| Wave Propagation in Layered Cylindrical Structures Using Finite Element and Wave Tracing Analysis |
May 2010 |
17 pages |
| Authors:
Sachiko Sueki; Samaan G Ladkany; Brendan J O'Toole; NEVADA UNIV LAS VEGAS
|
 | In this study, acceleration responses of layered cylindrical structures are obtained using finite element analysis (FEA) and wave tracing technique. The wave tracing technique implies a direct application of the wave propagation equation which includes propagating wave and its reflections at the interfaces due to effect of impedance differences in layered structure. Wave tracing clearly supported FEA results which had showed that interference between applied impact and reflected waves affects ... |
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| Heat Shock Protein 27 Inhibits Apoptosis by Binding Cytochrome c |
JUN 2003 |
131 pages |
| Authors:
Stephen W. Carper; NEVADA UNIV LAS VEGAS
|
| The purpose of this research project is to investigate the interaction between heat shock protein 27 (hsp27) and cytochrome c in the inhibition of apoptosis. The scope of the study was to include: measuring the binding of hsp27 to cytochrome c in vivo, determining why hsp27 binds to cytochrome c and determining the fate of the hsp27:cytochrome c complex. Major findings include cellular survival curves to cytochrome C, ATP, FAD ... |
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| Analysis of Two Methods of Isometric Muscle Contractions During the Anti-G Straining Maneuver |
MAY 2003 |
85 pages |
| Authors:
Lance L. Annicelli; NEVADA UNIV LAS VEGAS
|
| This study investigated the difference in Mean Arterial Pressure (MAP) and Cardiac Output (CO) between two methods of isometric muscle contractions during the Anti-G Straining Maneuver (AGSM). 12 subjects (ages 18 to 38 years, height 176.8 plus or minus 7.4 cm, body mass 78.8 plus or minus 15. 6 kg, percent body fat 14.3 plus or minus 6.6%) participated in the study. The study was a one-way within-subject design with ... |
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| Cell Migration as a Therapeutic Target in Malignant Breast Cancer |
SEP 2002 |
141 pages |
| Authors:
George E. Plopper Jr.; NEVADA UNIV LAS VEGAS
|
| The objects of this project are to develop a high-throughput method for screening potential inhibitors of breast cancer cell migration, and to apply this method to identify signaling events mediating constitutive migration of malignant breast cells. The pathways that control these signaling events may be targets for development of new classes of anti-tumor drugs. The significant advances made during this project include (1) development of an efficient, high- throughput migration ... |
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| Heat Shock Protein 27 Inhibits Apoptosis by Binding Cytochrome C |
JUN 2002 |
5 pages |
| Authors:
Stephen W. Carper; NEVADA UNIV LAS VEGAS
|
| The purpose of this research project is to investigate the interaction between heat shock protein 27 (hsp27) and cytochrome c in the inhibition of apoptosis. The scope of the study will include: measuring the binding of hsp27to cytochrome c in vivo, determining why hsp27 binds to cytochrome c and determining the fate of the hsp27:cytochrome c complex. Major findings to date include: cellular survival cures to cytochrome c and molecular ... |
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| Elucidation of Pertussis Toxin-Sensitive Migration Signaling in Human Breast Cancer Cells |
MAY 2002 |
45 pages |
| Authors:
William L. Rust; NEVADA UNIV LAS VEGAS
|
| The long range goal of this laboratory is to identify integrin- associated signaling events that contribute to the constitutive migration of human breast cancer cells on the laminin extracellular matrix proteins. This project has shown that the heterotrimeric G-protein Galphai3 may link integrin activation and migration of MCF-lOA cells via a cAMP signaling pathway. The focus of the remaining work on this project is to identify how each integrin subtype ... |
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| The Relationship Between Employee Personality Traits and Preferred Leadership Style |
14 JAN 2002 |
94 pages |
| Authors:
Thomas M. Kuhn Jr.; NEVADA UNIV LAS VEGAS
|
| The purpose of this study is to examine how employee personality traits are related to a preferred leadership style and how the differences between preferred and actual leadership style relate to employee perceptions of leader satisfaction and effectiveness. Respondents completed a survey questionnaire that consisted of the commonly used Multi-Factor Leadership Questionnaire Form 5X to assess employee leadership preferences and the NEO-FFI to identify personality traits. The relationship between employee ... |
