Guinea pigs inoculated with the live, M-44 vaccine strain of Coxiella burnetii were examined grossly and microscopically for the presence of Q fever-related lesions. Mild myocarditis was observed in 38% of infected, but in none of the control animals. Livers showed significant incidence of hepatitis, necrosis and granuloma formation, especially during the first eight days of the infection. A much lower incidence of splenitis was also found but was considered ...
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