| DoD CPB-ECMO Initiative - A Suspended Animation Front Lines Casualty Management System |
DEC 2004 |
3 pages |
| Authors:
Fernando Casas; Andrew Reeves; David Dudzinski; Stephen Weber; Markus Lorenz; Martin Sinkewich; Robert Foster; William A. Smith; LERNER RESEARCH INST CLEVELAND CLINIC FOUNDATION OH
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 | Cardiopulmonary bypass (CPB), the shunting of blood around the heart and lungs, is a well-established technique that permits difficult surgical procedures on the heart and its adjacent main blood vessels. Extracorporeal membrane oxygenation (ECMO) uses similar equipment, with the primary goal of temporary pulmonary support by increasing the oxygen content and decreasing the carbon dioxide content of the blood, without the intent of performing open chest surgery. It, too, is ... |
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| Enzymatic Wound Disinfectants |
SEP 2002 |
12 pages |
| Authors:
Stanley L. Hazen; LERNER RESEARCH INST CLEVELAND CLINIC FOUNDATION OH
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| Wound infection and tissue damage are common and sever complications of injuries and burns sustained in baffle. The surgical excision of dead and devitalized tissue, antibiotics, and the removal of foreign matter are the mainstay of current therapies. Prevailing treatment strategies are restricted, however, by the inability to initiate effective countermeasures until removal from the uncontrolled environment of the field of battle. This results in high rates of infections and ... |
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| Development of a Biologic Basis for PSMA Targeting in Prostate Cancer |
FEB 2001 |
39 pages |
| Authors:
Warren D. Heston; LERNER RESEARCH INST CLEVELAND CLINIC FOUNDATION OH
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| We are going to define the biology of PSMA in order to enhance our ability to use PSMA as a target and to generate anti-tumor agents that will be specific and selective for PSMA protein. There is a PSMA-like protein that is similar to PSMA. We will identify that protein so we can develop agents that will be selective for the prostate PSMA protein. We want to know whether the ... |
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