| Out-of-Hospital Combat Casualty Care in the Current War in Iraq |
Feb 2009 |
7 pages |
| Authors:
Robert T De Gerhardt; Robert A Lorenzo; Jeffrey Oliver; John B Holcomb; James A Pfaff; UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD
|
 | We describe outcomes for battle casualties receiving initial treatment at a US Army consolidated battalion aid station augmented with emergency medicine practitioners, advanced medic treatment protocols, and active medical direction. Battalion aid stations are mobile facilities integral to combat units, providing initial phases of advanced trauma life support and then evacuation. The setting was a forward base in central Iraq, with units engaged in urban combat operations. |
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| Sickle Cell Trait and Fatal Exertional Heat Illness: Implications for Exercise-Related Death of Young Ddults |
22-Oct-2008 |
69 pages |
| Authors:
John A Kark; John W Gardner; Frank T Ward; Renu Virmani; UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD
|
| Objectives: 1) Analyze specific mortality rates to characterize sickle cell trait as a risk factor for exercise-related death. 2) Examine factors important to prevent EHI among all recruits. 3) Interpret results of a controlled prospective intervention to prevent EHI on exercise-related mortality for recruits. 4) Provide practical recommendations to reduce exercise-related death in young adults with or without sickle cell trait. |
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| Reset and Healing Break-Out Session Summary. Warfighter Nutrition: Advanced Technologies and Opportunities |
16-Jul-2008 |
7 pages |
| Authors:
UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD
|
| Clinical Recommendations: *All hospitalized DOD personnel should be given multiple vitamin / essential fatty acid supplements. The doses should be similar to that which is provided to NASA astronauts. *ASD Health Affairs should have staff assigned to collect knowledge of all clinical DOD studies to prevent duplication and promote coordination. |
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| A Lessons-Learned Legacy |
01-Feb-2008 |
3 pages |
| Authors:
Howard R Champion; UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD
|
| The combat casualties of war have always provided society with substantial advances in knowledge and care of injury. The casualties of Operations Iraqi Freedom (OIF) and Enduring Freedom (OEF) are no exception. A serious sampling of the lessons learned from caring for these wounded soldiers and Marines and subsequent research initiatives are published in this Supplement to the Journal of Trauma as a result of the endeavors of the young ... |
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| Biobehavioral Correlates of Depression in Reaction to Mental and Physical Challenge |
07 MAR 2007 |
112 pages |
| Authors:
Ali A. Weinstein; UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD
|
| Depression is the most common mental disorder in the United States. Individuals with depression are at an increased risk of cardiovascular morbidity and mortality. However, little is known regarding the possible mechanisms to explain this relationship. One of the possible pathways includes exaggerated responsiveness to challenge in depressed individuals. The overarching hypothesis of this investigation is that depressed individuals display higher reactivity to mental and physical challenge than non-depressed controls. ... |
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| Ultrasound Guidance as a Rescue Technique for Peripheral Intravenous Cannulation |
14 SEP 2006 |
16 pages |
| Authors:
Nancy L. Pappas; Terese E. Michaud; Russell M. Wolbers; James C. Steward; Thomas A. Fevurly; Timothy J. Samolitis; Bruce A. Shoneboom; Dorraine D. Watts; UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD
|
| Peripheral intravenous (W) cannulation can be difficult to perform using the traditional landmark or visual/palpation technique in patients with access difficulties such as deep, sclerotic, small, or fragile veins. Ultrasound guidance has shown efficacy in expediting the cannulation of central veins, but there is limited information on its utility in facilitating cannulation in peripheral veins, particularly for patients with difficult access. The purpose of this study was to compare the ... |
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| The Safety of Desiccated Baralyme(TM) in the Narkomed-M Anesthesia Machine: The Effect of Isoflurane and Sevoflurane at Low and High Flow O2 on Absorbent Temperature |
AUG 2006 |
26 pages |
| Authors:
Brian M. Glenn; James A. Smith; Mark E. Bucher; Richard F. Huff; Paul W. LeSaint; Wanda J. Stone; Susan M. Perry; Dorraine D. Watts; UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD
|
| Objective: To determine the clinical safety of using partially desiccated Baralyme(TM) in a Narkomed-M anesthesia machine by measuring the maximum temperature within the absorbent and time to maximum temperature under standard OR conditions. Methods: Four experimental conditions were set using sevoflurane (experiment) vs. isoflurane (control) at low (3L) vs. high (5L) O2 flows. Baralyme was partially desiccated by 12 hours high-flow air to 10.8% moisture. Results: Twenty three trials showed ... |
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| Behavioral and Biological Effects of Housing Conditions and Stress in Male Rats - Relevance to Heart Disease |
AUG 2006 |
104 pages |
| Authors:
Sarah T. Shafer; UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD
|
| The present experiment examined the effects of environmental enrichment and stress on behavioral and biological measures relevant to cardiovascular disease risk (i.e. plasma corticosterone levels elevated plus maze locomotor activity in an open field chamber body weight and food consumption and heart morphology). Seventy-two Sprague-Dawley rats were raised in enriched environments (social or social and physical enrichment) or non-enriched environments for a total of 48 days. Half of the animals ... |
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| Perioperative Clinical Nurse Specialist Role Delineation: A Systematic Review |
JUN 2006 |
356 pages |
| Authors:
Lisa M. Cole; Theodore J. Walker; Kelly C. Nader; Dennis E. Glover; Laura E. Newkirk; UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD
|
| A clearly defined role of the Perioperative Clinical Nurse Specialist (PONS) is not identified. The purpose of this study was to provide recommendations for a delineated role of the PONS that will provide role clarity and practice guidance. A systematic review of the literature was conducted utilizing an adaptation of Rheiner's "Role Theory Framework for Change". The initial search yielded 6374 articles. Thirteen percent (859) of the articles met inclusion ... |
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| Dissociation of Hexavalent Chromium from Sanded Paint Particles into a Simulated Lung Fluid |
JUN 2006 |
117 pages |
| Authors:
Steven H. Lange; UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD
|
| Chromate-containing paint coatings are the primary means of protecting an aircraft surface from corrosion in the US military. Studies clearly link chromate exposure to human lung cancer. However, the few studies of the painting industry suggest that chromate exposure from paint particles does not increase the risk of lung cancer. Even fewer studies have evaluated sanding of chromate containing paint layers, and data suggests that sanders have an increased risk ... |
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| Effects of Dexmedotomidine in the Coronary Artery Bypass Graft (CABG) Patient: A Pilot Study |
14 APR 2006 |
17 pages |
| Authors:
Sara C. Armour; James B. Goode; Collis H. Lang; Leas R. Tilley; John Craig; Bruce A. Schoneboom; Doraline Watts; UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD
|
| Postoperatively, CABG patients remain intubated requiring sedation and pain management. Propofol is a commonly used sedative but requires concomitant analgesic use. Dexmedetomidine (DEX) is an alpha-2 agonist providing both sedative and analgesic properties. The purpose of this study was to compare Propofol to DEX infusions to determine differences in amount of post-op pain medication used, intubation time, and Cardiothoracic Unit (CTU) time. |
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| Workplace Preparedness for Terrorism |
2006 |
51 pages |
| Authors:
Robert J. Ursano; UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD
|
| Comprehensive workplace preparedness for terrorism must address and integrate the psychological and behavioral aspects of terrorism preparedness and response in order to address issues of human continuity. Recognizing the beliefs and attitudes that influence behavior and drive behavioral change is essential if organizations are to effectively commit time to educate employees about preparedness and to practice preparedness behaviors. Understanding human continuity issues must also inform development of the interventions that ... |
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| The Molecular Basis of Canavan Disease: Aspartoacylase Enzyme Characteristics |
2006 |
200 pages |
| Authors:
Jeremy R. Hershfield; UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD
|
