| Analytical and Characteristics Studies of Organic Chemicals, Drugs, and Drug Formulations |
Nov 2012 |
10 pages |
| Authors:
Peter Lim; SRI INTERNATIONAL MENLO PARK CA
|
 | During the period October 22, 2011 to October 21, 2012, the project personnel continued to perform chemical/physical analyses on bulk pharmaceutical substances and formulated drug products, and to develop dosage formulations of interest to the USAMRMC Drug Development Program for parasitic and infectious diseases, chemical and biological defense, etc. Specific objectives were to design, develop, validate, and apply methods to determine chemical and physical characteristics of the bulk drugs, drug ... |
|
| Spin-Precession Organic Magnetic Sensor |
26 Sep 2012 |
26 pages |
| Authors:
Srini Krishnamurthy; SRI INTERNATIONAL MENLO PARK CA
|
| SRI International, in collaboration with Professor Jing Shih of the University of California- Riverside (UCR), Professor Nathan Newman of Arizona State University (ASU), and Professor Edmond Nowak of the University of Delaware (UD), has been funded (from June 2009 through September 2012) through ONR Contract (N00014-09-C-0292) to fabricate a magnetic sensor with a half-metallic ferromagnet (FM) contact and polymers and demonstrate its sensing capability. In this study we considered La0.7Sr0..3MnO3 ... |
|
| Effect of a Hypocretin/Orexin Antagonist on Neurocognitive Performance |
Sep 2012 |
44 pages |
| Authors:
Thomas S Kilduff; SRI INTERNATIONAL MENLO PARK CA
|
| During Year 3, results continued to accumulate that are consistent with the hypothesis that disfacilitation of wake-promoting systems by the hypocretin (Hcrt) receptor antagonist almorexant (ALM) results in less functional impairment than the inhibition of neural activity produced by the benzodiazepine receptor agonist zolpidem (ZOL). Measures of both spatial reference memory (Task 2a) and spatial working memory (Task 2b) in rodents treated with ALM were mostly indistinguishable from vehicle whereas ... |
|
| Spin-Precession Organic Magnetic Sensor |
Jun 2012 |
10 pages |
| Authors:
Srini Krishnamurthy; SRI INTERNATIONAL MENLO PARK CA
|
| This report documents the results of CoFe50Al25Si25 (CFAS) studies carried out by SRI International in collaboration with Professor Nate Newman s group at Arizona State University (ASU) under ONR Contract N00014-09-C-0292. In this period we have: (1) grown and characterized both electrically and magnetically a new half-metal CFAS that has desirable properties for use at room temperature; (2) fabricated several nonlocal devices with CFAS and polymer for magnetic sensing; and ... |
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| Performance-Enhancing Materials for Future Generation Explosives and Propellants |
25 May 2012 |
26 pages |
| Authors:
Mark A Petrie; Gary Koolpe; Ripudaman Malhotra; Paul Penwell; SRI INTERNATIONAL MENLO PARK CA
|
| During this grant, SRI has made progress in areas of interest to Navy work thrusts, specifically ammonium perchlorate oxidizer replacement and candidates for insensitive munitions. N-oxidation of nitro-heterocycles can boost oxygen content and increase density of the parent material. Through this work, synthesis methodology for more difficult ring N-oxidation of a variety of nitroheterocycles has been expanded. SRI has explored the limits of N-oxidation using hypofluorous acid (HOF) and persulfate ... |
|
| MABLE Final Report |
30 Nov 2011 |
123 pages |
| Authors:
Michael Freed; SRI INTERNATIONAL MENLO PARK CA
|
| This is the final report describing research objectives, approach and results for work by SRI International and its subcontractors under the DARPA Bootstrapped Learning Program. |
|
| Analytical and Characterization Studies of Organic Chemicals, Drugs, and Drug Formulation |
21 Nov 2011 |
11 pages |
| Authors:
Peter Lim; SRI INTERNATIONAL MENLO PARK CA
|
| During the period October 22, 2010 to October 21, 2011, the project personnel continued to perform chemical/physical analyses on bulk pharmaceutical substances and formulated drug products, and to develop dosage formulations of interest to the USAMRMC Drug Development Program for parasitic and infectious diseases, chemical and biological defense, etc. Specific objectives were to design, develop, validate, and apply methods to determine chemical and physical characteristics of the bulk drugs, drug ... |
