzmuller; WALTER REED ARMY MEDICAL CENTER WASHINGTON DC
|
| The hepatitis C Telemedicine project is being conducted in three phases. The first phase of the project is to validate the use of desktop VTC system connected at 384 kbs to visually diagnose patients with physical findings secondary to chronic liver disease. Diagnostic agreement between in person, face-to-face evaluations versus those performed using the VTC system will be compared in patients with liver disorders. This first phase of the project ... |
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| Studies into Militarily Relevant Infectious Diseases of Interest to BothUnited States and Royal Thai Governments |
NOV 1999 |
60 pages |
| Authors:
M. G. Puavilai; ARMED FORCES RESEARCH INST OF MEDICAL SCIENCES/ROYAL THAI ARMY MEDICAL COMPONENT BANGKOK
|
| The Armed Forces Research Institute of Medical Sciences (AFRIMS) conducts research into infectious diseases with both military and public health relevance to both the United States and Royal Thai Governments. Studies leading to the prevention of HIV infections are of primary importance to the Royal Thai Army. In addition. malaria, dengue, hepatitis, Japanese encephalitis, scrub typhus, and infectious diarrhea are all areas in which the ... |
|
| Hepatic Toxicity of Perfluorocarboxylic Acids |
JUL 96 |
11 pages |
| Authors:
Nicholas V. Reo; WRIGHT STATE UNIV DAYTON OH
|
| This AASERF grant has provided support for two graduate students in the Biomedical Sciences Ph.D. Program at Wright State University, Dayton, OH. A Ph.D. degree was conferred in 1994 to C. Goecke- Flora, while the other student, M. Adinehzadeh, currently continues in the program. These students were provided a stipend, a nominal budget for research supplies, and travel funds which enabled them to present their data at national scientific conferences. ... |
|
| Medical Surveillance Monthly Report (MSMR). Volume 2, Number 1, January 1996 |
Jan-1996 |
21 pages |
| Authors:
John F Brundage; ARMED FORCES HEALTH SURVEILLANCE CENTER SILVER SPRING MD
|
| Twenty-eight cold weather injuries were reported from 1 October 1995- 31 December 1995 compared to 16 injuries reported during the same period one year ago. Fifty percent (14) of the injuries were frostbite of the fingers. Ten of these were first degree injuries, three were second degree, and one was third degree frostbite. Seventeen percent (5) of the injuries involved frostbitten feet; two were first degree injuries (including one hospitalization), ... |
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| Protective Immunity to Hepatitis B and Streptococcus Pneumoniae in Active Duty Women Versus Men: Prevalence and Response to Preventive Immunization |
30 SEP 1995 |
8 pages |
| Authors:
Renata J. Engler; WALTER REED ARMY MEDICAL CENTER WASHINGTON DC
|
| Women in the military may have an increased occupational of hepatitis B infection. There is currently on clear data available regarding differences in duration of vaccine response between men and women. This study will provide data regarding the prevalence of protective immunity among active duty women in different age groups, under the current guidelines of immunization practice. In addition, a cost-effective vaccine booster strategy will be compared to the standard ... |
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| Assessment and Intervention for the Reduction of Adverse Gynecologic and Obstetric Clinical Events in Naval Personnel Aboard Ship |
25 AUG 95 |
30 pages |
| Authors:
Stephanie K. Brodine; NAVAL HEALTH RESEARCH CENTER SAN DIEGO CA
|
| Unplanned pregnancies (UPs) and sexually transmitted diseases (STDs) continue to be epidemic in active-duty women, resulting in morbidity and high financial costs with an adverse impact on combat readiness. However, the exact rates and the predisposing factors are not clearly defined. This project will document the prevalence and incidence of UPs and STDs in women assigned to two commands and define the demographic and behavioral correlates for both of these ... |
