Pain is a common and distressing symptom that impacts the quality of life of many patients with neurofibromatosis. The pain is often due to the formation of a neuroma. To understand better how neuromas cause pain and what treatments may be provided, we have developed an animal model of a painful neuroma. The tibial neuroma transposition (TNT) model has been confirmed as a model of neuropathic pain. The TNT model ...
Formation by dip coating of highly ordered and closely packed, self assembled monolayers (SAMs) of microsized silica spheres has been reported. Under optimized coating conditions, SAMs were formed with 2 micron diameter silica spheres on record-breakingly large areas, measuring 3x10 mm2 on silicon substrates and 1.5x11 mm2 on glass substrates. The SAMs structure and their spatial extension were significantly influenced by the concentration of the solution, withdrawal speed, immersion time, ...
Pain is a common and distressing symptom that impacts the quality of life of many patients with neurofibromatosis. The pain is often due to the formation of a neuroma. To understand better how neuromas cause pain and what treatments may be provided, we have developed an animal model of a painful neuroma. The tibial neuroma transposition (TNT) model has been confirmed as a model of neuropathic pain. The TNT model ...