| Mutations in the gene for aspartoacylase (EC 3.5.1.15; ASPA), which catalyzes deacetylation of N-acetyl-L-aspartate (NAA), correlate with Canavan Disease (CD), a neurodegenerative disorder usually fatal during childhood. Defective ASPA activity has been linked to characteristically elevated NAA levels in the urine of CD patients, and ASPA knockout mice and ASPA deletion rats display CD-like symptoms. While efforts have focused on treating CD, there is limited evidence to support ASPA protein ... |
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| Improved Detection Sensitivity of a Biological Simulant: Delivery of Chemical Labels to the Cell Surface by Adsorption of Polyethyleneimine Derivatives |
NOV 2005 |
14 pages |
| Authors:
David A. Grahame; Simonida Gencic; Burt V. Bronk; UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD
|
| The use of biological simulants in testing detection/identification instruments often employs antibodies to quantify the amount of simulants or sometimes as an integral part of the detection suite. At present, the bacterium Pantoea agglomerans (formerly Erwinia herbicola, Eh) is an approved vegetative agent simulant, however, Eh detection sensitivity is disappointing in standard methods such as ELISA, using various anti-Eh antibody preparations, including antibodies that have been raised against surface- modified ... |
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| Uniformed Services University of the Health Sciences Journal. 2004/5 Edition |
30 OCT 2005 |
680 pages |
| Authors:
Mary A. Dix; UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD
|
| A recognized vital and integrated component of the Military Health System (MHS), USU continues to provide essential support to Force Health Protection through its unique training centered in preventive medicine and combat-related health care. In accordance with strategic guidance, the University continues to successfully focus on: RELEVANCE - the critical, or core relevance, of its essential mission to provide continuity, leadership, and responsiveness to the special needs of the MHS; ... |
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| The Immunogenicity of a Biological Simulant: Strategies for the Improvement of Antibody-Based Detection |
01 OCT 2005 |
13 pages |
| Authors:
David A. Grahame; Simonida Gencic; Burt V. Bronk; UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD
|
| When biological simulants are used for testing detection/identification instruments, antibodies are often employed to quantitate the amount of simulants or sometimes as an integral part of the detection suite. The bacterium Pantoea agglomerans (formerly Erwinia herbicola, Eh) presently is used to simulate vegetative biological agents, however, anti-Eh antibodies of high affinity and specificity are needed. Therefore, we have characterized rabbit antibodies raised against native Eh and Eh chemically modified with ... |
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| Using Focus Groups in the Refinement of a Research Tool |
08 JUN 2005 |
22 pages |
| Authors:
Tara N. Constantine; Joanna Bourne; Sandra Bibb; Linda Wanzer; Cheryl Reilly; UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD
|
| As part of a larger research study, two graduate students used focus groups to collect data to assist in the refinement of a tool (Patient Assessment Questionnaire, PAQ) to identify the sociodemographic characteristics associated with the presence of body piercings in elective surgery patients. Two focus groups were convened. The first group consisted of perioperative nurse experts who were asked to validate the content in the PAQ. The second group ... |
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| Operating Room Telephone Microbial Flora |
02 JUN 2005 |
32 pages |
| Authors:
J. Nelson; A. Bivens; A. Shinn; L. Wanzer; C. E. Kasper; K. McIlwain; J. Bruton; S. Bibb; UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD
|
| There are approximately 500,000 surgical site infections per year in the United states. The purpose of this study was to determine if the bacteria most frequently involved in Surgical Site Infections (SSI) could be found on telephones in the Operating Room (OR). A total of 26 cultures were taken from telephones within 14 operating rooms and two sub-sterile rooms at a large teaching medical center. Bacteria were identified using standard ... |
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| Use of Focus Groups in the Development of a Piercing Assessment Questionnaire |
JUN 2005 |
24 pages |
| Authors:
Tara N. Constantine; Joanna Bourne; UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD
|
