ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

Toxicological Study No. 75-51-YJ81-93, 4-Amino-2-Nitrotoluene (4A2NT) Oral Approximate Lethal Dose 14-day Range Finding 90-Day Subchronic Feeding Studies in Rats, August 1991-November 1993

Jul 1994

189 pages

Authors: John T Houpt; Glenn J Leach; ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

The full text of this report is available for sale.

The subchronic study examined the toxicity of 4-Amino 2-Nitrotoluene (4A2NT) in rats following oral administration in feed for 90 days. associated with the administration of 4A2NT in rats was testicular hypspermatogenesis (atrophy) a higher incidence of cardiomutagenicity, myopathy, anemia and high incidence of hepatocellular cytoplasmic vacuolization. A no observed adverse effect level in the 90-day was not established. the lowest-observed-adverse-effect-level in the 90-day study was 27 mg/kg/day for males and ...

Developing an Integrated Solid Waste Management Plan: A Guide for Army Installations

OCT 93

27 pages

Authors: ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

This technical guide was developed to reflect U.S. Environmental Protection Agency (EPA) requirements for state solid waste management plans, with the presumption that Army facilities will face similar requirements. It is also a response to a need to introduce integrated solid waste management to the Army community. The guide reflects a compilation of various states' requirements concerning the contents of solid waste management plans. Although specific state requirements may vary, ...

A Commander's Guide to Childhood Lead Poisoning Prevention/Lead-Based Paint Management Program on DoD Installations

JUN 93

16 pages

Authors: ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

Provide current information and guidance for commanders to establish a Childhood Lead Poisoning Prevention (CLPP)/Lead-Based Paint Management (LBPM) Program on their installations

Safety, Health, and Fire Prevention Guide for Hospital Safety Managers

01 MAR 93

45 pages

Authors: Pam Weiss; ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

Participation in hospital safety programs is essential for all military and civilian employees. This guide outlines a variety of safety, health, and fire prevention issues and provides a ready reference for more detailed information.... Safety management, Hospitals, Fire prevention, Laboratory safety, Laboratory fires.

Preliminary Assessment of the Oral Toxicity of 1,5-Diazido-3- Nitrazapentane, 2- and 6-Week Feeding Study, Male and Female Rats

FEB 93

38 pages

Authors: Everett A. Haight; John G. Harvey; Patricia A. Bell; ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

A 2 and 6 week gavage feeding of DANPE caused testicular hypospermatogenesis in male rats and pneumonitis in female rats. A NOAEL was not achieved in male rats but was achieved in female rats at the 56.00 mg/kg/day dose level.... 1,5-Diazido-3-Nitrazapentane (DANPE), Gavage, Testicular hypospermatogenesis, Insterstitual Inflammation No-observed-Adverse-Effect- Level(NOAEL), Feeding study.

Trichloromelamine 14-Day Range Finding and 90-Day Subchronic Studies in Rats. 3 August 1988 - 17 January 1989. Phase 2

13 NOV 92

73 pages

Authors: Mark Michie; Richard A. Angerhofer; ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

The subchronic study examined the toxicity of the food service disinfectant trichloromelamine (TCM) in rats following oral administration-for 90 days. Associated with the administration of TCM in rats were lesions in the stomach and trachea, while also causing engorgement of the small blood vessels of the adrenals, brain, kidneys, liver, lung and pituitary. The no observed adverse effect level in the 90-day study was 30 mg/kg/day. Trichloromelamine should be considered ...

Guide to Managing Occupational Exposure to Bloodborne Pathogens

OCT 92

243 pages

Authors: ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

Procedures for the Diagnostic Dose Resistance Test Kits for Mosquitoes, Body Lice, and Beetle Pests of Stored Products

01 AUG 92

38 pages

Authors: Brian Zeichner; ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

In military operations, the control of medically important insect pests (such a mosquitoes, body lice, and beetle pests of stored products) is essential in preventing disease and the loss of food. The use of effective insecticides will maximize the control success. Public health insect pests' resistance to insecticides has been documented from around the world. The possibility of resistance affecting control should be considered before any disease vector control operation. ...

