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ComputersComputer Programming and Software

Tool Integration Framework for Bio-Informatics

Authors: Sandeep Neema; VANDERBILT UNIV NASHVILLE TN
Abstract:
Experience in developing tool integration solutions for engineer domains indicates that the key ingredient for robust tool integration is semantically precise definition of interchange format. The project described in this report developed a robust, scalable, extensible, and standards-based tool integration framework for systems biology applications. Model-based techniques were developed and applied to formally and precisely define the interchange formats using metamodels and semantic well-formedness rules. These interchange formats were used for integrating diverse systems biology computational tools. The report describes the tool integration framework, interchange formats, and applications to representative systems biology workflows.

Limitations: APPROVED FOR PUBLIC RELEASE
Description: Final technical rept. Mar 2005-Oct 2006
Pages: 29
Report Date: APR 2007
Contract Number: FA87500520097, DARPAORDERT713
Report Number: A199964
Keywords relating to this report:
APPLICATION PROGRAMMING INTERFACE
BIOLOGY
EMBEDDED SYSTEMS
EXPERIMENTAL DATA
INTEGRATION
LIBRARIES
MARKUP LANGUAGES
METADATA
MODELS
NETWORKS
QUALITY CONTROL
RULE BASED SYSTEMS
SEMANTICS
SOFTWARE TOOLS
STATE OF THE ART
TIME SERIES ANALYSIS
TRANSCRIPTION GENETICS
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