| Morphological Features Accompanying Neural Differentiation of Neuroblastoma (N-2A) Induced by Media Serum Availability |
24 JUL 1989 |
23 pages |
| Authors:
John Rossi Iii.; Arthur A. Messier; Elly Heyder; NAVAL SUBMARINE MEDICAL RESEARCH LAB GROTON CT
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 | Previous studies have demonstrated that cultured cloned cells extend neurites after exposure to media supplemented with reduced concentration of serum. The present experiment on cloned neuroblastoma cells (Neuro-2a) corroborates and extends the past studies. N2A cells were cultivated in media containing 10% fetal bovine serum (FBS). After 24 hrs the cells were subcultivated into media containing either 10%, 5%, or 1% FBS; or media containing 10%, 5%, or 1% NU-SERUM ... |
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| A Preliminary Study of Cardiovascular Risks in Retired Submariners, |
01 JUN 1983 |
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| Authors:
Donald V. Tappan; Douglas R. Knight; Elly Heyder; Kenneth R. Bondi; NAVAL SUBMARINE MEDICAL RESEARCH LAB GROTON CT
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 | Two sets of studies seem to agree that both retired and active duty submariners have increased levels of a personality component strongly related to cardiovascular risks and have lowered levels at least two factors associated with reduced risk. One of the explanations for negative association of risk with personality traits is that these factors may be related to 'environmental insulating mechanisms' protective against cardiovascular diseases or disease risks. The authors ... |
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| Carbohydrate Metabolism in Submariner Personnel, |
01 JUN 1983 |
6 pages |
| Authors:
Elly Heyder; L. W. Mooney; Donald V. Tappan; NAVAL SUBMARINE MEDICAL RESEARCH LAB GROTON CT
|
| Submariners have been shown to have an increased rate of glucose utilization 2 hours after an oral loading test. Relative hypoglycemia due to excess insulin production has been considered a first indication of developing diabetes. However, diabetes can not be defined in terms of blood glucose level alone but rather in its relationship to insulin release, utilization, and effectiveness, The ability to interpret insulin response to a glucose load by ... |
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| Improved Methods for Cyanide and Thiocyanate Measurements |
02 MAR 1982 |
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| Authors:
Robert M. DeBell; Michael L. Shea; Elly Heyder; Douglas R. Knight; NAVAL SUBMARINE MEDICAL RESEARCH LAB GROTON CT
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| Substantial improvements were made in procedures used for quantitative measurements of cyanide and thiocyanate. In the case of cyanide the use of Warburg flasks as reaction vessels to maintain a sealed system for gas transfer and extending the transfer period to sixty minutes permitted statistically accurate and reliable recovery of cyanide within a ten-fold range (3 to 30 nanomoles). A weak anion exchange resin requiring simple preparation was successfully used ... |
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| Biochemical Profiles of Submariners: A Longitudinal Health Study. |
15 MAY 1975 |
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| Authors:
Donald V. Tappan; Michael J. Jacey; Elly Heyder; William A. Tansey; NAVAL SUBMARINE MEDICAL RESEARCH LAB GROTON CONN
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| As part of this Laboratory's Longitudinal Health Study, the sera of 466 submariners were analyzed for 12 biochemical parameters using standardized automated procedures. In addition, a two hour glucose tolerance test was performed on each participant. Mean values of all parameters measured were within generally accepted normal clinical limits. The values for cholesterol, uric acid, inorganic phosphate, and glucose were shown to be distributed according to Gaussian probability curves. A ... |
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| Biochemical Responses to a 28-Day Interval between Exposures to Air at 6.7 ATA. |
27 NOV 1974 |
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| Authors:
Elly Heyder; Donald V. Tappan; NAVAL SUBMARINE MEDICAL RESEARCH LAB GROTON CONN
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| The study concerns an evaluation of the possible effects of repetitive diving and long-term effects of compression/decompression on distribution of, or loss of minerals, electrolytes, and protein metabolites in men subjected to standard Navy diving procedures. Urinary minerals, electrolytes, nitrogen metabolites and steroids, as well as serum minerals and electrolytes, were measured in Navy divers following short exposures to air at 6.7 ATA. A comparison was made between two similar ... |
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| Biochemical Responses of Men to Simulated Air Dives of 100 Feet. |
19 MAR 1974 |
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| Authors:
Donald V. Tappan; Elly Heyder; NAVAL SUBMARINE MEDICAL RESEARCH LAB GROTON CONN
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| Six men were subjected to a simulated dive in air to 100 FSW for one hour followed by a 70-minute decompression. Total 24 hour excretions of 12 urinary parameters were measured for two days prior to and 11 days following the dives. Blood serum constituents were determined in pre-dive samples, in samples taken immediately upon reaching the surface and in sera obtained for 9 post-dive days. Urinary hydroxyproline increased on ... |
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| Animal Saturation Diving at Simulated Depths of 50 and 60 Feet: Description of Operation and Environment. |
05 FEB 1974 |
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| Authors:
Robert D. Murray; Shannon D. Stewart; Elly Heyder; George M. Adams; NAVAL SUBMARINE MEDICAL RESEARCH LAB GROTON CONN
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| Two simulated saturation dives were conducted to monitor the physiological and biochemical responses of a model animal system to long-term diving in compressed air. The dives were performed at 50 and 60 feet of sea water for 60 and 36 days, respectively. Mean chamber CO2 was 0.42% and 0.33% surface equivalent concentration for the 50- and 60-foot dives, respectively. Mean chamber O2 was .51 ata and .58 ata for the ... |
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| Excretion of Minerals and Nitrogen Metabolites Following Exposure to Increased Air Pressure (2 or 7 ATA). |
10 OCT 1973 |
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| Authors:
Elly Heyder; Donald V. Tappan; NAVAL SUBMARINE BASE NEW LONDON GROTON CONN
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| Urinary minerals, electrolytes, nitrogen metabolites and steroids were measured in Navy divers following exposure to air at 2 and 7 ATA for 45 minutes. Total urinary excretion of osmoles, sodium, potassium, calcium, phosphorus, urea nitrogen, uric acid, creatinine, keto- and ketogenic steroids were depressed below control values during the first day following exposure to either 2 or 7 ATA. The mineral and electrolyte changes are related to reduction in urine ... |
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| Studies of Calcium and Inorganic Phosphorus Levels in Plasma and Erythrocytes During Acute and Chronic Hypercapnia. |
29 FEB 1972 |
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| Authors:
Elly Heyder; NAVAL SUBMARINE MEDICAL RESEARCH LAB GROTON CONN
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| To ascertain the effects of acute and chronic hypercapnia on blood levels of calcium (Ca) and inorganic phosphorus (Pi), guinea pigs were exposed to 1%, 3%, and 15% CO2 for various periods up to seven days. Plasma and RBC Ca and Pi and serum ionized Ca were determined. Blood from submariners exposed to up to 1% CO2 for three weeks, followed by one-week recovery, was analyzed for plasma electrolytes and ... |
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