| The Impact of Exercise on the Vulnerability of Dopamine Neurons to Cell Death in Animal Models of Parkinson's Disease |
Jul-2008 |
80 pages |
| Authors:
Michael J Zigmond; Amanda Smith; Anthony Liou; PITTSBURGH UNIV PA
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 | Parkinson's disease results in part from the loss of dopamine neurons. We hypothesize that exercise reduces the vulnerability of dopamine neurons to neurotoxin exposure, which is modulated by stress. We have outlined experiments to test this hypothesis in rats treated with one of several neurotoxins, beginning with 6-hydroxydopamine. Over the past year, we increased the size and training of our research team and made a number of observations of direct ... |
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| The Impact of Exercise on the Vulnerability of Dopamine Neurons to Cell Death in Animal Models of Parkinson's Disease |
01 JUL 2007 |
12 pages |
| Authors:
Michael J. Zpgmond; Amanda Smith; Anthony Liou; PITTSBURGH UNIV PA
|
| Parkinson's disease results in part from the loss of dopamine neurons. We hypothesize that exercise reduces the vulnerability of dopamine neurons to neurotoxin exposure, which is modulated by stress. We have outlined experiments to test this hypothesis in rats treated with one of several neurotoxins, beginning with 6-hydroxydopamine. Over the past year, we increased the size and training of our research team and made a number of observations of direct ... |
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| The Impact of Exercise on the Vulnerability of Dopamine Neurons to Cell Death in Animal Models of Parkinson's Disease |
JUL 2006 |
10 pages |
| Authors:
Michael J. Zigmond; Amanda Smith; Anthony Liou; PITTSBURGH UNIV PA
|
| Parkinson's disease results in part from the loss of dopamine neurons. We hypothesize that exercise reduces the vulnerability of dopamine neurons to neurotoxin exposure, whereas stress increases vulnerability. We have outlined experiments to test this hypothesis in rats treated with one of several neurotoxins, beginning with 6-hydroxydopamine. Over the past year, we increased the size and training of our research team and made a number of observations of direct relevance ... |
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| The Impact of Exercise on the Vulnerability of Dopamine Neurons to Cell Death in Animal Models of Parkinson's Disease |
JUL 2005 |
9 pages |
| Authors:
Michael J. Zigmond; Amanda Smith; PITTSBURGH UNIV PA
|
| Parkinson's disease (PD) results in part from the loss of dopamine (DA) neurons. We hypothesize that exercise reduces the vulnerability of DA neurons to neurotoxin exposure, whereas stress increases vulnerability. We have outlined experiments to test this hypothesis in rats treated with one of several neurotoxins, beginning with 6- hydroxydopamine (6-OHDA). Over the past year, we increased the size and training of our research team and made a number of ... |
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