Laser Measurement Techniques Guide for a Hazard Evaluation

AUG 92

26 pages

Authors: Terry Lyon; ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

This technical guide provides uniform DOD guidance when performing radiometric measurements upon laser systems to conduct a hazard evaluation. This guide was prepared for the Laser System Safety Working Group to provide same joint service standardized techniques for laser measurements and the hazard evaluation of military laser systems. This technical guide should facilitate acceptance of hazard evaluations performed by other services. Although this technical guide could be applied to any ...

Preliminary Assessment of the Relative Toxicity of 1,5-Diazido-3- Nitrazapentane 90-Day Dermal Application Male and Female Rabbits Study Number 75-51-Y809-90, May 1990 - June 1992. Phase 2

JUN 92

43 pages

Authors: Everett A. Haight; John G. Harvey Jr.; Patricia Beall; ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

A 90-day application of DANPE has the potential to cause testicular hypospermatogenesis in male rabbits and an apparent inhibition of mature ovarian follicles formation in female rabbits. A no-observed-adverse-effect-level was not achieved in the male rabbits but was achieved in female rabbits at 27.3 mg/ kg dose level.... 1,5-Diazido-3-Nitrazapentane, Dermal, Approximate Lethal Dose (ALD), Testicular hypospermatogenesis, Ovarian follicle No-observed-adverse- effect-level (NOAEL).

Topical Hazard Evaluation Program, Assessment of the Relative Toxicity of Candidate Insect Repellants, AI3-36465, AI3-37410, AI3-37414, AI3-37416, AI3- 37577, AI3-38661, AI3-54169, AI3-54170, AI3-20698, AI3-38142, AI3-39672. U.S. Department of Agriculture

APR 92

21 pages

Authors: ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

Topical Hazard Evaluation Program, Assessment of the Relative Toxicity of Candidate Insect Repellents. Executive Summary

FEB 92

19 pages

Authors: ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

Acute Toxicity Preliminary Assessment of the Relative Toxicity of 1,5- Diazido-3-Nitrazapentane, January 1989 - February 1992

FEB 92

23 pages

Authors: ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

A Preliminary Assessment of the Relative Toxicity of 1,5-Diazido-3- Nitrazapentane (DANPE) was completed in February 1992. The report is enclosed. The DANPE is fairly toxic by dermal absorption and by ingestion. The compound has no potential for causing sensitization. The DANPE exhibited increases in chromosomal aberrations and a positive mutagenic response in cell culture. The following paragraphs are recommendations based on professional scientific judgment: Conduct further toxicological studies with DANPE ...

Acute Toxicity Preliminary Assessment of the Relative Toxicity of 1,5- Diazido-3-Nitrazapentane. Phase 1

FEB 92

24 pages

Authors: Everett A. Haight; John G. Harvey Jr.; Charles E. Watson; ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

The DANPE is fairly toxic by dermal absorption and ingestion. The compound has no potential for causing sensitization. The DANPE exhibited increases in Chromosomal Aberrations and a positive mutagenic response in cell culture.

Guide to Commensal Rodent Control

DEC 91

101 pages

Authors: Richard E. Griffith Jr; ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

This technical guide (TG) is an introduction to basic commensal rodent biology and control methods. It covers the three species of commensal rodents found worldwide plus limited information on the Polynesian rat and five genera of North American wild rodents that also interact with man's interests. It is intended for use by persons interested in commensal rodent control in the United States and its Possessions. This information was compiled from ...

Dermal Penetration of 14C-Labeled Diisopropyl Methylphosphonate in Swine

OCT 91

Authors: Hubert L. Snodgrass; LeRoy W. Metker; ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

The full text of this report is not available and therefore is not for sale. This information is provided for reference purposes only.

