Manganese (Mn) and iron are essential metals for normal growth and development that compete for and share the same transporters. Thus, during periods of low dietary iron intake, the transport and deposition of Mn in the brain are increased. Conversely, high-risk populations for Mn intoxication, namely Mn miners and welders, may benefit from iron supplementation, which may lower their central nervous system (CNS) Mn burden. For the first 3 years, ...
The Administrative Core includes Dr. Michael Aschner of Vanderbilt University Medical Center as the Principal Investigator (PI), and an Administrative Assistant. The Administrative Core is involved in all facets of the MHRP, ensuring proper allocation of funds to the various Research and Support Cores, required financial reporting to the Army, facilitation of the communication between the various CPIs (Core Principal Investigators), timely reporting of the results, communication with all relevant ...
The Administrative Core includes Dr. Michael Aschner of Vanderbilt University Medical Center as the Principal Investigator (PI), and an Administrative Assistant. The Administrative Core is involved in all facets of the MHRP, ensuring proper allocation of funds to the various Research and Support Cores, required financial reporting to the Army, facilitation of the communication between the various CPIs (Core Principal Investigators) timely reporting of the results, communication with all relevant ...
Recent studies of Gulf War veterans with depleted uranium (DU) embedded fragments in their soft tissues point to DU-induced effects on neurobehavioral and cognitive function. These observations are corroborated by electrophysiological changes in hippocampal slices isolated from rats embedded with DU fragments. Notably, studies from the same group also suggest, for the first time, that uranium accumulates within brain tissue. It is presently unknown how uranium is transported into the ...