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ChemistryPolymer Chemistry

Oligonucleofide Imprinting in Aqueous Environment

Authors: Dolly Batra; Kenneth J. Shea; CALIFORNIA UNIV IRVINE DEPT OF CHEMISTRY
 
Abstract: The development of synthetic receptors that recognize nucleotide bases and their derivatives is an important area of research 1-3. Applications are envisioned in separation science, biosensors, drug therapy and genetic engineering. Previously in this laboratory, we have developed a molecularly imprinted synthetic receptor for 9-ethyladenine (9-EA). The network polymer has an affinity for adenine and its derivatives with an average association constant (K(a)) of 75,000 M(-1) in CHCl3.

Description: Conference paper
Pages: 8
Report Date: 21 MAY 2003
Report Number: P706310

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Keywords relating to this report:
*POLYMERS
ADENINE
AQUEOUS SOLUTIONS
Formulations_Chemistry_
GUANINE
MACROMOLECULES
MONOMERS
NUCLEOTIDES
OLIGOMERS
ORGANIC SOLVENTS
PHOSPHITES
POLYMERIZATION
SOLVATION
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