| As part of a larger research study, two graduate students used focus groups to collect data to assist in the development of a tool (Patient Assessment Questionnaire-PAQ) to identify the sociodemographic characteristics associated with the presence of body piercings in elective surgery patients. Two focus groups were convened. The first group consisted of perioperative nurse experts who were asked to validate the content in the PAQ. The second group consisted ... |
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| Operating Room Telephone Microbial Flora |
24 MAY 2005 |
32 pages |
| Authors:
Jason Nelson; Antoinette M. Shinn; Ava Bivens; UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD
|
| There are approximately 500,000 surgical site infections per year in the United States. The purpose of this study was to determine if the bacteria most frequently involved in Surgical Site Infections (SSI) could be found on telephones in the Operating Room (OR). A total of 26 cultures were taken from telephones within 14 operating rooms and two sub-sterile rooms at a large, teaching, medical center. Bacteria were identified using standard ... |
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| Hypoxia-Inducible Factor Prolyl Hydroxylases are Oxygen Sensors in the Brain |
01 MAR 2005 |
126 pages |
| Authors:
Clifton Dalgard; UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD
|
| In mammalian cells, molecular oxygen is a requirement for normal growth, metabolism, and survival. Tissues in which oxygen demand surpasses oxygen supply become hypoxic and cannot maintain normal function. Thus, the ability to sense oxygen levels is necessary for an organism to survive and thrive in changing environmental and physiological conditions. HIF-1 is a transcription factor complex that is essential and central to several cellular and systemic adaptations to hypoxia. ... |
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| Perspectives of Retired Air Force Nurse Anesthesia Leaders |
11 JAN 2005 |
24 pages |
| Authors:
David L. Perkins; Robert E. Bland; UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD
|
| Current military and civilian CRNA history papers do not have a United States Air Force focus. This study expanded the current history of roles, relationships, and techniques of the CRNA professionals. The purpose of this qualitative study was to historically describe the roles, professional relationships, and techniques among nurse anesthetists in the Air Force since 1951. CRNAs who served on active duty in the Unites States Air Force were included ... |
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| Pollution of Ambient Air by Volatile Anesthetics: A Comparison of Four Anesthetic Management Techniques |
11 JAN 2005 |
20 pages |
| Authors:
Joy C. Barberio; Jason D. Bolt; William J. Craig; Paul N. Austin; UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD
|
| Chronic exposure to waste anesthetic gas (WAG) may lead to health problems. The purpose of this study was to compare WAG concentrations resulting from four combinations of FGF and vaporizer settings during a simulated intravenous induction where the anesthetic is deepened using a volatile anesthetic delivered via mask ventilation prior to intubation. Using lung model, WAG was sampled three times each using four different combinations and three volatile anesthetics: 3% ... |
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| Imposed Work of Breathing of Airway Adjuncts |
16 DEC 2004 |
22 pages |
| Authors:
Joseph C. Skinner Jr.; William D. Gilmer; Brian A. Molloy; Gary A. Wells; Paul N. Austin; UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD
|
| This bench study investigated the imposed work of breathing (WOB(I)) of an endotracheal tube (ETT), Laryngeal Mask Airway (LMA(R)), Streamlined Liner of the Pharyngeal Airway (SLIPA (R)), and Cobra Perilaryngeal Airway (CobraPLA(R)). A surrogate measure of imposed work maximum negative inspiratory pressure (MNIP), was used as the primary measure. Pressure-volume (PV) curves were compared qualitatively. A spontaneous breathing simulator was used to generate simulated spontaneous breaths. The devices were placed ... |
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| Readiness Estimate and Deployability Index for Air Force Nurse Anesthetists |
13 DEC 2004 |
20 pages |
| Authors:
Mark A. Stevenson; Robert B. Scholes; Barbara Sylvia; Teresa Dremsa; Paul N. Austin; UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD
|
| Air Force (AF) Certified Registered Nurse Anesthetists (CRNAs) play an important role in the support of the Global War on Terror. The purpose of the present investigation was to use an AF CRNA specific modification of the Readiness Estimate and Deployability Index revised for Air Force Nurses to assess readiness for deployment. Dimensions included (1) clinical competencies, (2) operational competencies, (3) soldier survival skills, (4) personal/ psychosocial/physical readiness, (5) leadership ... |
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| The Use of Ultrasound for Placement of Intravenous Catheters |
13 DEC 2004 |
20 pages |
| Authors:
Said Acosta; UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD
|
| Ultrasound has been used to aid cannulation of veins of the neck, chest, antecubital fossa as well as the femoral vein. This investigation compared the traditional method of peripheral intravenous (IV) cannulation of veins of the hands and forearms to ultrasound-guided (IV) cannulation of these veins. Subjects were adults of either gender who reported a history of difficult IV cannulation or, based on examination, suspected to be to be difficult ... |
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| Prospective and Retrospective Testing of High Prevalence HIV-1 Serum and Blood Using Rapid and Conventional Technology |
DEC 2004 |
7 pages |
| Authors:
Darrell E. Singer; Linda Hird; Jamie Bulken-Hoover; Ginamarie Foglia; R. D. Royster Iv.; Jennifer A. Malia; Eva K. Calero; Warren Sateren; Merlin L. Robb; Deborah L. Birx; Nelson L. Michael; UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD
|
| We have conducted studies with existing rapid HIV-1 serology technology for applicability in military operations. Studies on fresh and frozen serum and differing HIV sub- types have been conducted in both the research and field environments. Testing has been compared to reference technology for calculation of operating characteristics. Conclusion: Rapid HIV-1 testing technology is an evolving field subject to market demands. Several tests exist that support warfighter use in the ... |
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| The Medical Triage Assistant: A Diagnostic Sensor Suite for Far Forward Medical Care |
01 SEP 2004 |
|
| Authors:
Geoffrey S. Ling; Adrian Urias; Ronalee Lo; Catherine Yun; Eleanor Lee; Jeffrey Becker; Sandy Bogucki; Peter Rhee; Hasan Alam; James Ecklund; UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD
|
 | A new method for obtaining critical physiologic data in combat injured war fighters is presented. The device is called the Medical Triage Assistant (MTA). This method uses a wearable glove format that has embedded sensors for electrocardiogram (ECG), pulse oximetry and body temperature. Data is collected in real-time. Results are presented applying this device to measure physiologic changes in an anesthetized pig model subjected to hypoxia, cold induced hypothermia, and ... |
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| Uniformed Services University of the Health Sciences Journal 2003 Edition |
18 AUG 2004 |
659 pages |
| Authors:
Mary A. Dix; UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD
|
| This 2003 Edition of the USU Journal documents that the Uniformed Services University of the Health Sciences (USU) continues to meet, or exceed, its Congressionally established and Department of Defense directed mission to provide continuity and leadership and ensure medical readiness and continuing education for the Military Health System (MHS) through the provision of career- oriented, uniquely trained physicians, advanced practice nurses and scientists and specialized educational training, exercises and ... |
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| Correlation Between Measured Ambient Airborne Particulate Matter (PM10) Concentrations and Ophthalmologic Disease Non-Battle Injury (DNBI) Rates in Active Duty Personnel Deployed to a US Military Base in Central Command (CENTCOM) Between October 1999 and |
JUN 2004 |
26 pages |
| Authors:
Monica U. Selent; UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD
|
| Previous studies have suggested an association between ambient airborne particulate matter (PM 10) concentrations and adverse ophthalmologic conditions. To determine a correlation between PM 10 and Ophthalmologic Disease, Non-battle Injuries (DNBI), datasets currently available on active duty personnel deployed to a US military base in Central Command (CENTCOM) were collected and analyzed for the period between October 1999 and September 2001. Weekly averages of ophthalmologic, non-ophthalmologic, and total DNBI rates ... |
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| The Delphi Technique Used in Laser Incident Surveillance |
JUN 2004 |
76 pages |
| Authors:
Krystyn R. Clark; UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD
|
