The synthesis of the polyamines phosphorothioic acids NH2(CH2)n''NH(CH2)n'NH(CH2)nSPO3H were achieved where n = 2 and 3, n' = 2, 3, 4 and 5; n'' = 2, 3, 4. The toxicities and radiation dose reduction factors (DRF) were determined in mice. The compounds were given intraperitoneally before irradiation. The mice were irradiated with Cs134 gamma radiation source at dose rate of approximately 90 r/min. The best DRF (1.8) was obtained for ...