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Reports by Author

J L Sussman


Click on the titles below to find US government-authored or -collected reports written by J L Sussman

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Project 3 - Molecular Evolution of Human PON to Design Enhanced Catalytic Efficiency for Hydrolysis of Nerve Agents Feb-2009 18 pages
Authors:  Dan Tawfik; J L Sussman; WEIZMANN INST OF SCIENCE REHOVOT (ISRAEL)
The full text of this report is available for sale.The long-term objective of this effort is to develop a generic gene shuffling-based technology to rapidly screen libraries of 1010 proteins/peptides encoded by DNA libraries, for identifying biomolecules that can intercept both existing and emerging organophosphate-based chemical warfare nerve agents (CWNA). The specific milestones for year 1 were (a) Proof of concept for the proposed technology; (b) Generation of 4-6 libraries based on recombinant PON1 and PON3 based on gene ...


Project 3 - Molecular Evolution of Human PON to Design Enhanced Catalytic Efficiency for Hydrolysis of Nerve Agents 01-Feb-2008 15 pages
Authors:  Dan Tawfik; J L Sussman; WEIZMANN INST OF SCIENCE REHOVOT (ISRAEL)
The full text of this report is available for sale.The long-term objective of this effort is to develop a generic gene shuffling-based technology to rapidly screen libraries of 1010 proteins/peptides encoded by DNA libraries for identifying biomolecules that can intercept both existing and emerging organophosphate-based chemical warfare nerve agents (CWNA). The specific milestones for year 1 were (a) Proof of concept for the proposed technology; (b) Generation of 4-6 libraries based on recombinant PON1 and PON3 based on gene ...


Total Results: 2 Results per page: