Abstract: The filter's physical (PRE) and viable removal efficiencies (VRE) were investigated with challenges of MS2 bacteriophage aerosols, and the infectivity of MS2 collected on the filter was analyzed. To test a proposed inactivation mechanism, media containing thiosulfate or bovine serum albumin (BSA) were put in impingers to quench and consume I2 released from the filter. In direct plating experiments, treated filters presented significantly higher VREs than did untreated filters; however, collection in excel BSA decreased VRE by half and in thiosulfate the apparent VRE decreased drastically. No significant difference in infectivity of retained viruses on treated and untreated filters was observed at the same environmental condition. Evidence presented herein for competition by dissolved I2. It also requires that dissociation of iodine from the filter and capture of iodine by MS2 aerosols as they pass through the filter be factored in the design of the assessment methodology. The filter's strong retention capability minimizes reaerosolization but also makes it difficult to discriminate the antimicrobial effect at the surface.
| Limitations: |
 APPROVED FOR PUBLIC RELEASE |
| Description: |
Journal Article PREPRINT |
| Pages: |
40 |
| Report Date: |
Apr-2009 |
| Contract Number: |
FA8650-06-C-5913 FA865006C5913 |
| Report Number: |
A849005 |
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