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MedicineMedicine and Medical Research

HTLV-I Seroconversion Study

Authors: Stephanie K. Brodine; NAVAL HEALTH RESEARCH CENTER SAN DIEGO CA
Abstract:
A study site was established on Okinawa, a hyperendemic area for the human T-cell leukemia virus-I (HTLV-1), for the purpose of studying the risk of HTLV-I transmission to the active duty personnel stationed there. Research activities completed include an HTLV-I seroprevalence survey and a prospective study for HTLV seroconversion. A cross-sectional HTLV serologic survey was conducted among 5,255 active duty U.S. Marines on permanent tour stationed in Okinawa, Japan to search for risk factors of seropositivity. Participants were primarily young, Caucasian males. Three (0.06%) were confirmed positive for HTLV by western blot (WB) analysis, showing reactivity for core and envelope. All 3 seropositive cases have a history of prolonged sexual contact with Okinawan women, and two of the three are married to infected Okinawan RA 1, Seroconversion, Epidemiology

Limitations: APPROVED FOR PUBLIC RELEASE
Description: Annual rept. (Final) 15 Nov 87-30 Sep 91
Pages: 71
Report Date: 25 AUG 92
Report Number: A850652
Keywords relating to this report:
*LEUKEMIA
*T LYMPHOCYTES
*VIRUS DISEASES
ACTIVE DUTY
CAUCASIANS
CELLS
CORES
EPIDEMIOLOGY
HEPATITIS
HISTORY
HUMANS
INFECTIOUS DISEASE TRANSMISSION
JAPAN
MALES
OKINAWA
PERSONNEL
REACTIVITIES
RISK
SEROLOGY
SITES
SURVEYS
SYPHILIS
WOMEN
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