We are testing the hypothesis that a model parasite gene therapy vector can be genetically altered to safely, specifically and effectively target breast cancer cells in vitro and in vivo. The primary purpose and scope of this IDEA award project is to experimentally examine approaches to safely target the Toxoplasma gondii parasite gene therapy vector to breast cancer tissue using in vitro and in vivo models. We found that cytosine ...
We are testing the hypothesis that a model parasite gene therapy vector can be genetically altered to safely, specifically and effectively target breast cancer cells in vitro and in vivo. We have developed a novel strategy to establish the protozoan parasite T. gondii as the next generation vector for breast cancer gene therapy. The significant innovative aspect of this approach is the promise of this strategy to deliver a novel ...
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