A lysate of an immortalized monoclonal cell line derived from the striatum (X61) contains an activity that is capable of increasing the dopamine content of an immortalized, dopaminergic mouse mesencephalic cell line (MN9D). The activity can be extracted from the cell lysate by isoamyl alcohol/ chloroform. NMR spectroscopic analysis demonstrated that a purified fraction from the isoamyl alcohol/chloroform soluble dopaminergic stimulatory activity is a mixture of 80-90% cis-9-octadecenoic acid (oleic ...
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