Acetazolarnide (AZ) can be taken at sea level (SL) to prevent acute mountain sickness during subsequent altitude (ALT) exposure. AZ causes metabolic acidosis at SL and ALT, and increases arterial oxygen saturation (SaO2) at ALT. HYPOTHESIS: AZ will impair muscle endurance at SL but not ALT (4300 m, <3 h). METHODS: Six subjects (2012 yr; Xl SD) performed exhaustive constant work rate 1-leg knee extension exercise (2512 watts) once per ...
In order to simulate the expected environmental conditions in a submarine that has become disabled (i.e., loss of electrical power and subsequent inability to control temperature, humidity, and oxygen and carbon dioxide levels), a system was created to control the oxygen and carbon dioxide concentration of an environmental chamber. The study protocol called for a baseline testing period of ambient environmental conditions for 2 days (20 deg C, 50% RH, ...
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