| Simulation Learning: PC-Screen Based (PCSB) versus High Fidelity Simulation (HFS) |
Aug 2012 |
57 pages |
| Authors:
Kristine Qureshi; Denise Hopkins-Chadwick; HAWAII UNIV HONOLULU
|
 | The purpose of this project is to develop and test a model that can be used to compare different types of simulation learning for military and civilian nursing trauma skills. The model will enable measurement and comparison of changes in knowledge, skills and attitudes of the learner, as well as overall cost effectiveness for each type of simulation (PC screen based vs. high fidelity simulation). The final model will be ... |
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| Analysis of the Therapeutic Potential of Stem Cells to Facilitate Recovery from Cardiac Disease and Damage |
Jul 2012 |
13 pages |
| Authors:
Rich Allsopp; HAWAII UNIV HONOLULU
|
| Heart disease is the leading cause of death in both the United States and Hawaii, including men and women of the Armed Forces. Furthermore, chest trauma in military men and women can lead to cardiac injury and cardiomyopathy. There is presently no good therapy for injured myocardium. Stem cells hold great promise in the field of regenerative medicine, and may be the key to developing new therapies to treat cardiac ... |
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| Miniaturized Retrodirective Arrays for a Nanosatellite Platform |
01 Jan 2012 |
23 pages |
| Authors:
Wayne A Shiroma; Reece T Iwami; Wade G Tonaki; HAWAII UNIV HONOLULU
|
| A retrodirective antenna array (RDA) is capable of autonomously steering its radiation pattern toward the source of an interrogating signal, without having prior knowledge of the interrogator location. Integrating an RDA into a mobile platform, such as a nanosatellite, presents unique challenges due to the platform's restrictions in terms of size, weight, and power limitations. This project focused on developing novel RDA architectures that are directly suited for this resource-constrained ... |
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| Ho' oponopono: A Radar Calibration CubeSat |
13 Oct 2011 |
17 pages |
| Authors:
Wayne A Shiroma; Larry K Martin; Nicholas G Fisher; Windell H Jones; John G Furumo; Jr Ah Heong James R; Monica M Umeda; HAWAII UNIV HONOLULU
|
| To accurately identify and track objects over its territories, the US military must regularly monitor and calibrate its 80+ C-band radar tracking stations distributed around the world. Unfortunately, only two calibration satellites are currently in service, and both have been operating well past their operational lifetimes. Losing either satellite will result in a community of users that no longer has a reliable means of radar performance monitoring and calibration. This ... |
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| Simulation Learning PC Screen-Based vs. High Fidelity |
Aug 2011 |
66 pages |
| Authors:
Kristine Qureshi; Denise H Chadwick; Judy Carlson; Lorrie Wong; Deborah Juarez; Dale Vincent; HAWAII UNIV HONOLULU
|
| As the number and complexity of disasters increases across the world, increased attention is being paid to disaster and trauma nursing. Since 2001, the US has experienced numerous significant natural, technological and human made disasters. Presently, a large number of military nurses are directly involved in providing care to wounded soldiers on the battlefields of Iraq, Afghanistan, and other areas throughout the world. Core disaster nursing competencies have been identified, ... |
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| Hawaii Comprehensive Heart Program |
Mar 2011 |
15 pages |
| Authors:
Lawrence Burgess; HAWAII UNIV HONOLULU
|
| Heart disease is the leading cause of death in both the United States and Hawaii. According to the Hawaii State Department of Health, over 1/3 of total deaths in the state are caused by cardiovascular disease, in which approximately 18% (hospital discharges) were associated with heart failure. The potential of stem cells for use in cell therapy to treat diseased or damaged organs is very promising due to the unique ... |
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| Novel Low Cost High Efficiency Tunable RF Devices and Antenna Arrays Design based on the Ferroelectric Materials and the CTS Technologies |
14 FEB 2011 |
50 pages |
| Authors:
Magdy F. Iskander; HAWAII UNIV HONOLULU
|
| The research described in this report focused on expanding our knowledge of laser micromaching and the scope of femtosecond laser fabrication. The research addressed Army Research Office initiatives for the development of novel photonics devices and techniques that utilize nonlinear optical phenomena. The interaction of femtosecond laser pulses with polymers were studied and the conditions for device fabrication were optimized. Various ways for inducing nonlinear response in polymers devices were ... |