DIMP is a water contaminant resulting from the manufacture of the chemical warfare agent GB. To determine its potential contribution to human exposure, its dermal penetration was assessed in swine. Pigs received a single dermal application of 14C-labeled DIMP at one of three exposure levels, i.e., 400, 40, or 4 micro g/cm2 of skin. Absorption was quantitated by measuring radiocarbon in the urine or feces through 7 days and in ...

Pentachlorophenol-Treated Materials

30 SEP 91

38 pages

Authors: Murray Brown; Linda Baetz; ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

In the past, pentachlorophenol (penta), a preservative for wood used outdoors, was primarily used by the Department of the Army (DA) for preserving ammunition boxes and pallets. While the Department of Defense (DoD) no longer procures penta-treated wood, existing stocks are significant. This guide provides information on penta-treated materials to assist-- (a) Personnel responsible for handling, transporting, and disposing of penta in: Recognizing and controlling penta exposures. Recommending proper penta ...

Preliminary Assessment of the Relative Toxicity of Tetraglycine Hydroperiodide, January 1988-August 1991. Phase 1

AUG 91

29 pages

Authors: Joseph A. Macko Jr; ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

Toxicity of Technical Grade Tetraglycine Hydroperiodide (TGHP), the active ingredient in a military water purification tablet (MIL-W-283) has been completed. TGHP is moderately toxic by ingestion when prepared as a aqueous slurry. The compound has no potential for causing sensitization. However, TGHP did produce mild but reversible primary skin irritation, and the technical grade powder did cause severe and nonreversible injury to the eye. TFHP did not exhibit mutagenic activity ...

Personal Protective Techniques against Insects and Other Arthropods of Military Significance

01 JUN 91

Authors: Sandra R. Evans; ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

Historically, in most military conflicts, combat power has been reduced more significantly by disease and nonbattle injuries (DNBI) than from direct combat casualties. A large number of diseases affecting the troop strength of deployed units is directly attributed to disease-carrying arthropods. Moreover, arthropods can inflict severe physical, psychological, and economic stresses which threaten the military mission. Not only do they transmit disease, but the bites they inflict can be painfully ...

National Pollutant Discharge Elimination System (NPDES) Permit Application Requirement for Storm Water Discharges

MAY 91

55 pages

Authors: Mike Robison; ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

Under the Water Quality Act of 1987, storm water discharge permits are to be in pace by 1 October 1992. Federally-owned collection systems are designated as nonmunicipal systems, and therefore are required to meet the rules dealing with storm water discharges associated with 'industrial activities.' Most Army installations will be affected because the definition of an 'industrial activity' includes several activities not typically considered as industrial, including waste water treatment ...

Assessment of Dermal and Ocular Effects of Topical Skin Protectant Formulations ICD-1536 (Lot no. 11 Jan 91 BH) and ICD 1536 (Lot no. 03 Jan 91 AH) May 1991

MAY 91

Authors: Hubert L. Snodgrass; ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

Two separate lots of ICD-1536, a topical skin protectant formulation, were evaluated for skin, eye, and photochemical irritation in rabbits. Lot No. 11 Jan 91 BH caused moderate primary skin irritation with erythema persisting through 7 days. It also produced minimal eye irritation but no photochemical irritation. It was recommended that the material be used with caution on human skin and that a prophetic patch test be performed on man ...

Assessment of the Development Toxicity of Zinc Naphthenate in Rats. Phase 4

28 MAR 91

32 pages

Authors: Richard A. Angerhofer; Mark W. Michie; Mary P. Barlow; Particia A. Beall; ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

This study was designed to detect any potential developmental toxicity and/or teratogenic hazard associated with the use of zinc naphthenate as a wood preservative. Oral administration of zinc naphthenate to rats during the major period of fetal organogenesis did not result in teratogenic effects. Transient maternal toxicity was confined to the highest dosage group (938 mg/kg/ day) and consisted of lethargy and lower body weight gain. Maternal treatment at that ...