|
| Testing and Modeling Ultra-High Temperature Ceramic (UHTC) Materials for Hypersonic Flight |
Nov 2011 |
134 pages |
| Authors:
Jochen Marschall; SRI INTERNATIONAL MENLO PARK CA
|
| This project focused on zirconium diboride and hafnium diboride ultra-high temperature ceramics in two main research areas: i) their thermal and electrical transport properties; and ii) their oxidation and volatilization behavior in simulated re-entry environments. The first area involved experimental studies of the thermal and electrical properties as a function of temperature, and the analysis of these results in terms of effective conductivity and Wiedemann-Franz models. Thermal diffusivity was measured ... |
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| Principles and Foundations for Fractionated Networked Cyber-Physical Systems |
14 Oct 2011 |
5 pages |
| Authors:
Mark-Oliver Stehr; Patrick Lincoln; SRI INTERNATIONAL MENLO PARK CA
|
| We propose to explore a new paradigm for design of high-assurance Networked Cyber-Physical Systems based on the notion of software fractionation with distributed control and optimization aiming at the effective use of resources. The idea of software fractionation is inspired by and complementary to hardware fractionation, which has been proposed for mission-critical space systems. In our approach, software is fractionated by design even beyond the distributed nature of underlying system, ... |
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| META 2f: Probabilistic, Compositional, Multi-dimension Model-Based Verification (PROMISE) |
Oct 2011 |
127 pages |
| Authors:
Grit Denker; Linda Briesemeister; Daniel Elenius; Shalini Ghosh; Ian Mason; Ashish Tiwari; Devesh Bhatt; Haftay Hailu; Gabor Madl; Siamak Nikbin; Srivatsan Varadarajan; Guenther Bauer; Wilfried Steiner; Xenofon Koutsoukos; Tihamer Levendovszky; SRI INTERNATIONAL MENLO PARK CA
|
| Research efforts were conducted under this task order to emphasize unique technologies in support of achieving the program goals associated with the META Program. The contractor focused on technologies and technological breakthroughs addressing probabilistic verification of cyber physical system aspects. Collaboration with Honeywell International Inc.,Aerospace, TTTech Computertechnik AG, and Vanderbilt University was facilitated to optimize technology development. The contractor team developed various probabilistic verification tools for component and tools for ... |
|
| Effect of a Hypocretin/Orexin Antagonist on Neurocognitive Performance |
Sep 2011 |
20 pages |
| Authors:
Thomas S Kilduff; SRI INTERNATIONAL MENLO PARK CA
|
| During Year 2, a new laboratory for behavioral performance assessment and microdialysis sampling was occupied and two new HPLCs were purchased and calibrated. Both the benzodiazepine receptor agonist zolpidem (ZOL) and the hypocretin (Hcrt) receptor antagonist almorexant (ALM) induced sleep in rodents. However, ALM did not impair performance in a spatial reference memory test whereas ZOL did. Preliminary results indicate that the wake-active Hcrt neurons could be activated in the ... |
|
| Spin-Precession Organic Magnetic Sensor |
JUN 2011 |
12 pages |
| Authors:
Srini Krishnamurthy; SRI INTERNATIONAL MENLO PARK CA
|
| This report consists of two parts--results from La0.7Sr0..3MnO3 (LSMO) studies carried out in collaboration with the University of Delaware (UD) and the University of California at Riverside (UCR); and results from CoFe50Al25Si25 (CFAS) studies carried out in collaboration with Arizona State University (ASU)--both conducted under ONR Contract (N00014-09-C- 0292). The objective of the project is to develop an ultrasensitive magnetic sensor for room temperature operation. The requirements are (a) half-metallic ... |
|
| Power MEMS Development |
May 2011 |
47 pages |
| Authors:
Drew Hanser; SRI INTERNATIONAL MENLO PARK CA
|