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| Passive Acoustic Tracking of Minke Whales |
03 JAN 2011 |
9 pages |
| Authors:
Eva-Marie Nosal; HAWAII UNIV HONOLULU
|
| This project developed model-based 3D passive acoustic tracking methods for minke whales. It was conducted in support of ONR Award N000140910489 in which T. Norris (Bio-Waves) conducted visual surveys at PMRF and S. Martin (SPAWAR) collected acoustic data on the PMRF bottom-mounted hydrophones. In this project, these data were analyzed to detect, characterize, and track minke whale calls. A minke boing detector and 3D model-based tracker was implemented. Acoustically derived ... |
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| Pacific Pediatric Advanced Care Initiative |
Jan 2011 |
71 pages |
| Authors:
Lawrence Burgess; HAWAII UNIV HONOLULU
|
| The Pacific Pediatric Advanced Care Initiative has established an advanced care center with ECLS support in Hawaii to support the Pacific Rim. The Center's goal is to advance the science of Pediatric Advanced Care through new basic science and simulation research, while providing advanced care to patients, and improving the education and training of Department of Defense (DOD) Health Care providers. The Center is evaluated through existing guidelines for clinical ... |
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| Pacific Pediatric Advanced Care Initiative |
Jan 2011 |
123 pages |
| Authors:
Lawrence Burgess; HAWAII UNIV HONOLULU
|
| The Pacific Pediatric Advanced Care Initiative has established an advanced care center with extracorporeal life support (ECLS) support in Hawaii to support the Pacific Rim. The Center s goal is to advance the science of Pediatric Advanced Care through new basic science and simulation research, while providing advanced care to patients, and improving the education and training of Department of Defense (DOD) Health Care providers. The Center has been evaluated ... |
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| Advanced Technologies Addressing Asia-Pacific Infectious Diseases |
Jan 2011 |
125 pages |
| Authors:
Duane Gubler; HAWAII UNIV HONOLULU
|
| The purpose of this program is to develop early warning disease detection systems for emerging zoonotic diseases in the Asia-Pacific, using the latest technology available, including full length sequencing, deep sequencing, and genomic and proteomic microarrays, and to understand how the evolution of dengue viruses influence epidemic potential. Each day, thousands of people throughout Asia present with illnesses that go undiagnosed. Some of these illnesses will be newly recognized diseases ... |
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| Pacific Pediatric Advanced Care Initiative |
Oct 2010 |
122 pages |
| Authors:
Lawrence Burgess; HAWAII UNIV HONOLULU
|
| The Pacific Pediatric Advanced Care Initiative establishes an advanced care Center with ECLS support in Hawaii to support the Pacific Rim. The Center will advance the science of Pediatric Advanced Care through new basic science and simulation research, while providing advanced care to patients, and improving the education and training of Department of Defense (DOD) Health Care providers. The Center will be established and evaluated through existing guidelines for clinical ... |
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| An Agent-Based Mode-change Framework for Flexible Wireless Sensor Networks (POSTPRINT) |
Jun 2010 |
10 pages |
| Authors:
Paulo Martins; HAWAII UNIV HONOLULU
|
| The next generation of wireless sensor networks (WSN) is required to cope with increasingly more complex applications and scenarios, involving a range of sensors supporting diverse functions such as the monitoring, detection and tracking of moving objects. These applications often exhibit changing, dynamic requirements, which may correspondingly require from the network some form of adaptive behavior. In this paper, we describe and propose a mode-change framework for wireless sensor networks. ... |
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| Population Size and Structure of Melon-Headed Whales (Peponocephala Electra) Around the Main Hawaiian Islands: Evidence of Multiple Populations Based on Photographic Data |
14 May 2010 |
127 pages |
| Authors:
Jessica M Aschettino; HAWAII UNIV HONOLULU
|