| Surveillance is an important component of trend analysis in laser incident reporting. Proper surveillance of workplaces in which laser systems are used, personnel at risk of exposure and evaluation of laser injuries can lead to better injury prevention and rapid medical treatment of laser injuries that occur. Ultimately, the prevention laser injuries helps ensure a healthier workforce. Current databases that collect laser incident data were not designed for surveillance of ... |
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| Orally Administered IL-6 Induces Elevated Intestinal GM-CSF Gene Expression and Splenic CFU-GM |
30 MAR 2004 |
7 pages |
| Authors:
F. M. Rollwagen; T. A. Davis; Y. Y. Li; N. D. Pacheco; X. L. Zhu; UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD
|
| Orally administered interleukin (IL)-6 has been shown to be of benefit in eliminating Campylobacter infection and in preventing sepsis following hemorrhage. In related experiments, it was seen that proliferating cells were found in the spleens of untreated mice given IL-6 by oral gavage. Injection of the DNA label, BrdU, showed that significant proliferation began at 4 h and peaked at 24 h in the splenic red pulp of animals given ... |
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| Detection of Bartonella bacilliformis by Real-Time PCR in Naturally Infected Sand Flies |
04 MAR 2004 |
97 pages |
| Authors:
Sofia Romero; UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD
|
| Evidence incriminating phlebotomine sand flies as vectors of Bartonella bacilliformis, which causes bartonellosis, has not been proven beyond doubt. Our research was designed to strengthen this hypothesis. In addition, we developed a Real- Time PCR method capable of detecting as little as 100fg of Bartonella DNA in sand flies. Twelve primers were designed using TaqMan Probe/ Primer Data and tested. Lutzomyia verrucarum sand flies were collected from an endemic focus ... |
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| The Influence of Platelet-Derived Growth Factor and Fibroblast Growth Factor 2 on Oligodendrocyte Development and Remyelination |
2004 |
153 pages |
| Authors:
Joshua C. Murtie; UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD
|
| Multiple sclerosis (MS) is a demyelinating disease of the central nervous system (CNS) characterized by repeated episodes of autoimmune-mediated demyelination. Symptoms of the disease range from loss of vision to paralysis with each episode resulting in a decreased remyelination response. If remyelination does not occur, bare axons will not be able to function properly either by inefficient saltatory conduction or by degeneration resulting from a lack of myelin. This study ... |
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| A Comparison of Eating Patterns Across Two Obesity Treatments: Behavior Therapy vs. Behavioral Choice Treatment |
06 OCT 2003 |
125 pages |
| Authors:
Kristy L. Morris; UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD
|
| Traditional obesity treatments have demonstrated successful short- term, but not long-term, weight loss. Behavior Therapies (BT) typically prescribe moderate kilojoule reduction and eating rules that promote a "dieting mentality." Behavioral Choice Treatment (BCT), which emphasizes mild kilojoule reduction and flexibility in eating has previously demonstrated greater weight loss maintenance compared to BT. This study compares eating patterns across treatments to explore differences related to weight loss. Thirty-two obese women, randomly ... |
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| My Body, My Weight: Body Perception Among African American and Caucasian First-Graders and Their Parents |
02 OCT 2003 |
123 pages |
| Authors:
Dawnavan S. Davis; UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD
|
| Research suggests that body dissatisfaction can develop by first- grade and girls tend to be less satisfied with their bodies compared to boys. However, no studies have examined the effects of race and gender and parental factors on body image among firstgraders. Fifty-eight child/parent dyads participated in the current study. Children were given a silhouette measure to assess body image. The FRS, EDI, White/Black Racial Identity Scales, and AAAS were ... |
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| The Uniformed Services University of the Health Sciences Journal 2002 Edition Learning to Care for Those in Harm's Way |
25 AUG 2003 |
|
| Authors:
UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD
|
|
| Localization and Expression of the Proto-Oncoprotein BRX in the Mouse Brain and Pituitary |
13 AUG 2003 |
80 pages |
| Authors:
David O. Eddington; UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD
|