| The objective of the research in this task was to demonstrate the feasibility of using microelectromechanical system (MEMS) switches as a circuit breaker for electric power management. The concept is to use electrostatically actuated MEMS cantilever switches with integrated bimorph structures to create vertical switches with the capacity to automatically interrupt current flow when over-current situations arise. Using electrostatic actuation, we will be able to reset the circuit breaker following ... |
|
| Power Mems Development |
Feb 2011 |
4 pages |
| Authors:
Drew Hanser; John Bumgarner; SRI INTERNATIONAL MENLO PARK CA
|
| In Task 1.1, we were able to fabricate two silicon-on-insulator (SOI) wafers and two double-side-polished (DSP) wafers. The fabricated wafers were bonded and then released and tested for circuit breaker configuration. The first bonded wafer pair failed during the deep reactive-ion etching (DRIE) release step due to insufficient masking material. This bonded wafer pair was processed in SRI's MicroSystems Engineering Laboratory in Menlo Park, CA (MSELWest), where the selectivity of ... |
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| The SRI NIST 2010 Speaker Recognition Evaluation System (PREPRINT) |
Jan 2011 |
5 pages |
| Authors:
Nicolas Scheffer; Luciana Ferrer; Martin Graciarena; Sachin Kajarekar; Elizabeth Shriberg; Andreas Stolcke; SRI INTERNATIONAL MENLO PARK CA
|
| The SRI speaker recognition system for the 2010 NIST speaker recognition evaluation (SRE) incorporates multiple subsystemswith a variety of features and modeling techniques. We describe our strategy for this year's evaluation, from the use of speech recognition and speech segmentation to the individual system descriptions as well as the final combination. Our results show that under most conditions, the cepstral systems tend to perform the best, but that other, non-cepstral ... |
|
| Power Mems Development |
31 DEC 2010 |
5 pages |
| Authors:
Andrew Hanser; John Bumgarner; SRI INTERNATIONAL MENLO PARK CA
|
| This month in Task 1.1, we processed wafers with the revised Metal 3 and Dielectric masks. We completed the processing of the double-side-polished (DSP) wafer; however, the silicon-on-insulator (SOI) wafer is on hold due to deep reactive ion etching (DRIE) processing issues. In Task 1.2, we processed wafers with the new pre-sputter metal deposition process. We diced chips from these wafers and released them using both using hydrogen fluoride (HF) ... |
|
| Power Mems Development |
30 Nov 2010 |
4 pages |
| Authors:
Andrew Hanser; John Bumgarner; SRI INTERNATIONAL MENLO PARK CA
|
| This month in Task 1.1 we made changes to two masks (Metal 3 and Dielectric) to improve the performance of the circuit breaker. Both double-side-polished (DSP) and silicon-on-insulator (SOI) wafers were processed using the revised masks. |
|
| Analytical and Characterization Studies of Organic Chemicals, Drugs, and Drug Formulation |
Nov 2010 |
9 pages |
| Authors:
Peter Lim; SRI INTERNATIONAL MENLO PARK CA
|
| During the period October 22, 2009 to October 21, 2010, the project personnel continued to perform chemical/physical analyses on bulk pharmaceutical substances and formulated drug products, and to manufacture dosage formulations of interest to the USAMRMC Drug Development Program for parasitic and infectious diseases, chemical and biological defense, etc. Specific objectives were to design, develop, validate, and apply methods to determine chemical and physical characteristics of the bulk drugs, drug ... |
|
| Effect of a Hypocretin/Orexin Antagonist on Neurocognitive Performance |
01 SEP 2010 |
28 pages |
| Authors:
Thomas S. Kilduff; SRI INTERNATIONAL MENLO PARK CA
|
| During Year 1, progress was made on establishment of the infrastructure and baseline parameters to facilitate the proposed studies. Construction was initiated on a 535 s.f. lab suite within the Animal Facility that will provide an optimal environment for execution of the proposed in vivo studies; we expect to occupy this laboratory next week. An Analytical Neurochemistry Facility was established in LB212 and 4 HPLCs were purchased, installed, calibrated and ... |
|
| Formation of Defect Microstructures and Electrical Transport in VOx |
30 Jun 2010 |
39 pages |
| Authors:
Zhi G Yu; SRI INTERNATIONAL MENLO PARK CA
|