| Despite the presence of melon-headed whales in tropical and sub-tropical waters worldwide, little is known about this species. Melon-headed whales frequent offshore waters surrounding the Main Hawaiian Islands where aerial surveys by Mobley and colleagues suggest a relatively small population (154 individuals (CV=0.88)). A 2004 near mass-stranding in Hanalei Bay, Kaua'i occurred when an embayment of 150-200 animals coincided with naval mid-frequency sonar use. To assess population size and movements ... |
|
| Hawaii Comprehensive Heart Program |
Mar 2010 |
9 pages |
| Authors:
Lawrence Burgess; HAWAII UNIV HONOLULU
|
| Heart disease is the leading cause of death in both the United States and Hawaii. According to the Hawaii State Department of Health, over 1/3 of total deaths in the state are caused by cardiovascular disease, in which approximately 18% (hospital discharges) were associated with heart failure. The potential of stem cells for use in cell therapy to treat diseased or damaged organs is very promising due to the unique ... |
|
| Understanding Predictability of the Ocean |
Jan 2010 |
11 pages |
| Authors:
Brian Powell; HAWAII UNIV HONOLULU
|
| The long-term scientific goals of this research project are: 1. To develop an understanding of how some observations affect ocean predictability. 2. To further develop the state-of-the-art ROMS 4D-Var by extending the observational types and applications. 3. To gain experience and develop ideas for the limitations to the predictability of oceanic processes. 4. To train a new generation of students in data assimilation and ROMS. 5. As a YIP award, ... |
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| Collaborative Proposal to Extend ONR YIP research with BRC Efforts |
Jan 2010 |
6 pages |
| Authors:
Brian Powell; HAWAII UNIV HONOLULU
|
| The long-term scientific goals of this research project are: 1. To develop an understanding of how some sources of error affect ocean predictability. 2. To gain experience and develop ideas for the limitations to the predictability of oceanic processes. The primary objectives of this project are: (i) to undertand the importance of model uncertainty; (ii) to assess the influence of uncertainty on predictability; and (iii) to collaborate and learn from ... |
|
| Pacific Pediatric Advanced Care Initiative |
Oct 2009 |
215 pages |
| Authors:
Lawrence Burgess; HAWAII UNIV HONOLULU
|
| The Pacific Pediatric Advanced Care Initiative establishes an advanced care Center with ECLS support in Hawaii to support the Pacific Rim. The Center will advance the science of Pediatric Advanced Care through new basic science and simulation research, while providing advanced care to patients, and improving the education and training of Department of Defense (DOD) Health Care providers. The Center will be established and evaluated through existing guidelines for clinical ... |
|
| Exploring Deployment Experiences of Army Medical Department Personnel |
Jun 2009 |
8 pages |
| Authors:
Debra D Mark; Lynne M Connelly; Mary D Hardy; Jennifer Robison; Cheryl C Jones; Tiffany A Streett; HAWAII UNIV HONOLULU
|
| The purpose of this study was to describe Operation Iraqi/Enduring Freedom and Operation Desert Storm/Shield deployment experiences from the perspectives of 39 Army Medical Department personnel using a qualitative method in 2004. Thematic content analysis revealed themes from data collected during twelve focus groups. The themes with the most discussion that transcended across wars, branches, echelons of care, and grade were leadership and readiness concerns, followed closely by safety Issues. ... |
|
| Hawaii Energy and Environmental Technologies (HEET) Initiative |
May-2009 |
208 pages |
| Authors:
Michael J Jr; Richard E Rocheleau; Guido Bender; Maheboob Virji; Antal; Michael J Cooney; Bor Y Liaw; Stephen M Masutani; HAWAII UNIV HONOLULU
|
| This report covers efforts by the Hawaii Natural Energy Institute of the University of Hawaii under the ONR-funded HEET Initiative that addresses critical technology needs for exploration/utilization of seabed methane hydrates and development/testing of advanced fuel cells and fuel cell systems. Methane hydrates work included: hydrate thermochemistry and kinetics; environmental impacts of methane release from seafloor hydrates; hydrate engineering applications; and international collaborative R&D. In the fuel cell area, accomplishments ... |
|
| Next Generation Image Restoration for Space Situational Awareness |
09-Mar-2009 |
17 pages |
| Authors:
Stuart M Jefferies; Douglas A Hope; C A Giebink; HAWAII UNIV HONOLULU
|
