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Abstract:
Genetic and gene expression profiling based diagnosis promises to refine (1) and potentially revolutionize (2) the existing cancer staging system and the management of early disease. Microarray-based gene expression profiling and Array-based Comparative Genomic Hybridization (array-CGH) offers global views of cancer genomes and transcriptomes by detecting amplification or deletion of cancer genes (3-10), whereas techniques like real time PCR (11) can be used for validation and quantification of the identified genomic changes.
| Limitations: |
 APPROVED FOR PUBLIC RELEASE |
| Description: |
Final addendum rept. 1 Jul 2006-30 Jun 2007 |
| Pages: |
71 |
| Report Date: |
JUL 2007 |
| Contract Number: |
DAMD170310240 |
| Report Number: |
A678374 |
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