| This report summarizes SRI's accomplishments from 07/01/05 to 06/30/10 on the, Formation of Defect Microstructures and Electrical Transport in VOx project. We have successfully carried out all tasks identified in our initial proposal and supplements and gained significant knowledge and understanding of electrical transport, optical properties, and electronic structures in vanadium oxide (VOx), the most favored material for uncooled microbolometers, and in related highly disordered systems. We have developed algorithms ... |
|
| Principles and Foundations for Fractionated Networked Cyber-Physical Systems |
14 Jun 2010 |
5 pages |
| Authors:
Mark-Oliver Stehr; Patrick Lincoln; SRI INTERNATIONAL MENLO PARK CA
|
| A new generation of mission-critical systems is emerging that employs distributed, dynamically reconfigurable open architectures. These systems may include a variety of devices that sense and affect their environment and the configuration of the system itself. We call such systems Networked Cyber- Physical Systems (NCPS). NCPS can provide complex, situation-aware, and often critical services in applications such as distributed sensing and surveillance, crisis response, self-assembling structures or systems, networked satellite ... |
|
| AUV-12 Sonar Integration and Evaluation |
26 Feb 2010 |
11 pages |
| Authors:
John Kloske; SRI INTERNATIONAL MENLO PARK CA
|
| The primary goal of Contract N00014-09-C-0301 is to integrate the CodaOctopus EchoScope MKII (ES MKII) high-resolution, volumetric three-dimensional (3D) sonar system into a Bluefin Robotics B12 autonomous underwater vehicle (AUV) payload. Previously, SRI International (SRI) built and tested an AUV payload consisting of the BlueView Technologies 3DSLS, a multibeam sonar that, when fused with the navigation data, can generate highly detailed 3D mosaics. As part of the current effort, we ... |
|
| Analytical and Characterization Studies of Organic Chemicals, Drugs, and Drug Formulations for Walter Reed Army Institute of Research, Silver Spring, MD |
Nov 2009 |
11 pages |
| Authors:
Peter Lim; SRI INTERNATIONAL MENLO PARK CA
|
| During the period October 22, 2008 to October 21, 2009, the project personnel continued to perform chemical/physical analyses on bulk pharmaceutical substances and formulated drug products, and to manufacture dosage formulations of interest to the USAMRMC Drug Development Program for parasitic and infectious diseases, chemical and biological defense, etc. Specific objectives were to design, develop, validate, and apply methods to determine chemical and physical characteristics of the bulk drugs, drug ... |
|
| Political, Military, Economic, Social, Infrastructure, Information (PMESII) Effects Forecasting for Course of Action (COA) Evaluation |
Jun-2009 |
57 pages |
| Authors:
John D Lawrence; Janet L Murdock; SRI INTERNATIONAL MENLO PARK CA
|
| Comprehensive effects-based planning requires that diplomatic, information, military, and economic (DIME) options be considered, along with their potential impacts on the political, military, economic, social, infrastructure, and information (PMESII) environment. Given that the cause-effect relationships among these are not well understood, modeling these relationships and using them to forecast plausible outcomes is a challenging technical problem. This effort developed a Probative Rapid Interactive Modeling Environment (PRIME) software tool for effects ... |
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| Information Integration Seedling for Data Integration and exploitation System that Learns (DIESEL) |
Apr-2009 |
25 pages |
| Authors:
Pedro M Domingos; SRI INTERNATIONAL MENLO PARK CA
|
| The goal of the University of Washington effort under DIESEL is to develop a unified approach to entity, schema and concept matching. Entity resolution is the problem of determining which mentions in the data correspond to the same object (e.g., J. Smith and Jane Smith may be the same person). Schema matching is the problem of determining which fields in a database or other structure correspond to the same attributes ... |
|
| Analytical and Characterization Studies of Organic Chemicals, Drugs, and Drug Formulation |
Mar-2009 |
13 pages |
| Authors:
Peter Lim; SRI INTERNATIONAL MENLO PARK CA
|