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| Cell Migration as a Therapeutic Target in Malignant Breast Cancer |
SEP 2001 |
28 pages |
| Authors:
George E. Flopper Jr; NEVADA UNIV LAS VEGAS
|
| The object of this project is to develop a high-throughput method for screening potential inhibitors of breast cancer cell haptotaxis and chemotaxis, and to apply this method to identify signaling events mediating constitutive migration of malignant breast cells. The pathways that control these signaling events may be targets for development of new classes of anti-tumor drugs. The significant advances made during the third year of the project include generation of ... |
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| The Role of Focal Adhesion Kinase and CAS in Integrin-Mediated Signaling on Distinct Forms of Laminin-5 |
JUL 2001 |
6 pages |
| Authors:
Janice L. Huff; NEVADA UNIV LAS VEGAS
|
| Breast cancer develops in two stages The first, hyperproliferation, causes primary tumors and is rarely lethal. In the second stage, malignancy, tumor cells penetrate the surrounding basement membrane layer of extracellular matrix proteins and migrate into adjacent tissues where they form secondary, metastatic tumors. The defining characteristics of malignant cancer cells are hyperproliferation and an aggressively migratory phenotype. We have two models whereby an immortal, non-metastatic breast epithelial cell can ... |
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| Application of Resonant Ultrasound Spectroscopy to Determine the Elastic Properties of Macroscopic Rock Samples |
04 JUN 2001 |
11 pages |
| Authors:
K. R. McCall; T. J. Ulrich; P. A. Johnson; T. W. Darling; A. Migliori; NEVADA UNIV LAS VEGAS
|
| Resonant Ultrasound Spectroscopy (RUS) is a method whereby the elastic tensor of a sample is extracted from measured resonance frequencies. Typically, a rectangular parallelepiped sample is placed between two piezoelectric transducers, a source and a detector. The sample is driven at constant voltage as the frequency is swept through multiple resonances. The measured resonance frequencies are the input to an iterative inversion algorithm that finds the best match between the ... |
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| Elucidation of Pertussis Toxin-Sensitive Migration Signaling in Human Breast Cancer Cells |
MAY 2001 |
15 pages |
| Authors:
William L. Rust; NEVADA UNIV LAS VEGAS
|
| The long range goal of this laboratory is to identify integrin- associated signaling events that contribute to the constitutive migration of human breast cancer cells on the laminin extracellular matrix proteins. This project has shown that the heterotrimeric G-protein G alpha i3 may link integrin activation and migration of MCF-10A cells via a cAMP signaling pathway. The focus of the remaining work on this project is to identify how each ... |
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| Cell Migration as a Therapeutic Target in Malignant Breast Cancer |
SEP 2000 |
69 pages |
| Authors:
George E. Plopper Jr; NEVADA UNIV LAS VEGAS
|
| The object of this project is to develop a high-throughput method for screening potential inhibitors of breast cancer cell haptotaxis and chemotaxis, and to apply this method to identify signaling events mediating constitutive migration of malignant breast cells. The pathways that control these signaling events may be targets for development of new classes of anti-tumor drugs. The significant advances made during the second year of the project include the identification ... |
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| Cell Migration as a Therapeutic Target in Malignant Breast Cancer |
SEP 1999 |
20 pages |
| Authors:
George E. Plopper; NEVADA UNIV LAS VEGAS
|
| The object of this project is to develop a high-throughput method for screening potential inhibitors of breast cancer cell haptotaxis and chemotaxis, and to apply this method to identify signaling events mediating constitutive migration of malignant breast cells. The pathways that control these signaling events may be targets for development of new classes of anti-tumor drugs. The significant advances made during the first year of this project include: design and ... |
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| Research in Lightweight Elastic Robotic Arms |
10 JUN 93 |
23 pages |
