| Development of Technologies for Early Detection and Stratification of Breast Cancer |
Oct 2012 |
38 pages |
| Authors:
David R Walt; Daniel Chiu; Charlotte Kuperwasser; Gail Sonenshein; Rachel Buchsbaum; TUFTS UNIV MEDFORD MA
|
 | The overall goal of this work is to develop ultra-sensitive detection techniques to identify a panel of new biomarkers and indicators with diagnostic and predictive value in breast cancer. During year 1, we identified candidate breast cancer biomarkers and developed ultra-sensitive assays for several of them. Two different miRNA single molecule assay approaches have also been investigated and both showed promise for achieving similar ultrasensitive data using miRNA as targets. ... |
|
| Dynamic Camouflage Materials Based on Silk-Reflectin Chimeras |
01 Aug 2012 |
6 pages |
| Authors:
Fiorenzo Omenetto; David L Kaplan; TUFTS UNIV MEDFORD MA
|
| Reflectins are a unique group of structural proteins involved in dynamic camouflage systems in marine organisms. Initial cloning of reflectins, followed by thin film displays of the bioengineered protein, suggest interesting optical features when the recombinant protein is appropriately organized. These useful features include self-assembly and coloration patterns associated with material interference patterns. The goal of this project is to examine the fundamental relationships between reflectin chemistry, assembly, organization and ... |
|
| Mexico's National Interest in Drug Profits |
03 May 2011 |
36 pages |
| Authors:
James H Raymer; TUFTS UNIV MEDFORD MA
|
| Mexico currently has no governmental consensus to willingly renounce the enormous drug profits flowing into the country from sales in the United States as harmful to Mexican national interests. Any U.S. drug control strategy must accept this fact at the outset in determining the prospects for success. Competing interests within the Mexican government prevent the formation of a consensus that drug profits are harmful to Mexico. Mexican presidents have framed ... |
|
| Development and Optimization of Targeted Nanoscale Iron Delivery Methods for Treatment of NAPL Source Zones |
APR 2011 |
134 pages |
| Authors:
Linda Abriola; Andrea Ramsburg; Kurt Pennell; TUFTS UNIV MEDFORD MA
|
| This project was designed to develop and evaluate innovative nanoscale zero valent iron (nZVI) technologies for application to the treatment of dense nonaqueous phase liquid (DNAPL) source zones. An integrated research program, that combined multi-scale laboratory experiments with mathematical modeling, was undertaken: to investigate the transport and reactivity properties of commercially available nZVI systems; to develop and refine novel nZVI encapsulation formations with superior potential for source zone remediation; and ... |
|
| Evaluating the Effects of Interface Disruption Using fNIR Spectroscopy |
28 Feb 2011 |
16 pages |
| Authors:
Robert J Jacob; Leanne M Hirshfield; TUFTS UNIV MEDFORD MA
|
| The primary accomplishment that we achieved during this three year effort was the creation and implementation of a novel usability experiment protocol and a set of machine learning methods that enable us to predict, on the fly, the user state of a given individual. Before we began this research, the majority of brain research, and all fNIRS research could not PREDICT user states. Previous research in non-invasive brain measurement could ... |
|
| Functionalized Silk Materials |
10 Jun 2010 |
8 pages |
| Authors:
David L Kaplan; TUFTS UNIV MEDFORD MA
|
| The significance of the project is that a new family of functional materials and coatings derived from the silk systems will be generated, with the silk component serving as the organizing moiety and the functional domains added to the silk providing enhanced properties for the materials--thus, light weight materials, electronic properties and related features are anticipated through the precise control of functional domains within and on the silk well-defined material ... |
|
| Development of Assessment Tools for Evaluation of the Benefits of DNAPL Source Zone Treatment |
Sep 2008 |
174 pages |
| Authors:
Linda M Abriola; Pierre Goovaerts; Kurt D Pennell; Frank E Loffler; TUFTS UNIV MEDFORD MA
