Acute clinical malaria caused by Plasmodium inui was diagnosed in an adult female cynomolgus monkey (Macaca fascicularis) 4 years after importation into the United States. Severe clinical disease was attributed to activation of a chronic infection by the stress associated with experimental procedures completed 2 weeks earlier. Clinical findings included severe regenerative anemia, hepatosplenomegaly, weakness, lethargy, weight loss, and anorexia. The infection was treated and successfully eliminated with chloroquine hydrochloride, ...
Forty-three percent of 47 recently imported cynomolgus monkeys (Macaca fascicularis) were found to have malarial infections. The agent identified was Plasmodium inui. All infections were subclinical in nature. Parasitemias ranged from 10-900 parasites/cm mm of whole blood. Pre- and posttreatment hematologic values were evaluated following treatment with chloroquine. Treatment was effective in clearing parasitemias from 13 of 14 infected monkeys. Pretreatment values of hematocrit, hemoglobin and mean corpuscular volume were ...
An inguinal hernia involving the urinary bladder and omentum was detected in a Cynomolgus monkey. Surgical repair was performed. Recovery was routine. (Author)
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