| The Use of a Low-Concentration Heparin Solution to Extend the Life of Central Venous Catheters in the African Green Monkeys (Chlorocebus aethiops) |
28 NOV 2006 |
4 pages |
| Authors:
Christopher S. Gamble; Kenneth O. Jacobsen; Elizabeth K. Leffel; M. L. Pitt; ARMY MEDICAL RESEARCH AND MATERIEL COMMAND FORT DETRICK MD
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 | Normal hematological values for African green monkeys have been reported, but these results are confounded by the effect of chemical restraint (ketamine), physical restraint, and capture stress. The dual-lumen central venous catheter, jacket, and tether combination described allows intravenous fluid administration and repeated blood sampling without using restraint or anesthesia. The use of a low-concentration heparin solution for catheter maintenance resulted in a significant increase in mean patency time compared ... |
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| Short-Course Postexposure Antibiotic Prophylaxis Combined with Vaccination Protects Against Experimental Inhalational Anthrax |
16 MAY 2006 |
5 pages |
| Authors:
Nicholas J. Vietri; Bret K. Purcell; James V. Lawler; Elizabeth K. Leffel; Pedro Rico; Christopher S. Gamble; Nancy A. Twenhafel; Bruce E. Ivins; Mary E. Wright; Arthur M. Friedlander; ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK MD
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| Prevention of inhalational anthrax after Bacillus anthracis spore exposure requires a prolonged course of antibiotic prophylaxis. In response to the 2001 anthrax attack in the United States, ~10,000 people were offered 60 days of antibiotic prophylaxis to prevent inhalational anthrax, but adherence to this regimen was poor. We sought to determine whether a short course of antibiotic prophylaxis after exposure could protect non-human primates from a high-dose spore challenge if ... |
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| Short-Course Postexposure Antibiotic Prophylaxis Combined with Vaccination Protects Against Experimental Inhalational Anthrax |
16 MAY 2006 |
7 pages |
| Authors:
Nicholas J. Vietri; Bret K. Purcell; James V. Lawler; Elizabeth K. Leffel; Pedro Rico; Christopher S. Gamble; Nancy A. Twenhafel; Bruce E. Ivins; Henry S. Heine; Ryan Sheeler; ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK MD
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| Prevention of inhalational anthrax after Bacillus anthracis spore exposure requires a prolonged course of antibiotic prophylaxis. In response to the 2001 anthrax attack in the United States, approximately 10,000 people were offered 60 days of antibiotic prophylaxis to prevent inhalational anthrax, but adherence to this regimen was poor. We sought to determine whether a short course of antibiotic prophylaxis after exposure could protect non-human primates from a high-dose spore challenge ... |
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