| The imaging of Earth-orbiting objects using large aperture telescopes equipped with adaptive optics is a critical component of Space Situational Awareness. Unfortunately, due to limitations in the adaptive optics, compensation of the wave-front distortions imparted by the Earth's turbulent atmosphere is incomplete. Achieving the quality of imagery necessary for high confidence monitoring of the near space environment, therefore requires the use of image restoration methods to remove the unconnected component ... |
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| Understanding Predictability of the Ocean |
Jan 2009 |
5 pages |
| Authors:
Brian Powell; HAWAII UNIV HONOLULU
|
| The primary objectives of this project are: (i) to assess how particular observations may affect predictability; (ii) to assess how particular model parameterizations can affect predictability; and (iii) to compare these results with full ocean-state estimates generated from the psiEX acoustic experiment. |
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| Automated Quantification of Gradient Defined Features |
Sep-2008 |
5 pages |
| Authors:
T Fedenczuk; P Fryer; J Escartin; A J Harris; HAWAII UNIV HONOLULU
|
| We present the summary and application of a new MATLAB/GIS technique for the quantification of gradient defined features in submarine environments. The technique utilizes MATLAB scripts to convert bathymetry data into a gradient dataset, produce gradient maps, and most importantly, automate the process of defining and characterizing gradient defined features such as flows, faults, landslide scarps, folds, valleys, and ridges. The features are defined according to strict gradient threshold criteria ... |
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| Breast Density Assessment by Dual Energy X-ray Absorptiometry in Women and Girls |
Jul-2008 |
11 pages |
| Authors:
Gertraud Maskarinec; HAWAII UNIV HONOLULU
|
| Increasing evidence suggests that breast cancer risk is determined early in life. Mammographic density has been used as a biomarker for breast cancer risk because of its strong association with breast cancer. However, use of this screening method is contraindicated in young women and girls because the risk of X-ray based mammograms outweighs potential benefits in that age group. In contrast, Dual Energy X-ray Absorptiometry (DXA) has extremely low radiation ... |
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| Effects of Offshore Forcing in the Nearshore Environment |
Jan 2008 |
11 pages |
| Authors:
Geno Pawlak; Mark Merrifield; HAWAII UNIV HONOLULU
|
| The broad objective of the project is to extend our understanding on the role of offshore baroclinic forcing in nearshore dynamics. From this understanding we aim to develop modeling approaches that, combined with offshore baroclinic models, can account for the effects of offshore internal wave forcing on the circulation and sediment transport in the coastal zone. |
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| Enhanced Spatial Mapping Capabilities for the Kilo Nalu Observatory |
Jan 2008 |
5 pages |
| Authors:
Geno Pawlak; Roy Wilkens; HAWAII UNIV HONOLULU
|
| The Kilo Nalu Observatory, online since October, 2004, provides a window into the Hawaiian coastal environment. Baseline observations at Kilo Nalu include time series of currents, directional waves, temperature profiles and water chemistry at 10m and 20m depths. A high resolution spatial view of local environment is critical in establishing context for the time-series data. This spatial data is being provided via surveys using a REMUS autonomous underwater vehicle (AUV) ... |
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| Nutritional and Genetic Determinants of Early Puberty |
JUN 2007 |
6 pages |
| Authors:
Loic Le Marchand; HAWAII UNIV HONOLULU
|
| Past studies suggest that early menarche, growth velocity, and specific hormonal patterns during breast development may be critical in determining risk of breast cancer later in life. Nutritional factors during childhood and puberty, and inherited genetic factors are suspected to interact in modulating these early-life exposures. However, the biological processes involved remain poorly understood. We propose to test the relationships between nutrition, genetic factors, hormonal levels and early life events ... |
|
| Bioterrorism Preparedness for Infectious Disease (BTPID) Proposal |
JAN 2007 |
102 pages |
| Authors:
Lawrence P. Burgess; HAWAII UNIV HONOLULU
|
| Bioterrorism preparedness for infectious disease (BTPID) as part of homeland defense initiatives continues to advance. Significant opportunities exist for new research and development of bioinformatics and telecommunications solutions for BTPlD that can complement ongoing initiatives. With this in mind this funded effort with additional proposal modifications progressed from a planning study identification of problems and potential solutions analyses of potential solutions all resulting in important recommendations and knowledge. This project ... |
