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Abstract:
The principal investigator was funded via a Physician-Scientist Training Award to participate in a comprehensive training plan to foster the transition to independent clinical breast cancer researcher. This plan included 1) conduct of a prospective study examining modifiers of the efficacy of risk- reducing salpingo-oophorectomy for the prevention of breast and ovarian cancer in carriers of BRCA mutations; and 2) participation in coursework in research methodology, biostatistics, molecular biology, and ethics. Progress from 5/1/ 2003 - 4/30/2004 includes: 1) Accrual at a greater than expected rate to the planned research study; 2) Participation in a clinical cancer research methods course with production of a new research proposal for the Gynecologic Oncology Group; 3) Co-authored manuscript examining prostate cancer risk of men with BRCA mutations; and 4) Conducted a pilot study suggesting that women from BRCA- negative hereditary breast cancer families are not at increased risk for ovarian cancer.
| Limitations: |
 APPROVED FOR PUBLIC RELEASE |
| Description: |
Annual summary rept. 1 May 2003-30 Apr 2004 |
| Pages: |
31 |
| Report Date: |
MAY 2004 |
| Contract Number: |
DAMD17-03-1-0375 |
| Report Number: |
A877624 |
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