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Reports by Author

Alan Derr


Click on the titles below to find US government-authored or -collected reports written by Alan Derr

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Genomic Patterns of Pathogen Evolution Revealed by Comparison of Burkholderia pseudomallei, the Causative Agent of Melioidosis, to Avirulent Burkholderia thailandensis 26 MAY 2006 19 pages
Authors:  Yiting Yu; H. S. Kim; Hui H. Chua; Chi H. Lin; Siew H. Sim; Daoxun Lin; Alan Derr; Reinhard Engels; David DeShazer; Bruce Birren; ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK MD
The full text of this report is available for sale.The Gram-negative bacterium Burkholderia pseudomallei (Bp) is the causative agent of the human disease melioidosis. To understand the evolutionary mechanisms contributing to Bp virulence, we performed a comparative genomic analysis of Bp K96243 and B. thailandensis (Bt) E264, a closely related but avirulent relative. RESULTS: We found the Bp and Bt genomes to be broadly similar, comprising two highly syntenic chromosomes with comparable numbers of coding regions (CDs), protein family ...


Improved HMM Models for High Performance Speech Recognition 1989 8 pages
Authors:  Steve Austin; Chris Barry; Yen-Lu Chow; Alan Derr; Owen Kimball; Francis Kubala; John Makhoul; Paul Placeway; William Russell; Richard Schwartz; George Yu; BBN SYSTEMS AND TECHNOLOGIES CORP CAMBRIDGE MA
The full text of this report is available for sale.In this paper we report on the various techniques that we implemented in order to improve the basic speech recognition performance of the BYBLOS system. Some of these methods are new, while others are not. We present methods that improved performance as well as those that did not. The methods include Linear Discriminant Analysis, Supervised Vector Quantization, Shared Mixture VQ. Deleted Estimation of Context Weights, MMI Estimation Using "N-Best" Alternatives, ...


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