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| Tetrachorobiphenyl Metabolism, Toxicity, and Regulation of Cytochrome P45O Expression in a Marine Teleost Fish |
FEB 95 |
|
| Authors:
Renee D. White; MASSACHUSETTS INST OF TECH CAMBRIDGE
|
| The effects of 3,3',4,4'-Tetrachlorobiphenyl (TCB) were examined in scup (Stenotomus chrysops). A low TCB dose elicited strong induction of hepatic CYPlAl mRNA, protein, and activity. A high TCB dose elicited strong induction of hepatic CYPlAl mRNA, but not of CYPlAl protein or activity. This 'suppression' at the high dose was specific for CYPlAl, and was not seen for other enzymes. In vitro studies indicate that hepatic CYPlAl is inactivated in ... |
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| Hepatic Metabolism of Perfluorinated Carboxylic Acids: A Nuclear Magnetic Resonance Investigation in Vivo |
17 JAN 95 |
19 pages |
| Authors:
Nicholas V. Reo; WRIGHT STATE UNIV DAYTON OH
|
| This report outlines our progress regarding toxicological studies of perfluoro- n-octanoic acid (PFOA) and perfluoro-n-decanoic acid (PFDA). These Air Force chemicals belong to a class of compounds known as peroxisome proliferators (PP). Many PP cause hepatotoxicity and carcinogenesis in rodents. The mechanisms are unknown and represent an active area of research. Recent studies have demonstrated specific effects of PFDA treatment on hepatic phospholipid and carbohydrate metabolism. PFDA alters hepatic glucose ... |
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| New Approaches to Hepatitis A Vaccine Development |
26 OCT 94 |
33 pages |
| Authors:
Stanley M. Lemon; NORTH CAROLINA UNIV AT CHAPEL HILL
|
| Research has been directed at the development of a safe, inexpensive and effective hepatitis A vaccine. Neutralization epitopes on the surface of the HAV capsid have been characterized in detail. A single linear antigenic site on the virus capsid which found to be reactive with a murine neutralizing monoclonal antibody. Poliovirus antigenic chimeras were engineered which expressed amino acid sequences of this HAV epitope within its VP 1 capsid protein, ... |
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| Threat of Hepatitis E Virus Infection in Somalia During Operation Restore Hope |
05 AUG 1994 |
4 pages |
| Authors:
James P. Burans; Trueman Sharp; Mark Wallace; Charles Longer; Scott Thornton; NAVAL MEDICAL RESEARCH UNIT NO 3 CAIRO (EGYPT) DEPT OF MEDICAL ZOOLOGY
|
| In support of Operation Restore Hope, the United States military established a diagnostic laboratory for infectious diseases, the Joint Forward Laboratory, in Mogadishu, Somalia. Because sporadic hepatitis due to unknown causes was a frequent problem, staff members of the Joint For-ward Laboratory evaluated 31 Somalis, five displaced Ethiopians, and three Western relief workers who had acute clinical hepatitis. Patients lived in multiple locations in Somalia-Mogadishu, Baidoa, and Merca - and ... |
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| Viral Hepatitis in the U.S. Air Force, 1980-89: An Epidemiological and Serological Study |
MAY 1994 |
6 pages |
| Authors:
Ronald W. Stout; Susan B. Mitchell; Michael D. Parkinson; Ronald D. Warner; Ralph E. Miles; ARMSTRONG LAB BROOKS AFB TX
|
| This paper reports the epidemiology of hospital-diagnosed acute viral hepatitis in US Air Force personnel from 1980-1989. First hospitalizations for viral hepatitis generally declined, ranging from 24.6 to 47.2 per 100,000 personnel. Hepatitis rates were higher among men, (RR = 1.3; 95% C.I., 1.1 - 1. 5) and higher among blacks, compared to whites (RR = 1.4; 95% C.I., 1.3 - 1.6). Analysis of risk associated with various occupations demonstrated ... |
|
| Chronic Liver Disease in Peru: Role of Viral Hepatitis |
1994 |
5 pages |
| Authors:
W. B. Barham; R. Figueora; I. A. Phillips; K. C. Hyams; NAVAL MEDICAL RESEARCH INST BETHESDA MD
|
| The prevalence of antibodies to hepatitis C virus (anti-HCV) was determined in 105 patients with biopsy-proven chronic liver disease and 128 comparison patients without any evidence of liver pathology living in Lima, Peru. Using a second-generation EIA screening and supplemental immunoblot assay, anti-HCV was detected in four of 13 patients with chronic hepatitis, in 11% of 85 patients with cirrhosis, and none of seven patients with hepatocellular carcinoma. Only two ... |
