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ChemistryToxicology

Dinoflagellate Toxins Responsible for Ciguatera Food Poisoning

Authors: Donald M. Miller; SOUTHERN ILLINOIS UNIV AT CARBONDALE DEPT OF PHYSIOLOGY
 
Abstract: During the four years of contract over 600 grams dry weight of the dinoflagellate Gambierdiscus toxicus was grown in large scale culture. Chemosystematic studies resulted in information which allowed improvements in both culturing and toxin production. Gram levels of cells and toxic extracts were processed in an effort to improve toxin production by G. toxicus, NMR characterization of suspected toxin was completed and partially analyzed. Crude and semi-purified toxins were delivered.

Limitations: APPROVED FOR PUBLIC RELEASE
Description: Final rept. 1 Dec 86-31 Mar 91
Pages: 225
Report Date: 30 MAR 91
Contract Number: DAMD17-87-C-7002
Report Number: B395751
Keywords relating to this report:
CULTURE
DINOFLAGELLATA
FOOD POISONING
NUCLEAR MAGNETIC RESONANCE
PHYTOTOXINS
PRODUCTION
PURIFICATION
TOXICITY
TOXINS AND ANTITOXINS
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