Rats were fed diets containing HMX for 13 weeks. Dose levels for males were 0, 50, 150, 450, 1350 or 4000 mg HMX/kg/day. Female rats received 1, 50, 115, 270, 620 or 1500 mg HMX/kg/day. No deaths or clinical signs occurred attributable to dosing with HMX. Reduced body weight gains and food consumptions were observed, more so at higher dose levels. Haematological and clinical chemical observations were made only on ...
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