| The Use of Tympanometry to Detect Aerotitis Media in Hypobaric Chamber Operations |
31 JAN 92 |
31 pages |
| Authors:
V. A. Forte Jr.; J. A. Devine; P. B. Rock; A. Cymerman; ARMY RESEARCH INST OF ENVIRONMENTAL MEDICINE NATICK MA
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 | Diagnosis and quantification of aerotitis media were performed using a modified commercially-available tympanometer under hypobaric conditions. Subjects were-22 males and 9 females, 22-43 years of age who were tested in each ear with the tympanometer prior to and after exposure, sequentially at the barometric pressure plateaus of 706, 656, 609, 586, 564, and 522 mm Hg, and following an induced ear block during a 1-min descent from 522 to 586 ... |
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| Cognitive Performance, Mood States, and Altitude Symptomatology in 13- 21% Oxygen Environments |
01 JUN 88 |
45 pages |
| Authors:
B. L. Shukitt; R. L. Burse; L. E. Banderet; D. R. Knight; A. Cymerman; ARMY RESEARCH INST OF ENVIRONMENTAL MEDICINE NATICK MA
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| To reduce the risk of and damage from fires, naval engineers have suggested reducing the oxygen concentration in submarines below the normal ambient level of 21% (PO2 = 159 torr). However, reductions to 13% oxygen (PO2 = 99 torr) may produce decrements in mental and physical performance, changes in mood states, or symptoms of acute mountain sickness (AMS). To investigate these possibilities, thirteen male sailors were confined and tested in ... |
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| The Effect of Spironolactone on the Cardiocirculatory Responses to Upright Tilt at Sea Level and at Simulated High Altitude |
19 JUN 85 |
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| Authors:
C. S. Fulco; R. Larsen; P. B. Rock; A. J. Young; A. Cymerman; ARMY RESEARCH INST OF ENVIRONMENTAL MEDICINE NATICK MA
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 | The objective of this study was to determine if spironolactone (S) alters the cardiocirculatory responses to upright tilt at sea level (SL;50m) and during 44 hours of simulated altitude (HA;4600m). In a double-blind, crossover- designed study, 9 male subjects (age range: 18-25 years) received 25 mg orally, 4x/day of either S or an identically-appearing placebo (P) 2 days prior to and during HA. The crossover was separated by two weeks. ... |
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| An Environmentally-Controlled Extended-Use Small Animal Hypobaric Chamber |
21 MAR 85 |
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| Authors:
J. A. Devine; A. Cymerman; ARMY RESEARCH INST OF ENVIRONMENTAL MEDICINE NATICK MA
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| An environmentally-controlled extended-use small animal hypobaric chamber has been designed to study small laboratory animals at low barometric pressures for long periods of exposure. The rectangular chamber (91.4 x 71.1x 50.8 cm) is constructed of aluminum plate and acrylic resin, with a volume of 32.3 cc3. A computer/data acquisition control unit provides for controlling and collecting data on pressure, temperature and relative humidity (RH) for an indefinite period of time. ... |
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| The Effect of Naproxen on Acute Mountain Sickness and Vascular Responses to Hypoxia |
15 AUG 1984 |
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| Authors:
R. T. Meehan; A. Cymerman; P. Rock; C. S. Fulco; J. Hoffman; ARMY RESEARCH INST OF ENVIRONMENTAL MEDICINE NATICK MA
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| The role of prostaglandins in the pathogenesis of acute mountain sickness and two hypoxia-induced vascular responses was evaluated using the cyclooxygenase inhibitor naproxen. Eleven males spent 24h at sea level, followed by 34h of decompression to 428 torr while receiving naproxen (N), 250 mg twice daily or placebo (P) in a double-blind crossover trial. Serum naproxen levels by high pressure liquid chromatography were not changed by hypoxia. Retinal artery diameter ... |
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| The Influence of Cardiorespiratory Fitness on the Decrement in Maximal Aerobic Power at High Altitude |
11 JUN 1984 |
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| Authors:
A. J. Young; A. Cymerman; R. L. Burse; ARMY RESEARCH INST OF ENVIRONMENTAL MEDICINE NATICK MA
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| There are conflicting reports in the literature which imply that the decrement in maximal aerobic power experienced by a sea-level (SL) resident sojourning at high altitude (HA) is either smaller or larger for the more aerobically fit person. In the present study, data collected during several investigations conducted at an altitude of 4300 m were analyzed to determine if the level of aerobic fitness influenced the decrement in maximal oxygen ... |
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| Sparing Effect of Chronic High-Altitude Exposure on Muscle Glycogen Utilization During Exercise |
16 JUN 1981 |
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| Authors:
A. J. Young; W. J. Evans; A. Cymerman; K. B. Pandolf; J. J. Knapik; ARMY RESEARCH INST OF ENVIRONMENTAL MEDICINE NATICK MA
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| Substrate utilization during heavy (approx. 85% VO2 max) bicycle exercise was examined in eight low-altitude residents at sea level (SL) and after acute (2 hours) and chronic (18 days) exposure to 4,300 m (HA). Mean VO2 max was approx. 27% lower with acute HA than at SL and did not change significantly with continued HA exposure. Biopsies from the vastus lateralis muscle and venous blood samples were obtained before and ... |
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| Evidence for Increased Intrathoracic Fluid Volume in Man at High Altitude, |
13 SEP 1978 |
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| Authors:
James J. Jaeger; J. T. Sylvester; A. Cymerman; J. T. Maher; J. J. Berberich; ARMY RESEARCH INST OF ENVIRONMENTAL MEDICINE NATICK MASS
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| To determine if subclinical pulmonary edema occurs commonly at high altitude, 25 young male soldiers participated in a strenuous, 72 h field exercise at low altitude (200 to 875 m) and in a similar exercise one week later at high altitude (3000 to 4300 m). At 0, 36, and 72 h of each phase the subjects were given a physical examination, a chest radiograph was taken, and the following measurements ... |
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