|
| Collaborative Research: Ground Truth of African and Eastern Mediterranean Shallow Seismicity Using SAR Interferometry and Gibbs Sampling Inversion |
05 OCT 2006 |
80 pages |
| Authors:
Benjamin A. Brooks; Francisco Gomez; Eric Sandvol; L. N. Frazer; HAWAII UNIV HONOLULU
|
| We evaluate the use of Synthetic Aperture Radar Interferometry (InSAR) to provide GT5 or better locations for shallow earthquakes of moderate size (Mw 5 - 6.5) in primarily Africa and the Middle East, although we also included some events from Asia. We find that InSAR is capable of routine detection of surface displacements associated with small ( |
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| Development of High-Resolution Acoustic Camera Based Real-Time Object Recognition System by Using Autonomous Underwater Vehicles |
Sep-2006 |
7 pages |
| Authors:
Son-Cheol Yu; Tae-Won Kim; Akira Asada; Scott Weatherwax; Ben Collins; Junku Yuh; HAWAII UNIV HONOLULU
|
| This paper addresses acoustic camera DIDSON based object recognition method for AUVs(Autonomous Underwater Vehicles). The acoustic camera's characteristics and display method based on various experiments and the acoustic camera model and efficient and reliable image recognition method for AUVs are proposed. As examples, the cubic and cylindrical objects modeled to simulate the image and their recognition test was carried out in experimental tank. |
|
| Hawaii Energy and Environmental Technologies (HEET) Initiative Phase 4 |
AUG 2006 |
262 pages |
| Authors:
Richard E. Rocheleau; HAWAII UNIV HONOLULU
|
| This report summarizes work conducted by the Hawaii Natural Energy Institute of the University of Hawaii under the Hawaii Energy and Environmental Technologies (HEET) Initiative funded through the Office of Naval Research. This initiative focused on critical technology needs associated with the exploration and utilization of seabed methane hydrates and the development and testing of advanced fuel cells and fuel cell systems. The efforts in methane hydrates comprised four primary ... |
|
| Nutritional and Genetic Determinants of Early Puberty |
JUN 2006 |
17 pages |
| Authors:
Loic LeMarchand; HAWAII UNIV HONOLULU
|
| Past studies suggest that early menarche, growth velocity, and specific hormonal patterns during breast development may be critical in determining risk of breast cancer later in life. Nutritional factors during childhood and puberty, and inherited genetic factors are suspected to interact in modulating these early-life exposures. However, the biological processes involved remain poorly understood. We propose to test the relationships between nutrition, genetic factors, hormonal levels and early life events ... |
|
| Asia Pacific Military Medicine Conference (APMMC) Simulation Symposium (16th) Held in New Delhi, India on March 26-31, 2006. Abstracts |
APR 2006 |
|
| Authors:
Dale S. Vincent; HAWAII UNIV HONOLULU
|
|
| Bioterrorism Preparedness for Infectious Disease Proposal |
01-Jan-2006 |
120 pages |
| Authors:
Lawrence P Burgess; HAWAII UNIV HONOLULU
|
| This effort helped to support the establishment of a Joint Clinical Research Center (JCRC) in Thailand in a partnership with the Royal Thai Army (RTA), the Armed Forces Research Institute of Medical Science (AFRIMS), and the University of Hawaii. The Center will provide a vehicle for the study of infectious diseases (including bioterrorism) with full patient, laboratory and animal facilities. There remains significant difficulty in providing timely research when the ... |
|
| Diabetes Care and Treatment Program: A Joslin Telemedicine Initiative |
01 Jan 2006 |
65 pages |
| Authors:
Deborah Birkmire-Peters; Dale S Vincent; Joseph Humphry; Kari-Jo Parisi; HAWAII UNIV HONOLULU
|
| The major goals of this continuing project are the establishment of a telemedicine system for comprehensive diabetes management and the assessment of diabetic retinopathy that provides increased access for diabetic patients to appropriate care, that centralizes the patients in the care process, that empowers the patient to better manage their disease, that can be performed in a cost effective manner, and that maintains the high standard of care required for ... |
|
| EcoHealth Consortium Workshop on Emerging Infectious Diseases and Information Technology |
Oct 2005 |
10 pages |
| Authors:
Bruce A Wilcox; Kristin Duin; Andrew Hood; HAWAII UNIV HONOLULU
|