|
| Since its commencement in September 2002, SERDP Project ER-1293 has supported 4 doctoral students at three universities and resulted in over 40 conference proceedings/technical abstracts and over 20 peer-reviewed publications. These presentations and publications, as referenced in this final report, describe various aspects of the research investigations and tools that have been developed to enhance design and assessment of DNAPL source zone treatment. In general, research in ER-1293 has led ... |
|
| Silk Polymer Designs for Improved Expression and Processing |
28 OCT 2007 |
5 pages |
| Authors:
David L. Kaplan; TUFTS UNIV MEDFORD MA
|
| Silk fibers formed by insects and spiders are noted for their remarkable mechanical properties as well as their durability and biocompatibility. The exceptional solubility in vivo (20-30% w/v) of these proteins is dictated by both the need to produce solid fibers with a high packing fraction and the high mesogen concentration required for lyotropic liquid crystalline spinning, while also achieving high end mechanical properties for survival (orb webs, cocoons). Combining ... |
|
| Detecting Natural Versus Unnatural DNA |
OCT 2007 |
16 pages |
| Authors:
Carla Brodley; Lenore Cowen; Donna Slonim; Jonathan Eisen; TUFTS UNIV MEDFORD MA
|
| We have developed computational pipeline that compares a target genome with related genomes and find regions that have been potentially engineered. Our pipeline compares the target genome with related genomes and finds "unique" genes that have no homologs. These "unique genes" can then be tested for other criteria like DNA composition to narrow down the list of potential engineered genes. |
|
| Automatic Detection of Covert Channels in Networks |
MAY 2007 |
14 pages |
| Authors:
C. E. Brodley; TUFTS UNIV MEDFORD MA
|
| A covert channel is a mechanism that can be used to violate a security policy by allowing information to leak to an unauthorized process. Two types of covert channels exist; storage and timing channels. A storage channel involves the direct or indirect writing of a storage location by one process and the direct or indirect reading of the storage by another process. A timing channel involves a sender process that ... |
|
| Noisy Quantum Communication and Computation |
2006 |
16 pages |
| Authors:
Mary B. Ruskai; TUFTS UNIV MEDFORD MA
|
| Proposals for adiabatic quantum computation generated renewed interest and questions about the adiabatic approximation. We presented a simple proof of the adiabatic theorem in which we showed that the first order correction has the expected dependence on an energy gap; however, determining the time scale needed to ensure a small error may require consideration of higher order terms. We also give a simple new proof of the key gap estimates ... |
|
| Frequency-Domain Optical Mammography |
OCT 2001 |
64 pages |
| Authors:
Serigo Fantini; TUFTS UNIV MEDFORD MA
|
| This research project involves the analysis of a clinical data set of frequency-domain optical mammogram (-150 patients) to assess the performance of this approach to breast cancer detection. The analysis of the breast images is complemented by theoretical and experimental studies to characterize the proposed algorithms of image processing. During the second year of this research project, we have significantly refined the perturbation approach that we started developing at the ... |
|
| An Object Description Language for Distributed Discrete Event Simulations |
24 May 2001 |
458 pages |
| Authors:
Andrews; Harold G II; TUFTS UNIV MEDFORD MA
|
| Digital simulation is a useful tool for developing a better understanding of physical or hypothetical systems. It has been used with great success since the advent of the digital computer in such varied fields as weather prediction, planning military operations, and training. As digital computers become more capable and network communications systems more prevalent, the notion of synergistically combining the two to perform distributed simulation has led to some tremendous ... |
|
| Workstation Cluster for Simulations of Quantum Lattice-Gas Automata and Entropic Lattice Boltzmann Models |
FEB 2001 |
8 pages |