Laser Hazards Bibliography, January 1991

31 JAN 91

278 pages

Authors: David H. Sliney; Anita Robinson; Shawn Sparks; ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

The Laser Hazards Bibliography consists of 3414 references in the open literature broken into subject categories which relate to general biological effects, the eye, the skin, laser safety, laser propagation in the atmosphere, and laser measurements.

Industrial Hygiene Air Sampling and Bulk Sampling Instructions

DEC 90

73 pages

Authors: Rosemary Gaffney; ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

This technical guide describes air and bulk industrial hygiene sampling procedures for over 100 potentially hazardous chemical contaminants. The guide contains air volumes, sampling rates, and references for IH air sampling. It addresses the types of containers and the amount of sample required for bulk samples. Procedures for submitting samples including a listing of Army laboratories that perform industrial hygiene chemistry analysis are provided. The guide lists the expendable monitoring ...

90-Day Feeding Study in Rats with Chemical Decontaminant DS-2

SEP 90

26 pages

Authors: John G. Harvey Jr.; Everett A. Haight; ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

A 90-day feeding study was performed with rats to determine the oral toxicity od the Chemical Decontaminant DS-2. Results of this testing indicated severe toxicity at the levels tested, producers death, severe weight loss, reproductive and lung pathology and organ-to-body weight ratios. Recommendations provide for wearing of protective equipment when handling DS-2 following decontamination procedures and development of sampling strategies for determining residual levels at DS-2.

Preliminary Assessment of the Relative Toxicity of the Candidate Insect Repellent 1-(3-Cyclohexen-1-Ylcarbonyl)piperidine AI3-35765 Acute Toxicity

AUG 90

28 pages

Authors: Maurice H. Weeks; ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

The compound AI3-35765 is comparatively non-toxic by ingestion and by dermal absorption. It has no potential for causing dermal sensitization and does not exhibit mutagenic activity in cell culture. No hazard exists from short-term inhalation of its saturated vapors. The technical grade may cause moderate, but reversible, injury to the eye. Recommend conducting further entomological and toxicological studies with AI3-35765 to determine if candidate compound meets the requirements for an ...

Assessment of the Developmental Toxicity of Propylene Glycol Monomethyl Ether Acetate (PM Acetate) in Rats

DEC 89

28 pages

Authors: Arthur E. Asaki; John T. Houpt; ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

This study evaluated the potential maternal, embryotoxic and teratogenic parameters of propylene glycol monomethyl ether acetate in Sprague- Dawley rats following inhalation of vapors in days 6-15 of gestation. No teratological or other developmental effects were seen in fetuses at air concentrations as high as 4000 parts per million, in spite of slight toxic effects in dams at concentrations as low as 500 ppm. It is recommended that a) an ...

Laser Hazards Bibliography

31 OCT 89

236 pages

Authors: David H. Sliney; Anita Robinson; ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

Topical Hazard Evaluation Program (THEP) Assessment of the Relative Toxicity of Candidate Insect Propellents AI3-38306, AI3-38315, AI3-38530, AI3- 39041, AI3-39076, AI3-39077, AI3-39078, AI3-39085, U.S. Department of Agricultural Proprietary Chemicals Stu

JUN 89

18 pages

Authors: Maurice H. Weeks; ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

The purpose of the Topical Hazard Evaluation Program (THEP) is to investigate relevant health endpoints of proposed insect repellent chemicals. Data from these studies are used to recommend the course of further entomological and toxicological evaluations with subject chemicals. The results from the current animal sensitization studies showed that two of the eight test compounds AI3-39076 and AI3-39077 have some potential for causing an allergic response in man. A positive ...

