| Testing of the Bio-Seeq (Smiths Detection Handheld PCR Instrument): Sensitivity, Specificity, and Effect of Interferents on Yersinia Pestis Assay Performance |
APR 2005 |
25 pages |
| Authors:
Kevin P. O'Connell; Patricia E. Anderson; James J. Valdes; Jennifer R. Bucher; EDGEWOOD CHEMICAL BIOLOGICAL CENTER ABERDEEN PROVING GROUND MD RESEARCH AND TECHNOLOGY DIR
|
 | Smiths Detection-Edgewood (SDE), Inc., recently developed a handheld PCR instrument, the Bio-Seeq(Federal Registration), an updated, redesigned version of a small, portable PCR instrument previously known as Handheld Advanced Nucleic Acid Analyzer (HANAA). The SDE developed the Bio-Seeq(Federal Registration) to provide a portable platform for use by first responders to detect biological threats in civilian areas. To be ready for introduction into the marketplace, the instrument must be accompanied by a ... |
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| Testing of the Bio-Seeq (Smiths Detection Handheld PCR Instrument): Sensitivity, Specificity, and Effect of Interferents on Francisella Tulurensis Assay Performance |
DEC 2004 |
25 pages |
| Authors:
Kevin P. O'Connell; Patricia E. Anderson; James J. Valdes; Jennifer R. Bucher; EDGEWOOD CHEMICAL BIOLOGICAL CENTER ABERDEEN PROVING GROUND MD RESEARCH AND TECHNOLOGY DIR
|
| Smiths Detection-Edgewood (SDE), Inc., recently developed a hand held PCR instrument, the Bio-Seeq(Trademark), an updated, redesigned version of the small, portable PCR instrument previously known as the Handheld Advanced Nucleic Acid Analyzer (HANAA). The SDE developed the Bio-Seeq(Trademark) to provide a portable platform for first responders to use for detecting biological threats in civilian areas. To be ready for introduction into the marketplace, the instrument must be accompanied by a ... |
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| Native and Engineered Simulants for DNA Virus Threat Agent |
DEC 2004 |
6 pages |
| Authors:
Kevin P. O'Connell; Patricia E. Anderson; Michael S. Horsmon; James J. Valdes; EDGEWOOD CHEMICAL BIOLOGICAL CENTER ABERDEEN PROVING GROUND MD
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| The ability to test BW detection gear in all stages of development (lab bench, test chamber, and field) and to train using the gear in realistic situations is a cornerstone of biological defense research and operations. Better simulants will allow higher quality and more reproducible testing, as well as more realism in testing and training. There is currently only one virus widely accepted for low-level containment or field release in ... |
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| Testing of the Bio-Seeq (Smiths Detection Handheld PCR Instrument): Sensitivity, Specificity, and Effect of Interferents on Bacillus Assay Performance |
JUL 2004 |
25 pages |
| Authors:
Kevin P. O'Connell; Patricia E. Anderson; James J. Valdes; EDGEWOOD CHEMICAL BIOLOGICAL CENTER ABERDEEN PROVING GROUND MD
|
| Smiths Detection-Edgewood (SDE), Inc., recently developed a handheld PCR instrument, the Bio-Seeq(Trademark), an updated, redesigned version of the small, portable PCR instrument previously known as the Handheld Advanced Nucleic Acid Analyzer (HANAA). The SDE developed the Bio-Seeq(Trademark) to provide a portable platform for first responders to use for detecting biological threats in civilian areas. To be ready for introduction into the marketplace, the instrument must be accompanied by a menu ... |
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| Antibody Engineering for Expression in Insect Cells and Larvae |
AUG 2002 |
21 pages |
| Authors:
Patricia E. Anderson; James J. Valdes; Kevin P. O'Connell; EDGEWOOD CHEMICAL BIOLOGICAL CENTER ABERDEEN PROVING GROUND MD
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| Antibodies are currently deployed as the recognition component of sensors that detect biological threat agents. Antibodies that detect simulants of bio-threat agents are also currently incorporated into detection platforms for testing and evaluating new devices and materials. Previously, we developed an anti-botulinum toxin antibody using a powerful genetic technology known as phage display, in which a very large library of immunoglobulin (antibody) genes are expressed on the surface of bacteriophage ... |
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| Recombinant Antibodies for the Detection of Bacteriophage MS2 and Ovalbumin |
MAR 2002 |
19 pages |
| Authors:
Kevin P. O'Connell; Akbar S. Khan; Patricia E. Anderson; James J. Valdes; Sarah Cork; EDGEWOOD CHEMICAL BIOLOGICAL CENTER ABERDEEN PROVING GROUND MD
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| Antibodies are currently field-deployed as the recognition component of sensors that detect biological threat agents. Antibodies that detect simulants of biothreat agents are also incorporated into biodetection platforms for testing and evaluating new devices and materials. Previously, we developed an anti-botulinum toxin antibody using a powerful genetic technology known as phage display, in which a very large library of immunoglobulin (antibody) genes are expressed on the surface of bacteriophage (bacterial ... |
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