Inflammation and edema are associated with respiratory and cutaneous exposure to sulfur mustard (SM) as well as with phosgene-induced lung injury. IL-8 is a key chemotactic inflammatory cytokine that recruits neutrophils and contributes to progression of acute lung injury caused by inhalation of these chemical agents. In the present study, human lung small airway cell (SAC) cultures were exposed to either SM 25 to 400 micrometers or phosgene 0.1 to ...
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