| A new member of the Dbl family of oncoproteins was discovered in breast cancer tissue extracts. This novel protein, designated Brx, contains an estrogen-receptor binding motif and is highly expressed in hormone-responsive breast tissue. Due to its ability to augment ligand-dependent activation of estrogen receptors, we analyzed the expression of Brx in the adult mouse brain and pituitary. Results indicated that Brx is expressed in specific regions of the brain ... |
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| Digital Mammography Breast Dosimetry Using Copper-Doped Lithium Fluoride (LiF:MCP) Thermoluminescent Dosimeters (TLDs) |
18 JUN 2003 |
62 pages |
| Authors:
John J. Tomon; UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD
|
| The determination of mean glandular dose (MGD) to the breast is an essential aspect of mammography equipment evaluations and exposure controls. The American College of Radiology (ACR) Quality Control Manual outlines the procedure for MGD determination in screen-film mammography based upon conversions of entrance skin exposures (ESEs) measured with an ionization chamber (IC). The use of digital mammography has increased because of the need for improved object resolution and tissue ... |
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| Effects of Pregnancy on the Army Physical Fitness Test |
MAY 2003 |
44 pages |
| Authors:
Stacy E. Usher; UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD
|
| The purpose of this study was to determine the actual and perceived amount of time needed for the postpartum soldier to return to pre-pregnancy fitness condition as evidenced by APFT scores before and after pregnancy. There were three questions addressed in this study. First, what effect does pregnancy have on physical fitness levels as demonstrated by APFT scores? Second, how long does it take the postpartum soldier to return to ... |
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| Weight Management Behaviors Used by Active Duty Nurses to Maintain Compliance With Military Weight Control Standards |
MAY 2003 |
42 pages |
| Authors:
Joseph M. Candelario; UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD
|
| It has been suggested that the stress of being in compliance with standards for weight control in the military may cause some individuals to pursue unhealthy weight management behaviors. These behaviors could have an adverse effect on fighting strength and can undermine the mission of the military. The objective of this study was to describe the weight control/loss behaviors of active duty service members to maintain compliance with military weight ... |
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| Cullin 5 Expression in the Rat: Cellular and Tissue Distribution, and Changes in Response to Water Deprivation and Hemorrhagic Shock |
28 FEB 2003 |
157 pages |
| Authors:
Thomas E. Ceremuga; UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD
|
| Protein degradation by ubiquitination and the 26S proteasome is used to modulate the steady-state levels of proteins and to regulate cellular processes. Proteins become targets of the proteasome by covalent attachment of polyubiquitin chains, which requires three main enzymes (E1, E2, and E3). It is the E3 ubiquitin ligases that control the selection and specificity of substrate ubiquitination. Cullin-5 (Cul-5), a member of the cullin family of E3 ubiquitin ligases, ... |
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| The Epidemiology of Malaria in Belize, 1989-1999 |
FEB 2003 |
285 pages |
| Authors:
Shilpa Hakre; UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD
|
| Retrospective analyses were conducted to describe the epidemiology of malaria in Belize over a 10-year period and to determine if environmental factors influenced the incidence of malaria at macro- and micro-scales. The purpose was to contribute to the current body of knowledge regarding malaria transmission in Belize, which may aid in region-specific malaria control efforts. Malaria data were obtained from the National Malaria Control Program's National Malaria Database. Malaria rates ... |
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| The Effect of Feedback on Penile Tumescence in Sexually Functional Men |
06 JAN 2003 |
216 pages |
| Authors:
Nathan W. Galbreath; UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD
|
| Male erectile disorder (ED) impacts the sexual functioning of ten to twenty million men in the United States. Erectile disorder, as withother sexual dysfunctions, may be caused by, or associated with a number of diseases that impact the cardiovascular and nervous systems. However, men who have few physical problems may also experience the disorder due to psychological factors. Men who suffer from ED due to psychogenic factors are believed to ... |
