The primary objective of this research is to develop new techniques in single photon emission computed tomography (SPECT) breast cancer imaging providing improved detection and characterization of early stage breast cancer. Projection data were acquired by implementing a tiltable SPECT system on a breast and torso phantom. The data were reconstructed with both an ordered subset expectation maximization (OSEM) algorithm and a filtered backprojection (FBP) algorithm with a ramp filter. ...