Breast cancer is the leading diagnosed cancer in Asian American women. American women are more likely to receive a diagnosis in the advanced stages of the disease, primarily because of late detection. Understanding the cultural barriers to receipt of breast cancer screening (BCS) by Asian women and developing culturally appropriate programs to promote their use of BCS has become an urgent need in southeastern Michigan, where the Asian population has ...
Tumor biology is a recognized determinant of tumor behavior, including growth rate, motility and metastatic potential, and therapeutic resistance. This project was funded to investigate the regulation and expression of an excellent marker for aggressive breast tumors: RhoC-GTPase. When overactive, RhoC transforms mammary epithelial cells into a highly motile and invasive phenotype. We hypothesize that RhoC overexpression may be regulated by the transcription factor NF-kappa B and that at the ...
Reports by Corporate Author