| Authors:
T. A. Nartker; NEVADA UNIV LAS VEGAS
|
| The program involved a series of individual projects coordinated to develop controls for a flexible light weight robot arm. A hydraulically actuated 3-link robot arm was installed on a PRAB hydraulic base, and was designed of tubular steel. A PERT program chart was prepared (appendix B) on which various interrelated project milestones were projected. Robot design, Robotics, Robotic arms, Elastic robotic arm. |
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| The Dynamic Response of a Flexible Three-Link Robot Using Strain Gages and Lagrange Polynomials |
91 |
22 pages |
| Authors:
Samaan G. Ladkany; NEVADA UNIV LAS VEGAS
|
| A method for modeling elastic robot kinematics is presented in this paper. The method uses the input of strain gages and joint encoders to determine the deflection of the links in in-plane and out-of-plane directions. Torsional flexures also are measured using strain rosettes. This information determines the end effector location which can be then used by the robot controller to damp the robot vibrations. |
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| Minimum Covers for Grids and Orthogonal Polygons by Periscope Guards |
JUN 90 |
37 pages |
| Authors:
Laxmi Gewali; Simeon Ntafos; NEVADA UNIV LAS VEGAS
|
| The problem of finding minimum guard covers in NP-hard for simple polygons and open for simple orthogonal polygons. Alternative definitions of visibility have been considered for orthogonal polygons. In this paper we try to determine the complexity of finding guard covers in orthogonal polygons by considering periscope visibility. Under periscope visibility two points in an orthogonal polygon are visible if there is an orthogonal path with at most one bend ... |
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| External Watchman Routes |
90 |
29 pages |
| Authors:
Simeon Ntafos; Laxmi P. Gewali; NEVADA UNIV LAS VEGAS
|
| We consider the problem of finding a shortest watchman route from which the exterior of a polygon is visible (external watchman route). We present an O(n to the 4th power loglogn) algorithm to find shortest external watchman routes for simple polygons by transforming the external watchman route problem to a set of internal watchman route problems. Also, we present faster external watchman route algorithms for special cases. These include optimal ... |
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| Dynamic Simulation of a Three Degrees of Freedom Hydraulically Activated Robotic Arm with Flexible Links |
MAY 89 |
|
| Authors:
Mohamed B. Trabia; Woosoon Yim; NEVADA UNIV LAS VEGAS
|
 | The formulation of dynamic equations of motion of a three degrees of freedom hydraulically activated robotic arm with flexible links is presented. The dynamic model is based on Bernoulli-Euler theory for beams. It was found that the assumed modes method presents a suitable way of approximation to represent the system. The model is a set of nonlinear coupled ordinary differential equations. These equations solve the inverse dynamic problem by determining ... |
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| Fort Irwin Historic Preservation Plan. Volume 2. The Research Overview |
APR 86 |
|
| Authors:
Claude N. Warren; Margaret M. Lyneis; Michael S. Kelly; F. W. Bachhuber; NEVADA UNIV LAS VEGAS
|
| Chapter I presents a review of the available literature for Mojave Desert regional prehistory and identifies six chronological prehistoric cultural periods. In Chapter II, the research perspectives are identified and the Subsistence Focus Model is presented. Chapter III, bridges the gap between the archeological theories and hypotheses and the actual resources present on Fort Irwin. The historic resources of Fort Irwin are briefly examined in Chapter IV. Although extensive significant ... |
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| Modeling and Reduction of Shocks on Electronic Components Within a Projectile |
|
24 pages |
| Authors:
NEVADA UNIV LAS VEGAS
|
| Electronic components within a projectile are subjected to severe loads over an extremely short duration during the launch process. Failure of these components during launch can result in negative effects on the mission of the projectile. While experimental data can be helpful in understanding failure of electronic components within a projectile, collecting such data are [sic] usually difficult. There are also limitations on the reliability of sensors under these circumstances. ... |
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