An increasingly important issue in force protection is the toxicology associated with toxic chemical and mixture exposure at uncharacterized deployed sites. Current methods for determining or monitoring toxic exposures to the warfighter in their working or living environment are not adequate to prevent serious health effects. Deployed personnel may be exposed to toxic chemicals as a result of industrial accidents, intentional or unintentional activities of enemy or friendly forces or ...
Toxicogenomic profiling is a molecular approach to capture the global, transcriptomic response of a biological system caused by perturbations resulted from chemical exposure. Coupled with advanced bioinformatic techniques, it allows for the elucidation of the molecular mechanisms of chemical toxicity, as well as the identification of novel biomarkers predictive for chemical exposure. In an effort to investigate if gene expression changes in whole blood can serve as novel biomarkers indicative ...
Reports by Author