|
| Hemoglobin-Based Oxygen-Carrying Resuscitation Fluids |
1994 |
8 pages |
| Authors:
Rabinovici Reuven; Rudolph S. Alan; Neville F. Lewis; Feuerstein Giora; JEFFERSON MEDICAL COLL PHILADELPHIA PA
|
| Currently, transfusion of donor blood is the conventional treatment for profound hemorrhagic shock (?ATLS). However, very significant problems are inherent in human blood transfusions. First, there is an increasing shortage of donors which becomes more severe due to the rising incidence of AIDS carriers in blood- donating populations (5). Second, red blood cells carry multiple antigenic determinants so that donor blood must be carefully typed and ... |
|
| Low Risk of Sexual Transmission of Hepatitis C Virus in Somalia |
1994 |
3 pages |
| Authors:
Douglas M. Watts; Andrew L. Corwin; Kenneth C. Hyams; Mahmoud A. Omar; NAVAL MEDICAL RESEARCH INST BETHESDA MD
|
| The prevalence in Somalia of antibody to hepatitis C virus (anti-HCV) was determined in a survey of 236 female prostitutes, 80 sexually transmitted disease (STD) clinic patients, 79 male soldiers, and 43 tuberculosis patients. Of 98 (22%) serum samples repeatedly anti-HCV reactive by first and second generation enzyme-linked immunosorbent assay kits, only 8 (1.8%) were anti-HCV positive by immunoblot assay (RIBA-2). Anti-HCV seropositivity by immunoblot assay was not associated with ... |
|
| The Success of Hepatitis A Vaccine |
APR 1993 |
3 pages |
| Authors:
ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK MD
|
| The report by Lee et al., published in this issue of GASTROENTEROLOGY, gives us necessary information to assess the safety and immunogenicity of the of the SmithKline Beecham hepatitis A vaccine in children. Although the efficacy trials cited above were performed in children, logistical problems did not allow the vigorous clinical and serological monitoring that smaller safety trials permit. The work by lee et al not only fills this information ... |
|
| New Approaches to Hepatitis A Vaccine Development |
30 MAR 93 |
38 pages |
| Authors:
Stanley M. Lemon; NORTH CAROLINA UNIV AT CHAPEL HILL
|
| Hepatitis A virus (HAV) has historically been an important cause of morbidity among U.S. soldiers in the field. Work under this contract is directed at the development of a safe, inexpensive and effective hepatitis A vaccine for use in military personnel. Two main research approaches are under investigation. First, we are characterizing neutralization escape mutants of HAV and examining synthetic oligopeptides representing the suspected surface structures of HAV. Octapeptides have ... |
|
| Evaluation of Hepatitis B Virus Photoinactivation in Serum and Cellular Blood Components by the Polymerase Chain Reaction |
AUG 92 |
66 pages |
| Authors:
Fabrizio Saraceni; AIR FORCE INST OF TECH WRIGHT-PATTERSON AFB OH
|
| The purpose of this study was to investigate the usefulness of the polymerase chain reaction as a tool in the photoinactivation of transfusion transmitted viruses. There are currently two major methods of inactivating viruses in blood components. One is an oxygen dependent, membrane directed method and the other is a nucleic acid directed method. Current methods of evaluating photoinactivation involve either viral cultures or chimpanzee infectivity studies. These evaluation methods ... |
|
| Clinical Types of Hepatitis B, |
APR 1992 |
|
| Authors:
Mario Rizzetto; Robert Nisini; TURIN UNIV (ITALY)
|
| Hepatitis B is a parenterally and sexually transmitted disease of global importance. The disease runs more frequently a subclinical and anicteric course, with a significative rate of cases that become chronic. Chronic hepatitis may progress to cirrhosis or cancer. The strategies by which Hepatitis B can be diminished and eventually eliminated are: immunization, measures to prevent exposure to infective blood or blood derivatives and education (in particular awareness that hepatitis ... |
