The current proposal aims to directly compare the psychotherapy and medication treatments for PTSD considered to have the most evidence for effectiveness. While both SSRI and PE have demonstrated efficacy, there are significant individual differences in clinical responses to both treatments. To achieve best clinical outcomes and to utilize available treatment most effectively, it is critical to examine how PTSD and related psychopathology and functional impairment change with these treatments ...
The research we have conducted over the third year of this research program is contained in this report. We have made substantial progress towards completing all of the proposed research in this program within proposed time frame i.e. final report on 9/29/12. During the last year, we have demonstrated that (1) decreases in neural activity in the BLA and hippocampus are critical for SPS-enhanced fear renewal (specific aims #1a and ...
In this report, we will demonstrate that we have a) replicated some pilot findings presented in the initial grant application, b) completed some of the proposed research in specific aims #2 and #3, and c) started research proposed in specific aim #4. We have been unable to replicate our initial SPS effect on social avoidance and freezing induced by trimethlylthiazoline (i.e. predator odor), but are still interested in exploring SPS ...
Reports by Author