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| Effects of Stress and Relaxation on Time Perception |
2003 |
215 pages |
| Authors:
Bonnie R. Chavez; UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD
|
| Changes in time perception during and following experiences of stress and relaxation are commonly reported, but little is known about the direction and nature of any time perception changes. In this experimental study, men and women ages 18 to 79 were randomly assigned to one of three conditions: stress (n = 39) - speech preparation and presentation, relaxation (n = 38) - a progressive muscle relaxation exercise, or control (n ... |
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| Structural and Functional Studies on the Fusion and Attachment Envelope Glycoproteins of Nipah Virus and Hendra Virus |
2003 |
193 pages |
| Authors:
Katharine N. Bossart; UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD
|
| Nipah virus (NiV) and Hendra (HeV) virus are emerging, biosafety level 4 paramyxoviruses responsible for fatal zoonotic infections of humans from pigs and horses, respectively, and are the prototypic members of a new Paramyxovirinae genus called Henipavirus. These enveloped, negative-sense RNA viruses infect cells through a pH-independent membrane fusion event mediated through the actions of their attachment (G) and fusion (F) envelope glycoproteins, which are also the principal antigens to ... |
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| Induction and Characterization of Immune Responses in Small Animals Using a Venezuelan Equine Encephalitis Virus (VEE) Replicon System, Expressing Human Immunodeficiency Virus Type 1 (HIV-1) Envelope Genes |
2003 |
89 pages |
| Authors:
Jennifer M. DeVol; UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD
|
| Human immunodeficiency virus type 1 (HIV-1) is the lentivirus responsible for the Acquired Immunodeficiency Syndrome (AIDS) pandemic. Currently, no approved vaccine exists to combat this global human health threat. One approach is to develop a vaccine that induces neutralizing antibodies. To date, the most promising platforms used for induction of neutralizing antibodies against HIV-1 is the Venezuelan equine encephalitis virus (VEE) replicon system. The studies detailed herein have characterized certain ... |
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| 810 NM Light Treatment of Acute Spinal Cord Injury Alters the Immune Response and Improves Axonal Regeneration and Functional Recovery |
2003 |
154 pages |
| Authors:
Kimberly R. Byrnes; UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD
|
| Spinal cord injury (SCI) results in substantial and often permanent impairment of function due to the lack of regeneration of damaged axons. Despite vigorous research, no cure for SCI has been found. Light therapy (LT), through the absorption of light by target tissue, improves healing in a number of injury models. However, no study to date has assessed the ability of LT to facilitate the regeneration of specific spinal cord ... |
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| The Military Deployment Human Exposure Assessment Study (MDHEXAS): Blood and Urine Exposure Biomarkers as Environmental Surveillance Tools for Assessing Military Personnel Exposure to Chemicals During Deployment to Camp McGovern, Bosnia |
2003 |
194 pages |
| Authors:
UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD
|
| Currently the Department of Defense (DoD) does not use exposure biomarkers to measure environmental exposures to chemicals. Blood and urine exposure biomarkers for volatile organic compounds (VOC), selected heavy metals, depleted uranium (DU), and chemical warfare agents are currently available but have not been field tested or validated in military deployments as a tool to document exposures by the DoD. The Military Deployment Human Exposure Assessment Study, a prospective cohort ... |
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| Technologies for Genome-Wide Identification of Stat5 Regulated Genes |
2003 |
284 pages |
| Authors:
Matthew J. LeBaron; UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD
|
| Each year more than one million new cases of breast cancer are diagnosed worldwide and an estimated 370,000 women die from breast cancer. Although the vast majority of fatal breast cancer cases involve metastatic spread of the primary tumor, the formation of metastases is still a poorly understood, complex process. Identifying the early molecular changes that facilitate metastasis of breast cancer will lead to new molecular targets for prevention of ... |
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