| Although the overall purpose of this contract was to perform chemical/physical analyses on bulk pharmaceutical substances and formulated drug products of interest to the USAMRMC Drug Development Program for parasitic and infectious diseases, chemical and biological defense, etc, by far the majority of time and effort expended during the current contract was devoted to design, development, and cGMP manufacture of an artesunic acid parenteral dosage form. Over 5,000 units of ... |
|
| Development and Deployment of In Situ Mass Spectrometers |
07 Jan 2009 |
9 pages |
| Authors:
R T Short; Strawn K Toler; SRI INTERNATIONAL MENLO PARK CA
|
| The objectives for this project were diverse, including underwater mass spectrometer (MS) deployments focusing on quantitative measurements of dissolved gases, and improvements on existing 200-amu systems and peripherals. Plume mapping capabilities were to be extended by integrating the underwater MS with a remotely operated vehicle (ROV), and by exploring methods to mathematically improve the spatial and temporal resolution of membrane introduction MS measurements. Instrumental developments (e.g., a novel, modular, deep-water ... |
|
| Estimation of Temporally Evolving Typhoon Winds and Waves from Synthetic Aperture Radar |
Jan 2009 |
6 pages |
| Authors:
David T Walker; SRI INTERNATIONAL MENLO PARK CA
|
| The long-term goal of this project is to develop a methodology for using synthetic aperture radar (SAR) data to improve characterization of the winds and waves generated by typhoons in the western Pacific Ocean. The specific objective of the project is to develop a variational assimilation algorithm based on the SWAN model to estimate the near-surface typhoon wind field from SAR data. Third-generation wave spectrum models such as SWAN can ... |
|
| Testing and Evaluation of the Mobile Inspection Package |
01-Oct-2008 |
11 pages |
| Authors:
John Kloske; SRI INTERNATIONAL MENLO PARK CA
|
| The goal of this contract (N00014-07-C-0722) is to develop a portable system for underwater port security focusing on ship hull scanning. This, and previous efforts, have been to develop a system that meets the requirements of the Coast Guard, the Navy Explosive Ordnance Disposal Team (EOD) and local law enforcement. The result is a Mobile Inspection Package (MIP), capable of surveying ship hulls, seawall, pilings, and seafloors. The MIP can ... |
|
| ALASKA: Applet and Library Augmented Shared Knowledge Areas (Shared Workspace Project or Shared Spaces with Agents and Actors) |
20-May-2008 |
21 pages |
| Authors:
Eric Hamilton; Phil Vahey; SRI INTERNATIONAL MENLO PARK CA
|
| SRI completed the following tasks during this project: 1. A user test on a preliminary version of the ALASKA software. 2. A series of user tests conducted at SRI with pre-calculus students from a local community college. 3. Contributed to the technological capabilities of the ALASKA system. 4. Created designs for potential implementations of ALASKA representations. 5. Advised on, and helping to organize, a set of AgileViz workshops conducted at ... |
|
| Spin-Precession Organic Magnetic Sensor |
11-Apr-2008 |
43 pages |
| Authors:
Srini Krishnamurthy; SRI INTERNATIONAL MENLO PARK CA
|
| The three major tasks we addressed in this project were to: (a) identify the issues for demonstration of a polymer-based spin-precession magnetic sensor; (b) develop theoretical and computational techniques to study the effect of the interface between ferromagnetic metal and polymers for FET applications; and (c) apply the existing light propagation codes to study transmission of 1.5 micron wavelength light through GaAs. We have completed all three tasks, and the ... |
|
| Disruptive Civil Technologies: Six Technologies With Potential Impacts on US Interests Out to 2025 |
Apr 2008 |
47 pages |
| Authors:
SRI INTERNATIONAL MENLO PARK CA
|
| To support the development of the National Intelligence Council's Global Trends 2025, SRI Consulting Business Intelligence (SRIC-BI) was asked to identify six potentially disruptive civil or dual use technologies that could emerge in the coming fifteen years (2025). A disruptive technology is defined as a technology with the potential to causes a noticeable - even if temporary - degradation or enhancement in one of the elements of US national power ... |
