This is the second year of a four-year project to evaluate neurotoxicity related to depleted uranium (DU) exposure and stress in rats. In this year, the project was modified based upon a scientific review of our project at the Force Health Protection Review of Depleted Uranium Projects. This resulted in addition of a pilot stress study, modification of the acute toxicity study and use of an en%enhanced stress model for ...
This is a three-year study on the neurotoxic potential of depleted uranium (DU) in laboratory rats. The effect of stress on DU kinetics and toxicity will also be evaluated. Previous studies with Gulf War veterans and experimental animals exposed to embedded DU suggest that neurotoxicity may result from DU exposure (McDiarmid et al. 2000; Pellmar et al.1 1999). The current investigation is designed to assess the neurotoxic potential of acute ...
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