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| Vaccination Against Hepatitis B: The Italian Strategy, |
APR 1992 |
|
| Authors:
A.R. Zanetti; J. Grappasonni; E. Tanzi; L. Romano; CAMERINO UNIV (ITALY)
|
| Viral hepatitis type B is major worldwide public health problem. Infection with the hepatitis B virus (HBV) may progress to chronic liver disease including chronic active hepatitis, cirrhosis and hepatocellular carcinoma. Moreover it has been estimated that between 200 and 300 million individuals in the world are chronic carriers of HBV. The availability of safe and effective vaccines allows the establishment of immunization programs aimed at the elimination of hepatitis ... |
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| Future Approaches to Vaccine Development Single-Dose Vaccines Using Controlled-Release Delivery Systems, |
APR 1992 |
|
| Authors:
Dr. M. T. Aguado; WORLD HEALTH ORGANIZATION GENEVA (SWITZERLAND)
|
| The development of new vaccines, both more efficacious and easier to deliver, has become an area of research that can certainly benefit from recent technical developments. In particular, the conversion of multiple-dose vaccines into single-dose vaccines may represent an important advance which should lead to improved vaccination coverage, as well as to a reduction in vaccination costs. In order to be fully immunized against diphtheria, pertussis, tetanus, poliomyeltis and hepatitis ... |
|
| Inactivation of Hepatitis A Virus (HAV) by Chlorine and Iodine in Water |
JUN 90 |
152 pages |
| Authors:
Mark D. Sobsey; NORTH CAROLINA UNIV AT CHAPEL HILL
|
| The inactivation kinetics of hepatitis A virus (HAV), poliovirus 1 (Pl) and echovirus 1 (El) by free chlorine and Army iodine (globaline) were studied in phosphate buffered, halogen demand free-water (PBDFW) and in PBDFW supplemented with 5 NTU of clay tubdidity and 10 mg/l humic+fulvic acids. HAV was rapidly inactivated by free chlorine under all conditions tested (1-7 mg/L, 5 and 25 C, pH 4.5, 7.0 and 9.5), with 99.99% ... |
|
| New Approaches to Hepatitis A Vaccine Development |
MAR 90 |
|
| Authors:
Stanley M. Lemon; NORTH CAROLINA UNIV AT CHAPEL HILL
|
| Hepatitis A virus (HAV) has historically been an important cause of morbidity among U.S. soldiers in the field. Work under this contract is directed at the development of a safe, inexpensive and effective hepatitis a Vaccine for use in military personnel. Two main research approaches are under investigation. First, we are examining synthetic oligopeptides representing the suspected surface structures of HAV. Octapeptides have been synthesized on polyethelene pins and probed ... |
|
| Development of a Controlled Release Delivery System for Immunogens |
15 FEB 90 |
28 pages |
| Authors:
Judith P. Kitchell; DYNAGEN INC CAMBRIDGE MA
|
| The development program addresses the problem of effectively protecting military personnel from bacterial, viral, or toxic incapacitation. At the present, logistical problems in carrying out a protective program remain formidable because vaccination programs involve: multiple injections; administration by trained medical personnel; and careful medical record maintenance. An approach to reducing the 'Logistical problems is to modify immunization formulations so that single doses confer complete immunity. The overall program goal is ... |
|
| New Approaches to Attenuated Hepatitis A Vaccine Development: Cloning and Sequencing of Cell-Culture Adapted Viral cDNA |
01 OCT 89 |
|
| Authors:
Stanley M. Lemon; NORTH CAROLINA UNIV AT CHAPEL HILL
|
| An infectious cDNA clone derived from virulent HAV would be of considerable value in experiments designed to determine the molecular base of attenuation, and would provide the basis for new approaches to developing candidate attenuated viruses. In an effort to assemble such a clone, partial inserts from ten HM175 cDNA clones were assembled into a single construct containing the consensus p16 HM175 sequence. Flanking homopolymeric dC-dG tails derived from the ... |
|
| Safety Testing of Dengue-1 and Dengue-3 Seeds for Human Challenges, Unattenuated; Hepatitis A Virus, Strain HM-175 |
21 MAR 89 |
|
| Authors:
Louis Potash; FLOW LABS INC MCLEAN VA
|
| Hepatitis A Virus Vaccine, Strain HM-175, FI-2, Lot No. 1 of Jan 89 was satisfactorily safety tested in accordance with the guidelines established by the FDA for live and inactivated vaccines. Keywords: Dengue-1; Dengue-3; Hepatitis A; Viral seeds; Vaccine; RA-1. (kt) |
|
| Epidemiology of Hepatitis B in the Gezira Region of Sudan |
Jan-1989 |
10 pages |
| Authors:
Kenneth C Hyams; Mohamed A Al-Arabi; Ahmed A Al-Tagani; James F Messiter; Abdella A Al-Gaali; John F George; NAVAL MEDICAL RESEARCH UNIT NO 3 FPO NEW YORK 09527
|
| To determine the prevalence of and risk factors for hepatitis B infection in rural Sudan, 2 villages in the Gezira were surveyed. There were 851 subjects (age 1-89 years; mean age 24.6 years) of equal sex distribution, 408 from Khalawaat and 443 from Saleim. HBsAg was found in 18.7% and seropositivity for any hepatitis marker (HBsAg, anti-HBs, or anti-HBc) was found in 63.9%. The prevalence of HBsAg was highest in ... |
|
| Safety Testing of Dengue-1 and Dengue-3 Seeds for Human Challenges, Unattenuated; Hepatitis A Virus, Strain HM175 |
01 JUL 88 |
|
| Authors:
Louis Potash; FLOW LABS INC MCLEAN VA
|
| Hepatitis A Virus, Strain HM175, Vaccine F I-2, Lot 1A of 16 Oct 87 and Lot 1B of 4 Dec 87 was satisfactorily safety-tested in accordance with the guidelines established by the FDA for live and inactivated vaccines as stipulated in 21 CFR, Parts 610.11, 610.12, 630.10-630.17, etc. All testing procedures were carried out following Good Laboratory Practices (GLP) regulations (21 CFR, Part 58). Results are reported herein. Keywords: Vaccines; ... |
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| Studies on the Pathogenesis of Hepatitis A and Feasibility Studies on a Hepatitis A Vaccine |
14 JUN 88 |
|
| Authors:
Elvera Ehrenfeld; Oliver R. Richards; Donald F. Summers; UTAH UNIV SALT LAKE CITY SCHOOL OF MEDICINE
|
| The objectives of this work are to produce hepatitis A virus (HAV) antigens by recombinant DNA technology to identify antigens that may induce a protective immune response, and to construct vectors that can be used to stimulate enteric mucosal immunity against HAV. Viral cDNA sequences encoding capsid proteins or selected parts of capsid proteins VP1 and VP3 have been cloned into several bacterial expression vectors, and have been shown to ... |
|
| Epidemiological Survey for Incidence of Shigellosis and Hepatitis to Evaluate Potential Field Test Sites for Vaccine Trials. Part 2. Viral Hepatitis |
MAR 88 |
|
| Authors:
Manfred S. Green; Dani Cohen; Colin Block; Tsvi Rouach; ISRAEL DEFENCE FORCES TEL-AVIV MILITARY POST 02149
|
| Hepatitis A virus (HAV) infection is highly endemic in Israel and extensive use of immune serum globulin is used to prevent the disease in the military. With the recent advances in the development of the new HAV vaccines, it has become necessary to evaluate the possibility of a vaccine trial in the IDF. In order to identify candidate populations for the trial, two groups were evaluated in this study. The ... |
|
| New Approaches to Attenuated Hepatitis a Vaccine Development: Cloning and Sequencing of Cell-Culture Adapted Viral cDNA |
13 OCT 87 |
|
| Authors:
Stanley M. Lemon; NORTH CAROLINA UNIV AT CHAPEL HILL
|
| Hepatitis A virus (HAV) is a human picornavirus with a worldwide distribution. It poses a considerable threat to military forces of the United States due to its capacity for epidemic spread, and the fact that acute hepatitis A associated with primary infection with HAV is a protracted illness with a prolonged convalescence. No vaccine is currently available for prevention of infection with this medically important virus. Three general approaches to ... |
|
| Worldwide Report, Epidemiology |
16 JAN 1987 |
|
| Authors:
JOINT PUBLICATIONS RESEARCH SERVICE ARLINGTON VA
|
| This Worldwide report contains articles on Epidemiology. |
|
| New Approaches to Attenuated Hepatitis A Vaccine Development: Cloning and Sequencing of Cell-Culture Adapted Viral cDNA |
13 OCT 86 |
|
| Authors:
Stanley M. Lemon; NORTH CAROLINA UNIV AT CHAPEL HILL
|