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| Prime: A PMESII (Political, Military, Economic, Social, Infrastructural and Informational) Model Development Environment |
JAN 2008 |
49 pages |
| Authors:
Ian Harrison; SRI INTERNATIONAL MENLO PARK CA
|
| As a key component of effects-based operations (EBO) is to allow analysts to examine the effects that different courses of action would have on a situation from multiple viewpoints, PRIME is a software tool for political, military, economic, social, infrastructural, and informational (PMESII) modeling that supports this need by looking beyond the traditional narrow horizon of examining only the military effects of planned actions. PRIME supports modeling of military actions, ... |
|
| Accurate Evaluation of Nonlinear Absorption Coefficients in InAs, InSb and HbCdTe Alloys (Postprint) |
06 JUN 2007 |
15 pages |
| Authors:
Shekhar Guha; Zhi G. Yu; SRINIVASAN KRISHNAMURTHY; Leonel P. Gonzales; SRI INTERNATIONAL MENLO PARK CA
|
| We present a full band structure calculation of temperature- and wavelength-dependent two-photon absorption (TPA) coefficients and free carrier absorption (FCA) cross sections in InAs, InSb, and Hg1−xCdxTe alloys. Although the wavelength dependence of the TPA coefficients agrees well with Wherrett expression, the accurately calculated values are smaller by a factor of 1.2 to 2.5. In addition, the TPA coefficient depends sensitively on the photoexcited carrier density in small gap material. ... |
|
| A Problem-Solving Environment for Biological Network Informatics: Bio-Spice |
JUN 2007 |
142 pages |
| Authors:
Patrick Lincoln; Charles J. Pedersen; SRI INTERNATIONAL MENLO PARK CA
|
| The integration of multiple bioinformatics tools into an integrated suite poses many software engineering, social, and research challenges. We present our work on Bio-SPICE, an integrated open-source framework of tools for modern biology. SRI led the integration tasks, bringing together a community of researchers and practitioners to agree on a set of standards and practices that enabled multiple tools from multiple institutions to be brought to bear on problems of ... |
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| Photoexcited-Carrier-Induced Refractive Index Change in Small Bandgap Semiconductors (POSTPRINT) |
NOV 2006 |
8 pages |
| Authors:
Z. G. Yu; Srini Krishnamurthy; Shekhar Guha; SRI INTERNATIONAL MENLO PARK CA
|
| Using accurate band structures of InAs, InSb, and two Hg(1-x)CdxTe alloys, we calculate the change in refractive index caused by the photoexcited electrons and holes. The effects of both free-carrier absorption (FCA) and one-photon absorption are considered. We find that the change in refractive index varies nonlinearly with the density of photoexcited carriers and that the generally neglected FCA contribution is significant in InAs, owing to its weak spin-orbit coupling. ... |
|
| Analytical and Characterization Studies of Organic Chemicals, Drugs and Drug Formulations |
OCT 2006 |
10 pages |
| Authors:
Peter Lim; SRI INTERNATIONAL MENLO PARK CA
|
| During the annual contract period, September22, 2005 to September21, 2006, the project personnel continued to perform chemical/physical analyses on bulk pharmaceutical substances and formulated drug products, and to develop and (with borrowed labor) manufacture dosage formulations of interest to the USAMRMC Drug Development Program for parasitic and infectious diseases, chemical and biological defense, etc. Specific objectives were to design, develop, validate, and apply methods to determine chemical and physical characteristics ... |
|
| Low Temperature, Low Pressure Fabrication of Ultra High Temperature Ceramics (UHTCs) |
AUG 2006 |
116 pages |
| Authors:
Yigal Blum; Jochen Marschall; Hans J. Kleebe; SRI INTERNATIONAL MENLO PARK CA
|
| The US Air Force is interested in developing fiber-reinforced ceramic composites that perform at ultra-high temperatures (greater or more than 1500 degrees C) under oxidative conditions, especially for hypersonic vehicles. Two potential approaches are: (a) Utilizing existing carbon-fiber-reinforced carbon-matrix composites (C/C) or carbon-fiber-reinforced silicon carbide-matrix composites (C/SiC) coated by thick (>100 um) ultra-high temperature ceramic (UHTC) coatings, or (b) Replacing the C and SiC matrices of such composites with an ... |
