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Optics and AcousticsLasers and Masers

Prospects for a Novel Ultrashort Pulsed Laser Technology for Pathogen Inactivation

Authors: Shaw-Wei D Tsen; Tzyy C Wu; Juliann G Kiang; Kong-Thon Tsen; UNIFORMED SERVICES UNIV OF THE HEALTH SCIENCES BETHESDA MD DEPT OF MEDICINE
Abstract:
The threat of emerging pathogens and microbial drug resistance has spurred tremendous efforts to develop new and more effective antimicrobial strategies. Recently, a novel ultrashort pulsed (USP) laser technology has been developed that enables efficient and chemical-free inactivation of a wide spectrum of viral and bacterial pathogens. Such a technology circumvents the need to introduce potentially toxic chemicals and could permit safe and environmentally friendly pathogen reduction, with a multitude of possible applications including the sterilization of pharmaceuticals, blood products, and the generation of attenuated or inactivated vaccines.

Limitations: APPROVED FOR PUBLIC RELEASE
Description: Journal article
Pages: 27
Report Date: 06 Jul 2012
Report Number: A449365
Keywords relating to this report:
ANTIMICROBIAL AGENTS
BACTERIA
BLOOD
CHEMICALS
DRUGS
EFFICIENCY
ENVIRONMENTS
INACTIVATION
LASERS
MICROORGANISMS
PATHOGENESIS
PATHOGENIC MICROORGANISMS
PULSED LASERS
REPRINTS
SAFETY
SHORT PULSES
SPECTRA
STERILIZATION
STRATEGY
THREATS
TOXICITY
VACCINES
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