The hypothesis of this proposal is that interposition of micropatterned biodegradable polymer based nerve grafts to replace resected or damaged cavernous nerves can facilitate return of erectile function by engendering directional nerve growth in an animal model. Micropatterned grafts have been produced using a biodegradable polymer (PDFA). The groove characteristics obtained by micropatterning will be optimized to allow maximal directional neurite growth have been optimized. The effect of laminin +/- ...
The hypothesis of this proposal is that interposition of micropatterned biodegradable polymer based nerve grafts to replace resected or damaged cavernous nerves can facilitate return of erectile function by engendering directional nerve growth in an animal model. Micropatterned grafts have been produced using a biodogradable polymer (PDFA) The groove oharaotceristics obtained by micropatterning will be optimized to allow maximal directional neurite growth have been optimized The effect of laminin +/- ...
The hypothesis of this proposal is that interposition of micropatterned biodegradable polymer based nerve grafts to replace resected or damaged cavernous nerves can facilitate return of erectile function by engendering directional nerve growth in an animal model. Micropatterned grafts have been produced using a biodegradable polymer (PDFA). The groove characteristics obtained by micropatterning will be optimized to allow maximal directional neurite growth have been optimized. The effect of laminin +1- ...