|
| Matter: Modular Adaptive Technology Targeting Efficient Reasoning |
JUL 2006 |
65 pages |
| Authors:
Tomas Uribe; Charles Lieber; SRI INTERNATIONAL MENLO PARK CA
|
| The objective of this effort was to investigate novel computer architectures to support machine learning, based on reconfigurable hardware and nanowire growth. The scope of this effort was to bring revolutionary architectural ideas together with application drivers that embody cognitive processing dimensions such as machine learning, large knowledge bases, information security and integrity, real-world reasoning, sensor integration and real time embedded systems. Conventional processing architectures are ill-suited to processing the ... |
|
| Reading to Learn |
30 JUN 2006 |
34 pages |
| Authors:
David J. Israel; Peter E. Clark; Phil Harrison; John Thompson; Rick Wojcik; Tom Jenkins; SRI INTERNATIONAL MENLO PARK CA
|
| One of the most important methods by which human beings learn is by reading, a task that includes integrating what was read with existing, prior knowledge. While in its full generality, the reading task is still too difficult a capability to be implemented in a computer, significant (if partial) approaches to the task are now feasible. Our goal in this project was to study issues and develop solutions for this ... |
|
| High Intensity Light Propagation In InAs (Postprint) |
JUN 2006 |
6 pages |
| Authors:
Shekhar Guha; Leo Gonzalez; SRI INTERNATIONAL MENLO PARK CA
|
| We present our experimental and theoretical results on nonlinear absorption of light in InAs. The nonlinear variation of output intensity as a function of input intensity and time are calculated by solving four coupled rate equations simultaneously. All required quantities, including two-photon absorption, free-carrier absorption, Auger and radiative recombination lifetimes, and intrinsic carrier densities, have been obtained from the underlying bandstructures. The calculated thickness and energy-dependent output intensities in InAs ... |
|
| Luminaires |
MAY 2006 |
71 pages |
| Authors:
Eric Arons; SRI INTERNATIONAL MENLO PARK CA
|
| The goal of the HEDLight program is to develop a complete remote source lighting system for area, task, and navigational lighting on naval platforms. Within the scope of the overall program is the development of the source, distribution system, and luminaire, along with the integration of the entire system. The technical objectives of the program emphasize the attainment of high efficiency with regard to electrical, mass, and luminous output. In ... |
|
| Enhancement of an Analytical Method for the Determination of Squalene in Anthrax Vaccine Absorbed Formulations |
20 Apr 2006 |
7 pages |
| Authors:
Ronald J Spanggord; Meg Sun; Peter Lim; William Y Ellis; SRI INTERNATIONAL MENLO PARK CA
|
| Specific lots of anthrax vaccine adsorbed administered to members of the U.S. Armed Forces have been alleged to contain squalene, a chemical purported to be associated with illnesses of Gulf War veterans. A method of enhanced sensitivity for determining squalene in anthrax vaccine adsorbed using high-performance liquid chromatography with photodiode array detection has been developed, validated, and applied to 44 bottles of 38 lots of anthrax vaccine. In 43 bottles ... |
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| Low Temperature Reactivities of Ultra-High Temperature Ceramics (Hf-X System) |
MAR 2006 |
11 pages |
| Authors:
Yigal Blum; SRI INTERNATIONAL MENLO PARK CA
|
| A growing interest in ultra-high temperature ceramics and their aerospace and turbine applications has led to a renewal of activities to fabricate MB2/SiC composites as the materials of choice, because of their high thermal and oxidation resistance stability. Unfortunately, these composites are currently formed by an expensive, size and shape limited hot-press operation at a temperature range of 1900 to 2200 degrees C. The project investigated chemical reactions at and ... |
|
| Knowledge Creation Tools for DAML |
MAR 2006 |
26 pages |
| Authors:
David L. Martin; Grit Denker; Richard Waldinger; Jerry Hobbs; SRI INTERNATIONAL MENLO PARK CA
|
| This report summarizes the work done by SRI International for DARPA's DAML research program during the period 2000-2005. This work falls into six categories. Using a first-order logic theorem prover, we verified and refined the axiomatic semantics of DAML+OIL and OWL. We led collaborative efforts to develop foundation ontologies of time and space for the Semantic Web. We led collaborative efforts to develop ontologies and related technologies for describing and ... |
|
| "Low"-Temperature Reactivities of Ultra-High Temperature Ceramics (Hf-X System) |
DEC 2005 |
11 pages |
| Authors:
Yigal Blum; Marc Hornbostel; D. B. MacQueen; David Hui; Steve Young; Jochen Marschall; Esperanza Alvarez; Hans-Joachim Kleebe; SRI INTERNATIONAL MENLO PARK CA
|
| A growing interest in ultra high temperature ceramics and their aerospace and turbine applications has led to a renewal of activities to fabricate MB2/SiC composites as the materials of choice, because of their high thermal and oxidation resistance stability. Unfortunately, these composites are currently formed by an expensive, size and shape limited hot-press operation at a temperature range of 1900 to 2200 C. The project investigated chemical reactions at and ... |
|
| Ultrascalable Techniques Applied to the Global Intelligence Community Information Awareness Common Operating Picture (IA COP) |
NOV 2005 |
50 pages |
| Authors:
Alfonso Valdes; Jim Kadte; SRI INTERNATIONAL MENLO PARK CA
|
| The focus of this research is to develop detection, correlation, and representation approaches to address the needs of the Intelligence Community Information Awareness Common Operating Picture (IA COP). The approaches build on existing enterprise information security tools where appropriate, and depart from these traditional methods where required. In particular, the requirement to scale to large networks and data repositories is the primary driver for technical innovation. We explored the following ... |
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| Power Composites: Structural Materials that Generate and Store Electrical Energy |
31 OCT 2005 |
44 pages |
| Authors:
Donald A. Shockey; Susanna C. Ventura; Subhash C. Narang; Jeffrey W. Simons; Benjamin C. Bourne; Brian D. Peterson; SRI INTERNATIONAL MENLO PARK CA
|
| We describe progress in the development of a synthetic multifunctional material: namely a fiber composite with both power and structural function. The structural composite contains batteries encased in piezoelectric tubes. When the structure vibrates the tubes generate electricity that is stored in the batteries; thus the composite material provides a long-term and stable self-recharging source of power that can be used, for example, to drive electronics. We also developed an ... |
|
| Analytical and Characterization Studies of Organic Chemicals, Drugs and Drug Formulations |
OCT 2005 |
11 pages |
| Authors:
Peter Lim; SRI INTERNATIONAL MENLO PARK CA
|
| During the annual contract period, September 22, 2004 to September 21, 2005, the project personnel continued to perform chemical/physical analyses on bulk pharmaceutical substances and formulated drug products, and to develop and (with borrowed labor) manufacture dosage formulations of interest to the USAMRMC Drug Development Program for parasitic and infectious diseases, chemical and biological defense, etc. Specific objectives were to design, develop, validate, and apply methods to determine chemical and ... |
|
| Breast Cancer Detection Using Optical Vascular Fusion |
JUN 2005 |
52 pages |
| Authors:
Gregory W. Faris; SRI INTERNATIONAL MENLO PARK CA
|
| We are investigating a new approach to detection of breast cancer using optical vascular function imaging. Research on cancer therapy has revealed unusual properties of tumor vasculature produced through angiogenesis that have high promise for breast cancer detection. We are using this unusual behavior as a contrast mechanism by performing optical imaging during administration of different levels of oxygen and carbon dioxide. We have constructed imaging systems using immersion in ... |
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Reports by Corporate Author
