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MedicineAnatomy and Physiology

Long Term Effects Retinal Laser Lesions: Multifocal ERGs (Electroretinogram) and Vernier Visual Evoked Potentials (VEPs)

Authors: Elmar T. Schmeisser; ANALYTIC SCIENCES CORP SAN ANTONIO TX
Abstract:
Seven Cynomolgus Fasciculata who had graded laser lesions placed in one eye only 6 years previously were evaluated by electro-physiological recording techniques. All animal recordings were performed under IACUC approved protocols. The single q-switched pulses from a neodymium-YAG laser produced lesions of 4 types at the time of placement: no visible change, minimal visible lesions, "white dot" lesions (localized circumscribed retinal blanching) and "red dot" lesions (contained retinal hemorrhage). Single exposures had been made both foveally and at 5 degrees eccentricity in the parafovea superiorly, inferiorly and temporally. The multifocal (perimetric) electiroretinogram was recorded from specialized contact lenses through hospital grade amplifiers.

Limitations: APPROVED FOR PUBLIC RELEASE
Description: Final rept. 95-97
Pages: 23
Report Date: MAR 1998
Contract Number: F33615-92-C-0017
Report Number: A420143
Keywords relating to this report:
*LASERS
*LESIONS
*MONKEYS
*RETINA
*VISIBILITY
ANIMALS
ELECTRORETINOGRAPHY
EYE
FOVEA
HEMORRHAGE
NEODYMIUM LASERS
Q SWITCHING
RECORDING SYSTEMS
YAG LASERS
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