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Abstract:
The objective was to develop a rapid, reliable and simple screening assay of broad scope and sensitivity for applications in the identification of compounds with potential therapeutic value in the treatment of intoxication induced by a variety of sodium channel neurotoxins. The assay should also be able to accommodate the screening of large numbers of samples. These requirements have been met in the form of an in vitro radioligand binding assay in which the binding of a tritiated analog of bactrochotoxin serves as a sensitive indicator of test compound inter
| Limitations: |
 APPROVED FOR PUBLIC RELEASE |
| Description: |
Annual rept. 1 Jan-31 Dec 86 |
| Pages: |
32 |
| Report Date: |
03 FEB 87 |
| Contract Number: |
DAMD17-86-C-6057 |
| Report Number: |
A570971 |
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Keywords relating to this report:
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