| The goal of this research contract is to develop an improved understanding of the biological basis of cell culture adaptation and attenuation of Hepatitis A Vaccine (HAV), as this may ultimately lead to a rational approach to development of an effective attenuated vaccine. Accordingly, a cDNA genomic library spanning over 98% of the genome of a plaque-purified, cell culture- adapted variant of HM175 strain HAV (p17 ca-HM175) has been prepared ... |
|
| Control of Hepatitus Virus Infections by New Methods |
DEC 85 |
|
| Authors:
Joseph L. Melnick; BAYLOR COLL OF MEDICINE HOUSTON TX
|
| Studies were performed in a young adult population with an HBsAg/adw polypeptide vaccine prepared from native intact HBsAg particles. It was demonstrated that on a weight basis the polypeptide vaccine was superior to Heptavax-B in generating an antiHBs response, indicating that the critical antigenic determinants for inducing an antiHBs response are associated with the low-molecular-weight polypeptides of HBsAg. In addition to the excellent peak antibody response generated by the polypeptide ... |
|
| Induced Oral Infection of the Owl Monkey (Aotus trivirgatus) with Hepatitis A Virus |
MAY 85 |
|
| Authors:
C. J. Trahan; J. W. LeDuc; E. C. Staley; R. H. Marchwicki; S. M. Lemon; ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK MD
|
| Several species of nonhuman primates have served as animal models for hepatitis A virus (HAV) infection and disease. This study was to determine the suitability of Aotus trivirgatus as an orally induced model for HAV infection, and to reconfirm the owl monkey's susceptibility to the intravenous route of inoculation. Animals were inoculated, either orally or intravenously, with varying concentrations of PA-33 strain of HAV. ALT, AST, and GGTP levels were ... |
|
| A Study of Hepatitis B in the Canadian Forces |
85 |
|
| Authors:
J. A. Embil; DALHOUSIE UNIV HALIFAX (NOVA SCOTIA)
|
| The study of the presence of antibodies to Hepatitis B core antigen in recruits undergoing basic training at CFB Cornwallis between 1981 and 1983 has raised more questions than it has answered. While it is gratifying to how that our young adults are within normal range for their age group in the areas north of the Mexican border, the question arises as to why the female subjects seem to have ... |
|
| Infectious Hepatitis in Canadian Forces Personnel |
85 |
|
| Authors:
J. A. Embil; DALHOUSIE UNIV HALIFAX (NOVA SCOTIA)
|
| This study was established to study the prevalence of infectious Hepatitis (Hepatitis A) antibody (anti-HAV) in several groups of CF personnel in order to assist the Surgeon General in assessing the hazard of the disease and to indicate the effectiveness of conventional immune globulin administration for prevention of infection among personnel posted in areas of high risk. In additio;n, itd is expected that a vaccine for Hepatitis A will become ... |
|
| Amoebic Liver Abscess Presenting as Fever of Unknown Origin (FUO). Serology, Isotope Scanning and Metronidazole Therapy in Diagnosis and Treatment |
82 |
|
| Authors:
Z. Farid; B. Trabolsi; M. E. Kilpatrick; W. M. Yassin; R. H. Watten; ABBASSIA FEVER HOSPITAL CAIRO (EGYPT)
|
| In a study of obscure fevers in Cairo, Egypt, 24 cases of hepatic amoebiasis were diagnosed during a 3-year period from 1977-1980. The counterimmunoelectrophoresis amoebic serologic test was positive in 20 of the 24 patients and was very useful in confirming the diagnosis. The four patients in whom the test was negative had been ill for between 1 and 5 months and had been treated with antibiotics and amoebicidal drugs. ... |
|
| Mass Spectrometric Rapid Diagnosis of Infectious Diseases |
JAN 1979 |
|
| Authors:
Michael Anbar; James McReynolds; Michael Scanlon; William Rieth; STATE UNIV OF NEW YORK AT BUFFALO SCHOOL OF MEDICINE
|
| Using new chemical procedures, mass spectrometric instrumentation and appropriate computerized data analysis, the diagnostics of infectious hepatitis, through the molecular weight profile of neutral metabolites urine, was demonstrated. (Author) |
|
| Intrinsic Interference Assay for Hepatitis Virus. |
MAY 1975 |
|
| Authors:
David H. Carver; JOHNS HOPKINS UNIV BALTIMORE MD SCHOOL OF MEDICINE
|
| Overall objectives to total project were: The further development of the intrinsic interference system as an assay for the growth of the hepatitis viruses (A and B) in tissue culture; The use of the above system to study the pathogenesis of hepatitis indicated by the sequential sites from which the virus can be isolated and by the kinetics of development of neutralizing antibody against these viruses; and The attenuation of ... |
|
| Studies of Viral Hepatitis. |
31 DEC 1974 |
|
| Authors:
A. W. Holmes; F. Deinhardt; PRESBYTERIAN-ST LUKE'S HOSPITAL CHICAGO ILL
|
|
| Morphological Studies of Hepatitis. |
1973 |
|
| Authors:
Fenton Schaffner; MOUNT SINAI SCHOOL OF MEDICINE NEW YORK
|
| The effort in the last year has been mainly devoted to the study of hepatitis B antigen (HB Ag) in liver tissue. This was done in liver biopsy specimens obtained for histologic diagnosis from HB Ag positive patients with acute or chronic hepatitis. The tissue was studied by electron microscopy with and without incubation with antibody to HB Ag labeled with ferritin or with horse radish peroxidase. In chronic carriers ... |
|
| Immune Response to a Secondary Stimulus with Leptospira Canicola and Infectious Canine Hepatitis in Beagles Exposed to SR90 |
JUN 1966 |
17 pages |
| Authors:
W. E. Clapper; A. Sanchez; J. Levy; LOVELACE FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH ALBUQUERQUE NM
|
| The secondary immune response to L. canicola and ICH virus was depressed in Beagle dogs which had inhaled particles of Sr90 1-2 days and 7 days before the immune stimulus. The initial body burden was 31-46 microcuries per kilogram The peak titre was reached for both antigens within eleven days in both control and exposed dogs. This amount of exposure did not accelerate the rate of decline of ... |
|
| METABOLISM OF PROTEIN, AMINO ACIDS AND AMMONIA IN PATIENTS WITH LIVER DISEASE. |
MAY 1964 |
|
| Authors:
George J. Gabuzda; WESTERN RESERVE UNIV CLEVELAND OHIO SCHOOL OF MEDICINE
|
| Renal function in patients with liver disease (hepatorenal syndromes), and the metabolic responses of man and animals to potassium deficiency and excess were studied. Renal responses to potassium loading were studied in salt-fed and salt-deprived normal subjects and in patients with ascites who are avid sodium retainers. The renal responses are conditioned by the degree of renal sodium conservation. Patients with ascites have abnormal responses to KC1 loading. They show ... |
|
| THE ETIOLOGY AND PROPHYLAXIS OF INFECTIOUS HEPATITIS |
26 NOV 1963 |
17 pages |
| Authors:
James G. Crawford; PFIZER (CHAS) AND CO INC TERRE HAUTE IN DEPT OF BIOLOGICS RESEARCH
|
| The incidence of hemagglutinins to monkey erythrocytes was surveyed in over 1,000 sera from normal, Non-IH liver disease and IH disease donors. No significant difference in incidence or titer of warm or cold agglutinins that would distinguish infectious hepatitis from control specimens is confirmed. In a second phase of this study, methods for inactivating the nonspecific agglutinins (NSA) were developed in order to determine if the NSA masked a disease-specific ... |
|
| A STUDY OF SERUM HEPATITIS FROM STORED PLASMA. |
01 AUG 1963 |
|
| Authors:
Allan G. Redeker; UNIVERSITY OF SOUTHERN CALIFORNIA LOS ANGELES SCHOOL OF MEDICINE
|
| A prospective controlled study of the frequency of hepatitis following the transfusion of pooled human plasma stored for six months in the liquid state at 30 - 32 Centigrade has been initiated. Surgical Service patients who receive only plasma and no other human blood products are the subjects of the study. The control solution, administered in a double-blind fashion, is five per cent human albumin solution. All patients allocated to ... |
|
| ELECTRON MICROSCOPE STUDY ON THE INFECTIOUS HEPATITIS. |
14 NOV 1961 |
|
| Authors:
Gonpachiro Yasuzumi; NARA MEDICAL COLL KASHIHARA CITY (JAPAN)
|
|
| ELECTRON MICROSCOPE STUDY ON THE INFECTIOUS HEPATITIS. |
14 AUG 1961 |
|
| Authors:
Gonpachiro Yasuzumi; NARA MEDICAL COLL KASHIHARA CITY (JAPAN)
|
|
Reports by Keyword(s)
*HEPATITIS