| Authors:
Bruce M. Boghosian; TUFTS UNIV MEDFORD MA
|
| This document is the final report for AFOSR Grant F49620-01-1-0456, 'Workstation Cluster for Simulations for Quantum Lattice-Gas Automata and Entropic Lattice Boltzmann Models'. Under the terms of this grant, a workstation cluster was purchased by Professor Bruce Boghosian of the Department of Mathematics at Tufts University in order to carry out large-scale simulations in support of his other AFOSR project F49620-01-1-0385, 'Quantum Lattice-Gas Automata and Hydrodynamics', which was fund by ... |
|
| Frequency-Domain Optical Mammograph |
OCT 2000 |
31 pages |
| Authors:
Sergio Fantini; TUFTS UNIV MEDFORD MA
|
| This research project involves the analysis of a clinical data set of frequency-domain optical mammograms (^150 patients) to assess the performance of this approach to breast cancer detection. The analysis of the breast images is complemented by theoretical and experimental studies to characterize the proposed algorithms of image processing. The objective of this research is to identify the strengths and the weaknesses of the current instrument design, and to guide ... |
|
| Simulation of Internal Damping in a Rotating System Supported by Magnetic Bearings |
24 OCT 1999 |
|
| Authors:
Anthony M. Cerminaro; TUFTS UNIV MEDFORD MA
|
 | A rotor with internal damping is a complex dynamic system. An accurate model is required to design and test controllers for supercritical operation. This thesis developed and validated a model for this purpose. An existing rotordynamic Finite Element Method (FEM) model and magnetic bearing simulation, developed by Draper Laboratory, were first compared to actual rotor test data. Correlation of predicted and actual parameters such as ... |
|
| Applications of Photorefractive and Resonant Systems to Optical Signal Processing |
AUG 1999 |
11 pages |
| Authors:
Mark Cronin-Golomb; Venkatapuram S. Sudarshanam; TUFTS UNIV MEDFORD MA
|
| The experiments done in this grant can be broadly classified into two stages. The goal of both these stages was to demonstrate all-optical high-speed turbulence aberration correction through nonlinear optical phase conjugation. The first stage involved the development of a phase conjugate mirror (PCM) based on non-degenerate four-wave-mixiag (NDFWM). Coherent population trapping (CPT) in sodium vapor permitted the use of low intensity cw lasers. The second stage involve the development ... |
|
| Signal to Noise Enhancement for Data use in LVD |
22 JAN 98 |
27 pages |
| Authors:
Richard Barakat; TUFTS UNIV MEDFORD MA
|
| The basic problem addressed under this research is the development of a scheme for deconvolving a set of correlated signals in a multichannel scenario so as to assure signal to noise enhancement. The author addressed this problem during the previous work period via the development of the Karhunen Loeve transformation. The original purpose of this phase was to continue this linear of approach and to some extent this was achieved. ... |
|
| Level Sets and Stochastic Partial Differential Equations |
15 NOV 96 |
7 pages |
| Authors:
Robert C. Dalang; TUFTS UNIV MEDFORD MA
|
| The effort reported on here was primarily aimed at acquiring a better understanding of a broad class of stochastic partial differential equations. The main class of problems was concerned with regularity properties of solutions to stochastic wave equations in one and two spatial dimensions. A second class of problems arose from attempts to understand the flow of information throughout the solution of a linear stochastic wave equation in two spatial ... |
|
| Real Time Holographic Image Processing |
01 NOV 1996 |
76 pages |
| Authors:
Jehad Khoury; Mark Cronin-Golomb; TUFTS UNIV MEDFORD MA
|
| We have proposed homodyne and heterodyne techniques for imaging in a scattering medium. The first technique is based on the principle of the Doppler shift difference of the light which is scattered from an object vs light scattered by the surroundings. We showed that the principle of Doppler shift difference, and the principle of first arriving light are similar. However, in contrast to first light, which requires ultrafast pulses, here ... |