| During March 9-11 2005 a meeting was convened by the East West Center and the Asia-Pacific Institute of Tropical Medicine and Infectious Diseases at the University of Hawaii as part of National Institutes of Health Roadmap initiative Research Teams of the Future. The meeting was entitled Emerging Infectious Diseases and Social-Ecological Systems. The purpose of this meeting was to advance interdisciplinary methods for investigation of the problem of emerging infectious ... |
|
| Genetic Plymorphisms, Estrogens, and Breast Density |
JAN 2005 |
48 pages |
| Authors:
Gertraud Maskarinec; HAWAII UNIV HONOLULU
|
| This study investigated the association between genetic polymorphisms in hormone producing and metabolizing enzymes and several markers of breast cancer risk among women of different ethnic background. The specific aims were to analyze the relation of breast density and estrogen levels in urine and serum with the presence of variant alleles in CYP17, COMT, CYP1A1, CYP1A2, and CYP1B1, to describe ethnic differences in urinary excretion levels of estrogen, and to ... |
|
| Bioterrorism Preparedness for Infectious Disease |
JAN 2005 |
163 pages |
| Authors:
Lawrence Burgess; HAWAII UNIV HONOLULU
|
| Bioterrorism preparedness for infectious disease (BTPID) as part of homeland defense initiatives is advancing rapidly, with the Center for Disease Control (CDC) taking the lead in mandating improved surveillance and management for States to follow, centered around 6 major focus areas with 17 critical capacities. Significant opportunities exist for new research and development of bioinformatics and telecommunications solutions for BTPID that would complement CDC led initiatives. The objectives of this ... |
|
| Modeling of Sediment Mechanics for Mine Burial Prediction |
DEC 2004 |
11 pages |
| Authors:
Horst G. Brandes; H. R. Riggs; HAWAII UNIV HONOLULU
|
| Numerical model development and testing were carried out for the purpose of assessing the influence of seafloor liquefaction on the burial of mines in shallow water due to cyclic loading by surface water waves. This project was conducted as part of the Office of Naval Research Mine Burial Prediction program (Code 321). |
|
| UH-USA Agreement - A Telemedicine Research Proposal |
NOV 2004 |
451 pages |
| Authors:
Lawrence P. Burgess; Deborah P. Birkmire-Peters; HAWAII UNIV HONOLULU
|
| The purpose of the University of Hawaii Telemedicine Curriculum Research Project is to develop an effective web-based curriculum for training military healthcare personnel in the use of contemporary communication, automation, and informatics technology in the delivery of healthcare. The overall curriculum is generic in nature, while specific modules can be tailored to the needs of the military healthcare provider (HCP). The goal of the telemedicine curriculum is to impart both ... |
|
| A Longitudinal Study of Emotional Distress and the Use of Complementary and Alternative Medicine in Women with Breast Cancer |
SEP 2004 |
87 pages |
| Authors:
Dianne M. Shumay; Gertraud Maskarinec; HAWAII UNIV HONOLULU
|
| The study purpose is to examine the extent to which levels of depression and anxiety and coping at 3-5 months post-diagnosis are related to complementary and alternative medicine (CAM) use at initial assessment (T1) and follow-up at 9 (T2) and 15 (T3) months. This study will also identify the types of CAM sought after by women with higher levels of anxiety and depression. Seventy-one women completed the survey at T1 ... |
|
| Semi-Synthesis and In-vitro Anticancer Evaluation of Derivatives of a New Microtubule Poison with a Taxol-Like Mechanism |
SEP 2004 |
10 pages |
| Authors:
Thomas K. Hemscheidt; HAWAII UNIV HONOLULU
|
| Taccalonolides are plant-derived steroids which act as microtubule poisons on mammalian cells with a taxol-like mechanism. This makes them potentially useful lead compounds for thedevelopment of anti-cancer agents specifically breast cancer. Natural taccalonolide A was modified through selective chemical reactions at various sites in the molecule in preparation for biological tests that will compare the biological effects and potency of the derivatives with that of the starting material. These studies ... |
|
| Semi-Synthesis and In-Vitro Anticancer Evaluation of Derivatives of a New Microtubule Poison with a Taxol-Like Mechanism |
SEP 2003 |
7 pages |
| Authors:
Thomas U. Hemscheidt; HAWAII UNIV HONOLULU
|
| Taccaldnolides are structurally unusual steroid derivatives with microtubule-stabilizing, i.e. Tasol-like activity. The aim of the work is definition of a minimal structural motif that on the one had simplifies' the structure but improves of at least retains potency as an antimitotic. Taccalonolide E, a minor compound found in Tacca chantrieri, has been found to be a more potent cytotoxin that taccalonolide A. The two compounds differ by additional oxygenation in ... |