Validation of a Sorbent Tube/High Performance Liquid Chromatographic Procedure for the Determination of Eight Explosives in Water

JUN 89

55 pages

Authors: Robert J. Valis; Toni A. Bishop; Kenneth E. Williams; ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

A new analytical method for the determination of eight explosives in ground water was independently validated. The following eight explosives were studied: HMX, RDX, Tetryl, TNT, PETN, Nitroglycerin, 2,6-DNT, and 2,4-DNT. The same method had been recently developed and validated by Battelle Laboratories, Columbus Div. USAEHA Certified Reporting Limits range from 0.8 to 22 micrograms/ Liter, whereas Battelle values had ranged from 0.9 to 15 micrograms/Liter. The method involved collection ...

Topical Hazard Evaluation Program (THEP) Assessment of the Relative Toxicity of Candidate Insect Repellents AI3-26881, AI3-37430 and AI3-38269 U.S. Department of Agricultural Proprietary Chemicals, May 1989

MAY 89

Authors: Maurice H. Weeks; ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

The purpose of the Topical Hazard Evaluation Program (THEP) is to investigate relevant health endpoints of candidate insect repellents. Data from these toxicological studies are used to recommend the course of further entomological and toxicological evaluations. Comparison of the results from the present eye irritation studies with previously reported data showed that AI3- 37430 and AI3-38269 caused only mild injury to the eye while AI3-26881 continued to produce severe injury. ...

Assessment of the Relative Toxicity of Candidate Insect Repellent 1-(3- Cyclohexex-1-YL Carbonyl) Hexahydro-1H-Azepine, AI3-35766, Study No. 75-51-0491- 89

JAN 89

Authors: Maurice H. Weeks; John G. Harvey; ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

A series of studies was performed in laboratory animals and in vitro biological systems to determine the relative toxicity of the candidate insect repellent, AI3-35766. The studies indicated that the subject compound exhibited a potential for skin irritation, eye irritation sensitization, and mutagenicity. It was recommended that no further laboratory studies be conducted on the candidate repellent AI3-35766. (aw)

Preliminary Assessment of the Relative Toxicity of Copper Naphthenate, (Mooney Chemicals), Acute Studies. Phase 3. May 1984 - October 1987

16 NOV 88

Authors: Richard A. Angerhofer; LeRoy W. Metker; ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

A series of studies was performed in laboratory animals and biological systems to determine the relative toxicities of copper naphthenate and a wood preservative formulation thereof (M-Gard W-510, Mooney Chemicals). The studies included primary skin and eye irritation, acute, oral and dermal toxicity, skin sensitization, saturated vapor inhalation, dominant lethal studies, avian toxicity and aquatic toxicity. The results of this testing indicated that M-Gard W-510 has the potential of cause ...

The Effects of Laundering on the Permethrin Content of Impregnated Military Fabrics

OCT 1988

34 pages

Authors: Hubert L. Snodgrass; ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

The insecticide permethrin, when impregnated into the military Battle Dress Uniform (BDU), is remarkably effective in repelling bites from disease bearing insects. In practice, however, both wear and laundering will likely affect the insecticidal level within the BDU cloth and may alter the leaching rate of permethrin out of the fabric. To address these issues, both cotton and NYCO (50/50 nylon-cotton) BDU fabrics were impregnated with c14 labeled permethrin, then ...

Migration of Permethrin from Military Fabrics Under Varying Environmental Conditions. Phase 2

13 SEP 88

Authors: Hubert L. Snodgrass; Patricia A. McGreal; ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

Clothing treated with the insecticide permethrin offers near complete protection against insect vectors when used in conjunction with topical insect repellents. Of concern is the leaching of permethrin from the military battle dress uniform (BDU) and the potential for skin absorption by the wearer. Migration of permethrin from two types of BDU fabrics, 100 percent cotton and a nylon/cotton blend (NYCO), was tested in animals. Swatches of fabric (50 cm2) ...

The Strategic Performance of Defensive Barriers

MAY 88

39 pages

Authors: Paul B. Seguin; ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

This monograph was prepared by the US Army Engineer Studies Center for the Combined Forces Command of the Republic of Korea and the United States. It reviews the strategic performance of barrier and fortification systems built by a variety of countries in the 19th and 20th centuries for lessons applicable to the design of a future Korea Barrier System. Those systems built in peacetime for the purposes of deterring invasion ...