|
| Advanced Instrumentation for Optical Sensor Arrays |
19 APR 96 |
3 pages |
| Authors:
David R. Walt; John Kauer; TUFTS UNIV MEDFORD MA
|
|
| Toward Specification Techniques for Pre-Screen Projection and Other Next-Generation User |
25 SEP 95 |
16 pages |
| Authors:
Robert J. Jacob; TUFTS UNIV MEDFORD MA
|
| We have investigated new languages for describing and implementing next-generation interfaces that might be used in 3-D visualization environments. Working with researchers at NRL Code 5513, we learned about the interfaces they are currently developing and are planning for future work. For current work we examined pre-screen projection and foot control; and we discussed future plans for research in 3-D manipulation, such as 3-D route planning and object-based 3- D ... |
|
| Robust Inversion Methods for Problems in LDV and SAW |
11 JAN 95 |
54 pages |
| Authors:
Richard Barakat; TUFTS UNIV MEDFORD MA
|
| The technical content of the research carried out under the aegis of this contract is covered under two essentially distinct topics: A. Inversion problems associated with surface acoustic waves (SAW) B. Inversion problems associated with laser doppler velocimetry (LDV); signal to noise issues occurring in LDV. |
|
| Stochastic Hyperbolic and Parabolic Partial Differential Equations |
31 JUL 94 |
10 pages |
| Authors:
Robert C. Dalang; N. Frangos; TUFTS UNIV MEDFORD MA
|
| The primary objective was to understand fundamental properties of stochastic partial differential equations. The main results obtained concern properties of level sets of the solution of the one-dimensional wave equation, and regularity properties of the two-dimensional wave equation driven by non- white Gaussian noise. Additional results were obtained in the areas of stochastic optimization and stability of random matrix models. (AN) |
|
| Thermal Behavior of Optical Fibers During the Cooling Stage of the Drawing Process |
91 |
|
| Authors:
Haris Papamichael; Ioannis N. Miaoulis; TUFTS UNIV MEDFORD MA
|
| A general method that predicts the thermal behavior of optical fibers during the cooling stage of the drawing process was developed. The method can be used for thin diameter D< 200 microns, medium (200 microns < D < 500 microns) , and thick (0.5 mm < D < 2mm) single as well as core-clad fibers. A two- dimensional analysis implementing a finite difference method combined with the Karman-Pohlhausen technique was ... |
|
| Ends Versus Means: A Critical Analysis of the Persian Gulf Crisis (1987- 1988) |
AUG 90 |
384 pages |
| Authors:
William J. Luti; TUFTS UNIV MEDFORD MA
|
| An analysis of the 1987-88 Persian Gulf crisis is pursued by examining the relationship between the stated political objectives and the military means (role of force) used in attempting to attain those goals. The purpose of this study is twofold: First, to evaluate the strategic process that led to U.S. involvement in the Gulf and determine how effective that process was in achieving the stated political goals. And second, to ... |
|
| Stress Analysis in Elastic Solids with Many Cracks |
04 DEC 87 |
|
| Authors:
Mark Kachanov; TUFTS UNIV MEDFORD MA
|
| To develop a new method of analysis of many cracks problems in elastic solids that is sufficiently simple and applicable to both two- and three dimensional configurations, and to apply it to a number of practically important problems involving multiple cracking. Such methods has been developed and its accuracy was verified by checking the results against the solutions available in the literature. The new method has been applied to solving ... |
|
| Elastic Interactions of a Crack with Damage and Associated Energy Release Rates |
24 DEC 86 |
|
| Authors:
Mark Kachanov; TUFTS UNIV MEDFORD MA
|
| A new method of analysis of many crack problems has been developed. It is based on the ideas of self-consistency applied to average tractions on individual cracks and yields simple analytical solutions accurate up to quite close distances between cracks. The configuration crack-microcrack array was studied in detail and the effects of stress shielding and stress amplification due to microcracking were investigated. Keywords: Stress intensity factor. |
|
| STUDY OF ELECTROSTATIC EFFECTS ON CONDENSING HEAT TRANSFER. |
MAY 1965 |
|
| Authors:
Harry Y. Choi; John M. Reynolds III.; TUFTS UNIV MEDFORD MA
|
| A study program is presented on the effects of strong electric fields on condensation heat transfer and two-phase flow. It has been confirmed that significant changes in the flow regimes and heat transfer are possible with negligible electrical power expenditure. Over 100 per cent increase in heat transfer has been attained with pressure drop increases which are of the order of 15 per cent in the annular flow regime. These ... |
|
| ON SOLUTIONS OF THE HEAT EQUATION |
21 JUL 1959 |
|
| Authors:
JAMES A. CLARKSON; DAWSON G. FULTON; TUFTS UNIV MEDFORD MA
|
|
| A CHEMICAL AND PHYSIOLOGICAL STUDY OF THE GROWTH HORMONE OF THE ANTERIOR PITUITARY |
22 DEC 1958 |
|
| Authors:
E.B. ASTWOOD; M.S. RABEN; TUFTS UNIV MEDFORD MA
|
|
| FINAL REPT. |
24 AUG 1956 |
|
| Authors:
JOHN JR. RICE; TUFTS UNIV MEDFORD MA
|
|
| INVESTIGATION ON SOME MAGNESIUM HYDRIDES |
01 AUG 1956 |
|
| Authors:
M.JOHN JR. RICE; PETER J. ANDRELLOS; TUFTS UNIV MEDFORD MA
|
|
| BEDROCK GEOLOGY OF MARGUERITE BAY AREA, PALMER PENINSULA, ANTARCTICA |
NOV 1955 |
|
| Authors:
ROBERT L. NICHOLS; TUFTS UNIV MEDFORD MA
|
|
| STUDY OF SPECIFIC ANTIHYDURONIDASES IN SERUM |
15 MAR 1955 |
|
| Authors:
ZAREH HADIDIAN; TUFTS UNIV MEDFORD MA
|
|
| STUDIES IN THE VISUAL DISCRIMINATION OF MULTIPLE UNIT DISPLAYS |
AUG 1954 |
|
| Authors:
GILBERT K. KRULEE; ALESANDER WEISZ; TUFTS UNIV MEDFORD MA
|
|
| ORGANIZATION AND INFORMATION PROCESSING |
AUG 1954 |
|
| Authors:
LEE S. CHRISTIE; TUFTS UNIV MEDFORD MA
|
|
| FINAL REPORT AND ANNOTATED BIBLIOGRAPHY OF OFFICE OF NAVAL RESEARCH. (SYSTEMS ANALYSIS (NAVY)) |
AUG 1954 |
|
| Authors:
TUFTS UNIV MEDFORD MA
|
|
| THE ASSESSMENT OF ATTITUDES RELEVANT TO TEAM PERFORMANCE |
AUG 1954 |
|
| Authors:
LEE S. CHRISTIE; CHARLES S. MORRILL; TUFTS UNIV MEDFORD MA
|
|
| STUDY OF SPECIFIC ANTIHYALURONIDASES IN SERUM |
01 JUL 1954 |
1 pages |
| Authors:
ZAREH HADIDIAN; M.M. MURPHY; J.R. HARRISON; TUFTS UNIV MEDFORD MA
|
|
| DISCRETE SELECTION PROCESSES |
JUL 1954 |
|
| Authors:
MARVIN L. MINSKY; TUFTS UNIV MEDFORD MA
|
|
| HUMAN FACTORS IN ELECTRONICS RELIABILITY |
JUL 1954 |
|
| Authors:
GILBERT K. KRULEE; TUFTS UNIV MEDFORD MA
|
|
| The Reaction of Organosodium Compounds with Uranium Tribromide (With Studies on the Nature and Separation of Reaction Products) |
15 JUN 54 |
50 pages |
| Authors:
Thomas R. Gibb Jr.; Edward J. Goon; Edwin B. Damon; TUFTS UNIV MEDFORD MA
|
| The reaction of sodium in biphenyl, amylsodium, sodium benzophenone ketyl, and sodium naphthalene glycol ether with uranium tribromide is reported. Evidence is given that colloidal uranium is formed in certain instances but is too reactive to be isolated except in partially oxidized form. Reduction by organosodium reagents in the presence of hydrogen gas does not lead to uranium hydride in the reactions studied. Various observations on the reactivity of finely ... |
|
| DISPLAYS I: CATHODE RAY TUBES |
FEB 1954 |
|
| Authors:
JOHN H. MITCHELL; TUFTS UNIV MEDFORD MA
|
|
| GROUP BEHAVIOR STUDIES. II. RELATION OF SOCIOMETRIC CHOICES TO PERSONALITY PATTERNS |
FEB 1954 |
|
| Authors:
WILLIAM C. SCHUTZ; TUFTS UNIV MEDFORD MA
|
|
| SYMBOLIC CODING FOR THE SIMULATION OF SYSTEMS ON DIGITAL COMPUTERS |
DEC 1953 |
1 pages |
| Authors:
EARL J. ISAAC; TUFTS UNIV MEDFORD MA
|
|
| EXPERIMENTAL EVIDENCE FOR IMPROVEMENTS MEEDED IN RIFLE MARKSMANSHIPTRAINING |
15 JUN 1953 |
|
| Authors:
RICHARD S. HIRSCH; TUFTS UNIV MEDFORD MA
|
|
| The Legibility of Type As a Function of Reflectance of Background under Low Illumination |
JUN 1952 |
24 pages |
| Authors:
Mason N. Crook; John A. Hanson; JOSEPH W. WULFECK; TUFTS UNIV MEDFORD MA
|
| The legibility of lower case type as a function of illumination level, reflectance of background, and type size was measured by means of speed and accuracy scores on a letter cross out test. Simulated red cockpit illumination was used, covering the range from 0.014 to 0.129 foot-candles. Red light reflectance of background was varied from 0.26 to 0.87. Type sizes were 6 and 8 point. Scores fell off at an ... |
|
Reports by Corporate Author