|
| A Longitudinal Study of Emotional Distress and the Use of Complementary and Alternative Medicine in women with Breast Cancer |
SEP 2003 |
32 pages |
| Authors:
Dianne M. Shumay; HAWAII UNIV HONOLULU
|
| The study purpose is to examine the extent to which levels of depression and anxiety and coping at three-five months post-diagnosis are related to complementary and alternative medicine (CAM) use at initial assessment and follow-up at 9 and 15 months. This study will also identify the types of CAM sought after by women with higher levels of anxiety and depression. Additional aims of the study are to provide pilot data ... |
|
| Genetic Polymorphisms, Estrogens, and Breast Density |
AUG 2003 |
30 pages |
| Authors:
Gertraud Maskarinec; HAWAII UNIV HONOLULU
|
| During this year we have completed the genotyping and urine analysis for estrogen metabolites and proceeded with the statistical analysis. We have completed two investigations that addressed the following specific aims: 1. To examine the association between polymorphism in genes coding for metabolism and biosynthesis of estrogens (COMT CYP1A1, CYP1A2, CYP1B1, and CYP17) and mammographic densities in healthy women with different ethnic backgrounds. 2. To analyze the relation of mammographic ... |
|
| UH - USA Agreement - A Telemedicine Research Proposal |
JAN 2003 |
311 pages |
| Authors:
Lawrence P. Burgess; HAWAII UNIV HONOLULU
|
| The purpose of the University of Hawaii Telemedicine Curriculum Research Project is to develop an effective web-based curriculum for training military health care personnel in the use of contemporary communication, automation, and informatics technology in the delivery of health care. The overall curriculum is generic in nature, while specific modules can be tailored to the needs of the military health care provider (HPC). The goal of the telemedicine curriculum is ... |
|
| Cementation Processes of Naturally Aged Hawaiian Calcarerous Sands |
DEC 2002 |
114 pages |
| Authors:
Thomas B. McLemore; HAWAII UNIV HONOLULU
|
| Researchers have studied cementation of calcareous sands for decades. While cementation increases static and cyclic strengths, it also reduces skin friction on piles. Cementation of sands in their own environment varies widely with many different factors. Obtaining undisturbed samples can be difficult and costly, and laboratory reproduction of samples has become an accepted method for testing calcareous materials. The focus of this research is on understanding the processes and effects ... |
|
| Semi-Synthesis and In-Vitro Anticancer Evaluation of Derivatives of a New Microtubule Poison with a Taxol-Like Mechanism |
SEP 2002 |
8 pages |
| Authors:
Thomas Hemscheidt; HAWAII UNIV HONOLULU
|
| In prior research we had discovered a steroid-like molecule with antimicrotubule activity of the Taxol-like mechanism of action from a tropical ornamental plant. There are only a few molecules known that have this type of activity. One of these is clinically used, the second one, the epothilones, is under development. The aim of the present award is to modify the structure of the compound we have discovered in order to ... |
|
| A Longitudinal Study of Emotional Distress and the Use of Complementary and Alternative Medicine in Women with Breast Cancer |
SEP 2002 |
43 pages |
| Authors:
Dianne M. Shumay; Gertraud Maskarinec; HAWAII UNIV HONOLULU
|
| The study purpose is to examine the extent to which levels of depression and anxiety and coping at three-five months post-diagnosis are related to complementary and alternative medicine (CAM) use at initial assessment and follow-up at 9 and 15 months. This study will also identify the types of CAM sought after by women with higher levels of anxiety and depression. Additional aims of the study are to provide pilot data ... |
|
| Genetic Polymorphisms, Estrogens, and Breast Density |
AUG 2002 |
9 pages |
| Authors:
Gertraud Maskarinec; HAWAII UNIV HONOLULU
|
| Mammographic density appears to be a strong predictor of breast cancer risk. Endogenous steroid hormones have been shown to be important in the development and progression of breast cancer. Because some metabolites of endogenous estrogens may have more estrogenic effects than others, genetically determined differences in biosynthesis and metabolic pathways of estrogens may affect breast cancer risk. This study will address the following specific aims: 1. To examine the relation ... |
|
Reports by Corporate Author