Evaluation of Thermal Batteries for Hazardous Waste Characteristics

28 MAR 88

7 pages

Authors: Michael H. Diem; ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

Thermal batteries data was reviewed to determine their hazardous waste characteristics under United States environmental regulations. The study concludes that thermal batteries are hazardous waste, and that the electrochemical system in the battery determines its hazardous waste characteristics. Some batteries exhibit toxicity, and other reactivity.

Effects of Ingestion of Zinc Naphthenate on the Reproduction Function of Rats. Phase 5

FEB 88

31 pages

Authors: Mark W. Michie; Richard A. Angerhofer; Mary P. Barlow; Patricia A. Beall; ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

This study was conducted to determine the effects on reproduction, if any, of oral administration to rats of a candidate wood preservative, zinc naphthenate. findings indicated that rats fed a diet of 0.5% zinc naphthenate experienced a significant weight loss. This weight loss had no effect on mating or viability of offspring over two generations of rats on study. Therefore, zinc naphthenate was not considered to be a reproductive hazard ...

Preliminary Assessment of the Relative Toxicity of Copper Naphthenate Acute Studies. Phase 2. May 1984 - June 1986

05 JAN 88

Authors: Richard A. Angerhofer; Lynn M. Taylor; ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

A series of studies was performed in laboratory animals and biological systems to determine the relative toxicities of copper naphthenate and a wood preservative formulation thereof. The studies included primary skin and eye irritation, acute oral and dermal toxicity, skin sensitization, saturated vapor inhalation, mutagenicity screening, dominant lethal studies, avian toxicity and aquatic toxicity. The results of this testing indicated that Cunapsol 5 has the potential to cause severe irritation ...

Topical Hazard Evaluation Program of Candidate Insect Repellents AI3- 38426, AI3-39008, AI3-39010, AI3-30106, AI3-38264, AI3-38265, AI3-38098, AI3- 38099 and AI3-5903, U.S. Department of Agricultural Proprietary Chemicals, January 1988

JAN 88

Authors: Maurice H. Weeks; ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

The purpose of this report is to provide guidance for further entomological testing of the subject candidate insect repellents by means of laboratory animal studies. In addition, these data may be useful in developing preliminary safety guidelines for handling these compounds. Based on professional scientific judgement, the following recommendations are offered. a. Approve compounds AI3-38426, aAI3-39008, AI3-39010, AI3-30106, AI3-38264, AI3- 38265, AI-38098, AI3-38099, and AI3-5903 for further entomological testing. b. ...

Fabric/Skin Contact from Wearing the Army Battle Dress Uniform, June- July 1987

JUL 87

Authors: Hubert L. Snodgrass; ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

Military fabrics are routinely treated with substances to extend their useful life expectancy, and with clothing, to enhance the well-being of the wearer. Of concern is the leaching out of impregnants and their availability for skin absorption. Prediction of dose in man requires the quantitation of the skin/fabric interface. The present study determined the fabric/skin contact area by dressing a mannequin in the standard issue Battle Dress Uniform (BDU) then ...

Guidelines for the Preparation, Administration, and Disposal of Cytotoxic Drugs

MAY 87

Authors: Sharon L. Noll; Daniel J. Caldwell; ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

This technical guide presents current guidance for the preparation, administration, and disposal of cytotoxic drugs (CDs). Some antineoplastic (anticancer) drugs used in cancer chemotherapy are also cytotoxic. Because they are toxic to living cells, health care workers may be exposed to significant health hazards during the preparation and handling of these drugs. Appendix C lists many antineoplastic agents currently in use.

Topical Hazard Evaluation Program of Candidate Insect Repellent AI3- 39053a

MAY 87

11 pages

Authors: ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

Purpose of report is to provide guidance for further entomological testing of the Candidate Insect Repellent A13-39053a by means of laboratory animal studies using Sprague-Dawley rats, New Zealand White rabbits, and allbino-Hartley guinea pigs. In addition, these data may be useful in developing preliminary safety guidelines for handling this compound. Based on professional scientific judgement, the following recommendations are offered. AI3-39053a should be approved for more extensive entoomological and toxicological ...

Chemical Stockpile Disposal Program. Evaluation of Multiple Incinerator Air Quality Impacts Edgewood Area Aberdeen Proving Ground

MAY 87

15 pages

Authors: ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

The purpose of this study was to examine the long-term additive ambient impact of certain toxic air pollutants that will potentially be emitted from Chemical Agent Incinerator (AI) proposed for the Edgewood Area (EA) of Aberdeen Proving Ground (APG), Maryland and from three additional planned or existing incinerators also located on the EA. this impact was determined in consideration of the existence and operation of three additional planned or existing ...

Safety and Fire Prevention Guide for Hospital Safety Managers

APR 87

Authors: Harry Andrew; ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

This technical guide provides guidance to individuals responsible for safety and fire prevention in Army hospitals. It may also be a valuable tool to the experienced full-time safety person who has never worked in a hospital and to military personnel who have been assigned safety and fire prevention responsibility as a collateral duty. This guide is not meant to cover all of the day-to-day safety and fire prevention situations nor ...

Topical Hazard Evaluation Program of Candidate Insect Repellent AI3- 36328-B 1((6-Methyl-3-Cyclohexen-1-YL)Carbonyl) Pyrrolidine, Mar 1987

APR 87

Authors: Maurice H. Weeks; William T. Muesham; ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

Guidance for entomological testing of the Candidate Insect Repellent AI3-36328-b, 1-((6-methyl-3-cyclohexen-2-yl) carbonyl)pyrrolidine, irritation, skin, eye, toxic hazards, toxicity.

Preliminary Assessment of the Relative Toxicity of Zinc Naphthenate

APR 87

Authors: Richard A. Angerhofer; Lynn M. Balczewski; ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

A series of studies were performed in laboratory animals and biological systems to determine the relative toxicities of zinc naphthenate and a wood preservative formulation thereof. The studies included primary skin and eye irritation, acute oral and dermal toxicity, skin sensitization, saturated vapor inhalation, mutagenicity screening, dominant lethal studies, avian and aquatic toxicities, and Shimkin Mouse Assay. The results of this testing indicated that the test materials have a relatively ...

Industrial Hygiene Sampling Instructions

MAR 87

54 pages

Authors: Frederic Belkin; Richard W. Bishop; ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

This technical guide describes air and bulk industrial hygiene sampling procedures for over 100 potentially hazardous chemical contaminants. The guide contains air volumes, sampling rates and references for IH air sampling. It addresses the types of containers and amount of sample required for bulk samples. Procedures for submitting samples including a listing of Army laboratories that perform industrial hygiene chemistry analysis are provided. The guide lists the expendable monitoring supplies ...

Determination of Exposure Levels in a Simulated Delousing Procedure (1 Percent Lindane Dust)

FEB 87

Authors: Mark W. Michie; ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

One percent lindane dust has been used as a pedinculicide for military personnel for over 30 years. It is also the only such approved item currently maintained in inventory for the control of infestations to troops in the field. Delousing of military troops is not done routinely. Dusting is done only when deemed necessary to control a possible disease outbreak, and is most likely to occur in temperate or cold ...

Topical Hazard Evaluation of Three DEET Products (N,N'-Diethyl-M- Toluamide). June-December 1986

FEB 87

Authors: John G. Harvey; ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

A Topical Hazard Evaluation of three DEET products; Airosol, Morflex Blend 1, and a manufactures blend was conducted by this Agency. Compounds were tested for primary skin irritation in rabbits and skin sensitization in guinea pigs. None of the compounds produced sensitization reactions in guinea pigs and very slight to no irritation response in rabbits.